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Alicja

Alicja Bielawska, Charleston, SC US

Patent application numberDescriptionPublished
20110071099Cationic Ceramides, And Analogs Thereof, And Their Use For Preventing Or Treating Cancer - The present invention relates to cationic ceramides, their dihydro-analogs and aromatic analogs and their derivatives, comprising a pyridinium group. Also provided are methods for making cationic ceramides comprising a pyridinium group, and their use for treating or preventing diseases associated with cell overproliferation and sphingolipid signal transduction, such as cancer, inflammation, and stenosis. The compounds are also useful as mitochondritropic agents that are localized to mitochondria carrying with them chemical cargoes, such as drugs, or signaling molecules, such as fluorophores for probing organelle structure and functions.03-24-2011
20110251197LYSOSOMOTROPIC INHIBITORS OF ACID CERAMIDASE - The presently disclosed subject matter provides compounds of the formula, formula (Ia): and pharmaceutically acceptable salts thereof, wherein R10-13-2011
20120035268SPHINGO-GUANIDINES AND THEIR USE AS INHIBITORS OF SPHINGOSINE KINASE - The presently disclosed subject matter provides compounds of the formula: (1) and pharmaceutically acceptable salts thereof, wherein R02-09-2012

Patent applications by Alicja Bielawska, Charleston, SC US

Alicja Czernicka, Koszalin PL

Patent application numberDescriptionPublished
20110017854GRINDER WITH DOUBLE FORCED MOVEMENT OF THE GRINDING MEDIUM - A grinder includes a double forced movement in which the movement of the grinding medium in the chambers of the grinder drum is forced by a vibrator device as well as by the drum itself. The combination of the vibrating movement of the rotating grinding medium, which is caused by the vibrator with the rotary movement of the grinding medium, in turn resulting from the rotation of the drum around an eccentrically shifted axis, significantly increases the centrifugal forces of the grinding medium and causes the creation of a layer of rotating grinding medium together with the grinded material inside the drum chamber, while the thickness of the layer is thereby differentiated.01-27-2011

Alicja Zaluska, Montreal CA

Patent application numberDescriptionPublished
20090053133Hydrogen generation through reactions involving sorption mechanisms - A hydrogen generating composition, capable of liberating hydrogen through a sorption mechanism in the presence of vapour or gas of a reagent which comprises a sorbent compound for sorption of the vapour or gas of the reagent and a hydrogen-releasing agent for liberating hydrogen from the reagent retained by the sorbent compound.02-26-2009

Patent applications by Alicja Zaluska, Montreal CA

Alicja Ziemienowicz, Lethbridge CA

Patent application numberDescriptionPublished
20120070900T-DNA/PROTEIN NANO-COMPLEXES FOR PLANT TRANSFORMATION - A DNA/protein nano-complex for transfecting eukaryotic cells, wherein the nano-complex comprises an expressible nucleotide molecule complexed with a VirD2 protein molecule, and a RecA protein molecule complexed with the nucleotide molecule/VirD2 protein molecule complex. The nucleotide molecule/VirD2 protein molecule/RecA protein molecule complexed may be further complexed to a cell penetrating peptide. The DNA/protein nano-complex can be used for delivering the expressible nucleotide molecule to target plant cells, in particular, monocot plant cells exemplified by wheat cells, corn cells, triticale cells, barley cells, and rye cells.03-22-2012