Patent application number | Description | Published |
20090016935 | Coating formulations including polyphosphazene polyelectrolytes and biologically active agents and asperities coated with such formulations - A formulation for coating asperities, such as microprojections or microneedles, which comprises at least one polyphosphazene polyelectrolyte and at least one biologically active agent. Such formulation provides for improved loading and improved homogeneity of the at least one biologically active agent on the microprojections or microneedles. | 01-15-2009 |
20090017210 | METHODS AND SYSTEMS FOR COATING A MICRONEEDLE WITH A DOSAGE OF A BIOLOGICALLY ACTIVE COMPOUND - Methodologies and systems are disclosed for coating one or more microneedles, particularly in a microneedle array, for administering a predetermined dosage of biologically active compound through the skin to a recipient. The microneedles of the array are each immersed into at least one reservoir of a fluid liquid formulation of the biologically active compound wherein the at least one reservoir receives a metered predetermined amount of the formulation that corresponds to the dosage to be coated on each microneedle. The microneedles are immersed into the at least one reservoir one or more times to consume the entire amount of formulation in the at least one reservoir such the consumed amount forms the coating comprising one or more layers comprising the predetermined dose on each microneedle. Various embodiments are disclosed for immersing the microneedles one needle at a time, one or more times into the reservoir, or in an array into corresponding reservoirs in one or more repetitive immersions. The reservoirs may be repetitively filled to the predetermined amount to produce the desired single dosage on a microneedle. | 01-15-2009 |
20090041810 | Immunostimulating polyphosphazene compounds for intradermal immunization - Disclosed are intradermally administered products and methods for producing an immune response in a human or in an animal comprising an antigen and a polyphosphazene polyelectrolyte adjuvant in an amount effective to elicit an immune response in the human or in the animal against said antigen. | 02-12-2009 |
20100322891 | Immuniostimulating polyphosphazene compounds - Polyphosphazene polymers having immunomodulating activity, and the biomedical use of such polyphosphazene polymers, in conjunction with an antigen or an immunogen are disclosed. | 12-23-2010 |
20110020421 | Biodegradable polyphosphazenes containing pyrrolidone side groups - Biodegradable polyphosphazene polymers containing pyrrolidone side groups, and the biomedical use of such polyphosphazene polymers are disclosed. | 01-27-2011 |
20130136758 | Immunostimulating Polyphosphazene Compounds - Polyphosphazene polymers having immunomodulating activity, and the biomedical use of such polyphosphazene polymers, in conjunction with an antigen or an immunogen are disclosed. | 05-30-2013 |
20140314707 | Immunostimulating Polyphosphazene Compounds - Polyphosphazene polymers having immunomodulating activity, and the biomedical use of such polyphosphazene polymers, in conjunction with an antigen or an immunogen are disclosed. | 10-23-2014 |
20150238600 | Immunostimulating Polyphosphazene Compounds - Polyphosphazene polymers having immunomodulating activity, and the biomedical use of such polyphosphazene polymers, in conjunction with an antigen or an immunogen are disclosed. | 08-27-2015 |