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Aldis
Aldis Darzins, Verona, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20080274488 | Covalent tethering of functional groups to proteins and substrates therefor - A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate and has at least two amino acid substitutions relative to the wild-type hydrolase. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein. | 11-06-2008 |
| 20090098627 | Method of immobilizing a protein or molecule via a mutant dehalogenase that is bound to an immobilized dehalogenase substrate and linked directly or indirectly to the protein or molecule - A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate and has at least two amino acid substitutions relative to the wild-type hydrolase. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein. | 04-16-2009 |
Aldis Darzins, Highlands Ranch, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20110124046 | Extracellular Secretion of Recombinant Proteins - Nucleic acids encoding secretion signals, expression vectors containing the nucleic acids, and host cells containing the expression vectors are disclosed. Also disclosed are polypeptides that contain the secretion signals and methods of producing polypeptides, including methods of directing the extracellular secretion of the polypeptides. Exemplary embodiments include cellulase proteins fused to secretion signals, methods to produce and isolate these polypeptides, and methods to degrade lignocelluiosic biomass. | 05-26-2011 |
Aldis Rauda, West Hollywood, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080300623 | MULTI-USE TWEEZER - The present disclosure is generally directed to a multi-tool with more than one tweezer tip. In an example embodiment the multi-tool includes two plates and an interposed spring component. The plates have a plurality of tweezer tip pairs and the spring component permits pivoting articulation of the plates in order to apply pinching forces by the different tweezer tip pairs upon an area of interest. | 12-04-2008 |
| 20090145451 | FINGER CLEANING MULTI-TOOL - The present disclosure is generally directed to a tool with multiple functions for use in cleaning fingers and fingernails. | 06-11-2009 |
| 20090165303 | DUAL-ACTION HAIR TRIMMER - An electric hair-trimming device includes a body having two opposite ends, two trimming heads mounted to the two opposite ends of the body, and two endcaps that detachably couple to the two opposite ends of the body to cover the two trimming heads. The endcaps each have a generally flat end surface such that the device can be stood upright on either of the endcaps. In an example embodiment, the trimming heads are provided by a nose-hair trimmer and a detail trimmer. And in another example embodiment, the nose-hair trimmer includes a high surface-porosity foil shroud. | 07-02-2009 |