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Alexander, NC
Danny Alexander, Cary, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090155826 | Biomarkers for pre-diabetes, cardiovascular diseases, and other metabolic-syndrome related disorders and methods using the same - Biomarkers relating to insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy are provided, as well as methods for using such biomarkers as biomarkers for insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy. In addition, methods for modulating the respective disorders or conditions of a subject are also provided. Also provided are suites of small molecule entities as biomarkers for insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy. | 06-18-2009 |
| 20120003158 | Biomarkers for Inflammatory Bowel Disease and Methods Using the Same - The present invention provides various biomarkers of inflammatory bowel disease, including biomarkers for Crohn's disease and biomarkers for Ulcerative colitis. The present invention also provides various methods of using the biomarkers, including methods for diagnosis of inflammatory bowel disease, methods for distinguishing between inflammatory bowel diseases, methods of determining predisposition to inflammatory bowel disease, methods of monitoring progression/regression of inflammatory bowel disease, methods of assessing efficacy of compositions for treating inflammatory bowel disease, methods of screening compositions for activity in modulating biomarkers of inflammatory bowel disease, methods of treating inflammatory bowel disease, as well as other methods based on biomarkers of inflammatory bowel disease. | 01-05-2012 |
| 20120122981 | Biomarkers Related to Insulin Resistance and Methods using the Same - Biomarkers relating to glucose disposal rate, insulin resistance, and/or insulin resistance-related disorders are provided. Methods based on the same biomarkers are also provided. | 05-17-2012 |
| 20120208215 | Biomarkers for Pre-Diabetes, Cardiovascular Diseases, and Other Metabolic-Syndrome Related Disorders and Methods Using the Same - Biomarkers relating to insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy are provided, as well as methods for using such biomarkers as biomarkers for insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy. In addition, methods for modulating the respective disorders or conditions of a subject are also provided. Also provided are suites of small molecule entities as biomarkers for insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy. | 08-16-2012 |
Danny C. Alexander, Cary, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090093971 | System and Method for Analyzing Metabolomic Data - The present invention generates a visual display of metabolomic data compiled by a database and associated processor. More particularly, the present invention provides a database for automatically receiving a three-dimensional spectrometry data set for a group of samples. The present invention also provides a processor device for manipulating the data sets to produce plots that are directly comparable to a plurality of characteristic plots corresponding to a plurality of selected metabolites. Furthermore, the processor device may generate a visual display indicating the presence of the selected metabolites across the group of samples. Thus, the present invention enables a user to analyze a series of complex data sets in a visual display that may indicate the presence of the selected metabolites across the group of samples. Furthermore, the visual display generated by embodiments of the present invention also expedites the subjective analysis of the spectrometry data sets. | 04-09-2009 |
| 20110307180 | SYSTEM AND METHOD FOR ANALYZING METABOLOMIC DATA - The present invention generates a visual display of metabolomic data compiled by a database and associated processor. More particularly, the present invention provides a database for automatically receiving a three-dimensional spectrometry data set for a group of samples. The present invention also provides a processor device for manipulating the data sets to produce plots that are directly comparable to a plurality of characteristic plots corresponding to a plurality of selected metabolites. Furthermore, the processor device may generate a visual display indicating the presence of the selected metabolites across the group of samples. Thus, the present invention enables a user to analyze a series of complex data sets in a visual display that may indicate the presence of the selected metabolites across the group of samples. Furthermore, the visual display generated by embodiments of the present invention also expedites the subjective analysis of the spectrometry data sets. | 12-15-2011 |
Danny Carroll Alexander, Cary, NC US
Geoffrey D. Alexander, Chapel Hill, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090030706 | Method and System for Enhanced Cross-Team Change Request Management - In a data processing system having multiple logically coupled branch systems that share interdependent products and services, a system for providing enhanced cross-team change request management. In one embodiment, the system includes a consumer branch system that generates a consumer change request. A trunk system manages cross-team change requests between the branch systems in a shared database and stores a first cross-team change request that associates the consumer change request with a first provider branch system. In response to the first provider branch system determining that a supplemental consumer change request is required to address the first consumer change request, the first provider branch system generates a second cross-team change request within the trunk system. The second cross-team change request associates the supplemental consumer change request with a second provider branch system. | 01-29-2009 |
George Alexander, Durham, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090115484 | DIGITALLY CONTROLLED DELAY ELEMENT - Techniques and corresponding circuits for achieving programmable delay with linear resolution are provided. The techniques provide for incremental delay with substantially equal increments. Linear resolution may be achieved through the use of a circuit arrangement that allows current to be controlled to linearly vary effective resistance of a delay circuit, without affecting the effective capacitance. | 05-07-2009 |
| 20100030934 | Bus Termination System and Method - A memory system includes a number of integrated circuit chips coupled to a bus. Each of the integrated circuit chips has an input/output node coupled to the bus, the input/output node having a programmable on-die termination resistor. The input/output node of one of the integrated circuit chips is accessed via the bus. The programmable on-die termination resistor of each of the integrated circuit chips is independently set to a termination resistance. The termination resistance is determined by a transaction type and which of the plurality memory devices is being accessed, which information can be transmitted over a separate transmission control bus. | 02-04-2010 |
George William Alexander, Durham, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20100032820 | Stacked Memory Module - Memory modules, computing systems, and methods of manufacturing memory modules are disclosed. In one embodiment, a memory module includes a substrate having a first side and a second side opposed to the first side. A plurality of pins is disposed on the first side of the substrate. A first plurality of memory chips are arranged in a first chip layer, the first chip layer overlying the second side of the substrate. Electrical contacts of the first plurality of memory chips are electrically coupled to the pins. A second plurality of memory chips is arranged in a second chip layer, the second chip layer overlying the first chip layer. Electrical contacts of the second plurality of memory chips are electrically coupled to the pins. | 02-11-2010 |
| 20100046266 | High Speed Memory Architecture - Memory devices and memory modules are disclosed. In one embodiment, a memory device includes a semiconductor substrate having a first edge and a second edge opposed to the first edge. A plurality of memory banks is disposed at a central portion of the semiconductor substrate, each memory bank including a plurality of memory cells. A plurality of input/output contacts is disposed between the first edge and the memory banks. Delay locked loop circuitry is disposed adjacent the first edge. A plurality of address and command contacts is disposed between the second edge and the memory banks. | 02-25-2010 |
| 20100062621 | Horizontal Dual In-line Memory Modules - Horizontal dual in-line memory modules are disclosed. In one embodiment, the memory module includes a circuit board, a plurality of memory chips attached to a top surface of the circuit board, and a plurality of connector contacts disposed under a back surface of the circuit board and extending away from the memory chips, the connector contacts being electrically coupled to the memory chips, the back surface opposite the top surface of the circuit board. | 03-11-2010 |
| 20100082871 | Distributed Command and Address Bus Architecture - Distributed command and address bus architecture for memory modules and circuit boards is described. In one embodiment, a memory module includes a plurality of connector pins disposed on an edge of a circuit board, the plurality of connector pins comprising first pins coupled to a plurality of data bus lines, second pins coupled to a plurality of command and address bus lines, wherein the second pins are disposed in a first and a second region, wherein a portion of the first pins is disposed between the first and the second regions. | 04-01-2010 |
Melanie Lynn Alexander, Davidson, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20100332243 | Goal Insurance - Goal insurance is provided as a purchasable option to users who wish to have a goal tracking system monitor and enforce their goals. The user may define the goal, a reward to be given upon successful completion of the goal and penalties to be applied if the goal is not met. To avoid penalties, the user may purchase goal insurance that may be used or apply under specified circumstances. Such circumstances may include death, illness, unemployment or the like. Goal information and progress may be monitored by the goal tracking system and may further be published to one or more sites. Other users may contribute to the user's reward or send encouraging remarks. If the user does not purchase goal insurance, the predefined penalties may be applied upon expiration of a goal time period if the user has not achieved their goal. | 12-30-2010 |
Paul Alexander, Sanford, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090060152 | System and Method for Controlling a Digital Video Recorder on a Cable Network - A system and method for controlling a digital video recorder on a cable network. Signaling associated with the answering or initiation of a digital telephone call by a digital telephone subscriber is used to issue commands to a digital video recorder (DVR). A signal is generated by an MTA when the telephone is enters an “off-hook” state and sent to the DVR to initiate recording of a program being viewed by the called party. When the phone goes “on-hook”, the called party resumes watching the program from exactly where it was interrupted. The MTA may be connected directly to the VTD/DVR and the telephone state is determined by the DVR from information provided by the MTA. Alternatively, a soft switch monitors signaling from the MTA indicative of the state of the called telephone. A telephone state message comprising the telephone state information is then sent over an out-of-band channel/path to a DVR client within the VTD. The DVR client uses the telephone state information to control a DVR. | 03-05-2009 |
Randall W. Alexander, Morrisville, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20100106780 | Software Architecture for Managing a System of Heterogenous Network Processors and for Developing Portable Network Processor Applications - A method and system for developing portable network processor applications and/or managing heterogeneous network processors in a network is disclosed. The network includes host processor(s) utilizing system configuration application(s) that are network processor independent. In one aspect, the method and system include using standardized interface(s) for each network processor, using a standardized transport layer compatible with the interface(s), and providing a generic message application layer. The generic message application layer defines generic payload(s) and message type(s) for configuration communications between the network and host processors. In another aspect, the method and system include providing packet processing shell(s) and generic protocol software that is coupled with the packet processing shell(s) through standard interface(s), network processor independent, and performs operations for packet processing. The method and system also include providing a library that includes network processor specific information for performing the operations and providing block(s) for performing other network processor specific operations. | 04-29-2010 |
Tony Alexander, Charlotte, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20080243225 | Stent Removal And Repositioning Device And Associated Method - A stent removal device for removing or repositioning a stent from within a lumen is provided. The stent typically comprises at least one element arranged circumferentially about the stent. The stent removal device includes a tube positioned within the lumen proximate to the stent, wherein the tube is capable of receiving at least a portion of the stent. The stent removal device also includes a pusher positioned within the tube capable of engaging the stent and/or the element. The stent removal device further includes a hook positioned within the tube and including a hook member capable of engaging the element such that force applied to the hook causes the stent to purse string. | 10-02-2008 |
Tony D. Alexander, Charlotte, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20100305390 | THERAPEUTIC MEDICAL APPLIANCE DELIVERY AND METHOD OF USE - The present invention, in an exemplary embodiment, provides a therapeutic medical appliance, delivery device and method of use. In particular, plug therapeutic medical appliances are provided that allow for the interventional treatment of pulmonary disorders such as defects characterized by pulmonary blebs and/or diffused destructive parenchymal disease. The plug therapeutic medical appliances themselves combine many of the excellent characteristics of both silicone and metal therapeutic medical appliances while eliminating the undesirable ones. In particular, these therapeutic medical appliances are preferably self-expanding in nature and allow the predetermined differential selection of relative hardness/softness of regions of the therapeutic medical appliance to provide additional patient comfort. An exemplary embodiment also provides a family of delivery devices that facilitate flexibility, durability and/or proper installation of one or more medical appliances in a single procedure. Moreover, the preferred embodiment of the delivery device provides for the reloading of the delivery device with additional medical appliances for additional interventional procedures. | 12-02-2010 |
| 20110082392 | LUMEN-MEASURING DEVICES AND METHOD - The present invention provides a lumen measuring device and method that allows the user to calculate the exact length and diameter of a suitable interventional prosthesis as well as the height and length of stenosis during the same exploratory procedure. | 04-07-2011 |