Inventors list

Assignees list

Classification tree browser

Top 100 Inventors

Top 100 Assignees

Alexandra

Alexandra Abbadie, Le Versoud FR

Patent application number	Description	Published
20100052092	METHOD FOR FABRICATING A SEMICONDUCTOR ON INSULATOR SUBSTRATE WITH REDUCED SECCO DEFECT DENSITY - The invention relates to a method for fabricating a semiconductor on insulator substrate, in particular a silicon on insulator substrate by providing a source substrate, providing a predetermined splitting area inside the source substrate by implanting atomic species, bonding the source substrate to a handle substrate, detaching a remainder of the source substrate from the source-handle component at the predetermined splitting area to thereby transfer a device layer of the source substrate onto the handle substrate, and thinning of the device layer. To obtain semiconductor on insulator substrates with a reduced Secco defect density of less than 100 per cm	03-04-2010
20100267244	METHOD FOR TREATING GERMANIUM SURFACES AND SOLUTIONS TO BE EMPLOYED THEREIN - The present invention concerns an improved method for treating germanium surfaces in order to reveal crystal defects.	10-21-2010
20110104905	ETCHING COMPOSITION, IN PARTICULAR FOR STRAINED OR STRESSED SILICON MATERIALS, METHOD FOR CHARACTERIZING DEFECTS ON SURFACES OF SUCH MATERIALS AND PROCESS OF TREATING SUCH SURFACES WITH THE ETCHING COMPOSITION - The present invention provides a chromium-free etching composition suitable for treating various silicon-containing surfaces, including strained silicon on insulator surfaces as well as stressed silicon surfaces. The novel and inventive etching composition in accordance with the present invention includes hydrofluoric acid, nitric acid, acetic acid and an alkali iodide, preferably potassium iodide, present in an amount of 1 mmol/100 ml or more.	05-05-2011

Alexandra Amorim Salgueiro, Recife BR

Patent application number	Description	Published
20110033897	Method for the Obtainment of Hydrolytic Enzymes, Hydrolytic Method for Producing Fermentable Sugars, Additives comprising Fermentable Sugars, and Process for Producing Ethanol from Sugar Cane Bagasse - The present invention provides industrial methods involving the hydrolysis of sugar cane bagasse, including methods for producing hydrolytic enzymes, for hydrolysis of sugar cane bagasse, for the production of additives comprising fermentable sugars and the respective additives, and methods of producing ethanol. The invention methods comprised the submerged culture of	02-10-2011

Alexandra Ankersmit-Udy, Auckland NZ

Patent application number	Description	Published
20110321182	SELECTION OF ANIMALS FOR DESIRED MILK AND/OR TISSUE PROFILE - The present invention is directed to mutations in the DGAT1 gene that produce an advantageous milk, tissue and/or growth rate profile in animals carrying the mutations. The present invention is also directed to methods of identifying animals carrying the mutations in order to facilitate the selection of animals with altered milk, tissue and/or growth rate traits.	12-29-2011

Alexandra Bellettre, Salt Lake City, UT US

Patent application number	Description	Published
20100153076	IMPLANT PLANNING USING AREAS REPRESENTING CARTILAGE - Described are computer-based methods and apparatuses, including computer program products, for implant planning using areas representing cartilage. A predetermined number of control points for generating a predetermined number of areas representing cartilage are determined, wherein the predetermined number of control points are based on an implant component. Measurements corresponding to a plurality of measured cartilage points are received, wherein each cartilage point is based on an associated control point from the predetermined number of control points. A plurality of areas representing cartilage are generated, wherein each area representing cartilage is larger than and projects to an associated control point from the plurality of control points. A representation of the implant component is positioned based on a representation of a bone, the representation of the bone comprising representations of the plurality of areas representing cartilage.	06-17-2010
20100153081	IMPLANT PLANNING FOR MULTIPLE IMPLANT COMPONENTS USING CONSTRAINTS - Described are computer-based methods and apparatuses, including computer program products, for implant planning for multiple implant components using constraints. A representation of a bone and a representation of a first implant component are displayed with respect to the representation of the bone. A representation of a second implant component is displayed, wherein the first implant component and the second implant component are physically separated and not connected to each other. A positioning of the representation of the second implant component that violates at least one positioning constraint is prevented, wherein the positioning constraint is based on the representation of the first implant component.	06-17-2010

Alexandra Benchoua, Evry FR

Patent application number	Description	Published
20110229441	Method and Medium for Neural Differentiation of Pluripotent Cells - The invention relates to a culture medium comprising an inhibitor of the BMP signaling pathway; and an inhibitor of the TGF/activin/nodal signaling pathway and to a method for obtaining a population of neural precursors using said culture medium.	09-22-2011

Alexandra Blinkova, Austin, TX US

Patent application number	Description	Published
20120014993	CLOSTRIDIUM TAENIOSPORUM SPORES AND SPORE APPENDAGES AS SURFACE DISPLAY HOSTS, DRUG DELIVERY DEVICES, AND NANOBIOTECHNOLOGICAL STRUCTURES - The present disclosure relates to spore surface display compositions comprising a spore having at least one nucleic acid sequence encoding for at least one polypeptide and operable to express the polypeptide on a surface of the spore. In some embodiments, the displayed polypeptide is displayed with a spore carrier protein. In some embodiments, the spore may be derived from a	01-19-2012

Alexandra Candelas, Arlington, MA US

Patent application number	Description	Published
20100010836	METHODS AND SYSTEMS FOR COMPARING EMPLOYEE INSURANCE PLANS AMONG PEER GROUPS - The present invention is directed towards methods and systems for a benchmark based comparison of an employee insurance plan of an organization to employee insurance plans from other organizations in a peer group. The present invention enables a user to enter details about an employee insurance plan of a first organization and allows the user to compare the insurance plan to a benchmark computed from data collected from a plurality of organizations in a peer group of the first organization. The comparison report does not identify the organizations from which data is collected.	01-14-2010
20120036158	TRAVEL BOOKING METHOD AND SYSTEM - A method for searching for a travel product having one or more data elements associated therewith from a plurality of potentially suitable travel products in a system comprising a web based interface for receiving inputs from a user and from one or more sources of data, and for displaying results to a user based on the inputs; a business logic layer providing access to the sources of data in a predetermined manner, such as based on rules and preferences; and a database including data relating to the parties associated with the system; wherein the method comprises the steps of: entering one or more search parameters into the interface; launching multiple simultaneous searches based on the search criteria and one or more attribute of the travel product to the one or more sources of data to identify the potentially suitable travel products; displaying the potentially suitable travel products on the interface; selecting one or more of the potentially suitable travel products for further processing; further processing the potentially suitable travel products by normalizing the data elements associated with the potentially suitable travel products into a homogeneous display; determining a combination of data elements of the one or more potentially suitable travel products which in combination are the most suitable travel products for a customer based on customer preferences and attributes.	02-09-2012

Alexandra Capela, Mountain View, CA US

Patent application number	Description	Published
20100003749	Enriched Pancreatic Stem Cell and Progenitor Cell, Populations, and Methods For Identifying, Isolating and Enriching For Such Populations - Enriched pancreatic stem and progenitor cell populations, and methods for identifying, isolating, and enriching for pancreatic stem cells using reagents that bind to cell surface markers are provided.	01-07-2010
20100158878	TARGET POPULATIONS OF OLIGODENDROCYTE PRECURSOR CELLS AND METHODS OF MAKING AND USING SAME - This application provides for enriched target populations oligodendrocyte precursor cells (OPCs) that can differentiate into oligodendrocytes. The target OPCs may be expanded and optionally subjected to conditions to induce their differentiation into oligodendrocytes. The target OPCs and their progeny are useful for the treatment of disease associated with demyelination of central nervous system axons.	06-24-2010
20110070641	Enriched pancreatic stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations - Enriched pancreatic stem and progenitor cell populations, and methods for identifying, isolating, and enriching for pancreatic stem cells using reagents that bind to cell surface markers are provided.	03-24-2011

Alexandra Chaumonnoi, Lyon FR

Patent application number	Description	Published
20090186226	MESOSTRUCTURED ORGANIC-INORGANIC HYBRID MATERIAL - An organic/inorganic hybrid material (OIHM) that consists of elementary spherical particles is described, whereby each of said spherical particles consists of a mesostructured matrix that is based on silicon oxide and organic groups with reactive terminal groups that are linked covalently to the inorganic structure, whereby said mesostructured matrix has a pore size of between 1.5 and 30 nm and has amorphous walls with a thickness of between 1 and 20 nm. Said elementary spherical particles have a maximum diameter of 10 μm. The matrix that is based on silicon oxide can contain aluminum, titanium, zirconium and cerium. Two methods for preparation of said material are also described.	07-23-2009

Alexandra Dekoninck, Ezanville FR

Patent application number	Description	Published
20100075146	SIZING COMPOSITION FOR MINERAL FIBERS COMPRISING A PHENOLIC RESIN, AND RESULTING PRODUCTS - The present invention relates to a sizing composition for mineral fibers comprising a phenolic resin, urea, a crosslinking catalyst, and optionally additives, characterized in that the crosslinking catalyst is a mixture of ammonium sulfamate and ammonium sulfate.	03-25-2010
20100158774	TEXTURED PARTICULATE FILTER FOR CATALYTIC APPLICATIONS - Catalytic filter comprising a porous matrix consisting of an inorganic material, in the form of grains that are interconnected so as to provide cavities between them, such that the open porosity is between 30 and 60% and the median pore diameter is between 5 and 40 μm, said filter being characterized in that the grains and possibly the grain boundaries of the inorganic material are covered over at least part of their surface with a texturizing material, said texturizing consisting of irregularities having dimensions of between 10 nm and 5 microns and in that a catalytic coating at least partially coats the texturizing material and optionally, at least partially, the grains of the inorganic material.	06-24-2010
20120107500	BIOCIDAL ROOFING GRANULES, ROOFING PRODUCTS INCLUDING SUCH GRANULES, AND PROCESS FOR PREPARING SAME - Biocidal roofing granules are prepared by providing a mineral core and at least one biocidal photocatalytic metal oxide. A gel-forming inorganic coating medium is prepared and used to coat the mineral core to form a coating layer having a porous network on the mineral core, and the at least one biocidal photocatalytic metal oxide is disposed in the porous network.	05-03-2012

Alexandra Donhauser, Regensburg DE

Patent application number	Description	Published
20120085071	METHOD OF TREATING AT LEAST ONE CONTAINER IN A CONTAINER TREATMENT PLANT - A method of treating at least one container in a container treatment plant, including marking at least one container with a marking, detecting the marking of the at least one container, selecting at least one container treatment machine of a container treatment plant and/or at least one operation setting of the at least one container treatment machine of the container treatment plant based on the detected marking, and treating the at least one container based on the selection of the at least one container treatment machine and/or the at least one operation setting.	04-12-2012
20120100238	Blow Moulding Machine in a Modular Design - An apparatus for producing plastic containers includes a heating module that heats plastic preforms and a moulding module for moulding the preforms into containers. The heating module includes a first transport unit that transports the preforms during the heating and a first interface. The moulding module is downstream of the heating module in the transport direction and includes a blow moulding unit for applying a flowable medium onto the preforms for expansion thereof, a second transport unit that transports the preforms during the expansion, and a second interface. The first and second interfaces allow a mechanical connection and an electrical connection between the modules such that the moulding module may be disposed on the heating module and at least one further module integrated between the heating and moulding modules. The further module treats the preforms following the heating and prior to the moulding.	04-26-2012
20120101628	METHOD AND DEVICE FOR ASSEMBLING A HANDLING UNIT OF FILLED CONTAINERS - A method for assembling a handling unit of filled containers and a corresponding method, where the handling unit comprises different container types being different with respect to at least the height, base area, base area shape or the mechanical load capacity of the containers, and the supplied containers are arranged on a handling unit carrier. The arrangement of the containers with respect to the number and/or the position and/or the rotational position of the containers on the handling unit carrier is made in dependence on at least one of the above container parameters, and the handling units can be produced flexibly and with a high packing density.	04-26-2012

Alexandra Dubray-Demol, Donhgny Le Bio FR

Patent application number	Description	Published
20090266050	METHOD FOR CONTROLLING THE REGENERATION OF AN ELECTROSTATIC PARTICLE FILTER - A method for controlling regeneration of a particle filter by electrically heating the particle filter. According to the method, the regeneration is triggered by a calculator according to a loading level and temperature of the particle filter. The calculator simultaneously uses parameters relating to the operation of the vehicle so as to take into account the fuel consumption driven by the electrical heating of the filter.	10-29-2009

Alexandra Echegaray, Poughkeepsie, NY US

Patent application number	Description	Published
20110066989	METHOD AND SYSTEM TO AT LEAST PARTIALLY ISOLATE NETS - A method to at least partially isolate a net of a circuit design is provided and includes testing a timing characteristic of a circuit design, identifying from a result of the testing a net of the circuit design to be at least partially isolated from an adjacent net and determining a percentage of the identified net to be partially isolated.	03-17-2011

Alexandra Einerhand, Alkmaar NL

Patent application number	Description	Published
20100284972	COMPOSITIONS AND METHODS FOR MAKING ALPHA-(1,2)-BRANCHED ALPHA-(1,6) OLIGODEXTRANS - Compositions for improving the health of a subject comprise alpha-(1,2)-branched alpha-(1,6) oligodextrans, preferably with an average molecular weight between about 10 kDa and 70 kDa, between about 10% and 50% alpha-(1,2)-osidic side chains, and having at least partial indigestibility in the subject. Methods for improving the health of a subject comprise administering the composition to a subject in an amount effective to improve gut health, or to prevent or treat a gastrointestinal disorder, a cholesterol-related disorder, diabetes, or obesity. Methods for making oligodextrans having controlled size and controlled degree of branching comprise providing alpha-(1,6) oligodextrans having an average molecular weight between 0.5 and 100 kDa and introducing at least 10% alpha-(1,2)-osidic side chains onto the alpha-(1,6) oligodextrans.	11-11-2010

Alexandra Faynburd, Haifa IL

Patent application number	Description	Published
20080244694	Automated collection of forensic evidence associated with a network security incident - An automated collection of forensic evidence associated with a security incident is provided by an arrangement in which different security products called endpoints in an enterprise network are enabled for sharing security-related information over a common communication channel using an abstraction called a security assessment. A security assessment is generally configured to indicate an endpoint's understanding of a detected security incident that pertains to an object in the environment which may include users, computers, IP addresses, and website URIs (Universal Resource Identifiers). The security assessment is published by the endpoint into the channel and received by subscribing endpoints. The security assessment triggers the receiving endpoints to go into a more comprehensive or detailed mode of evidence collection. In addition, any forensic evidence having relevance to the security incident that may have already been collected prior to the detection will be marked for retention so that it is not otherwise deleted.	10-02-2008
20080244742	Detecting adversaries by correlating detected malware with web access logs - An automated arrangement for detecting adversaries is provided by examining a log that contains records of communications into and out of the enterprise network upon the detection of a security incident by which a host computer on an enterprise network becomes compromised. The log is analyzed over a window of time starting before the occurrence of the detected security incident to identify the web site URIs (Uniform Resource Identifiers) and IP (Internet Protocol) addresses (collectively “resources”) that were respectively accessed by the compromised host and/or from which traffic was received by the compromised host. When other host computers in the enterprise are detected as being compromised, a similar analysis is performed and the results of all the analyses are correlated to identify one or more resources that are common to the logged communications of all the compromised machines.	10-02-2008
20080244748	Detecting compromised computers by correlating reputation data with web access logs - Compromised host computers in an enterprise network environment comprising a plurality of security products called endpoints are detected in an automated manner by an arrangement in which a reputation service provides updates to identify resources including website URIs (Universal Resource Identifiers) and IP addresses (collectively “resources”) whose reputations have changed and represent potential threats or adversaries to the enterprise network. Responsively to the updates, a malware analyzer, which can be configured as a standalone endpoint, or incorporated into an endpoint having anti-virus/malware detection capability, or incorporated into the reputation service, will analyze logs maintained by another endpoint (typically a firewall, router, proxy server, or gateway) to identify, in a retroactive manner over some predetermined time window, those client computers in the environment that had any past communications with a resource that is newly categorized by the reputation service as malicious. Every client computer so identified is likely to be compromised.	10-02-2008

Alexandra Fede, Roma IT

Patent application number	Description	Published
20090117163	Composition and Method for the Application of Human Synthetic Pheromones Using Substance Slowly Releasing Technological Bio Capsule in form of Drops in Clothing, Underwear, Jewels and Like - The invention regards a composition for the application of human synthetic pheromones in clothing, underwear, jewels, and like, comprising at least three positive human substances, e.g. androstenone, androstenediol and/or androsterone, said composition being predisposed in said clothing, underwear, jewel or like in such way to be diffused by the user by means of a simple action. The invention regards moreover a method for the application and dispensation of said composition, use of the same composition, to clothing, underwear, jewels and like incorporating the composition and a capsule as a carrier for the same composition.	05-07-2009

Alexandra Fleur, Lakewood, CA US

Patent application number	Description	Published
20110289404	System and methods for document critique - A document application for critique a document, comprising a critique module for communication with an interface application for critique and viewing a document having a critique indicator within the document and a corresponding linked critique element in a margin of the document, is described herein.	11-24-2011

Alexandra Gladbach, Leverkusen DE

Patent application number	Description	Published
20090099247	Use of tetramic acid derivatives for controlling pets by drenching, drip application, dip application or soil injection - Compounds of the formula (I) in which A, B, G, W, X, Y and Z can have the meanings given in the description are highly suitable for controlling animal pests such as insects and/or spider mites and/or nematodes by treating the soil/growth substrate by drenching or drip application or dipping or soil injection.	04-16-2009

Alexandra Glausch, Lorrach DE

Patent application number	Description	Published
20100056481	CRYSTALLINE FORMS OF ZOLEDRONIC ACID - The invention relates to new crystalline forms of low water soluble salts of zoledronic acid, the process for preparation of these crystalline forms, compositions containing these crystalline forms, and the use of these crystalline forms in diagnostic methods or therapeutic treatment of warm-blooded animals, especially humans. The invention relates to the crystalline form of the free acid monohydrate of zoledronic acid, the process for preparation of the crystalline form of the free acid monohydrate of zoledronic acid, compositions containing the crystalline form of the free acid monohydrate of zoledronic acid, and the use of crystalline form of the free acid monohydrate of zoledronic acid in diagnostic methods or therapeutic treatment of warm-blooded animals, especially humans.	03-04-2010

Alexandra Glausch, Weil Am Rhein DE

Patent application number	Description	Published
20080254089	PHARMACEUTICAL PRODUCTS COMPRISING BISPHOSPHONATES - A pharmaceutical product comprises a container containing a bisphosphonate solution, in which at least the internal surface of the container comprises a plastic material and in which the container is heat sterilisable, and which is in the form of an infusion solution preconcentrate for administration of the bisphosphonate to a patient in need of bisphosphonate treatment.	10-16-2008
20090099232	INJECTABLE DEPOT FORMULATION COMPRISING CRYSTALS OF ILOPERIDONE - An injectable depot formulation comprising crystals having structure (I) wherein R is (FII) and the X50 value of the crystals is from 1 to 200 microns. Depot formulations containing crystals of iloperidone or its metabolites have the following advantages: (i) release of the crystals in plasma can be correlated with the size of the crystals; (ii) absorption of the crystals in plasma can be correlated with the size of the crystals; (iii) the particle size of the crystals can be controlled by crystal engineering and/or milling; and (iv) the crystals are stable upon storage, and stable to sterilization procedures, such as gamma irradiation.	04-16-2009
20110212141	INJECTABLE DEPOT FORMULATION COMPRISING CRYSTALS OF ILOPERIDONE - An injectable depot formulation comprising crystals having structure (I) wherein R is (FII) and the X50 value of the crystals is from 1 to 200 microns. Depot formulations containing crystals of iloperidone or its metabolites have the following advantages: (i) release of the crystals in plasma can be correlated with the size of the crystals; (ii) absorption of the crystals in plasma can be correlated with the size of the crystals; (iii) the particle size of the crystals can be controlled by crystal engineering and/or milling; and (iv) the crystals are stable upon storage, and stable to sterilization procedures, such as gamma irradiation.	09-01-2011
20120027818	BISPHOSPHONATE PRODUCT IN A CYCLOOLEFINIC POLYMER CONTAINER - A pharmaceutical product comprises a container containing a bisphosphonate solution, in which at least the internal surface of the container comprises a plastic material and in which the container is heat sterilisable, and which is in the form of an infusion solution preconcentrate for administration of the bisphosphonate to a patient in need of bisphosphonate treatment.	02-02-2012

Alexandra Gogonea, Pavia IT

Patent application number	Description	Published
20110196615	Processing of biological signals - A method processes a signal by storing a template sequence composed of a number N of consecutive digital samples of the signal; calculating a sequence of extended sums that includes, for each digital sample, an extended sum of absolute values of differences between N most recent digital samples and the samples of the template sequence; detecting minima of the sequence of extended sums; and estimating a period of the signal as a time interval between two consecutive minima of the sequence of extended sums. The method also estimates the noise level of the signal as a ratio between most recently-detected minimum and maximum of said sequence of extended sums. The method also generates a reduced-noise replica of the signal as a weighted average of the template sequence and of the current samples of the signal processed between two consecutive minima of said extended sum, the weighted average being calculated using weights based on the estimated noise level.	08-11-2011

Alexandra Golby, Boston, MA US

Patent application number	Description	Published
20110144476	Integrated Surgical Sampling Probe - The present invention is directed to devices for collecting tissue samples from patients. The devices create tissue fragments which are then collected by aspiration. The devices include signal emitters that allow the exact position where a biopsy sample was obtained to be determined. In addition the invention includes methods for obtaining tissue samples using these devices.	06-16-2011

Alexandra Große Böwing, Dormagen DE

Patent application number	Description	Published
20110172454	METHOD FOR PRODUCING DIPHENYLCARBONATE HAVING CATALYST COMPRISING IONIC FLUIDS - The invention relates to a method for producing diphenylcarbonate while using a catalyst composition comprising ionic fluids.	07-14-2011

Alexandra Haouy, Chauvigny FR

Patent application number	Description	Published
20110301032	Lipochito-Oligosaccharides Stimulating Arbuscular Mycorrhizal Symbiosis - The invention relates to lipochitooligosaccharides obtainable from arbuscular mycorrhizal fungi, and which are useful for stimulating arbuscular mycorrhizal symbiosis, and lateral root formation.	12-08-2011

Alexandra Huber, Dreleich DE

Alexandra Huhalov, Cambridge, MA US

Patent application number	Description	Published
20110059076	HUMAN SERUM ALBUMIN LINKERS AND CONJUGATES THEREOF - Disclosed is a human serum albumin (HSA) linker and HSA linker with binding, diagnostic, and therapeutic agents conjugated thereto. Also disclosed is a conjugate in which the HSA linker is covalently bonded to amino and carboxy terminal binding moieties that are first and second single-chain Fv molecules (scFvs). Exemplified conjugates are useful, e.g., in reducing tumor cell proliferation, e.g., for therapeutic therapeutic applications. Also disclosed are methods and kits for the diagnostic and therapeutic application of an HSA linker conjugate.	03-10-2011
20120003221	HUMAN SERUM ALBUMIN LINKERS AND CONJUGATES THEREOF - Disclosed is a human serum albumin (HSA) linker and HSA linker with binding, diagnostic, and therapeutic agents conjugated thereto. Also disclosed is a conjugate in which the HSA linker is covalently bonded to amino and carboxy terminal binding moieties that are first and second single-chain Fv molecules (scFvs). Exemplified conjugates are useful, e.g., in reducing tumor cell proliferation, e.g., for therapeutic therapeutic applications. Also disclosed are methods and kits for the diagnostic and therapeutic application of an HSA linker conjugate.	01-05-2012

Alexandra Inberg, Herzliya IL

Patent application number	Description	Published
20100133107	METHOD FOR ELECTROCHEMICAL DEPOSITION OF MONOLAYERS ON METALLIC SURFACES AND OBJECTS COATED WITH AN ORGANIC MONOLAYER - The present invention generally provides methods for the electrodeposition of organic monolayers onto the surfaces of a great variety of objects.	06-03-2010

Alexandra Jarlmark, Upplands Vasby SE

Patent application number	Description	Published
20100018818	SHOCK ABSORBER WITH HYDRAULIC FLOW DUCTS - The present invention provides a method and apparatus for a multilayer optical articles. A method comprises forming a first multilayer article with a first substrate, first adherent, and second substrate using a first holder and a second holder. The method further comprises forming a second multilayer article with the first multilayer article, a second adherent, and a third substrate using the first holder and second holder to grasp the second multilayer article. After removal of the first and second holders, the first and second adherent maintains the second multilayer article in a posture at which the second multilayer article was held by the first and second holders, wherein the first and second adherent comprise a photopolymer such that the article is capable of storing data in a reflective holographic data storage system.	01-28-2010

Alexandra Jouhanneaud, Bonneville FR

Patent application number	Description	Published
20100146650	METHOD FOR GENERATING ACTIVE ANTIBODIES AGAINST A RESISTANCE ANTIGEN, ANTIBODIES OBTAINED BY SAID METHOD AND THEIR USES - The present invention relates to the use of a milled homogenate and/or a suspension and/or a cell lysate, stemming from a tumor resistant to at least one anti-tumoral compound in order to immunize and generate in vitro an antibody, or one of its functional fragments, directed against a tumoral antigen specifically expressed at the surface of said resistant tumor and being possibly involved in the resistance of said resistant tumor. More particularly, the present invention is directed to such antibodies obtained by applying the method, such as the antibodies 1A6, 1A9, 2E11, 3C11 and 3G7, as well as to their use for treating cancer.	06-10-2010
20110020218	NOVEL ANTI CXCR4 ANTIBODIES AND THEIR USE FOR THE TREATMENT OF CANCER - The present invention relates to a novel isolated antibody, or the derived compounds or functional fragments of same, capable of binding to CXCR4 but also of inducing conformational changed of the CXCR4 homodimers and/or heterodimers.	01-27-2011
20110287451	NOVEL ANTI CXCR4 ANTIBODIES AND THEIR USE FOR THE TREATMENT OF CANCER - The present invention relates to a novel isolated antibody, or the derived compounds or functional fragments of same, capable of binding to CXCR4 but also of inducing conformational changed of the CXCR4 homodimers and/or heterodimers.	11-24-2011
20110294156	NOVEL ANTI CXCR4 ANTIBODIES AND THEIR USE FOR THE TREATMENT OF CANCER - The present invention relates to a novel isolated antibody, or the derived compounds or functional fragments of same, capable of binding to CXCR4 but also of inducing conformational changed of the CXCR4 homodimers and/or heterodimers.	12-01-2011

Alexandra Küpper, Mulheim An Der Ruhr DE

Patent application number	Description	Published
20110103943	Device for a Horizontally Split Turbomachine Housing, Guide Disc Segment and Guide Blade Carrier for a Horizontally Split Turbomachine Housing - A guide disc segment for a horizontally split turbomachine housing is provided. The guide disc segment includes a plurality of guide blades and an outer ring segment. The guide blades are fixed to the outer ring segment along an inner circumference. The outer ring segment can be rolled into or out of a guide blade carrier of the turbomachine housing. The outer ring segment has, along an outer circumference, a toothing into which a drive device engages. A tangential force can be applied to the outer ring segment by the toothing such that the guide disc segment can be driven during the rolling into or rolling out of the outer ring segment.	05-05-2011

Alexandra Kusoffsky, Lidingö SE

Patent application number	Description	Published
20080298921	COATED CUTTING TOOL INSERT - A coated cutting tool insert is disclosed particularly useful for dry and wet machining, preferably milling, in un-, low- and high alloyed steels and cast iron, with or without raw surface zones. The insert is characterized by a WC—TaC—NbC—Co cemented carbide with a W alloyed Co-binder phase and a coating including an innermost layer of TiC	12-04-2008
20080314200	FINE GRAINED CEMENTED CARBIDE WITH REFINED STRUCTURE - The present invention relates to a fine grained WC-Co cemented carbide. By adding an extremely small amount of Ti, V, Zr, Ta or Nb alone or in combinations, a grain refined cemented carbide structure with less abnormal WC-grains has been obtained.	12-25-2008
20090011267	Sintered Cemented Carbides Using Vanadium as Gradient Former - The present invention relates to a cutting tool insert for turning consisting of a cemented carbide substrate and a coating. The cemented carbide substrate comprises WC, binder phase, and vanadium containing cubic carbide phase with a binder phase enriched surface zone essentially free of cubic carbide phase. The thermal properties of the vanadium-containing cubic phase, has turned out to give excellent resistance to thermal cracking of the insert.	01-08-2009
20090242824	CEMENTED CARBIDE WITH REFINED STRUCTURE - The present invention relates to a WC—Co cemented carbide alloy. By adding an extremely small amount of Ti, V, Zr, Ta or Nb or a combination of these, a grain refined cemented carbide structure with less abnormal WC-grains has been obtained.	10-01-2009
20110183832	FINE GRAINED CEMENTED CARBIDE WITH REFINED STRUCTURE - The present invention relates to a fine grained WC-Co cemented carbide. By adding an extremely small amount of Ti, V, Zr, Ta or Nb alone or in combinations, a grain refined cemented carbide structure with less abnormal WC-grains has been obtained.	07-28-2011

Alexandra Kusoffsky, Lidingö SE

Patent application number	Description	Published
20090242824	CEMENTED CARBIDE WITH REFINED STRUCTURE - The present invention relates to a WC—Co cemented carbide alloy. By adding an extremely small amount of Ti, V, Zr, Ta or Nb or a combination of these, a grain refined cemented carbide structure with less abnormal WC-grains has been obtained.	10-01-2009

Alexandra Latypova, Rochester, NY US

Patent application number	Description	Published
20090082680	PERSONALIZED CARDIAC SAFETY RISK - A cardiac safety risk model for use in drug safety testing and/or pharmacological agent development is disclosed. The cardiac safety risk model has at least one baseline function based on at least one baseline biomarker. The cardiac safety risk model also has at least one follow-up function based on at least one follow-up biomarker. The cardiac safety risk model further has at least one overall function based on the at least one baseline function and the at least one follow-up function. A method of generating a cardiac safety risk model and a method of drug safety testing are also disclosed.	03-26-2009

Alexandra Lauric, Medford, MA US

Patent application number	Description	Published
20100284587	ANEURYSM DETECTION - An approach to automatically detecting, classifying and/or highlighting abnormal structures such as brain aneurysms is based on three-dimensional studies of the brain vessels. The approach is applicable to effectively all currently available modalities of acquisition of the cerebral vessels, including magnetic resonance angiography (MRA), computed tomography angiography (CTA), and conventional catheter-based three-dimensional rotational angiography (3DRA).	11-11-2010

Alexandra Lazetic, San Jose, CA US

Patent application number	Description	Published
20100261660	Novel co-stimulatory molecules - The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability of the polypeptides to preferentially bind a CD28 or CTLA-4 receptor at a level greater or less than the ability of human B7-1 to bind CD28 or CTLA-4, or to induce or inhibit altered level of T cell proliferation response greater compared to that generated by human B7-1. The polypeptides and polynucleotides of the invention are useful in therapeutic and prophylactic treatment methods, gene therapy applications, and vaccines.	10-14-2010

Alexandra Levich, Seattle, WA US

Patent application number	Description	Published
20110320437	Infinite Browse - An online article is enhanced by displaying, in association with the article, supplemental content that includes entities that are extracted from the article and/or entities that are related to entities that are extracted from the article. The supplemental content further includes information about each of the entities. The information about an entity may be obtained by searching for the entity in one or more searchable repositories of data. For example, the supplemental content may include, for each entity, video, image, web, and/or news search results. The supplemental content may further include information such as stock quotes, abstracts, maps, scores, and so on. The entities are selected using a variety of analyses and ranking techniques based on contextual factors such as user-specific information, time-sensitive popularity trends, grammatical features, search result quality, and so on. The entities may further be selected for purposes such as generating ad-based revenue.	12-29-2011

Alexandra Lin, Oak Hills, VA US

Patent application number	Description	Published
20100041617	Modulating mxa expression - The invention provides compositions and methods for inhibiting cell motility, metastatic cancer and viral infections in a mammal that involve increasing the activity or expression of MxA.	02-18-2010

Alexandra Lithadioti, Thermi-Thessaloniki GR

Patent application number	Description	Published
20120035374	PROCESS FOR THE PREPARATION OF FLUVASTATIN AND SALTS THEREOF - The present invention relates to an improved process for the preparation of fluvastatin or pharmaceutical acceptable salts or derivatives thereof, in particular to a one-pot process for large scale production of Fluvastatin and salts thereof in high yield and high purity and pharmaceutical preparations containing said compounds.	02-09-2012

Alexandra Manevitch, Jerusalem IL

Patent application number	Description	Published
20080317322	Identifying Ribs in Lung X-Rays - A method of detecting lung nodules in an anterior posterior x-ray radiograph comprising the steps of: generating candidate regions in image showing changes in contrast above a threshold level, and eliminating false positives by eliminating edges assignable to organs by: identifying edges; categorizing and eliminating rib edges; categorizing and eliminating lung tissue edges, and categorizing and eliminating blood vessels.	12-25-2008

Alexandra Martz, Brussels BE

Patent application number	Description	Published
20110282215	Diagnostic Tool - Diagnostic tool comprising a sheet representing a human or animal body, which body is divided into a set of zones, a first identifier being attributed to each zone, which tool also comprises, for each diagnostic to be applied, a set of indicators formed by a first indicator reproducing the first identifier attributed to the first of said zones where a person in charge of making the diagnostic must apply at least one finger of one of his or her hands and a sequence of second indicators reproducing the first identifiers attributed to the successive points attributed in zones thus identified where said person must successively apply at least one finger of his or her other hand.	11-17-2011

Alexandra Marwede, Hamburg DE

Patent application number	Description	Published
20120098455	Lighting Device Having A Plurality Of Light Sources - A lighting device (	04-26-2012

Alexandra Megally, St. Paul FR

Patent application number	Description	Published
20110274900	Multilayer Thermoplastic Sheet Materials And Thermoformed Articles Prepared Therefrom - The present invention provides multilayer sheet structures especially suited for thermoforming applications such as refrigerator cabinet and door liners comprising a surface non-foamed layer A and a surface foamed layer B having a total sheet thickness of from about 0.5 to about 20 millimeters (“mm”). Improvements in thermoformability, including cycle time reduction and polymer and energy savings, are provided. Preferably the non-foamed thermoplastic polymer surface layer (A) has a thickness of from about 0.25 to about 6 millimeters and the foamed thermoplastic polymer surface layer (B) together with any other foamed polymer layers have a total density reduction of at least about five (5) weight percent and have a total thickness greater than the total thickness of the non-foamed layer A together with any other non-foamed layers. Also provided are improvements in the thermoforming process, thermoformed articles, processes for providing thermally insulating articles and thermally insulating articles.	11-10-2011

Alexandra Metois, Athis Mons FR

Patent application number	Description	Published
20080213206	Cosmetic Composition Comprising at Least One Fatty-Chain Polylysine, Which is Intended to Improve the Surface State of Keratin Fibers - The present invention relates to a cosmetic composition comprising, in a cosmetically acceptable medium, at least one fatty-chain polylysine. The composition of the invention enables to improve the surface state of keratin fibres. The invention also relates to methods for producing fatty-chain polylysines, as well as new compounds.	09-04-2008

Alexandra Meuser, Egelsbach DE

Patent application number	Description	Published
20120060857	COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR - The present invention concerns a composition for the permanent shaping of human hair based on at least one reducing agent and further comprising a cationic polymer consisting of a copolymer of vinylpyrrolidone and vinylimidazole and a homopolymer of dimethyl diallyl ammonium chloride and process for permanent shaping human hair with the said compositions.	03-15-2012

Alexandra Meyer, Koeln DE

Patent application number	Description	Published
20110244216	THERMAL BARRIER COATING SYSTEM AND METHOD FOR THE PRODUCTION THEREOF - Disclosed is a method for producing a coating system on a component, wherein at least one coating is deposited on the component by way of atmospheric plasma spraying (APS) and at least one further coating is deposited by way of suspension plasma spraying (SPS). The coatings are particularly advantageously deposited in the sequence of APS+SPS or APS+SPS+APS or APS+SPS+erosion coating. These sequences of coatings applied in this way usually have an effect providing a first porous coating and a second porous coating disposed thereon, wherein the porosity of the second coating is greater than that of the first coating, and wherein the reflectivity is greater than that of the first coating. The increased reflectivity of the coating, particularly in the visible (VIS) and the near infrared (NIR) wavelength ranges, advantageously causes a lower thermal load for the substrate material because a smaller proportion of thermal radiation penetrates the ceramic thermal barrier coating, resulting in lower heating of the substrate (component).	10-06-2011

Alexandra Montclare, Grants Pass, OR US

Patent application number	Description	Published
20100073186	ARTICLE LOCATOR - A locator of personal articles being monitored to prevent loss or misplacement. The locator emits a location cue. The location cue may be emitted at the monitored article, or if in the form of a verbal message, may be generated at the person who is monitoring the personal article. Location cues emitted at the monitored article may be audible, visible, or olfactory. The locator may comprise two separate cooperating devices including a querying device and a cue emitting device, or may comprise only one device, such as for emitting the verbal message. The sole device may comprise a location cue emitter kept with the monitored article, such as for emitting an audible cue, a visible cue, or an olfactory cue.	03-25-2010

Alexandra Montembault, Saint-Etienne FR

Patent application number	Description	Published
20120022242	METHOD FOR PRODUCING AN ELONGATE POLYSACCHARIDE ELEMENT, IN PARTICULAR A CHITOSAN THREAD, AND POLYSACCCHARIDE THREAD OBTAINED - The invention relates to a method for producing an elongate polysaccharide element, in particular a chitosan thread, comprising an operation of extruding an extrusible solution of said polysaccharide through an extrusion die and an operation of coagulating the extruded solution. The extrusible solution is a hydroalcoholic solution containing an alcohol that does not form an azeotrope with water and which has a boiling point of more than 150° C. at atmospheric pressure. The coagulation operation includes a step of evaporating the water, preferably over the alcohol, producing a gelled extruded elongate element in the form of a mainly alcoholic gel, in particular by subjecting the extruded solution to a hot air flow. At least one operation of eliminating the alcohol contained in said gel makes it possible to obtain the elongate polysaccharide element. The chitosan thread has a crystalline structure corresponding to the anhydrous allomorph and a rupture stress of at least 150 MPa after being immersed in demineralised water for fifteen hours. The apparatus (	01-26-2012

Alexandra Nafari, Goteborg SE

Patent application number	Description	Published
20080276727	Mems Nanoindenter - In recent years there has been a growing market for more universal analysis instruments. Analysis tools such as AFM	11-13-2008

Alexandra Oussova, Ottawa CA

Patent application number	Description	Published
20100252428	HETEROGENEOUS MEMBRANE ELECTRODES - The present invention relates to planar electrochemical sensors with membrane coatings used to perform chemical analyses. The object of this invention is to provide unit-use disposable sensors of very simple and inexpensive construction, preferably with only a single membrane coating on an electrode. The invented devices are potentiometric salt-bridge reference electrodes and dissolved gas sensors constructed with a heterogeneous membrane coating of a conductor. The heterogeneous membrane, which is an intimate admixture of a hydrophobic and a hydrophilic compartment, concurrently supports constrained transport of non-volatile species through its hydrophilic compartment and rapid gas and water vapor transport through its hydrophobic compartment.	10-07-2010

Alexandra Papanikos, Berchem BE

Patent application number	Description	Published
20100029627	MTKI QUINAZOLINE DERIVATIVES - The present invention concerns the compounds of formula	02-04-2010
20100152174	MACROCYCLIC QUINAZOLE DERIVATIVES AND THEIR USE AS MTKI - The present invention concerns the compounds of formula (I), the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein Z represents NH; Y represents —C	06-17-2010

Alexandra Papanikos, Antwerpen BE

Patent application number	Description	Published
20120035171	BICYCLIC HETEROCYCLYL DERIVATIVES AS FGFR KINASE INHIBITORS FOR THERAPEUTIC USE - The invention relates to new bicyclic heterocyclyl derivatives of formula (I), to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.	02-09-2012
20120041000	IMIDAZO [1,2-A]PYRIDINE DERIVATIVES AS FGFR KINASE INHIBITORS FOR USE IN THERAPY - The invention relates to new bicyclic heterocyclyl derivatives of formula (I), to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.	02-16-2012

Alexandra Perrier-Berthelot, La Bergiere FR

Patent application number	Description	Published
20090069222	Compounds Useful as Modulators of the Proteasome Activity - The present invention relates to the use of compounds of the following general formula (I): wherein n	03-12-2009

Alexandra Radenovic, Zagreb HR

Patent application number	Description	Published
20080315175	ALIGNMENT, TRANSPORTATION AND INTEGRATION OF NANOWIRES USING OPTICAL TRAPPING - Individually trapping, transferring, and assembling high-aspect-ratio semiconductor nanowires into arbitrary structures in a fluid environment. Nanowires with diameters as small as 20 nm and aspect ratios of above 100 can be trapped and transported in three dimensions, enabling the construction of nanowire architectures which may function as active photonic devices. Moreover, nanowire structures can now be assembled in physiological environments. In one aspect, nanowires are positioned to direct light to remote samples, reducing exposure of the overall sample to intense source illumination. A tunable nanowire probe for subwavelength imaging is also described utilizing efficient second harmonic generation (SHG) whose optical frequency conversion allows implementing subwavelength microscopes.	12-25-2008

Alexandra Raulf, Bonn DE

Patent application number	Description	Published
20120117668	NUCLEIC ACID EXPRESSION CONSTRUCT AND ITS USE AS A CELL PROLIFERATION MARKER - A nucleic acid expression construct which encodes a fusion protein includes a reporter protein and a protein with a wild-type destruction signal. A sequence encoding the fusion protein is operably linked to a non-endogenous promoter. The fusion protein localizes during a cell cycle progression to subcellular structures selected from a cell cortex, a contractile ring, and a midbody.	05-10-2012

Alexandra Scherleithner, Neufeld/leitha AT

Patent application number	Description	Published
20100105895	METHOD FOR THE PRODUCTION OF HIGH-PURITY 4A, 5, 9, 10, 11, 12,-HEXAHYDRO-6H-BENZOFURO [3A, 3, 2-EF] [2] BENZAZEPINE, AND THE DERIVATIVES THEREOF - A process for the production of extremely pure galanthamine or extremely pure galanthamine derivatives, whereby a start is made from racemic bromine narwedine, which is debrominated under palladium catalysis. The working-up of the reaction mixture, which is carried out in the presence of oxygen or peroxides, is essential to the process, so that the palladium catalyst is converted into an insoluble form, a form that can be easily separated. The further reaction is carried out by reduction of enantiomerically pure narwedine to form enantiomerically pure galanthamine, whereby it is then alkylated or dealkylated, so that a corresponding substitution on the ring-nitrogen atom is achieved. By further purification, such as recrystallization, residual portions of palladium of below 5 ppm are achieved, so that the direct use as a pharmaceutical raw material is made possible.	04-29-2010

Alexandra Schmidt, Brighton GB

Patent application number	Description	Published
20090063319	SYSTEM AND METHOD FOR MONITORING ACQUISITION CHANNELS - To ensure merchant acquisition compliance, the invention enables creation of merchant selection criteria that are used to query a database of acquired merchants. A set of acquired merchants is randomly compiled based on the selection criteria and is entered into a workflow to determine compliance with a set of rules that are represented by a checklist. A checklist corresponding to the set of acquired merchants is retrieved. The set and the checklist are combined to create a case, which is assigned to a representative. The representative ensures that a merchant acquisition form for each merchant in the set complies with a checklist item. When a merchant acquisition form is found to be non-compliant, then it is either corrected by the representative (if the error is minor), or sent to an acquisition manager (when more substantive errors are found). The acquisition form is then corrected and the case is closed.	03-05-2009

Alexandra Schvent, Saint-Mande FR

Patent application number	Description	Published
20100179105	KERATIN MATERIALS MAKE-UP KIT COMPRISING REACTIVE SILICONE COMPOUNDS AND A COMPATIBLE OIL - The invention provides a make-up kit comprising at least two compositions which are packaged separately, —the kit comprising at least one compound X, at least one compound Y and at least one catalyst or one peroxide, at least one of the compounds, X or Y, being a silicone compound, —with the proviso that the compounds X and Y—and the catalyst are not simultaneously in one of said compositions, —said compounds X and Y being able to react together by a hydrosilylation reaction or by a condensation reaction, when they are brought into contact with one another, —one at least of the first and second compositions comprising at least one compatible oil, —said compounds X and Y and said compatible oil, and their respective amounts, being such that the transfer index of a deposit comprising the two compositions is less than or equal to 40 out of 100. Finally, the invention relates to a method of making-up keratin materials that involves applying the compounds X and Y and the compatible oil.	07-15-2010

Alexandra Sobeck, Portland, OR US

Patent application number	Description	Published
20080318236	Cell Free Screening Assay and Methods of Use - Methods are disclosed for identifying agents for the treatment of cancer and/or Fanconi anemia using	12-25-2008

Alexandra Staerk, Sissein CH

Patent application number	Description	Published
20110003300	RAPID STERILITY MICROASSAY - The present invention relates to a method for detecting a viable microorganism in a pharmaceutical composition comprising the steps of providing a filterable pharmaceutical composition; filtering the pharmaceutical composition to provide at least three membranes upon which the pharmaceutical composition is deposited, placing the three membranes onto solid culture media to produce at least three filtrand cultures, culturing under aerobic and anaerobic conditions and detecting a viable microorganism cell, micro-colony or colony, wherein the presence of a viable cell, micro-colony or colony on the membrane indicates the presence of a viable microorganism in the pharmaceutical composition.	01-06-2011

Alexandra Stolzing, Leipzig DE

Patent application number	Description	Published
20110236978	REPROGRAMMING CELLS TOWARD A PLURIPOTENT STATE - The present invention relates to a process for preparing reprogrammed cells, in particular for preparing pluripotent and multipotent stem cells and to the pluripotent and multipotent stem cells prepared by said processes.	09-29-2011

Alexandra Tabatchnik, La Baule FR

Patent application number	Description	Published
20100004443	LINEAR PYRIDAZINE AND PYRROLE COMPOUNDS, METHOD FOR OBTAINING THEM AND APPLICATIONS - The present invention relates to linear pyridazine compounds, and more particularly to those of these compounds which are oligopyridazine compounds, to processes for obtaining them, to their uses, and also to their reduction to pyrroles and to the uses of the pyrrole, pyridazinylpyrrole and oligopyrrole compounds obtained. The invention relates in particular to the uses as medicaments, in particular for treating pathologies such as cancer, bacterial infections or parasitic infections, and also the applications in the materials, environmental, electronics and optics field.	01-07-2010
20100298562	Pyridazine and Pyrrole Compounds, Processes For Obtaining Them and Uses - The present invention relates to nonlinear oligopyridazine compounds, to processes for obtaining them, to their uses, and also to their reduction to oligopyrroles and to the uses of the pyridazinylpyrrole and oligopyrrole compounds obtained. The invention relates in particular to the uses as medicaments, in particular for treating pathologies such as cancer, bacterial infections or parasitic infections, and also the uses in the materials, environmental, electronics and optics field.	11-25-2010

Alexandra Teleki Harsanyi, Zurich CH

Patent application number	Description	Published
20090126604	GAS PHASE PRODUCTION OF COATED TITANIA - A flame spray pyrolysis process for the preparation of ultrafine titania particles coated with a smooth, homogeneous coating of one or more metal oxides is provided. The metal oxide coating is achieved by contacting the titania particles with a metal oxide precursor downstream of the titania formation zone, after the titania particles have formed. The process provides titania particles with a high rutile content and a smooth and homogeneous coating of a metal oxide.	05-21-2009
20090252965	Surface functionalization and coating of flame-generated nanoparticles - A method for generating a chemically bonded organic functionality on the surface of particles or for condensing an organic compound onto the particle surface giving an organic coating is described. The method comprises a step of contacting a vapour containing an organic compound and a gaseous process stream containing flame-generated particles so as to react the organic compound with surface groups on the particles to give a chemically bonded organic functionality to the particle surface or so as to result in an organic coating.	10-08-2009

Alexandra Ter Halle, Lezoux FR

Patent application number	Description	Published
20100016161	PHYTOSANITARY FORMULATIONS - The invention relates to phytosanitary formulations. The phytosanitary formulations of the invention comprises at least one active ingredient and at least one alcoholic, hydro-alcoholic or aqueous extract of at least one tinctorial plant. The phytosanitary formulations of the invention can be used in the field of agriculture and horticulture, in particular.	01-21-2010

Alexandra Toboso, Seilh FR

Patent application number	Description	Published
20080210823	Control Device for Locking and Unlocking and Aircraft Door and Aircraft Door that Integrates Such a Device - A control device for locking and unlocking a door includes a handle (	09-04-2008

Alexandra Treschow, Stockolm SE

Patent application number	Description	Published
20100081194	CELLS HAVING CARDIAC GLYCOSIDE RESISTANCE - A recombinant Na+, K+-ATPase α1-subunit protein resistant to cardiac glycosides, e.g. oubain, is disclosed, as well as methods for its production and use. The resistance to cardiac glycosides are obtained by alterations in the region situated between and including the amino acids 65-133. Such recombinant protein and nucleic acid constructs expressing the same are useful as selection markers in gene therapy and research applications.	04-01-2010

Alexandra Varsanofieva, Malden, MA US

Patent application number	Description	Published
20080249749	INTERACTIVE TRUSS OBJECTS IN COMPUTER-AIDED DESIGN MODELS - Embodiments of the invention provide a computer-aided design (CAD) application configured for generating interactive truss objects in a CAD model. In one embodiment, a truss creation tool allows the user to select a truss family and the endpoints of the truss. Based on these selections, the truss creation tool generates a layout and structural members of a truss. The truss may be maintained as an interactive object within the CAD model. Thus, a user may edit the truss object, resulting in the regeneration of the truss layout and the regeneration of the structural elements of the truss.	10-09-2008

Alexandra Velty, Valencia ES

Patent application number	Description	Published
20100312018	Processes for Producing Levosandal and Levosandol - The present invention relates to processes for producing 2-ethyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-2-butenal and 2-ethyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-2-buten-1-ol using heterogeneous bifunctional catalysts with a good yield. There is provided a process for producing 2-ethyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-2-butenal by the cross-aldol condensation between campholenic aldehyde and butanal using bifunctional heterogeneous catalysts in the presence of controlled amounts of an aliphatic alcohol; and a process for producing 2-ethyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-2-buten-1-ol useful as perfume, starting from 2-ethyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-2-butenal through a MPV reduction using an acid-base bifunctional heterogeneous catalyst. Both process can be coupled in a cascade process which involves the cross-aldol condensation between campholenic aldehyde and butanal followed by the Meerwein-Ponndorf-Verley (MPV) reduction in the presence of a secondary alcohol using the same heterogeneous bifunctional catalyst for obtaining (2-ethyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-2-buten-1-ol).	12-09-2010

Alexandra Vernaleken, Eiterfeld DE

Patent application number	Description	Published
20090203621	Tripeptides that Down Regulate the Activity of Plasma Membrane transporters Including Sodium-D-Glucose Cotransporter Sglt1 - The present invention relates to the use of a regulatory protein RS1 fragment or a nucleic acid molecule encoding said regulatory protein RS1 fragment for the preparation of a pharmaceutical composition for the amelioration, prevention and/or treatment of a metabolic disease or a secondary disorder caused by a (pathological) modification of homeostasis, wherein said RS1 fragment is characterized in comprising at least the amino acid sequence Q-C-P (Glutamine-Cysteine-Proline) or derivatives thereof. Furthermore, the present invention relates to a method for the amelioration, prevention and/or treatment of a metabolic disease or a secondary disorder caused by a (pathological) modification of homeostasis, said method comprising administering to a patient in need of such amelioration, prevention and/or treatment a pharmaceutically active amount of a regulatory protein RS1 fragment or a nucleic acid molecule encoding a regulatory protein RS1 fragment, wherein said RS1 fragment is characterized in comprising at least the amino acid sequence Q-C-P (Glutamine-Cysteine-Proline) or derivatives thereof. Moreover, the present invention relates to the use of a regulatory protein RS1 fragment or a nucleic acid molecule encoding said regulatory protein RS1 fragment for the preparation of food and/or food supplements.	08-13-2009

Alexandra Zanin-Zhorov, Staten Island, NY US

Patent application number	Description	Published
20100003225	HSP60, HSP60 PEPTIDES AND T CELL VACCINES FOR IMMUNOMODULATION - The present invention provides novel uses for peptide p277—positions 437-460 of human heat shock protein 60 (HSP60)—in modulation of immune responses and inflammatory diseases. The invention further provides novel uses for HSP60 and p277 in the treatment or prevention of hepatic disorders. The invention discloses methods for treating, preventing or ameliorating the symptoms of T cell mediated inflammatory and autoimmune disorders, including hepatic disorders, which comprise administering to a subject in need thereof a composition comprising as an active ingredient an effective quantity of a molecule selected from: HSP60, p277, fragments, analogs, homologs and derivatives thereof, and nucleic acids encoding same. Also disclosed are T cell vaccination methods for treating or preventing T cell mediated disorders.	01-07-2010
20110142814	Methods for Using Protein Kinase C-Theta Inhibitors in Adoptive Immunotherapy - The present invention provides methods for reducing tumor necrosis factor activation of regulatory T cells (Tregs), restoring the activity of defective Tregs, and enhancing the function of Tregs using Protein Kinase C theta (PKC-θ) inhibitors. The enhancement in Treg function is of use in facilitating adoptive immunotherapy in the treatment of immunological disorders.	06-16-2011