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Alexander, MD

Peter Alexander, Woodbine, MD US

Patent application numberDescriptionPublished
20110119487System and method for encryption rekeying - Disclosed is a system and method for maintaining a secure, encrypted networking session across a communications network by dynamically replacing encryption keys during the networking session and without terminating the session. A secure control channel is embedded within the general encrypted network connection and is used to transport encrypted control messages from one network endpoint to another. In order to hide that fact that such control messages are being transferred (as opposed to general network data traffic), the control message data packets are formatted in a way to simulate the standard general network data packets.05-19-2011

Richard B. Alexander, Ellicott City, MD US

Patent application numberDescriptionPublished
20080219972Prostatic Acid Phosphatase (Pap) Materials and Methods of Use Thereof in the Prophylactic and Therapeutic Treatment of Prostate Cancer - A nucleic acid molecule comprising at least one nucleotide sequence encoding SEQ ID NO: 14, 15, 19, 41, or a sequence that is at least about 95% identical thereto; a composition comprising same and a method of administering same to induce an immune response; a polypeptide consisting of SEQ ID NO: 14, 15, 19, 41, or a sequence that is at least about 95% identical thereto; a composition comprising same and a method of administering same to induce an immune response; a composition comprising APC, which have been exposed to the polypeptide, and a method of administering same to treat prostate cancer; a composition comprising T-cells, which are specific for an epitope in a polypeptide consisting of SEQ ID NO: 14, 15, 19, or 41 and a method of administering same to treat prostate cancer; a composition comprising an anti-idiotypic antibody having an internal image of an epitope of a polypeptide consisting of SEQ ID NO: 14, 15, 19, or 41 and a method of administering same to treat prostate cancer; and an immortal B-cell line that produces an anti-idiotypic monoclonal antibody having an internal image of an epitope of a polypeptide consisting of SEQ ID NO: 14, 15, 19, or 41.09-11-2008
20080260760Prostate-Specific Antigen-Derived Mhc Class H-Restricted Peptides and Their Use in Vaccines to Treat or Prevent Prostate Cancer - The present invention relates to immunogenic peptides derived from human prostate cancer antigen (PSA-derived peptides) and their use as vaccines to treat or prevent prostate cancer. The invention is also related to dendritic cells from a patient having prostate cancer, which dendritic cells have been exposed to one or more PSA-derived peptides, and their use to treat or prevent prostate cancer in the patient. The invention is also directed to T-cells from a patient which cells are specific for PSA-activated peptide(s), and their uses to treat or prevent prostate cancer.10-23-2008

Robert M. Alexander, Mount Airy, MD US

Patent application numberDescriptionPublished
20110259666SOUND ATTENUATION CANOPY - A sound attenuation canopy for reducing levels of sound passing through an opening comprises a sound absorbing member. The sound absorbing member is comprised of a flexible sound absorbing material and has a first end, a second end and an intermediate portion extending between the first end and the second end. The first end is configured to attach to a periphery of the opening at a first location, the second end is configured to attach to a periphery of the opening at a second location and the intermediate portion is configured to be spaced apart from the opening. When the first end and the second end of the sound absorbing member are attached to the periphery of the opening, at least one side opening is at least partially defined by the intermediate portion and the perimeter of the opening, and a sound transmission flow path through open space between the opening and the side opening comprises at least one change of direction greater than 45 degrees.10-27-2011

Roger Alexander, Rockville, MD US

Patent application numberDescriptionPublished
20080285505SYSTEM AND METHOD FOR NETWORK TIMING RECOVERY IN COMMUNICATIONS NETWORKS - A system and method for determining the network timing of a communications network from a mobile station that receives signals from a plurality of base stations. An estimated location of a mobile station may be determined through any number of or combination of location technologies. Network measurements such as observed time difference values and/or a round trip time values at the mobile station or base stations in the network may be utilized. Network timing relationships may be determined as a function of the estimated location and network measurements. An estimated location of a second mobile station may be determined as a function of the network timing relationships.11-20-2008
20080287139SYSTEM AND METHOD FOR ESTIMATING THE LOCATION OF A MOBILE STATION IN COMMUNICATIONS NETWORKS - A system and method for estimating the location of a mobile station that receives signals from a plurality of base stations. An estimated location of a mobile station may be determined through any number of or combination of location technologies. Network measurements such as observed time difference values and/or a round trip time values at the mobile station or base stations in the network may be utilized. Network timing relationships may be determined as a function of the estimated location and network measurements. An estimated location of a second mobile station may be determined as a function of the network timing relationships.11-20-2008

Roger K. Alexander, Rockville, MD US

Patent application numberDescriptionPublished
20080242374METHOD AND APPARATUS FOR TRANSPARENT INVOCATION AND TRANSPORT OF ENCRYPTED POSITION LOCATION DATA - In one embodiment, the disclosure relates to a method for locating a mobile terminal in a communication network. The method includes: receiving a request data frame for locating the mobile terminal; uniquely encoding at least a portion of the request data frame (at an LCS client); determining the location of the mobile terminal (by a PDE); communicating the location information of the mobile terminal in a response data frame having an encrypted portion; and decrypting the location information of the mobile terminal (at the LCS client).10-02-2008
20110035510Methods and Apparatus Related to an Adapter Between a Premise Network and an Advanced Metering Infrastructure (AMI) Network - A system described herein can include a first node within an advanced metering infrastructure (AMI) network. The first node can be configured to be installed within a portion of a meter device. The system can also include an adapter configured to function as a second node within the AMI network. The adapter can be configured to translate a signal defined based on a platform of a premise network into a signal defined based on a platform of the AMI network. The adapter can be configured to be a meter-independent device.02-10-2011

Patent applications by Roger K. Alexander, Rockville, MD US

Stephen B. Alexander, Millersville, MD US

Patent application numberDescriptionPublished
20090041471REMODULATING CHANNEL SELECTORS FOR WDM OPTICAL COMMUNICATION SYSTEMS - The present invention provides a remodulating channel selector for a wavelength division multiplexed optical communication system. The remodulating selector receives a WDM input signal, selects a particular optical channel from the WDM signal and places the information from the selected signal onto a newly-generated optical output signal. The wavelength of the output optical signal can be the same as or different from one of the optical channels which comprises the WDM input signal. When used in a WDM optical communication system with remodulators at the transmission input, the remodulating selectors provide complete control over the interfaces with optical transmitters and receivers, permitting use with a broad range of optical equipment.02-12-2009
20100329682REMODULATING CHANNEL SELECTORS FOR WDM OPTICAL COMMUNICATION SYSTEMS - The present invention provides a remodulating channel selector for a wavelength division multiplexed optical communication system. The remodulating selector receives a WDM input signal, selects a particular optical channel from the WDM signal and places the information from the selected signal onto a newly-generated optical output signal. The wavelength of the output optical signal can be the same as or different from one of the optical channels which comprises the WDM input signal. When used in a WDM optical communication system with remodulators at the transmission input, the remodulating selectors provide complete control over the interfaces with optical transmitters and receivers, permitting use with a broad range of optical equipment.12-30-2010

Stephen B. Alexander, Annapolis, MD US

Patent application numberDescriptionPublished
20110013911HIGH-SPEED OPTICAL TRANSPONDER SYSTEMS - The present disclosure provides high-speed wavelength division multiplexing (WDM) transponders (e.g., 10 Gb/s, 40 Gb/s, 100 Gb/s, and beyond) that receive one or more optical signals and convert and/or remodulate the received optical signals onto a newly generated optical channel along with overhead processing/addition, forward error correction, and the like. In general, the transponders of the present invention include a client-side and a line-side, each with bi-directional optical transmission. The transponders provide an effective mechanism to support WDM networks that are transparent to the client-side.01-20-2011

William Alexander, Rockville, MD US

Patent application numberDescriptionPublished
20080213223Systemic viral/ligand gene delivery system and gene therapy - The present invention relates to gene transfer and gene therapy technology. More specifically, the invention provides compositions and methods for targeted virus delivery. The method utilizes a method of mixing the virus, which may be a recombinant virus which will express a protein of interest or a nucleic acid of interest, with a cell-targeting ligand, e.g., transferrin. The virus and ligand are mixed without crosslinkers or agents which would covalently bond the virus and ligand. This simple mixing causes less inactivation than chemically linking the ligand to the virus and therefore results in a more active therapeutic composition than obtained by methods which utilize crosslinking agents.09-04-2008
20090191261Antibody fragment-targeted immunoliposomes for systemic gene delivery - Nucleic acid-immunoliposome compositions useful as therapeutic agents are disclosed. These compositions preferably comprise (i) cationic liposomes, (ii) a single chain antibody fragment which binds to a transferrin receptor, and (iii) a nucleic acid encoding a wild type p53. These compositions target cells which express transferrin receptors, e.g., cancer cells. These compositions can be used therapeutically to treat persons or animals who have cancer, e.g., head and neck cancer, breast cancer or prostate cancer.07-30-2009

Patent applications by William Alexander, Rockville, MD US