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Alice

Alice Asteian, Jupiter, FL US

Patent application numberDescriptionPublished
20120309757N-BIPHENYLMETHYLINDOLE MODULATORS OF PPARG - The invention provides molecular entities that bind with high affinity to PPARG (PPARγ), inhibit kinase-mediated, e.g., cdk5-mediated, phosphorylation of PPARG, but do not exert an agonistic effect on PPARG. Compounds of the invention can be used for treatment of conditions in patients wherein PPARG plays a role, such as diabetes, insulin resistance, impaired glucose tolerance, pre-diabetes, hyperglycemia, hyperinsulinemia, obesity, or inflammation. In methods of treatment of these conditions using a compound of the invention, the compound can avoid producing side effects of significant weight gain, edema, impairment of bone growth or formation, or cardiac hypertrophy, or any combination thereof, in the patient receiving the compound. Methods of preparation of the compounds, bioassay methods for evaluating compounds of the invention as non-agonistic PPARG binding compounds, and pharmaceutical compositions are also provided.12-06-2012
20120309769N-BENZYLINDOLE MODULATORS OF PPARG - The invention provides molecular entities that bind with high affinity to PPARG (PPARγ), and inhibit kinase-mediated (e.g., cdk5-mediated) phosphorylation of PPARG, but do not exert an agonistic effect on PPARG. Compounds of the invention can be used for treatment of conditions in patients wherein PPARG plays a role, such as diabetes, insulin resistance, impaired glucose tolerance, pre-diabetes, hyperglycemia, hyperinsulinemia, obesity, or inflammation. Side effects such as significant weight gain, edema, impairment of bone growth or formation, or cardiac hypertrophy, or any combination thereof, can be avoided in the mammal receiving the compound. Methods of preparation of the compounds, bioassay methods for evaluating compounds of the invention as non-agonistic PPARG binding compounds, and pharmaceutical compositions are also provided.12-06-2012

Alice Banz, Lyon FR

Patent application numberDescriptionPublished
20120009140COMPOSTITION AND THERAPEUTIC ANTI-TUMOUR VACCINE - The invention relates to a composition which induces, in a host, a cytotoxic cell response directed against cells expressing an antigen, in particular tumour cells, and which comprises red blood cells containing said antigen. These red blood cells may be in the form of an immune complex with an immunoglobulin, in particular IgG, which recognizes an epitope at the surface of the red blood cells, and/or be heat-treated or chemically treated so as to promote phagocytosis of said red blood cells by dendritic cells. As a variant, the red blood cells may be xenogenic red blood cells. The invention also relates to a therapeutic especially anti-tumour vaccine containing such a composition.01-12-2012
20120207745Composition to Induce Specific Immune Tolerance - The invention relates to a composition which induces, in a host, an immune tolerance to a peptidic or proteic active principle, said composition comprising red blood cells containing an active principle selected from the group consisting of a therapeutic peptide, polypeptide or protein, a peptidic or proteic autoantigen, peptide, polypeptide or protein inducing an allergic reaction and a transplantation peptidic or proteic antigen.08-16-2012

Alice Boussagol, Brignoud FR

Patent application numberDescriptionPublished
20090289332METHODS FOR MAKING SUBSTRATES AND SUBSTRATES FORMED THEREFROM - A method for making substrates for use in optics, electronics, or opto-electronics. The method may include transferring a seed layer onto a receiving support and depositing a useful layer onto the seed layer. The thermal expansion coefficient of the receiving support may be identical to or slightly larger than the thermal expansion coefficient of the useful layer and the thermal expansion coefficient of the seed layer may be substantially equal to the thermal expansion coefficient of the receiving support. Preferably, the nucleation layer and the intermediate support have substantially the same chemical composition.11-26-2009
20110039368METHODS FOR MAKING SUBSTRATES AND SUBSTRATES FORMED THEREFROM - A method for making substrates for use in optics, electronics, or opto-electronics. The method may include transferring a seed layer onto a receiving substrate and depositing a useful layer onto the seed layer. The thermal expansion coefficient of the receiving support may be identical to or slightly larger than the thermal expansion coefficient of the useful layer and the thermal expansion coefficient of the seed layer may be substantially equal to the thermal expansion coefficient of the receiving support. Preferably, the nucleation layer and the intermediate support have substantially the same chemical composition.02-17-2011

Patent applications by Alice Boussagol, Brignoud FR

Alice Boussagol, Villard Bonnot FR

Patent application numberDescriptionPublished
20100127353STRAIN ENGINEERED COMPOSITE SEMICONDUCTOR SUBSTRATES AND METHODS OF FORMING SAME - Composite substrates are produced that include a strained III-nitride material seed layer on a support substrate. Methods of producing the composite substrate include developing a desired lattice strain in the III-nitride material to produce a lattice parameter substantially matching a lattice parameter of a device structure to be formed on the composite substrate. The III-nitride material may be formed with a Ga polarity or a N polarity. The desired lattice strain may be developed by forming a buffer layer between the III-nitride material and a growth substrate, implanting a dopant in the III-nitride material to modify its lattice parameter, or forming the III-nitride material with a coefficient of thermal expansion (CTE) on a growth substrate with a different CTE.05-27-2010

Alice Chougnet-Sirapian, L'Hay Les Roses FR

Patent application numberDescriptionPublished
20120090842METHODS AND COMPOSITIONS FOR SUSPENDING FLUIDS IN A WELLBORE - Methods for servicing subterranean wells are disclosed. Particularly, the use of a fiber-laden fluid to separate and prevent the commingling of two stationary process fluids after placement in the borehole of a subterranean well, or in a tubular body installed in a subterranean well. Embodiments relate to the prevention of a cement plug from descending through drilling fluid to the bottom of the well. It obviates the need for mechanical devices such as packers, or special adjustment of the process fluids' rheological properties.04-19-2012

Alice Cianci, Lewisburg, WV US

Patent application numberDescriptionPublished
20120019022VEHICLE FLOOR MATS WITH REPLACEABLE ASPECTS - A durable floor mat may include a plurality of layers of replaceable covers such as paper or fabric having special coatings for the protection of the interior of the automobile. The floor mat may include loops and hooks or clasps to hold the replaceable paper in place and to aid in the ease of removal of each layer of replaceable paper.01-26-2012

Alice Dautry-Varsat, Paris FR

Patent application numberDescriptionPublished
20080213285SECRETED CHLAMYDIA POLYPEPTIDES, POLYNUCLEOTIDES CODING THEREFOR, THERAPEUTIC AND DIAGNOSTIC USES THEREOF - The present invention relates to secreted 09-04-2008

Alice Devinat, Montbeliard FR

Patent application numberDescriptionPublished
20100219368Granular Materials For Textile Treatment - A granular material for use in the treating of textile materials, comprising (i) a silicone material having at least one nitrogen containing substituent, (ii) an aluminosilicate carrier and (iii) a binder, preferably in conjunction with a surface active material. Also described is a process for preparing such granular materials, which comprises forming a water-in-oil emulsion of component (i) in conjunction with component (iii) by dispersing and agitating said components in water, followed by depositing said emulsion onto a free flowing powder form of component (ii), for example by spraying, and removing sufficient water from the product to obtain a free flowing granular material. The granules are useful in a process of treating textile materials in an aqueous medium, particularly where the textile material is denim. Preferably the granular material is added into the finishing steps of denim such as the desizing, the fading or the softening steps and helps with avoiding backstaining.09-02-2010
20110081392Shampoo Compositions - The invention relates to a granulated personal care shampoo comprising a shampoo composition comprising at least one surfactant agglomerated with a water-soluble, water-dispersible or water-insoluble solid particulate carrier. Preferably, the shampoo composition additionally contains a conditioner preferably comprising an organopolysiloxane. The granulated shampoo of the invention can dissolve readily with formation of shampoo foam in hot or cold water, and can be perceived as soft in the dry state, free flowing state and providing a pleasant feel on the skin. The granulated shampoo can be packaged in various types of biodegradable packaging such as paper (environmentally more friendly than plastic sachets) to form a stable package which do not deteriorate on storage.04-07-2011

Alice Epitropoulos, Columbus, OH US

Patent application numberDescriptionPublished
20120092620BINOCULAR GLARE TESTING DEVICES - The present invention is a glare tester attachment for use with a conventional ophthalmic instrument, comprising a pair of eye cups, both eye cups each comprising a wall partially enclosing a hollow interior chamber and having a viewing aperture defining a respective viewing line of sight axis for each eye cup, a portion of each wall being provided with a plurality of lights disposed around said line of sight axis. The invention may be incorporated into a phoropter or a hand-held device.04-19-2012

Alice Fan, Mountain View, CA US

Patent application numberDescriptionPublished
20100261224DISCOVERY AND VALIDATION OF CANCER BIOMARKERS USING A PROTEIN ANALYSIS METHODOLOGY TO ANALYZE SPECIMENS - Methods are provided for the analysis, including the serial analysis, of very small samples of tissue. The methods utilize a nanofluidic proteomic immunoassay (NIA) to quantify total and low-abundance protein isoforms in a small amount of lysate. NIA detection accurately measure oncoprotein expression and activation in limited clinical specimens, including isoforms that differ in post-translational modifications, such as phosphorylation, and the like. The NIA detection method combines isoelectric protein focusing and antibody detection in a nanofluidic system.10-14-2010

Alice Gallissian, Cachan FR

Patent application numberDescriptionPublished
20090087998DIFFUSION BARRIER LAYER AND METHOD FOR MANUFACTURING A DIFFUSION BARRIER LAYER - A diffusion barrier system for a display device comprising a layer system with at least two layers of dielectric material, wherein at least two adjacent layers of that layer system comprise the same material. A respective method for manufacturing such a diffusion barrier system in a single process chamber of a plasma deposition system has the steps of introducing a substrate to be treated in said process chamber, discretely varying in a controlled manner during deposition at least one process parameter in the process chamber, without completely interrupting such process parameter, which results in layers with different properties and finally unloading said substrate from said process.04-02-2009

Alice Glaetli, Frankfurt DE

Patent application numberDescriptionPublished
20120077676Antifungal 1,2,4-Triazolyl Derivatives Having a 5-Sulfur Substituent - The present invention relates to novel triazole compounds of the formulae I and II as defined below which carry a sulfur substituent, to agricultural compositions containing them, to their use as fungicides and to intermediate compounds used in the method of producing them.03-29-2012

Alice Glaettli, Frankfurt DE

Patent application numberDescriptionPublished
20100273651Azolylmethyloxiranes, use Thereof and Agents Containing the Same - The present invention relates to azolylmethyloxiranes of the formula I10-28-2010
20100311581Azolylmethyloxiranes, use Thereof and Agents Containing the Same - The present invention relates to triazolylmethyloxiranes of the formula I12-09-2010
20100317515Azolylmethyloxiranes, use Thereof and Agents Containing the Same - The present invention relates to triazolylmethyloxiranes of the formula I12-16-2010
20110045974Substituted Triazinylmethyl Sulfonamides - The present invention relates to triazinylmethyl sulfonamides of formula I02-24-2011
20110065577Substituted pyridin-4-yl-methyl sulfonamides as fungicides - The present invention relates to pyridin-4-ylmethyl sulfonamides of formula I03-17-2011
20110077153Substituted Heteroarylmethyl Sulfonamides - The present invention relates to heteroarylylmethyl sulfonamides of formula I03-31-2011
20110077154Substituted pyridin-4-yl-methyl sulfonamides as fungicides - The present invention relates to pyridin-4-ylmethyl sulfonamides of formula I03-31-2011
20110130283Substituted Pyridin-4-ylmethyl Sulfonamides - The present invention relates to pyridin-4-ylmethyl sulfonamides of formula I06-02-2011
20110172097Imidazole and Triazole Compounds, Their Use and Agents Containing The Same - The present invention relates to compounds of the formula I07-14-2011
20110177950Imidazole and Triazole Compounds, Their Use and Agents Containing the Same - The present invention relates to compounds of the formula I07-21-2011
20110190122Triazole and Imidazole Compounds, Use Thereof and Agents Containing Them - Compounds of the formula I08-04-2011
20120088660Antifungal 1,2,4-triazolyl Derivatives - The present invention relates to novel triazole compounds of the formulae I and II as defined below which carry a sulfur substituent, to agricultural compositions containing them, to their use as fungicides and to intermediate compounds used in the method of producing them.04-12-2012
20120088664Antifungal 1,2,4-triazolyl derivatives having a 5-sulfur subtituent - The present invention relates to novel triazole compounds of the formulae I and II as defined below which carry a sulfur substituent, to agricultural compositions containing them, to their use as fungicides and to intermediate compounds used in the method of producing them.04-12-2012
20120108422Antifungal 1,2,4-triazolyl Derivatives - The present invention relates to novel triazole compounds of the formulae I and II as defined below which carry a sulfur substituent, to agricultural compositions containing them, to their use as fungicides and to intermediate compounds used in the method of producing them.05-03-2012

Patent applications by Alice Glaettli, Frankfurt DE

Alice Glaettu, Frankfurt DE

Patent application numberDescriptionPublished
20110039693Pyrimidylmethyl Sulfonamide Compounds - The present invention relates to pyrimidin-4-ylmethyl-sulfonamides of formula (I) wherein R02-17-2011

Alice Glättli, Frankfurt DE

Patent application numberDescriptionPublished
20110039695Substituted Pyridazinylmethyl Sulfonamides - The present invention relates to pyridazinylmethyl sulfonamides of formula I02-17-2011
20110065578Substituted Pyridin-4-ylmethyl Sulfonamides - The present invention relates to the use of pyridin-4-ylmethyl sulfonamides of formula (I) (I) wherein R03-17-2011
20110183842Triazole and Imidazole Compounds, Use Thereof and Agents Containing Them - Compounds of the formula I07-28-2011

Alice Glättli, Frankfurt DE

Patent application numberDescriptionPublished
20110039695Substituted Pyridazinylmethyl Sulfonamides - The present invention relates to pyridazinylmethyl sulfonamides of formula I02-17-2011
20110065578Substituted Pyridin-4-ylmethyl Sulfonamides - The present invention relates to the use of pyridin-4-ylmethyl sulfonamides of formula (I) (I) wherein R03-17-2011
20110166020Imidazole and Triazole Compounds, Use Thereof and Agents Containing Said Compounds - The present invention relates to compounds of the formula I07-07-2011
20110172098Imidazole and Triazole Compounds, Their Use and Agents Containing the Same - The present invention relates to compounds of the formula I07-14-2011
20110172099Imidazole and Triazole Compounds, Their Use and Agents Containing the Same - The present invention relates to compounds of the formula I07-14-2011
20120088661FUNGICIDAL MIXTURES - The present invention relates to fungicidal mixtures comprising, as active components, 04-12-2012
20120088662FUNGICIDAL MIXTURES - The present invention relates to fungicidal mixtures comprising, as active components,04-12-2012
20120088665FUNGICIDAL MIXTURES - The present invention relates to fungicidal mixtures comprising, as active components, 04-12-2012

Alice Glättli, Mannheim DE

Patent application numberDescriptionPublished
20090197929Azolylmethyloxiranes, Their Use for Controlling Phytopathogenic Fungi and Agents Containing Said Compounds - The present invention relates to azolylmethyloxiranes of the general formula I08-06-2009
20090203700Azolylmethyloxiranes, Their Use for Controlling Phytopathogenic Fungi, and Compositions Comprising Them - The present invention relates to azolylmethyloxiranes of the general formula I08-13-2009
20090305887Azolylmethyloxiranes, Their Use for Controlling Phytopathogenic Fungi and Compositions Comprising Them - The present invention relates to azolylmethyloxiranes of the general formula I12-10-2009
20090325801Azolylmethyloxiranes, Use Thereof for Controlling Plant Pathogenic Fungi, and Agents Containing the Same - The present invention relates to azolylmethyloxiranes of the general formula I12-31-2009
20100087321Azolylmethyloxiranes, their use for Controlling Phytopathogenic Fungi, and Compositions Comprising Them - The present invention relates to azolylmethyloxiranes of the general formula (I) in which A stands for phenyl which is optionally substituted by one to three of the following substituents: halogen, NO04-08-2010
20100167924Azolylmethyloxiranes, Their Use for Controlling Phytopathogenic Fungi and Compositions Comprising Them - The present invention relates to azolylmethyloxiranes of the general formula I07-01-2010
20100179058Azolylmethyloxiranes, Their Use for Controlling Phytopathogenic Fungi, and Compositions Comprising Them - The present invention relates to azolylmethyloxiranes of the general formula I07-15-2010
20120220455Azolylmethyloxiranes, Their Use for Controlling Phytopathogenic Fungi and Compositions Comprising Them - The present invention relates to azolylmethyloxiranes of the general formula I08-30-2012
20120225777Azolylmethyloxiranes, Their Use for Controlling Phytopathogenic Fungi and Compositions Comprising Them - The present invention relates to azolylmethyloxiranes of the general formula I09-06-2012

Patent applications by Alice Glättli, Mannheim DE

Alice Guidot, Caluire FR

Patent application numberDescriptionPublished
20100285976METHOD FOR DETECTING RALSTONIA SOLANACEARUM RACE 3 BIOVAR 2 - The invention concerns a method for the detection of 11-11-2010

Alice He, San Rafael, CA US

Patent application numberDescriptionPublished
20100140142REMOVING UNSTABLE SULFUR COMPOUNDS FROM CRUDE OIL. - A crude oil which contains at least 0.1 wt % unstable sulfur compounds is treated in a reaction zone at low temperature to convert at least 50 wt % of the unstable sulfur compounds contained therein. The reaction and removal of sulfur from the crude may be facilitated by contacting the crude oil with a catalytic material in the presence of a stripping fluid.06-10-2010

Alice HervÉ, Paris FR

Patent application numberDescriptionPublished
20130081564DEPLOYMENT AND RECOVERY VESSEL FOR AUTONOMOUS UNDERWATER VEHICLE FOR SEISMIC SURVEY - Method and vessel for performing marine acoustic survey of a subsurface. The vessel includes a launching module configured to deploy an autonomous underwater vehicle (AUV) underwater; a recovery module configured to recover the AUV; a homing device mounted on the recovery module and configured to guide the AUV to the recovery module; and a management module connecting the launching module to the recovery module and configured to transport the AUV.04-04-2013
20130083623DEPLOYMENT AND RECOVERY OF AUTONOMOUS UNDERWATER VEHICLES FOR SEISMIC SURVEY - A system and method for performing a marine seismic survey of a subsurface. The method includes deploying under water, from a deploying vessel, an autonomous underwater vehicle (AUV); recording with seismic sensors located on the AUV seismic waves generated by an acoustic source array; instructing the AUV to surface at a certain depth relative to the water surface; recovering the AUV by bringing the AUV on a recovery vessel; and transferring recorded seismic data to the recovery vessel.04-04-2013
20130083624AUTONOMOUS UNDERWATER VEHICLE FOR MARINE SEISMIC SURVEYS - An autonomous underwater vehicle (AUV) for recording seismic signals during a marine seismic survey. The AUV includes a body having a flush shape; an intake water element located on the body and configured to take in water; at least one propulsion nozzle located on the body and configured to eject the water from the intake water element for actuating the AUV; at least one guidance nozzle located on the body and configured to eject water to change a traveling direction of the AUV; and a seismic payload located on the body of the AUV and configured to record seismic signals.04-04-2013

Alice Jaschke-Ferreri, Cerignola Fg IT

Patent application numberDescriptionPublished
20110250328Method for smoking of olives for eating - The present invention refers to a method for olive smoking, comprising the following steps: 10-13-2011

Alice Julliart, Frankfurt Am Main DE

Patent application numberDescriptionPublished
20110303876POLYMER CONTAINING ALDEHYDE GROUPS, REACTION AND CROSSLINKING OF THIS POLYMER, CROSSLINKED POLYMER, AND ELECTROLUMINESCENT DEVICE COMPRISING THIS POLYMER - The present invention relates to a polymer which comprises at least one structural unit which contains at least one aldehyde group, and to a process for the preparation of a crosslinkable or crosslinked polymer including a polymer which contains aldehyde groups. The present invention thus also relates to a crosslinkable polymer and a crosslinked polymer which is prepared by the process according to the invention, and to the use of this crosslinked polymer in electronic devices, in particular in organic electroluminescent devices, so-called OLEDs (OLED=organic light emitting device).12-15-2011
20110303877CROSSLINKABLE AND CROSSLINKED POLYMERS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF - The present invention relates to cross-linkable and cross-linked polymers and to a method for the production thereof. The invention further relates to the use of said polymers in electronic devices and to the corresponding electronic devices themselves.12-15-2011

Alice Kyriopoulos, Holzkirchen DE

Patent application numberDescriptionPublished
20100197956Vam Shell Catalyst, Method For Its Production And Use Thereof - A shell catalyst for the production of vinyl acetate monomer (VAM), comprising a porous catalyst support based on a natural sheet silicate, in particular based on an acid-treated calcined bentonite, said catalyst support being loaded with Pd and Au and being designed as a shaped body. In order to provide a shell catalyst for the production of VAM, which shell catalyst is characterized by a relatively high VAM selectivity and also a high activity, it is proposed that the catalyst support has a surface area of less than 130 m08-05-2010
20110319655CATALYST SUPPORT, PROCESS FOR ITS PREPARATION AND USE - An open-pore catalyst support comprising a material that comprises a natural sheet silicate and ZrO12-29-2011
20120289737METHOD FOR PRODUCING A METAL-CONTAINING SHELL CATALYST WITHOUT INTERMEDIATE CALCINING - A method for producing a shell catalyst which comprises, in the outer shell, one or more of the following metals: Pd, Pt, Ag and Au. Also the use of the shell catalyst produced using the method according to the invention for the production of vinyl acetate monomer, in the hydrogenation of hydrocarbons, in particular the selective hydrogenation of polyunsaturated hydrocarbon compounds, or in the oxidation of alcohols to ketones/aldehydes/carboxylic acids.11-15-2012

Patent applications by Alice Kyriopoulos, Holzkirchen DE

Alice Lavranos, Victoria AU

Patent application numberDescriptionPublished
20080220972Reduced Foam Dispersions and Formulations Therefor - A composition and method for dispersing an agriculturally active agent are disclosed. In an embodiment, a solid agrochemical formulation is disclosed. The solid agrochemical formulation comprises an agriculturally active agent, a fatty acid salt, and a chelating agent.09-11-2008

Alice Lee, Poway, CA US

Patent application numberDescriptionPublished
20120201809MULTIFUNCTIONAL ANTIBODY CONJUGATES - The present invention relates to Multifunctional Antibody Conjugates, comprising an antibody or antigen binding portion thereof, comprising at least a fragment of a light chain constant kappa region (CLκ) comprising K08-09-2012

Alice Lee-Dutra, San Diego, CA US

Patent application numberDescriptionPublished
20090099157TETRAHYDRO-PYRAZOLO-PYRIDINE THIOETHER MODULATORS OF CATHEPSIN S - Tetrahydro-pyrazolo-pyridine thioether compounds are described, which are useful as cathepsin S modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by cathepsin S activity, such as psoriasis, pain, multiple sclerosis, atherosclerosis, and rheumatoid arthritis.04-16-2009
20090111794Aryl-substituted bridged or fused diamines as modulators of leukotriene A4 hydrolase - Aryl-substituted bridged or fused diamine compounds, pharmaceutical compositions containing them, and methods of using the compounds and the pharmaceutical compositions for leukotriene A04-30-2009
20090258854Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene A4 hydrolase - Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amine compounds are described, which are useful as LTA4 hydrolase (LTA4H) modulators. Such compounds may be used in pharmaceutical compositions and methods for modulation of LTA4H and for the treatment of disease states, disorders, and conditions mediated by LTA4 hydrolase activity.10-15-2009
20090264647Benzoimidazole compounds - Benzoimidazole compounds, compositions, and methods of using them in leukocyte recruitment inhibition, in modulating H10-22-2009
20090281307Benzoimidazole compounds - Benzoimidazole compounds, compositions, and methods of using them in leukocyte recruitment inhibition, in modulating H11-12-2009
20100292208COMPOUNDS WITH TWO FUSED BICYCLIC HETEROARYL MOIETIES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE - Compounds with two fused bicyclic heteroaryl moieties and their pharmaceutical compositions, and methods of using them as leukotriene A11-18-2010
20110159563Thyazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene A4 hydrolase - Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amine compounds are described, which are useful as LTA4 hydrolase (LTA4H) modulators. Such compounds may be used in pharmaceutical compositions and methods for modulation of LTA4H and for the treatment of disease states, disorders, and conditions mediated by LTA4 hydrolase activity.06-30-2011
20110190503Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene A4 hydrolase - Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amine compounds are described, which are useful as LTA4 hydrolase (LTA4H) modulators. Such compounds may be used in pharmaceutical compositions and methods for modulation of LTA4H and for the treatment of disease states, disorders, and conditions mediated by LTA4 hydrolase activity.08-04-2011
20110257153Aryl-substituted bridged or fused diamines as modulators of leukotriene A4 hydrolase - Aryl-substituted bridged or fused diamine compounds, pharmaceutical compositions containing them, and methods of using the compounds and the pharmaceutical compositions for leukotriene A10-20-2011
20110263639Aryl-substituted bridged or fused diamines as modulators of leukotriene A4 hydrolase - Aryl-substituted bridged or fused diamine compounds, pharmaceutical compositions containing them, and methods of using the compounds and the pharmaceutical compositions for leukotriene A10-27-2011

Patent applications by Alice Lee-Dutra, San Diego, CA US

Alice Macgowan, Sheffield GB

Patent application numberDescriptionPublished
20090076032Derivatives of 18Beta-Glycyrrhetinic Acid - The present invention relates to novel derivatives of 18β-glycyrrhetinic acid and methods of synthesising the derivatives. Also included within the scope of the present invention are pharmaceutical compositions comprising the derivatives of the present invention and medical uses of the derivatives, including their use in inhibiting enzymes such as retinol dehydrogenases. The present invention also relates to methods of treating diseases, such as hyperproliferative diseases, neoplasms, cancers and photoageing.03-19-2009
20090123549Pharmaceutical Compositions - A composition comprising a pharmaceutically acceptable group (2, 4, 12, 13 or 14) metal compound for the treatment of a dermatological condition involving an abnormal decrease in the cell-to-cell adhesion between epithelial cells in the epidermal barrier.05-14-2009
20100069338PHARMACEUTICAL COMPOSITIONS - The present invention provides a composition for topical administration to the skin for treating and/or preventing a dermatological condition involving an abnormal decrease in the cell-to-cell adhesion between epithelial cells comprising a zinc salt which is at least partially soluble in water and an acid, wherein the composition has a pH less than or equal to 6. The dermatological condition is generally selected from eczema, dermatitis, atopic eczema, atopic dermatitis, non-atopic eczema, non-atopic dermatitis, seborrheic eczema, irritant contact dermatitis, allergic contact dermatitis, pruritus and sensitive skin. A preferred composition comprises zinc lactate, lactic acid and has a pH of about 4.0 to 5.0.03-18-2010
20130028986Pharmaceutical Compositions - A composition comprising a pharmaceutically acceptable group (2, 4, 12, 13 or 14) metal compound for the treatment of a dermatological condition involving an abnormal decrease in the cell-to-cell adhesion between epithelial cells in the epidermal barrier.01-31-2013

Patent applications by Alice Macgowan, Sheffield GB

Alice Machado Da Silva, Belo Horizonte BR

Patent application numberDescriptionPublished
20120021935SIGNATURE FOR THE DIAGNOSIS OF CANCER AGGRESSIVENESS AND GENETIC INSTABILITY - The present invention relates to a method for diagnosing aggressiveness and/or genetic instability of a cancer in a patient from a cancer sample of said patient, comprising: a) measuring in vitro the expression level of the POLQ gene and the expression level of a control gene in said patient cancer sample; b) calculating for said POLQ gene an expression level ratio of the expression level of POLQ to the expression of the said control gene in said patient cancer sample; c) comparing the said POLQ expression level ratio to a corresponding threshold value, and d) diagnosing cancer aggressiveness and genetic instability if the said POLQ expression level ratio is superior to a corresponding threshold values. Dedicated microarrays and kits are also described, as well as a method of selecting a suitable treatment.01-26-2012

Alice Medevielle, Pau FR

Patent application numberDescriptionPublished
20110259828Zeolite Adsorbent Having an Organic Binder - The present invention relates to an agglomerated zeolite adsorbent containing at least one polymer matrix that is greatly laden with at least one zeolite adsorbent. The invention also relates to the method for preparing such an adsorbent and to the uses thereof, particularly as an adsorbent of moisture, odors, volatile organic components, and the like.10-27-2011

Alice Meitl, Lebanon, IN US

Patent application numberDescriptionPublished
20110053966SYNERGISTIC FUNGICIDAL COMPOSITIONS CONTAINING A 5-FLUOROPYRIMIDINE DERIVATIVE FOR FUNGAL CONTROL IN CEREALS - A fungicidal composition containing a fungicidally effective amount of a) a compound of Formula IA and/or IB and (b) at least one fungicide selected from the group consisting of epoxiconazole, prothioconazole, azoxystrobin, pyraclostrobin, penthiopyrad, isopyrazam, bixafen, boscalid, prochloraz, chlorothalanil, isobutyric acid (3S,6S,7R,8R)-8-benzyl-3-[(3-isobutyryloxymethoxy-4-methoxypyridine-2-carbonyl)-amino]-6-methyl-4,9-dioxo-[1,5]dioxonan-7-yl ester, and (5,8-difluoroquinazolin-4-yl)-{2-[2-fluoro-4-(4-trifluoromethylpyridin-2-yloxy)-phenyl]-ethyl}-amine provides synergistic control of selected fungi.03-03-2011
20110082162SYNERGISTIC FUNGICIDAL COMPOSITION CONTAINING 5-FLUOROCYTOSINE FOR FUNGAL CONTROL IN CEREALS - A fungicidal composition containing a fungicidally effective amount of a) a compound of Formula I and (b) at least one fungicide selected from the group consisting of epoxiconazole, prothioconazole, azoxystrobin, pyraclostrobin, penthiopyrad, isopyrazam, bixafen, boscalid, chlorothalonil and isobutyric acid (3S,6S,7R,8R)-8-benzyl-3-[(3-isobutyryloxymethoxy-4-methoxypyridine-2-carbonyl)-amino]-6-methyl-4,9-dioxo-[1,5]dioxonan-7-yl ester provides synergistic control of selected fungi.04-07-2011

Alice Mosbach-Rosenberger, Odenthal DE

Patent application numberDescriptionPublished
20090264547VISCO-ELASTIC POLYURETHANE FOAM WITH CASTOR OIL - The present invention relates to polyether polyol compositions containing renewable raw materials, a process for preparing visco-elastic polyurethane foams using such compositions, correspondingly prepared visco-elastic foam materials, and the use thereof.10-22-2009
20110034575VISCO-ELASTIC POLYURETHANE FOAM - The invention relates to a polyether polyol composition for the preparation of polyurethane foams, comprising: 02-10-2011

Alice Muenzmay, Dormagen DE

Patent application numberDescriptionPublished
20090163618BINDERS CONTAINING NANOPARTICLES - The present invention relates to aqueous binder dispersions based on silane-modified polymeric binders and inorganic nanoparticles, a process for the preparation thereof and the use thereof for the production of high quality coatings, in particular clear lacquers.06-25-2009
20090163636SILANE-MODIFIED BINDER DISPERSIONS - The invention relates to aqueous formulations comprising silane-modified polymeric binders having a siloxane content and inorganic nanoparticles, a process for the preparation thereof and the use thereof for the preparation of aqueous coating compositions.06-25-2009
20090163648SILOXANE-CONTAINING BINDER DISPERSIONS - The invention relates to aqueous formulations comprising organic binders having a siloxane content and inorganic nanoparticles, a process for the preparation thereof and the use thereof for the preparation of aqueous coating compositions.06-25-2009

Alice Mulin, Noironte FR

Patent application numberDescriptionPublished
20110002136OPTICAL DEVICE FOR A MOTOR VEHICLE - An optical device having an optical axis (y-y) and comprising a source of light; a reflector which is associated with the source of light in order to form a light beam; and a rotary assembly which is designed to intercept the light beam, and can be rotated around an axis of rotation between first and second distinctive lighting positions. The rotary assembly comprises at least first and second shields associated respectively with the first and second lighting positions, in order to create a cut-off of the light beam. The first and second shields each comprise at least one ridge. The rotary assembly additionally is designed to permit progressive transition of the lighting between the first and second distinctive lighting positions.01-06-2011
20110216197CAMERA SET UP FOR FITTING ON BOARD A VEHICLE - A camera set up for fitting on board a motor vehicle. The camera has an electronic sensor, a multifocal, particularly bifocal optical device, an optical lens focused in long-range field, the multifocal optical device and the optical lens being set up to be able to form a first image (IM09-08-2011

Alice Munzmay, Dormagen DE

Patent application numberDescriptionPublished
20090105409AQUEOUS SECONDARY POLYMER DISPERSIONS FOR THE PRODUCTION OF COATINGS - The invention concerns aqueous secondary polymer dispersions based on special acrylate building blocks, a process for their production and their use as binders for the production of blister-free coatings.04-23-2009

Alice Pebay, Melbourne Tasmania AU

Patent application numberDescriptionPublished
20090087907Compositions and Methods for Growth of Pluripotent Cells - A method of propagating embryonic stem (ES) cells in an undifferentiated state, while maintaining both the pluripotency and the cells normal genotype is disclosed. The method comprises using recombinantly produced protein domains to attach human embryonic stem cells to the surface of a bioreactor. The ES cells are supplied with nutrients while they held in place by the recombinantly produced protein domains which may be chosen from Laminin G domain, Fibronectin domain 2, Fibronectin domain 3, Nidogen G2 domain, Nidogen G3 domain, Vitronectin somatomedin B domain, and Vitronectin somatomedin C terminal domain. Useful molecules are characterized by a high binding affinity for hES cells and a molecular weight of about 50 kDa±20%.04-02-2009

Alice Roberts, Bangkok TH

Patent application numberDescriptionPublished
20100287084APPARATUS AND METHODS FOR ANALYSING SECURITIES DATA - An apparatus for analysing securities data comprises a holdings module configured to determine, from the securities data, a value of a current holding in a security. The apparatus also comprises a disclosure determination module configured to determine, from a comparison of the value of a current holding with a rule stored in a database of disclosure rules, if the current holding is to be disclosed.11-11-2010

Alice Ruttler, Port St. Lucie, FL US

Patent application numberDescriptionPublished
20090019631Shower chair dignity mat - A waste collection device suspended below a shower chair for collecting human defecation and other bodily waste before such waste contacts a shower room floor. Due to its function, the mat further provides greater confidence and less anxiety in physically challenged and infirm individuals. The present invention is suspended by a plurality of adjustable support straps which may attach to support structures of any conventional shower chair. Support straps may include upper straps and lower straps that may be used either separately or in combination. A disposable flat collecting material may be held in place atop the upper surface of the mat by holding straps attached along opposing edges of the mat. The present invention serves to eliminate the spread of infection by preventing the shower room floor from becoming contaminated with feces and/or other bodily waste.01-22-2009

Alice Schacherl, Burgberg DE

Patent application numberDescriptionPublished
20100264342VALVE CARTRIDGE FOR A SOLENOID VALVE, AND ASSOCIATED SOLENOID VALVE - The invention relates to a valve cartridge for a solenoid valve, having a capsule, a magnetic armature that is movably guided within the capsule, a valve insert that is inserted into the capsule at a first end, and a valve body, which is pressed into a second end of the valve insert and has a main valve seat. The magnetic armature, moved by a generated magnetic force, moves a tappet guided within the valve insert. The tappet has a closing element with a sealing element which plunges into the main valve seat of the valve body in a sealing manner for carrying out a sealing function, and an associated solenoid valve. According to the invention the valve insert is configured as a one-part slotted bushing, and the valve body is configured as a bonnet-shaped bushing. The valve body configured as a bushing is pressed into a second end of the valve insert configured as a slotted bushing such that the main valve seat is disposed within the valve insert.10-21-2010

Alice Schellong, Villingen-Schwenningen DE

Patent application numberDescriptionPublished
20080306182Reactive filler for dental cements - A process' for the modification of a particulate reactive filler for a dental ionomer cement, comprising 12-11-2008

Alice Siegmann, Dusseldorf DE

Patent application numberDescriptionPublished
20100240562STABLE AQUEOUS ANTIMICROBIAL ENZYME COMPOSITIONS - The disclosure relates to an enzyme stabilization system, compositions with the enzyme stabilization system, and methods of using the enzyme composition. Preferred ratios of acid to amine are effective at stabilizing enzyme. Optional nonionic surfactants and solvents also positively contribute to enzyme stability. The compositions are useful in cleaning applications.09-23-2010
20110287994STABLE AQUEOUS ANTIMICROBIAL LIPASE ENZYME COMPOSITIONS - The disclosure relates to an enzyme stabilization system, compositions with the enzyme stabilization system, and methods of using the enzyme composition. Preferred ratios of acid to amine are effective at stabilizing enzyme. Optional nonionic surfactants and solvents also positively contribute to enzyme stability. The compositions are useful in cleaning applications.11-24-2011

Alice Sorbier, Houston, TX US

Patent application numberDescriptionPublished
20120180562LOGGING TOOL SONDE SLEEVE - A logging tool for use in a wellbore having a sensor portion for making measurements. The tool has a sleeve enclosing the sensor portion and made of a material that is transparent to the measurements being made. One or more structural elements having physical characteristics different from the material comprising the sleeve are carried on the sleeve to enhance the mechanical properties of the sleeve.07-19-2012

Alice Tarun, Shoreline, WA US

Patent application numberDescriptionPublished
20090017055PLASMODIUM LIVER STAGE ANTIGENS - The invention provides isolated liver stage Plasmodium polypeptides comprising an amino acid sequence selected from the group consisting of SEQ ID NOs: 1-48 and immunogenic derivatives thereof. The invention also provides isolated nucleic acid molecules encoding the liver stage Plasmodium polypeptides of the invention, compositions comprising one or more liver stage Plasmodium polypeptides of the invention, methods for inducing an immune response against the liver stage Plasmodium polypeptides, and methods for treating and diagnosing liver stage malaria.01-15-2009
20100166794PLASMODIUM LIVER STAGE ANTIGENS - The invention provides isolated liver stage 07-01-2010

Alice Wyrwicz, Lake Forest, IL US

Patent application numberDescriptionPublished
20110103656Quantification of Plaques in Neuroimages - A system and method for determining the location and density of plaques in a neuroimage is disclosed according to one embodiment of the invention. In some embodiments, catchment basins are identified as potential plaque areas (candidate regions) in the neuroimage. The Laplacian of each element within the catchment basins can be calculated and the highest Laplacian in the catchment basin identified as a candidate feature. The local contrast can be computed as the ratio between the local minimum of the catchment basin and the average (or some other statistic like the maximum or minimum) intensity of the neighboring watersheds can be used as another candidate feature. In some embodiments, a classifier can be used to discriminate the candidates into plaques or non-plaques, since plaques tend to have a larger Laplacian and larger local contrast than other brain structures.05-05-2011

Alice Yang, Zhoughe City TW

Patent application numberDescriptionPublished
20130095701EXTERNAL CONTACT PLUG CONNECTOR - The present disclosure relates generally to connectors such as audio and data connectors and in particular to low profile audio connectors that can be used in place of standard audio and data connectors currently used. The plug connector has a reduced plug length and thickness, an intuitive insertion orientation and a smooth, consistent feel when inserted and extracted from its corresponding receptacle connector. The plug connector may be characterized by a flat tip portion at its distal end, a base portion near its proximal end, a shell coupled at the base portion and a plurality of external contacts.04-18-2013

Alice Ylikoski, Piikkio FI

Patent application numberDescriptionPublished
20110070585INTEGRATED NUCLEIC ACID ANALYSIS - The present invention relates to an integrated method of nucleic acid analysis, and more particularly to a simplified sample pre-treatment, which renders the method more easily automated, where the sample is provided on or applied onto a solid matrix and the subsequent amplification and detection steps are performed in one single, sealed reaction vial without removing the matrix.03-24-2011

Alice Yu, La Jolla, CA US

Patent application numberDescriptionPublished
20080214442Anti-Viral Effect of an Extract of Ganoderma Lucidum - Compositions and methods for the treatment viral infections in organisms, particularly flu virus. The methods and compositions of the disclosure involve the administration to mammals and immune cells of a fucose-containing glycoprotein fraction from Reishi. An extract of 09-04-2008
20090060949Flu vaccines and methods of use thereof - This disclosure is directed, inter alia, to polynucleotides, polypeptides, vectors, cells and compositions comprising the same, and their use in affecting viral pathogenesis, in particular for influenza viral infection.03-05-2009
20100041740FLU VACCINES AND METHODS OF USE THEREOF - This disclosure is directed, inter alia, to polynucleotides, polypeptides, vectors, cells and compositions comprising the same, and their use in affecting viral pathogenesis, in particular for influenza viral infection.02-18-2010
20100136042GLOBO H AND RELATED ANTI-CANCER VACCINES WITH NOVEL GLYCOLIPID ADJUVANTS - Immunogenic compositions, cancer vaccines and methods for treating cancer are provided. Compositions comprising: (a) a glycan such as Globo H or an immunogenic fragment thereof, wherein the glycan is conjugated with a carrier protein by a linker such as para-nitrophenyl; and (b) an adjuvant comprising glycolipid capable of binding CD1d on a dendritic cell, such as an α-galactosyl-ceramide derivative, wherein the immunogenic composition induces an immune response that induces a higher relative level of IgG isotype antibodies as compared to IgM isotype antibodies, are provided. Immunogenic compositions comprising the carrier protein diphtheria toxin cross-reacting material 197 (DT-CRM197) and the adjuvant C34 are provided. Antibodies generated by immunogenic compositions disclosed herein further neutralize at least one of the antigens Globo H, stage-specific embryonic antigen-3 (SSEA-3) and stage-specific embryonic antigen-4 (SSEA-4). Therapeutics against breast cancer stem cells comprising immunogenic compositions comprising Globo H, SSEA-3 or SSEA-4 conjugated with DT-CRM197.06-03-2010

Patent applications by Alice Yu, La Jolla, CA US

Alice Yu, Taipei TW

Patent application numberDescriptionPublished
20100008954Alpha-galactosyl ceramide analogs and their use as immunotherapies - The present disclosure relates to synthetic alpha-galactosyl ceramide (α-GalCer) analogs, and their use as immunotherapies. In one aspect. a method of activating a cytokine response in a subject includes administering an effective amount of a compound to a subject, wherein the subject has an adaptive immune system that includes a population of cells, the population including at least one lymphocyte and at least one antigen-presenting cell, and wherein the compound is represented by the structure of formula 1:01-14-2010

Alice Yu US

Patent application numberDescriptionPublished
20080260774Alpha-galactosyl ceramide analogs and their use as immunotherapies - The present disclosure relates to synthetic alpha-galactosyl ceramide (α-GalCer) analogs, and their use as immunotherapies. In one aspect, a method of activating a cytokine response in a subject includes administering an effective amount of a compound to a subject, wherein the subject has an adaptive immune system that includes a population of cells, the population including at least one lymphocyte and at least one antigen-presenting cell, and wherein the compound is represented by the structure of formula 1:10-23-2008