| Patent application number | Description | Published |
|---|
| 20090256561 | INTEGRATED MICROCHIP INCORPORATING ATOMIC MAGNETOMETER AND MICROFLUIDIC CHANNEL FOR NMR AND MRI - An integral microfluidic device includes an alkali vapor cell and microfluidic channel, which can be used to detect magnetism for nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI). Small magnetic fields in the vicinity of the vapor cell can be measured by optically polarizing and probing the spin precession in the small magnetic field. This can then be used to detect the magnetic field of in encoded analyte in the adjacent microfluidic channel. The magnetism in the microfluidic channel can be modulated by applying an appropriate series of radio or audio frequency pulses upstream from the microfluidic chip (the remote detection modality) to yield a sensitive means of detecting NMR and MRI. | 10-15-2009 |
| 20090261826 | Low Field Magnetic Resonance Imaging - A method and system of magnetic resonance imaging does not need a large homogenous field to truncate a gradient field. Spatial information is encoded into the spin magnetization by allowing the magnetization to evolve in a non-truncated gradient field and inducing a set of 180 degree rotations prior to signal acquisition. | 10-22-2009 |
| 20100085048 | ROTATING-FRAME GRADIENT FIELDS FOR MAGNETIC RESONANCE IMAGING AND NUCLEAR MAGNETIC RESONANCE IN LOW FIELDS - A system and method for Fourier encoding a nuclear magnetic resonance (NMR) signal is disclosed. A static magnetic field B | 04-08-2010 |
| 20100102811 | NMR, MRI, and Spectroscopic MRI in Inhomogeneous Fields - A method for locally creating effectively homogeneous or “clean” magnetic field gradients (of high uniformity) for imaging (with NMR, MRI, or spectroscopic MRI) both in in-situ and ex-situ systems with high degrees of inhomogeneous field strength. The method of imaging comprises: a) providing a functional approximation of an inhomogeneous static magnetic field strength B | 04-29-2010 |
| 20100244828 | ADJUSTABLE PERMANENT MAGNET ASSEMBLY FOR NMR AND MRI - System and methods for designing and using single-sided magnet assemblies for magnetic resonance imaging (MRI) are disclosed. The single-sided magnet assemblies can include an array of permanent magnets disposed at selected positions. At least one of the permanent magnets can be configured to rotate about an axis of rotation in the range of at least +/−10 degrees and can include a magnetization having a vector component perpendicular to the axis of rotation. The single-sided magnet assemblies can further include a magnet frame that is configured to hold the permanent magnets in place while allowing the at least one of the permanent magnets to rotate about the axis of rotation. | 09-30-2010 |
| 20100264917 | DETECTION OF MAGNETIC RESONANCE SIGNALS USING A MAGNETORESISTIVE SENSOR - A method and apparatus are described wherein a micro sample of a fluidic material may be assayed without sample contamination using NMR techniques, in combination with magnetoresistive sensors. The fluidic material to be assayed is first subject to pre-polarization, in one embodiment, by passage through a magnetic field. The magnetization of the fluidic material is then subject to an encoding process, in one embodiment an rf-induced inversion by passage through an adiabatic fast-passage module. Thereafter, the changes in magnetization are detected by a pair of solid-state magnetoresistive sensors arranged in gradiometer mode. Miniaturization is afforded by the close spacing of the various modules. | 10-21-2010 |
| 20100289491 | RADIO FREQUENCY ATOMIC MAGNETOMETER - An atomic magnetometer is used to detect radio frequency magnetic fields, such as those generated in nuclear resonance experiments. The magnetometer is based on nonlinear magneto-optical rotation and pumps an atomic vapor into a quadrupole aligned state. Detection of the modulation of the polarization of a linearly polarized beam provides the radio frequency signal, which can then be processed to extract the component frequencies. | 11-18-2010 |
| 20100321017 | ULTRAHIGH TIME RESOLUTION MAGNETIC RESONANCE - Ultrahigh time resolution magnetic resonance is achieved in a flow-through device such as a microfluidic chip by imaging along the flow dimension. Position within the one-dimensional image may be related to time by the flow velocity. Thus, a time resolution corresponding to the one-dimensional image resolution is obtainable. | 12-23-2010 |
| 20110068793 | SOLVATED HYPERPOLARIZED XeNMR AND MRI SIGNAL AMPLIFICATION BY GAS EXTRACTION - The present invention provides a method and apparatus of amplifying the signal of at least one NMR spectrum and of at least one MRI of hyperpolarized xenon. In an embodiment, the invention includes dissolving the hyperpolarized xenon in a liquid via an input membrane, thereby resulting in xenon in liquid phase, encoding information in the longitudinal magnetization of the nuclear spins of the xenon in liquid phase via an encoding coil surrounding an encoding phantom coupled to an output of the input membrane and via an encoding magnet, thereby resulting in encoded xenon, extracting the encoded xenon into the gas phase from the liquid phase via an extraction membrane coupled to an output of the encoding phantom, thereby resulting in encoded xenon in the gas phase, and decoding the encoded information from the encoded xenon in gas phase via a detection coil coupled to an output of the extraction membrane. | 03-24-2011 |
| 20110160563 | DIAGNOSTIC SKIN MAPPING BY MRS, MRI AND OTHER METHODS - This invention pertains to improved methods of classifying skin types as well as improved methods for determining the appropriateness of products and evaluating methods for treating particular skin. The methods typically utilize a “skin type” database containing one or more quantitative measures (e.g., NMR data) of skin properties. The database can optionally include various qualitative measures of skin as well (e.g., Glogau scale and/or Fitzpatrick scale values). | 06-30-2011 |
