| Patent application number | Description | Published |
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| 20080281352 | Lung Volume Reduction Therapy Using Crosslinked Non-Natural Polymers - One aspect of the invention relates to a hydrogel comprising a non-natural polymer comprising a plurality of pendant nucleophilic groups and a crosslinker comprising at least two pendant electrophilic groups. Another aspect of the invention relates to a hydrogel comprising a non-natural polymer comprising a plurality of pendant electrophilic groups and a crosslinker comprising at least two pendant nucleophilic groups. Yet another aspect of the invention relates to a method for reducing lung volume in a patient comprising the step of administering a hydrogel composition as described herein. Further, hydrogels of the invention may be used to achieve pleurodesis, seal brochopleural fistulas, seal an air leak in a lung, achieve hemostasis, tissue sealing (e.g., blood vessels, internal organs), or any combination thereof. In certain embodiments, the compositions and methods described herein are intended for use in the treatment of patients with emphysema. | 11-13-2008 |
| 20100040538 | Polymer Systems for Lung Volume Reduction Therapy - One aspect of the invention relates to a hydrogel comprising a polymer comprising a plurality of pendent hydroxyl groups, a crosslinker, and a sclerosing agent. Another aspect of the invention relates to a method for reducing lung volume in a patient comprising the steps of advancing into a region of a patient's lung via said patient's trachea a multi-lumen catheter lumen through a bronchoscope; and co-administering, through the multi-lumen catheter, a first mixture comprising a first amount of a polymer containing a plurality of pendent hydroxyl groups; a second mixture comprising a second amount of a crosslinker; and a third mixture comprising a third amount of a sclerosing agent; thereby forming a hydrogel in said region. In certain embodiments, the compositions and methods described herein are intended for use in the treatment of patients with emphysema of the lung. | 02-18-2010 |
| 20100185226 | Internal Clamp for Surgical Procedures - One aspect of the present invention relates to a method of occluding a vascular site in a mammal, comprising the step of introducing into the vasculature of a mammal at or proximal to a surgical site, a composition comprising at least one optionally purified inverse thermosensitive polymer, wherein said inverse thermosensitive polymer gels in said vasculature, thereby temporarily occluding a vascular site of said mammal, wherein said temporarily occluded vasculature site is kept in a substantially cylindrical shape. | 07-22-2010 |
| 20110060256 | Confinement of Kidney Stone Fragments During Lithotripsy - The present invention improves significantly the success rate of lithotripsy and reduces the risk of tissue damage, by injecting a temporary plug in front, and optionally behind a concretion (for extracorporeal lithotripsy) or behind a concretion (for intracorporeal lithotripsy). One aspect of the present invention relates to injecting an inverse thermosensitive polymer solution into a lumen, thereby preventing the migration of a concretion, or its fragments, upon extracorporeal or intracorporeal lithotripsy | 03-10-2011 |
| 20110076231 | TEMPORARY EMBOLIZATION USING INVERSE THERMOSENSITIVE POLYMERS - One aspect of the present invention relates to methods of embolizing a vascular site in a mammal comprising introducing into the vasculature of a mammal a composition comprising an inverse thermosensitive polymer, wherein said inverse thermosensitive polymer gels in said vasculature, which composition may be injected through a small catheter, and which compositions gel at or below body temperature. In certain embodiments of the methods of embolization, said composition further comprises a marker molecule, such as a dye, radiopaque, or an MRI-visible compound. | 03-31-2011 |
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| 20090095593 | COIN VALIDATION UNIT WITH CLIP FEATURE - A separate removable and replaceable coin validation unit for use in a coin-operated device has a housing and clip formations by means of which the housing is releasably held in a cavity in the coin-operated device. The coin validation unit is electrically operable and has electrical connectors which connect with complementary connectors in the cavity. The coin operated device is particularly a single bay parking meter. | 04-16-2009 |
| 20090159674 | PARKING METER AND A DEVICE THEREFOR - A single bay parking meter device is provided which accepts payment by means of a credit or debit card, an electronic purse, or coins. The device has a power supply unit, a solar power charging arrangement and power management, such that it does not need power supply cables to be installed for each meter. The parking meter device also transmits financial data to a financial institution in a wireless manner, also to avoid the need for cabling. The parking meter device is receivable in the base of a conventional single bay parking meter, such that the new parking meter device may be retrofitted to existing coin operated installed single bay parking meters, using a new cover that is also engageable with the conventional housing base. | 06-25-2009 |
| 20090183966 | METHOD AND APPARATUS FOR AUTOMATIC LOCATION-SPECIFIC CONFIGURATION MANAGEMENT OF A REMOVABLE METER UNIT - A meter apparatus and method of operating a removable meter apparatus are described. The meter apparatus includes a tag associated with unique tag identification information and configured to be permanently affixed to a location housing at a unique physical location, and includes a removable meter unit configured to mate with the location housing and receive the tag identification from the tag and report the tag identification to a data manager configured to associate an identifier of the removable meter unit with the tag identification and unique physical location, and associate configuration information for the physical location with the removable meter unit and the tag identification. The unique physical location can comprise a single-space parking location. | 07-23-2009 |
| 20090192950 | METHOD AND APPARATUS FOR OPERATING A REMOVABLE METER UNIT - A method and apparatus for operating a meter uniquely associated with a physical location are provided. The method includes monitoring a communication channel for a message from a remote device and identifying an initial message directed to the meter uniquely associated with the physical location, establishing a communication session with a data manager in response to the initial message from the remote device, receiving configuration information from the data manager, the configuration information associated with operation of the meter and uniquely associated with the physical location of the meter, and transmitting meter operating data to the data manager, wherein the meter is self-powered. | 07-30-2009 |
