| Patent application number | Description | Published |
|---|
| 20080213843 | Glucoamylase Variants - The invention relates to a variant of a parent fungal glucoamylase, which exhibits altered properties, in particular improved thermal stability and/or increased specific activity. | 09-04-2008 |
| 20080279980 | Fungamyl-like Alpha-Amylase Variants - The invention relates to a variant of a parent Fungamyl-like fungal alpha-amylase, which exhibits improved thermal stability at acidic pH suitable for, e.g., starch processes. | 11-13-2008 |
| 20080293120 | LIPOLYTIC ENZYMES VARIANTS - The inventors have developed improved polypeptides by substituting or deleting specified amino acids in fungal lipolytic enzymes. More particularly, the polypeptides result in a reduction of dough stickiness when they are added to a dough. The polypeptides may particularly have activity on polar lipids. | 11-27-2008 |
| 20080311242 | VARIANT LIPOLYTIC ENZYMES - The inventors have developed improved polypeptides by substituting or deleting specified amino acids in fungal lipolytic enzymes. More particularly, the polypeptides result in a reduction of dough stickiness when they are added to a dough. The polypeptides may particularly have activity on polar lipids. | 12-18-2008 |
| 20080317726 | Proteases for Pharmaceutical Use - The pharmaceutical use of proteases related to amino acids 1-274 of SEQ ID NO: 2, the serine protease derived from | 12-25-2008 |
| 20090029004 | PHYTASE VARIANTS - The present invention relates to phytase variants derived from a parent phytase which is homologous to a | 01-29-2009 |
| 20090029440 | Lipase Variants - The invention provides variant lipases, preferably, variants with reduced tendency to odor generation obtained by introducing mutations in one or more regions identified in a parent lipase. | 01-29-2009 |
| 20090035293 | Amylases for Pharmaceutical Use - The pharmaceutical use of amylases related to | 02-05-2009 |
| 20090047266 | Lipases for Pharmaceutical Use - The pharmaceutical use of lipases related to a variant of the | 02-19-2009 |
| 20090047384 | LIPOLYTIC ENZYME VARIANTS - The substrate specificity of a lipolytic enzyme can be modified by making alterations to the amino acid sequence in a defined region of the lipolytic enzyme, so as to increase the level of a desired activity or to decrease the level of an undesired activity. Thus, the inventors have developed lipolytic enzyme variants with a modified amino acid sequence with a substrate specificity which can be tailored for specific uses. | 02-19-2009 |
| 20090143270 | ALPHA-AMYLASE VARIANT WITH ALTERED PROPERTIES - The present invention relates to variants (mutants) of parent Termamyl-tike alpha-amylases, which variant has alpha-amylase activity and exhibits altered properties relative to the parent alpha-amylase. | 06-04-2009 |
| 20090148893 | Novel Subtilases - The present invention relates to methods for producing variants of a parent TY145 subtilase and of a parent BPN′ subtilase and to TY145 and BPN′ variants having altered properties as compared to the parent TY145/BPN′ subtilase. | 06-11-2009 |
| 20090203568 | DETERGENT COMPOSITIONS - The present invention relates to detergent compositions comprising a detergent ingredient and a specific lipase variant with reduced potential for odor generation and a good relative performance versus the parent lipase. | 08-13-2009 |
| 20100047388 | Lipolytic Enzyme Variants - The inventors have developed improved polypeptides by substituting or deleting specified amino acids in fungal lipolytic enzymes. More particularly, the polypeptides result in a reduction of dough stickiness when they are added to a dough. The polypeptides may particularly have activity on polar lipids. | 02-25-2010 |
| 20100135978 | Proteases for Pharmaceutical Use - The pharmaceutical use of proteases related to amino acids 1-274 of SEQ ID NO: 2, the serine protease derived from | 06-03-2010 |
| 20100136653 | CREATION OF DIVERSITY IN POLYPEPTIDES - The inventors realized that the diversity generated by conventional methods may be limited by steric hindrance between amino acid residues in the three-dimensional structures of the resulting polypeptides. The steric hindrance may occur between amino acid residues at widely different positions in the amino acid sequences, e.g. between residues in two different domains of the 3D structure, and resulting polypeptides which include such steric hindrance may never be observed in the conventional recombination methods because they may be expressed in poor yields or may have poor activity or stability. | 06-03-2010 |
| 20100136655 | FUNGAL ALPHA-AMYLASE VARIANTS - The inventors have developed a method of altering the amino acid sequence of a fungal alpha-amylase to obtain variants, and they have used the method to construct such variants. The variants may be useful for anti-staling in baked products. Accordingly, the invention provides a method of constructing fungal alpha-amylase variants based on a comparison of three-dimensional (3D) structures of the fungal alpha-amylase and a maltogenic alpha-amylase. One or both models includes a substrate. The invention also provides novel fungal alpha-amylase variants. | 06-03-2010 |
| 20100162491 | DETERGENT COMPOSITIONS - The present invention relates to detergent compositions comprising a detergent ingredient and a lipase variant with reduced potential for odor generation obtained by introducing mutations in one or more regions identified in a parent lipase. | 07-01-2010 |
| 20100291262 | Lipolytic Enzyme Variants - The substrate specificity of a lipolytic enzyme can be modified by making alterations to the amino acid sequence in a defined region of the lipolytic enzyme, so as to increase the level of a desired activity or to decrease the level of an undesired activity. Thus, the inventors have developed lipolytic enzyme variants with a modified amino acid sequence with a substrate specificity which can be tailored for specific uses. | 11-18-2010 |
| 20110003364 | SUBTILASES - The present invention relates to methods for producing variants of a parent TY145 subtilase and of a parent BPN′ subtilase and to TY145 and BPN′ variants having altered properties as compared to the parent TY145/BPN′ subtilase. | 01-06-2011 |
| 20110045572 | PROTEIN VARIANTS HAVING MODIFIED IMMUNOGENICITY - The present invention relates to a method of selecting a protein variant having modified immunogenicity as compared to the parent protein comprising the steps obtaining antibody binding peptide sequences, using the sequences to localise epitope sequences on the 3-dimensional structure of parent protein, defining an epitope area including amino acids situated within 5 Å from the epitope amino acids constituting the epitope sequence, changing one or more of the amino acids defining the epitope area of the parent protein by genetical engineering mutations of a DNA sequence encoding the parent protein, introducing the mutated DNA sequence into a suitable host, culturing said host and expressing the protein variant, and evaluating the immunogenicity of the protein variant using the parent protein as reference. The invention further relates to the protein variant and use thereof, as well as to a method for producing said protein variant. | 02-24-2011 |
| 20110110910 | Proteases for Pharmaceutical Use - The pharmaceutical use of proteases related to amino acids 1-274 of SEQ ID NO: 2, the serine protease derived from | 05-12-2011 |
| 20110136206 | Alpha-amylase variant with altered properties - The present invention relates to variants (mutants) of parent Termamyl-like alpha-amylases, which variant has alpha-amylase activity and exhibits altered properties relative to the parent alpha-amylase. | 06-09-2011 |
| 20110151522 | Glucoamylase Variants - The invention relates to a variant of a parent fungal glucoamylase, which exhibits improved thermal stability and/or increased specific activity using saccharide substrates. | 06-23-2011 |
| 20110158976 | Enzymes for pharmaceutical use - The pharmaceutical use of proteases related to a protease derived from | 06-30-2011 |
| 20110159545 | Fungamyl-like Alpha-Amylase Variants - The invention relates to a variant of a parent Fungamyl-like fungal alpha-amylase, which exhibits improved thermal stability at acidic pH suitable for, e.g., starch processes. | 06-30-2011 |
| 20110165655 | LIPOLYTIC ENZYMES - The inventors have developed a method using protein engineering to produce lipolytic enzymes having a relatively high activity for one ester bond in an amphiphilic substrate with two lipophilic groups) and a relatively low activity for the ester bond in an amphiphilic substrate with one lipophilic group, e.g. a relatively high phospholipase activity and a relatively low lysophospholipase activity. | 07-07-2011 |
