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Ales

Ales Charvat, Göttingen DE

Patent application numberDescriptionPublished
20090321627METHOD AND SYSTEM FOR HIGH THROUGHPUT MASS ANALYSIS - The invention relates to a test method, especially for mass spectroscopy of biomolecules, including the following steps: one or several samples (12-31-2009

Ales Charvat, Gottingen DE

Patent application numberDescriptionPublished
20080296799Methods and Devices for the Production of Solid Filaments in a Vacuum Chamber - Disclosed are methods for producing a solid filament from a liquid in a vacuum chamber, comprising the following steps: a gas is liquefied in a heat exchanger apparatus to produce the liquid; and the liquid is delivered into the vacuum chamber via a supply duct and through a nozzle. Liquefying of the gas in the heat exchanger apparatus encompasses adjusting a p-T operating point of the liquid at which the liquid is transformed into the solid aggregate state and forms a collimated and stable jet after being discharged from the nozzle into the vacuum chamber. Also disclosed are nozzle arrangements for producing solid filaments in a vacuum.12-04-2008
20090321627METHOD AND SYSTEM FOR HIGH THROUGHPUT MASS ANALYSIS - The invention relates to a test method, especially for mass spectroscopy of biomolecules, including the following steps: one or several samples (12-31-2009
20100230586METHOD AND APPARATUS FOR PROVIDING A SAMPLE FOR A SUBSEQUENT ANALYSIS - The invention relates to a method and an apparatus for providing a sample for a subsequent analysis of the sample, particularly for analyzing biomolecules, comprising the following steps: generating a free micro liquid jet in an environment having a predetermined pressure, wherein the micro liquid jet contains a carrier liquid and the sample to be analyzed, and dispersing the micro liquid jet into droplets containing the sample, wherein the environment surrounding the micro liquid jet is a gaseous environment in which the pressure is above vacuum conditions.09-16-2010
20110116604Plasma-based generation of X-radiation with a sheet-shaped target material - Methods for the plasma-based generation of X-radiation are described with the steps: provision of a target material (05-19-2011

Patent applications by Ales Charvat, Gottingen DE

Ales Charvat, Goettingen DE

Patent application numberDescriptionPublished
20080308644Nozzle Assembly - The invention relates to a nozzle assembly (12-18-2008

Ales Franc, Brno CZ

Patent application numberDescriptionPublished
20090175947PHARMACEUTICAL COMPOSITION FOR INJECTIONAL PARTICULARLY TARGETED LOCAL ADMINISTRATION - The invention relates to a pharmaceutical composition for injectional, in particular targeted local administration, characterized in that it comprises a sterile suspension of platinum complex of general formula (I), wherein A and A′ independently of one another are an NH07-09-2009
20090209641PHARMACEUTICAL COMPOSITION FOR ADMINISTRATION BY INJECTION - A pharmaceutical composition for administration by injection, comprising a mixture of platinum complex of general formula (I), wherein A and A′ independently of one another are an NH08-20-2009
20100010083PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION - An oral pharmaceutical composition characterized in that it consists of a suspension of a platinum complex of general formula I, wherein A and A′ independently of one another are an NH01-14-2010

Patent applications by Ales Franc, Brno CZ

Ales Halama, Pardubice CZ

Patent application numberDescriptionPublished
20100174083METHOD FOR THE PREPARATION OF MONTELUKAST - A method of preparation of Montelukast of formula (I) by reaction of the compound of formula (III) and a compound of formula (IX), characterized in that the reaction is carried out in the presence of a base, an inert solvent and a component increasing selectivity of the process, especially of a polyether of general formula (XIII), wherein R stands for hydrogen or an alkyl and the value of n varies from 1 to 40, polyethyleneglycol of general formula (XIV), wherein n=1 to 40 or a crown-ether of formulae (XV), (XVI) or (XVII).07-08-2010
20100267958METHOD FOR ISOLATION AND PURIFICATION OF MONTELUKAST - A method of isolation of Montelukast of formula I from reaction mixtures, comprising conversion of the crude sub-stance to well-crystallizing salts with primary amines in the environment of at least one organic solvent and acetonitrile, followed by re-crystallization of these salts with simultaneous removal of chemical impurities and use of the chemically pure salts of Montelukast with primary amines for direct transformation to the pharmaceutically useful amorphous form of Montelukast sodium of formula II.10-21-2010
20110034692SPECIFIC IMPURITIES OF MONTELUKAST - The subject-matter of the invention consists in a method of removing specific impurities of montelukast of formula (I), which occur due to chemical instability of the target substance and also contaminate the substance in the preparation process. Further, methods of isolation of specific impurities of montelukast defined by formulae (V-A), (IV-A), (XIIIa-A), (XIIIb-A) and analytic methods used for the control of the production of montelukast in the pharmaceutical quality.02-10-2011

Patent applications by Ales Halama, Pardubice CZ

Ales Kostak, Porici Nad Sazavou CZ

Patent application numberDescriptionPublished
20090230749SWING-OUT JOYSTICK - An operator control assembly includes an operator manipulable control, and a first armrest movably coupling the operator manipulable control to a frame of a construction vehicle. The first armrest is movable from a first vertical orientation to a second vertical orientation and from a first horizontal orientation to a second horizontal orientation, such that when the armrest is in the second horizontal orientation, the armrest is positioned with in a footprint of the vehicle.09-17-2009

Ales Krouzecký, Letkov CZ

Patent application numberDescriptionPublished
20100114003Method to suppress blood coagulation in the circuit of the device substituting the kidney function and apparatus realizing this method - A method and device for reducing blood coagulation in the circuit of a device for substitution of the kidney function wherein, prior to the input in the device for substituting the kidney function, the blood which left the patient's body is cooled down to a temperature in the range 10° C. to 30° C. and, as the blood passes the device for substitution of the kidney function, that blood is warmed up to a temperature at least near to the body temperature and then it is returned in the patient's body.05-06-2010

Ales Krouzecký, Letkov CZ

Patent application numberDescriptionPublished
20100114003Method to suppress blood coagulation in the circuit of the device substituting the kidney function and apparatus realizing this method - A method and device for reducing blood coagulation in the circuit of a device for substitution of the kidney function wherein, prior to the input in the device for substituting the kidney function, the blood which left the patient's body is cooled down to a temperature in the range 10° C. to 30° C. and, as the blood passes the device for substitution of the kidney function, that blood is warmed up to a temperature at least near to the body temperature and then it is returned in the patient's body.05-06-2010

Ales Machara, Brevnov CZ

Patent application numberDescriptionPublished
20120046465Processes for the Preparation of Morphinane and Morphinone Compounds - The present application describes processes for the synthesis of morphinane and morphinone compounds, useful as pharmaceutical agents. Also included are novel intermediates useful in the preparation of these compounds. The process comprises quaternization of oripavine to provide a mixture of the R- and S-isomeric (at the nitrogen) quaternary salts. The R-isomer is readily isolated and converted to various N-(R)-morphinane and N-(S)-morphinone compounds. The R-isomer, S-isomer or a mixture of R- and S-isomers may be demethylated and converted to various morphinane and morphinone compounds.02-23-2012

Ales Machara, Brenov CZ

Patent application numberDescriptionPublished
20110313163Methods for One-Pot N-Demethylation/N-Functionalization of Morphine and Tropane Alkaloids - The present invention provides a method for the N-demethylation and N-functionalization of an N-methylated heterocycle such as a morphine alkaloid or tropane alkaloid. The method comprises reacting the heterocycle with an functionalization agent in the presence of a transition metal catalyst in air or in the presence of an oxidant.12-22-2011

Ales Markytan, Regensburg DE

Patent application numberDescriptionPublished
20120057341Lantern, and Method for Retrofitting a Lantern - A lantern is disclosed that includes a lamp post (03-08-2012
20120087133Lighting Device - An illumination device, comprising a basic body (04-12-2012

Ales Medek, Winchester, MA US

Patent application numberDescriptionPublished
20110123449Solid Forms of N-(4-(7-Azabicyclo[2.2.1]Heptan-7-yl)-2-Trifluoromethyl)Phenyl)-4-Oxo-5-(- Trifluoromethyl)-1,4-Dihydroquinoline-3-Carboxamide - The present invention relates to substantially crystalline and solid state forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide (Form A-HCl, Form B, Form B-HCl, or any combination of these forms), pharmaceutical compositions thereof, and methods of treatment therewith.05-26-2011
20110230519SOLID FORMS OF N-[2,4-BIS(1,1-DIMETHYLETHYL)-5-HYDROXYPHENYL]-1,4-DIHYDRO-4-OXOQUINOLINE- -3-CARBOXAMIDE - The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.09-22-2011

Ales Mrhar, Ljubljana SL

Patent application numberDescriptionPublished
20100183714GASTRORESISTANT PHARMACEUTICAL DOSAGE FORM COMPRISING N-(2-(2- PHTHALIMIDOETHOXY)-ACETYL)-L-ALANYL-D-GLUTAMIC ACID (LK-423) - The present invention relates to the pharmaceutical dosage forms which enable a controlled and/or a targeted delivery of an active substance to the selected regions of gastrointestinal tract of humans or animals. The pharmaceutical dosage forms preferably comprises the active substance N-(2(2-phthalimidoethoxy)-acetyl)-L-alanyl-D-glutamic acid (designated as LK 423). Methods of treatment of chronic inflammatory diseases of gastrointestinal tract of humans and/or animals by using the pharmaceutical dosage forms of the invention are disclosed.07-22-2010

Ales Mrzel, Ljubljana SI

Patent application numberDescriptionPublished
20100129285Process for the Synthesis of Nanotubes and Fullerene-Like Nanostructures of Transition Metal Dichalcogenides, Quasi One-Dimensional Structures of Transition Metals and Oxides of Transition Metals - The object of the invention is a process for the synthesis of nanotubes of transition metal dichalcogenides, of fullerene-like nanostructures of transition metal dichalcogenides, of nanotubes of transition metal dichalcogenides, filled with fullerene-like nanostructures of transition metal dichalcogenides, of quasi one-dimensional structures (nanowires, microwires and ribbons) of transition metal oxides and of quasi one-dimensional structures of transition metal dichalcogenides, consisting of fine crystallites of transition metal dichalcogenides. The process is characterized in that the synthesis occurs by the chemical transformation of quasi one-dimensional compounds with a sub-micron diameter, described by the formula M05-27-2010

Patent applications by Ales Mrzel, Ljubljana SI

Ales Podgornik, Sentvid Pri Sticni SI

Patent application numberDescriptionPublished
20120103886SAMPLE DISTRIBUTION DEVICE FOR DISTRIBUTION OF SAMPLES IN LIQUID CHROMATOGRAPHS - A sample distribution device for distribution of samples in liquid chromatographs comprises a sample supply channel arranged in a holding element. The holding element includes a receiving chamber, with the sample supply channel leading into the receiving chamber. Internally of receiving chamber, a distributing element is arranged. The passage openings for passage of the sample are formed by an inner side of the receiving chamber and by an outer side of the distributing element; preferably, for this purpose, the distributing element has recesses on the outer side. The sample distribution device is arranged in a device for liquid chromatography, wherein the sample will flow radially through the chromatography resin.05-03-2012

Ales Poruba, Prague 6 CZ

Patent application numberDescriptionPublished
20120031482PHOTOVOLTAIC CELL AND METHODS FOR PRODUCING A PHOTOVOLTAIC CELL - A photovoltaic device is provided that includes a substrate, a first transparent conductive layer positioned on the substrate, a plurality of transparent conductive rods positioned on the first transparent conductive layer and having a growth direction, the growth direction extending in a direction away from the substrate, a photovoltaically active layer covering the plurality of transparent conductive rods rods and a conductive layer positioned on the photovoltaically active layer.02-09-2012

Ales Strancar, Ajdovscina SI

Patent application numberDescriptionPublished
20100158944Method for influenza virus protection - A process for the purification of influenza virus or derivative thereof comprising the steps of: 06-24-2010

Ales Stuchlik, Celakovice CZ

Patent application numberDescriptionPublished
20120071453STEROIDE ANIONIC COMPOUNDS, METHOD OF THEIR PRODUCTION, USAGE AND PHARMACEUTICAL PREPARATION INVOLVING THEM - A compound with general formula I03-22-2012

Ales Svigelj, Lavrica SI

Patent application numberDescriptionPublished
20110317570Iterative Localization Techniques - The present invention refers to iterative localization techniques with wireless communication systems for rural environment with limited number of base stations in the range of the mobile station and urban environment with multipath propagation channel and several base stations in the range of mobile station.12-29-2011

Ales Vrána, Opava CZ

Patent application numberDescriptionPublished
20110097398REDUCTION OF CROSS-LINKING GELATIN IN GELATIN CAPSULES - The invention relates to compositions and methods for reducing cross-linking in the gelatin shell of gelatin capsules by incorporation of free amino acid into the capsule shell and by inclusion of an ester of carboxylic acid either into the capsule filling, and/or into the capsule shell and/or into the lubrication agent, or in combinations thereof. Described are soft gelatin capsules characterized by improved stability as compared with gelatin capsules that do not contain amino acid in the shell and carboxylic acid ester in the filling, shell or in the lubrication agent, or in combinations thereof.04-28-2011

Ales Vrána, Opava CZ

Patent application numberDescriptionPublished
20100008983Rasagiline soft gelatin capsules - Disclosed are formulations which are designed to release rasagiline mesylate while maintaining specific pharmacokinetic properties.01-14-2010
20110020438Crystallization Inhibitor and Its Use in Gelatin Capsules - The present invention describes soft gelatin capsules that encapsulate a water-insoluble active ingredient and an excipient composed of a crystallization inhibitor that stabilizes the water-insoluble inhibitor. The crystallization inhibitor being at least one mononacylglycerol compound whose acyl group is a fatty acid residue of 6-18 carbon atoms. The capsule contents are more resistant to turbidity, forming a coarse emulsion, and crystallization of the active ingredient compared with compositions absent the crystallization inhibitor.01-27-2011
20110097398REDUCTION OF CROSS-LINKING GELATIN IN GELATIN CAPSULES - The invention relates to compositions and methods for reducing cross-linking in the gelatin shell of gelatin capsules by incorporation of free amino acid into the capsule shell and by inclusion of an ester of carboxylic acid either into the capsule filling, and/or into the capsule shell and/or into the lubrication agent, or in combinations thereof. Described are soft gelatin capsules characterized by improved stability as compared with gelatin capsules that do not contain amino acid in the shell and carboxylic acid ester in the filling, shell or in the lubrication agent, or in combinations thereof.04-28-2011

Patent applications by Ales Vrána, Opava CZ

Ales Vyroubal, Postrelmov CZ

Patent application numberDescriptionPublished
20120075775Solid Electrolytic Capacitor with Improved Anode Termination - A capacitor containing a solid electrolytic capacitor element that includes an anode, dielectric, and solid electrolyte is provided. An anode lead extends from the anode and is electrically connected to an anode termination. The anode termination contains an upstanding portion that is bent or folded about an axis so that it possesses two or more sections. A slot (e.g., U-shaped) extends through the sections of the upstanding portion for receiving an anode lead. The resulting “folded” configuration of the anode termination increases the total thickness of the upstanding portion and its associated slot, which thereby enhances the degree of mechanical support and stability that the termination provides to the anode lead. This is particularly beneficial for thicker anode leads, such as those having a height and/or width of about 100 micrometers or more, in some embodiments about 200 micrometers or more, and in some embodiments, from about 250 to about 1000 micrometers.03-29-2012

Ales Vyroubal, Bludov Postrelmov CZ

Patent application numberDescriptionPublished
20100072179Laser Welding of Electrolytic Capacitors - A technique for laser welding an anode lead to an anode termination of an electrolytic capacitor is provided. The technique involves directing a laser beam through one or more refraction elements before it contacts the lead and anode termination. By selectively controlling the index of refraction and thickness of the refraction element, the angle at which the refraction element is positioned relative to the laser beam, etc., the laser beam may be directed to a precise weld location without substantially contacting and damaging other parts of the capacitor.03-25-2010