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Albelda
Carlos Artiles Albelda, Madrid ES
| Patent application number | Description | Published |
|---|---|---|
| 20090112502 | Methods and systems for assisting in the design of mobile surfaces of objects - A computer-aided method suitable for calculating the position of a mobile surface of an object such an aircraft that moves through a fluid medium, which is affected by at least an upstream or downstream object component, for achieving a predetermined value Vo of a predetermined object performance target, comprising the following steps: preparing a computer-implemented CFD model of said object having said mobile surface in a first position; solving said CFD model and obtaining the value Vi of said object performance target; if the difference between Vi and Vo is greater than a predetermined value, modifying the CFD model changing the position of the mobile surface in the CFD model and iterating the solving step. The invention also refers to a system for carrying out said method. | 04-30-2009 |
Steven Albelda, Philadelphia, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110195053 | Treatment of Non-Neuronal Cancer using HSV-1 Variants - A mutant herpes simplex virus which has been modified in the γ34.5 gene such that the gene is non-functional is used to treat a non-neuronal cancer such as a mesothelioma, ovarian carcinoma, bladder cancer or melanoma. Typically, the mutant herpes simplex virus has been modified within the BamHI restriction fragment of the long terminal repeat of the viral genome. | 08-11-2011 |
Steven M. Albelda, Bala Cynwyd, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100255486 | METHOD FOR DIAGNOSING LUNG CANCERS USING GENE EXPRESSION PROFILES IN PERIPHERAL BLOOD MONONUCLEAR CELLS - Methods and compositions are provided for diagnosing lung cancer in a mammalian subject by use of three or more selected genes, e.g., a gene expression profile, from the peripheral blood mononuclear cells (PBMC) of the subject which is characteristic of disease, a stage of the disease, or enables prognosis of recurrence of disease. The gene expression profile includes three or more genes of Table I, Table II, Table III, Table IV, Table V, Table VI or Table VII herein. Detection of changes in expression in the selected genes forming the gene expression profile from that of a reference gene expression profile are correlated with non-small cell lung cancer (NSCLC). One composition for use in such diagnosis includes three or more PCR primer-probe sets, wherein each primer-probe set amplifies a different polynucleotide sequence from the gene expression profile. Another composition for similar use contains a plurality of polynucleotides immobilized on a substrate, which probes hybridize to three or more gene expression products from genes in the gene expression profile. Still another composition involves detection of the protein expression products of genes from the gene expression profile. | 10-07-2010 |
Steven M. Albelda, Philadelphia, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110262466 | COMPOSITIONS CONTAINING THROMBOMODULIN DOMAINS AND USES THEREOF - Compositions are provided comprising a thrombomodulin domain linked to a targeting moiety that binds to a determinant on the surface of a target endothelial cell or red blood cell, wherein the thrombomodulin domain may be the extracellular domain, the N-terminal lectin-like domain, or an epidermal growth factor (EGF)-like domain. The targeting moiety may be a single chain antigen-binding domain (scFv), and the targeting moiety and thrombomodulin domain of the composition may be linked as a continuous polypeptide chain. Methods of delivery and use of a composition described herein are provided, as well as methods of treating or preventing thrombosis, inflammation, tissue ischemia, sepsis, acute lung injury (ALI), acute myocardial infarction (AMI), ischemic stroke, cerebrovascular disease, pulmonary embolism, or ischemic peripheral vascular disease is provided. | 10-27-2011 |
Virginie Albelda, Paris FR
| Patent application number | Description | Published |
|---|---|---|
| 20100001091 | Piezoelectric atomizer comprising a fragrancing liquid composition; fragrancing method - The invention relates to a cosmetic assembly comprising: | 01-07-2010 |