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Alitalo

Annamari Alitalo, Helsinki FI

Patent application numberDescriptionPublished
20110212091MATERIALS AND METHODS FOR INHIBITING CANCER CELL INVASION - The invention provides an isolated antibody or antibody fragment thereof that binds an extracellular epitope of a fibroblast growth factor receptor-4 (FGFR4) that is expressed by mammalian cells and inhibits cancer cell invasion. Optionally, the antibody or fragment thereof binds an epitope of FGFR4 that is bound by monoclonal antibody F90-10C5, or comprises complementarity determining regions identical to those of monoclonal antibody F90-10C5. Also provided are methods of using the antibody or fragment thereof to modulate invasion, ingrowth, or metastasis of cancer cells and treat cancer in a subject. The invention additionally provides a method of identifying an antibody or antibody fragment that inhibits invasiveness.09-01-2011

Anni Alitalo, Jokioinen FI

Patent application numberDescriptionPublished
20110113840METHOD FOR TREATING AND/OR PRETREATING LIQUID MANURE OR BIOGAS PLANT REJECT FOR THE ELIMINATION OF HARMFUL SUBSTANCES, PARTICULARLY NITROGEN, PHOSPHORUS, AND ODOR MOLECULES - The invention relates to a method and an apparatus for treating and/or pre-treating liquid manure or biogas plant reject for eliminating harmful substances, particularly nitrogen, phosphorus, and odor molecules. Process tanks (05-19-2011

Kari Alitalo, Espoo FI

Patent application numberDescriptionPublished
20090087905VEGF-D polynucleotides and methods of use - VEGF-D, a new member of the PDGF family of growth factors, which among other things stimulates endothelial cell proliferation and angiogenesis and increases vascular permeability, as well as nucleotide sequences encoding it, methods for producing it, antibodies and other antagonists to it, transfected or transformed host cells for expressing it, pharmaceutical compositions containing it, and uses thereof in medical and diagnostic applications.04-02-2009
20110065636Screening and Therapy for Lymphatic Disorders Involving the FLT4 Receptor Tyrosine Kinase (VEGFR-3) - The present invention provides materials and methods for screening for and treating hereditary lymphedema in human subjects.03-17-2011

Patent applications by Kari Alitalo, Espoo FI

Kari Alitalo US

Patent application numberDescriptionPublished
20080261888Antibodies to PDGF-D - PDGF-D, a new member of the PDGF/VEGF family of growth factors, as well as the nucleotide sequence encoding it, methods for producing it, antibodies and other antagonists to it, transfected and transformed host cells expressing it, pharmaceutical compositions containing it, and uses thereof in medical and diagnostic applications, including methods for stimulating growth of a connective tissue or healing a wound in a mammal, which methods comprise administering to the mammal an effective amount of PDGF-D polypeptides or polynucleotides encoding the PDGF-D polypeptides.10-23-2008

Pekka Alitalo, Espoo FI

Patent application numberDescriptionPublished
20110102098STRUCTURE FOR REDUCING SCATTERING OF ELECTROMAGNETIC WAVES - A structure made of in certain frequency bands invisible material includes a transmission line network. The structure has a matching layer at the boundary of the material, supporting structures inside the transmission line network and that the transmission line network has been matched with the surrounding space.05-05-2011