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Albone

David Albone, Cambridgeshire GB

Patent application numberDescriptionPublished
20100292944CONDUCTIVITY SENSOR - A conductivity sensor is described in which electrodes are held in a desired position within a housing of the sensor by a number of slots accurately positioned within the housing. In one embodiment the slots are integrally formed within the housing. Once the electrodes have been inserted into the slots a thermoset resin is poured into the housing and cured. A through bore is then drilled through the housing, the electrodes and the cured resin to form a flow conduit through the sensor. A dual frequency excitation technique is also described that allows a measurement tote obtained of a polarisation resistance of the electrodes. In one embodiment this measurement is stored and used to correct subsequent conductivity measurements.11-18-2010

Earl F. Albone, Plymouth Meeting, PA US

Earl F. Albone, Blue Bell, PA US

Patent application numberDescriptionPublished
20110158904ANTIBODIES THAT BIND CELL-ASSOCIATED CA 125/O772P AND METHODS OF USE THEREOF - The present invention provides antibodies, and antigen-binding fragments of antibodies, fusion polypeptides and analogs that preferentially bind cell-associated CA 125/O772P polypeptides relative to shed CA 125/O772P polypeptides. The present invention further provides methods of preventing, managing, treating or ameliorating one or more symptoms associated with a CA 125/O772P-related disorder. In particular, the present invention provides methods of preventing, managing, treating, or ameliorating one or more symptoms associated with a cell proliferative disorder, such as cancer, e.g., ovarian cancer. The present invention still further provides methods for diagnosing a CA 125/O772P-related disorder or predisposition to developing such a disorder, as well as methods for identifying antibodies, and antigen-binding fragments of antibodies, that preferentially bind cell-associated CA 125/O772P polypeptides relative to shed CA 125/O772P polypeptides.06-30-2011