Patent application number | Description | Published |
20080248081 | METHOD OF TREATING CHRONIC DYSFUNCTION OF CARDIAC MUSCLE - Methods are described for using compositions containing platelet-rich plasma for the treatment of a variety of tissue lesions. Particularly, delivery of platelet-rich plasma to cardiac muscle for treatment of chronic dysfunction of cardiac muscle is disclosed. | 10-09-2008 |
20080248082 | METHOD OF TREATING INJURED CARDIAC TISSUE - Methods are described for using compositions containing platelet-rich plasma for the treatment of a variety of tissue lesions. Particularly, delivery of platelet-rich plasma to treat injured cardiac tissue is disclosed. | 10-09-2008 |
20080248083 | METHOD FOR TREATMENT OF TISSUE LESION - Methods are disclosed to promote vascularization of tissue in mammals using an autologous platelet-rich plasma composition. In particular, a method of treating a cardiac tissue lesion is disclosed. | 10-09-2008 |
20080248084 | METHOD OF TREATING ACUTE DYSFUNCTION OF CARDIAC MUSCLE - Methods are described for using compositions containing platelet-rich plasma for the treatment of a variety of tissue lesions. Particularly, delivery of platelet-rich plasma to treat acute dysfunction of cardiac muscle (heart attack) is disclosed. | 10-09-2008 |
20080248085 | METHOD OF TISSUE VASCULARIZATION - Methods are disclosed to promote vascularization of tissue in mammals using an autologous platelet-rich plasma composition. The methods are useful for vascularizing tissue with a compromised blood supply, particularly cardiac tissue with a compromised blood supply due to heart attack or congestive heart failure. | 10-09-2008 |
20080254093 | COMPOSITIONS AND MINIMALLY INVASIVE METHODS FOR TREATING DYSFUNCTION OF CARDIAC MUSCLE - Methods are described for using compositions containing platelet-rich plasma for the treatment of a variety of tissue lesions. Particularly, delivery of platelet-rich plasma to treat injured cardiac tissue is described. | 10-16-2008 |
20090092679 | PARTICLE/CELL SEPARATION DEVICE AND COMPOSITIONS - A particle/cell separation device is described which is particularly adapted for neutrophil depletion from a preparation of whole blood or platelet-rich plasma. Also described are blood and platelet rich plasma compositions produced using the device which are neutrophil-depleted. | 04-09-2009 |
20090297485 | COMPOSITIONS AND METHODS FOR TREATING PSYCHIATRIC AND NEURODEGENERATIVE DISORDERS - Treatment methods are disclosed for psychiatric and neurodegenerative disorders by treatment of the patient with platelet-rich plasma (PRP). PRP is administered to areas of the brain that have been identified as associated with the psychiatric or neurodegenerative disorder to replenish the dysfunctional tissue. | 12-03-2009 |
20100120144 | METHOD OF CULTURING CELLS - A blood component such as platelets is concentrated. The concentrate, such as platelet-rich plasma, is used in a cell culture medium to grow and proliferate cells. The cells may be from the same person from which the blood concentrate is obtained. The cells grown in the culture medium may be used to treat a patient which may be the same patient from which the blood was extracted and/or the cells were obtained. | 05-13-2010 |
20100135969 | METHOD OF TREATING CANCER USING PLATELET RELEASATE - Platelets are concentrated from the blood of a patient. The platelets are treated by a method such as ultrasound or agitation to obtain platelet releasate. This releasate as a whole or a component thereof is formulated into an injectable formulation which is administered to the same patient the platelets were extracted from in order to treat the patient's cancer. | 06-03-2010 |
20100233282 | DEVICE AND METHODS FOR DELIVERY OF BIOACTIVE MATERIALS TO THE RIGHT SIDE OF THE HEART - A method of delivering a bioactive composition to the right side of the heart is described. The method can be used to treat cardiac dysfunction such as myocardial infarction, arrhythmias or congestive heart failure. A dual lumen catheter is described for delivering the bioactive substance by inserting a first cannula of a dual lumen catheter into a vein to access the right ventricle. The first cannula has a first balloon which is blown up proximal to the tricuspid valve. A second cannula is then introduced which accesses the right side of the heart and coronary sinus. The bioactive substance is then delivered to the right side of the heart. The bioactive substance may include platelets and/or white blood cells at concentrations higher than what is normally found in whole blood. | 09-16-2010 |
20120070420 | COMPOSITIONS AND METHODS FOR TREATING PSYCHIATRIC AND NEURODEGENERATIVE DISORDERS - Treatment methods are disclosed for psychiatric and neurodegenerative disorders by treatment of the patient with platelet-rich plasma (PRP). PRP is administered to areas of the brain that have been identified as associated with the psychiatric or neurodegenerative disorder to replenish the dysfunctional tissue. | 03-22-2012 |
20120085651 | METHOD OF PREPARING NEUTROPHIL-DEPLETED PLATELET-RICH PLASMA - Methods of producing neutrophil-depleted platelet-rich plasma by passing a blood, platelet or platelet-rich plasma fraction through a narrow, twisted and/or charged environment to remove neutrophils and produce neutrophil-depleted platelet-rich plasma is described. The neutrophil-depleted platelet-rich plasma may be depleted in neutrophils by 75% or more and includes at least 0.5×10 | 04-12-2012 |
20120171181 | COMPOSITIONS AND MINIMALLY INVASIVE METHODS FOR TREATING CANCER - Methods are described for using compositions containing platelet-rich plasma for the treatment of a cancer in a variety of tissues. Particularly, treatment of brain cancer with platelet releasate is described. | 07-05-2012 |
20120183520 | MINIMALLY INVASIVE METHODS FOR TREATING DYSFUNCTION OF CARDIAC MUSCLE - Methods are described for using compositions containing platelet-rich plasma for the treatment of acute or chronic dysfunction of cardiac muscle. The method may employ a kit which includes a platelet-rich plasma composition and a pH adjusting agent and a catheter or syringe for delivery of the platelet-rich plasma composition to dysfunctional cardiac muscle. The kit may also include a syringe for withdrawing blood from a patient and a centrifuge device means to obtain platelet-rich plasma. | 07-19-2012 |
20130017180 | PLATELET RICH PLASMA FORMULATIONS - Compositions for platelet rich plasma (PRP) and neutrophil-depleted PRP are provided. Methods for treating ischemia damaged tissues by delivering a PRP composition, in some embodiments a neutrophil-depleted PRP composition to the damaged tissue are provided. In some variations, the compositions may be useful to treat ischemic heart disease and repair damaged cardiovascular tissue following acute myocardial infarction including congestive heart failure. In some variations, the compositions may be useful to reduce cardiac apoptosis after a heart attack. | 01-17-2013 |
20130121979 | METHOD OF TREATING CANCER USING PLATELET COMPOSITIONS - Platelets are concentrated from the blood of a patient. The platelets are unactivated or are treated by a method such as ultrasound or agitation to obtain platelet releasate. The platelets are formulated into an injectable formulation which is administered to the same patient the platelets were extracted from in order to treat the patient's cancer. | 05-16-2013 |
20140295555 | METHOD OF CULTURING CELLS - A blood component such as platelets is concentrated. The concentrate, such as platelet-rich plasma, is used in a cell culture medium to grow and proliferate cells. The cells may be from the same person from which the blood concentrate is obtained. The cells grown in the culture medium may be used to treat a patient which may be the same patient from which the blood was extracted and/or the cells were obtained. | 10-02-2014 |
20140329322 | METHOD OF DIFFERENTIATING GLIOBLASTOMA CELLS - A method of increasing differentiation of a cell line of glioblastoma cells is disclosed. A platelet-rich plasma (PRP) composition is prepared. The glioblastoma cells are cultured in the PRP composition for a time period sufficient for differentiation of the glioblastoma cells. | 11-06-2014 |
20140356893 | COMPOSITIONS AND METHODS FOR USING PLATELET-RICH PLASMA FOR DRUG DISCOVERY, CELL NUCLEAR REPROGRAMMING, PROLIFERATION OR DIFFERENTIATION - Methods are described for using compositions containing platelet-rich plasma for the treatment of a variety of tissue lesions, and the use of compositions containing platelet-rich plasma to accelerate or complete the differentiation of a cell line. Particularly, use of platelet-rich plasma in conjunction with cell differentiation. | 12-04-2014 |
20150018754 | DEVICES, COMPOSITIONS AND METHODS FOR TREATING ACUTE AND CHRONIC TISSUE DAMAGE - A device to prepare and deliver a bioactive substance such as stem cells, platelet rich plasma, and/or other bioactive compositions. The device can utilize a hallow interior or cavity to deliver bioactive substances during a surgical procedure or to an area of cartilage defect or cartilage disorder. The treated tissues can include connective tissue, cardiac muscle or tissue, spinal tissue, internal organs, skin tissue, brain tissue, vascular tissue, ocular, ear, nose, throat tissue, and/or other hematologic, endocrine or integumentary tissue. | 01-15-2015 |