| Patent application number | Description | Published |
|---|
| 20080255064 | Methods for modulating cholecystokinin expression - The invention provides a method for upregulating cholecystokinin (CCK) expression in mammalian pancreatic islets by administrating a CCK upregulating agent. The increased CCK expression activates islet cell proliferation triggering an increase in pancreatic β-cell mass and plasma insulin levels. Accordingly, methods to produce a replenishable supply of islet cells and to ameliorate the symptoms associated with diabetes are also disclosed. | 10-16-2008 |
| 20090221677 | Methods for Reducing Body Fat and Increasing Lean Body Mass by Reducing Stearoyl-COA Desaturase 1 Activity - It is disclosed here that inhibiting the activity of the enzyme stearoyl-CoA desaturase (SCD1) in an animal causes the animal to have less body fat and greater lean body mass. The lower of SCD1 activity level can be accomplished by inhibiting activity of the enzyme or lowering levels of active enzyme in the subject. | 09-03-2009 |
| 20110060014 | Methods and compositions using stearoyl-CoA desaturase to identify triglyceride reducing therapeutic agents - The use of screening assays based on the role of human stearoyl-CoA desaturase-1 (“hSCD1”) in human diseases, disorders or conditions relating to serum levels of triglyceride, VLDL, HDL, LDL, total cholesterol, or production of secretions from mucous membranes, monounsaturated fatty acids, wax esters, and the like, is disclosed. Also disclosed are conventions useful in the prevention and/or treatment of such diseases. | 03-10-2011 |
| 20110071222 | POTENTIATORS OF INSULIN SECRETION - The present invention relates to a recognition that an analog of αKG can increase glucose-induced insulin secretion in vitro and in vivo in animals, particularly in mammals, and more particularly in humans and in rodents. By employing the methods of the invention, insulin secretion can be increased. | 03-24-2011 |
| 20110287084 | METHOD FOR REDUCING BODY FAT AND INCREASING LEAN BODY MASS BY REDUCING STEAROYL-COA DESATURASE 1 ACTIVITY - It is disclosed here that inhibiting the activity of the enzyme stearoyl-CoA desaturase (SCD1) in an animal causes the animal to have less body fat and greater lean body mass. The lower of SCD1 activity level can be accomplished by inhibiting activity of the enzyme or lowering levels of active enzyme in the subject. | 11-24-2011 |
| Patent application number | Description | Published |
|---|
| 20090063799 | Memory Protection For Embedded Controllers - System and method for protecting data in a system including a main processor, an embedded controller, and a memory. In response to a power-on-reset (POR), access to the memory is enabled, e.g., access by the embedded controller. First data is read from the memory (e.g., by the embedded controller) in response to the enabling, where the first data are usable to perform security operations for the system prior to boot-up of the main processor. The first data are used, e.g., by the embedded controller, to perform one or more security operations for the system, then access to the memory, e.g., by the embedded controller, is disabled, where after the disabling the memory is not accessible, e.g., until the next POR initiates enablement. | 03-05-2009 |
| 20090063865 | Configurable Signature for Authenticating Data or Program Code - System and method for authenticating data or program code via a configurable signature. Configuration information is retrieved from a protected first memory, e.g., an on-chip register, where the configuration information specifies a plurality of non-contiguous memory locations that store the signature, e.g., in an on-chip memory trailer. The signature is retrieved from the plurality of non-contiguous memory locations based on the configuration information, where the signature is useable to verify security for a system. The signature corresponds to specified data and/or program code stored in a second memory, e.g., in off-chip ROM. The specified data and/or program code may be copied from the second memory to a third memory, and a signature for the specified data and/or program code calculated based on the configuration information. The calculated signature may be compared with the retrieved signature to verify the specified data and/or program code. | 03-05-2009 |
| 20090113114 | Implementation of One Time Programmable Memory with Embedded Flash Memory in a System-on-Chip - System and method for implementing one time programmable (OTP) memory using embedded flash memory. A system-on-chip (SoC) includes a cleared flash memory array that includes an OTP block, including an OTP write inhibit field that is initially deasserted, a flash memory controller, and a controller. Data are written to the OTP block, including setting the OTP write inhibit field to signify prohibition of subsequent writes to the OTP block. The SoC is power cycled, and, in response, at least a portion of the OTP block is latched in a volatile memory, including asserting an OTP write inhibit bit based on the OTP write inhibit field, after which the OTP block is not writeable. In response to each subsequent power cycling, the controller is held in reset, the latching is performed, the controller is released from reset, and the flash array, now write protected, is configured to be controlled by the controller. | 04-30-2009 |
| 20090327678 | Enhancing Security of a System Via Access by an Embedded Controller to A Secure Storage Device - System and method for performing pre-boot security verification in a system that includes a host processor and memory, an embedded microcontroller with an auxiliary memory, e.g., an on-chip ROM, or memory controlled to prohibit user-tampering with the contents of the memory, and one or more pre-boot security components coupled to the embedded microcontroller. Upon power-up, but before host processor boot-up, the embedded microcontroller accesses the auxiliary memory and executes the program instructions to verify system security using the one or more pre-boot security components. The one or more pre-boot security components includes at least one identity verification component, e.g., a smart card, or a biometric sensor, e.g., a fingerprint sensor, a retinal scanner, and/or a voiceprint sensor, etc., and/or at least one system verification component, e.g., TPM, to query the system for system state information, and verify that the system has not been compromised. | 12-31-2009 |
| 20100036979 | External Direct Memory Access of Embedded Controller Memory - An embedded controller capable of providing direct memory access (DMA) to memory for a host. The controller may include a processor, a memory medium, and an interface coupled to the memory medium. The interface may be configured to couple to a host and receive a DMA request. The DMA request may include a request to read data from a memory location in the memory medium or a request to write data to a memory location in the memory medium. The DMA request may include a relative memory address. The interface may be configured to translate the relative memory address into a first address of the memory medium. Accordingly, the interface may perform operations according to the DMA request using the first address of the memory medium. The processor may be configured to operate according to data stored in the memory medium. | 02-11-2010 |
| 20100217957 | Structured Virtual Registers for Embedded Controller Devices - Techniques for using structured virtual registers in embedded systems are described. A virtual register structure definition provides a map of virtual registers within an embedded controller. The virtual registers are externally accessible and correspond to memory locations within the embedded controller. In various embodiments, an embedded controller and/or an external entity may store data in or read data from the virtual registers using the virtual register structure definition. The problems of manual tracking of virtual register addresses and manual transcription of virtual register addresses to program code are ameliorated. When the virtual register map changes, logical references in program code to particular virtual registers need not necessarily be changed. | 08-26-2010 |
| Patent application number | Description | Published |
|---|
| 20090313909 | Low density semi-rigid flame resistant foams - The present invention provides a low density, semi-rigid polyurethane foam made from the reaction product, at an isocyanate index of from about 100 to about 150, of at least one polyisocyanate and an isocyanate-reactive blend containing from about 15 wt. % to about 55 wt. %, based on the weight of the resin, of a difunctional or greater functionality polyether polyol, from about 3 wt. % to about 19 wt. %, based on the weight of the resin, of at least one polyether tetrol, and from about 7 wt. % to about 39 wt. %, based on the weight of the resin, of at least one non-halogenated polyester polyol in the presence of from about 5 wt. % to about 30 wt. %, based on the weight of the resin, of at least one non-hydroxy functional flame retardant and from about 1 wt. % to about 20 wt. %, based on the weight of the resin, of at least one cross linking agent, and optionally in the presence of one or more of catalysts, surfactants, chain extenders and blowing agents, wherein the semi-rigid polyurethane foam having a density of from about 2 to about 25 pcf meets at least a V-1 class rating in accordance with UL 94 V flammability testing. The low density, semi-rigid polyurethane foams of the present invention may find use in producing lightweight, rapidly erected barriers for protection of people such as soldiers, police officers and fire fighters from pursuit by adversaries. Barriers made with the inventive foam may also be used to limit access to already secured areas. | 12-24-2009 |
| 20100260941 | REINFORCED UV-A CURABLE COMPOSITE COMPOSITIONS AND METHODS - The present disclosure is directed to a process for forming a reinforced ultraviolet (UV) radiation-curable composite. The composite may be formed by applying reinforcing layers and resin layers to a substrate. The resin composition may include an aliphatic urethane acrylate oligomer, a polyfunctional acrylate monomer, and a photoinitiator. The composite formed on the substrate may be exposed to UV radiation to cure the composite on the substrate. The composite may be characterized in that it is cured within 10 minutes of exposure to UV radiation and does not exhibit oxygen inhibition effects, such as, for example, surface tack. The reinforced UV-curable composite may find utility, for example, as a rapid field repair patch in aerospace applications, among others. | 10-14-2010 |
| Patent application number | Description | Published |
|---|
| 20090297359 | High Modulus Metallic Component For High Vibratory Operation - A high modulus component, such as an aircraft engine turbine blade, is formed from a base metal that has a high modulus crystallographic orientation that is aligned with the primary, i.e. radial, direction of the turbine blade. The base metal is Ni, Fe, Ti, Co, Al, Nb, or Mo based alloy. Alignment of a high modulus direction of the base metal with the primary direction provides enhanced high cycle fatigue life. | 12-03-2009 |
| 20100000698 | CASTING SYSTEM FOR INVESTMENT CASTING PROCESS - A casting system includes a core and a shell positioned relative to the core. A barrier coating is applied on at least one of the core and the shell. | 01-07-2010 |
| 20100086411 | MODERATE DENSITY, LOW DENSITY, AND EXTREMELY LOW DENSITY SINGLE CRYSTAL ALLOYS FOR HIGH AN2 APPLICATIONS - A single crystal alloy for high AN | 04-08-2010 |
| 20100135846 | LOWER COST HIGH STRENGTH SINGLE CRYSTAL SUPERALLOYS WITH REDUCED RE AND RU CONTENT - A first embodiment of a nickel based alloy consists essentially of from 3.0 to 5.2 wt % chromium, from 1.5 to 3.0 wt % molybdenum, from 6.0 to 12.5 wt % tungsten, from 5.0 to 11 wt % tantalum, from 5.5 to 6.5 wt % aluminum, from 11 to 14 wt % cobalt, from 0.001 to 1.75 wt % rhenium, from 0.2 to 0.6 wt % hafnium, up to 0.05 wt % yttrium, up to 3.0 wt % ruthenium, and the balance nickel. Another embodiment of a nickel based alloy consists essentially of from 1.0 to 3.0 wt % chromium, up to 2.5 wt % molybdenum, from 11 to 16 wt % tungsten, from 4.0 to 8.0 tantalum, from 5.7 to 6.5 wt % aluminum, from 11 to 15 wt % cobalt, from 2.0 to 4.0 wt % rhenium, from 0.2 to 0.6 wt % hafnium, up to 0.05 wt % yttrium, up to 3.0 wt % ruthenium, and the balance nickel. | 06-03-2010 |
| 20100260613 | Process for preventing the formation of secondary reaction zone in susceptible articles, and articles manufactured using same - A process for reducing secondary reaction zone formation articles includes the steps of non-selective removing an external surface of an as-cast article free of coating to form an as-cast article having a surface substantially free of residual surface stress; and applying a coating material upon the surface substantially free of residual surface stress to form a coated as-cast article having a coating layer disposed upon the surface substantially free of residual surface stress. | 10-14-2010 |
| 20110143164 | LOW SULFUR NICKEL BASE SUBSTRATE ALLOY AND OVERLAY COATING SYSTEM - A coated article having an improved coating oxidation life includes a superalloy substrate material having a composition which includes sulfur, herein the sulfur is present in an amount less than 1 ppm; and an overlay coating formed over a surface of the substrate material. | 06-16-2011 |
| 20110256421 | METALLIC COATING FOR SINGLE CRYSTAL ALLOYS - A metallic coating for use in a high temperature application is created from a nickel base alloy containing from 5.0 to 10.5 wt % aluminum, from 4.0 to 15 wt % chromium, from 2.0 to 8.0 wt % tungsten, from 3.0 to 10 wt % tantalum, and the balance nickel. The metallic coating has particular utility in protecting single crystal superalloys used in high temperature applications such as turbine engine components. | 10-20-2011 |
| Patent application number | Description | Published |
|---|
| 20110143596 | SMART CARD CONNECTOR - A smart card connector may include a connector housing connected to a cover. The connector housing and the cover may define a channel for receiving the smart card. The connector may receive the smart card in an insertion direction. When the smart card is inserted into the smart card connector, contacts secured within the connector housing may establish an electrically conductive connection with contact pads on the surface of the smart card. The connector housing may be narrower than the cover in a second direction that is perpendicular to the first direction. The connector housing may define a first centerline that extends along the insertion direction, and the cover may define a second centerline that extends along the insertion direction. The first centerline may be offset from the second centerline. | 06-16-2011 |
| 20110159473 | ARRAY OF ELECTRICAL CONNECTORS HAVING OFFSET ELECTRICAL CONNECTORS - An array of electrical connectors is provided having a first plurality of electrical connectors configured to be mounted on a substrate, and a second plurality of electrical connectors configured to be mounted on the substrate at a location adjacent the first plurality of electrical connectors, such that the first plurality of electrical connectors is offset with respect to the second plurality of electrical connectors along an insertion direction. | 06-30-2011 |
| 20110159710 | ARRAY OF ELECTRICAL CONNECTORS HAVING OFFSET ELECTRICAL CONNECTORS - An array of electrical connectors is provided having a first plurality of electrical connectors configured to be mounted on a substrate, and a second plurality of electrical connectors configured to be mounted on the substrate at a location adjacent the first plurality of electrical connectors, such that the first plurality of electrical connectors is offset with respect to the second plurality of electrical connectors along an insertion direction. | 06-30-2011 |
| 20120030146 | Backplane Connector With Reduced Circuit Board Overhang - A right-angle electrical connector is configured to be mounted onto an upper mounting surface of a substrate that defines a bottom surface opposed from the upper mounting surface so as to define a thickness. The connector includes a connector housing and a plurality of electrical contacts retained by the connector housing. The connector housing overhangs an edge of the substrate and extends down with respect to the upper surface to a depth from the upper mounting surface that is less than the thickness of the substrate. | 02-02-2012 |
| Patent application number | Description | Published |
|---|
| 20090054907 | FLEXIBLE TUBE FOR CARTRIDGE FILTER - Embolic protection filtering devices and methods of making and using the same. The present invention may include an embolic protection filtering device including a filter cartridge that is slidable over medical devices, for example, guidewires. The filter cartridge may have a filter coupled thereto and may have desirable flexibility and trackability characteristics. | 02-26-2009 |
| 20090082722 | REMOTE NAVIGATION ADVANCER DEVICES AND METHODS OF USE - Various systems for advancing medical devices within a subject's body are provided that configured to engage the outer surface of the medical device at a number of points about the circumference of the medical device, to thereby grip the medical device for enabling advancement of the device. The advancing systems include engaging portions configured to engage the outer surface of a medical device at a number of points about the circumference of the medical device. The engaging portions preferably engage opposing sides of the medical device's outer surface over a predetermined longitudinal length, to clamp against a longitudinal portion of the medical device that provides improved surface contact with the medical device over conventional roller guides. Various methods for performing medical procedures utilizing various medical devices and advancer systems are also provided. | 03-26-2009 |
| 20100300956 | FLEXIBLE TUBE FOR CARTRIDGE FILTER - Embolic protection filtering devices and methods of making and using the same. The present invention may include an embolic protection filtering device including a filter cartridge that is slidable over medical devices, for example, guidewires. The filter cartridge may have a filter coupled thereto and may have desirable flexibility and trackability characteristics. | 12-02-2010 |
| 20110046618 | METHODS AND SYSTEMS FOR TREATING OCCLUDED BLOOD VESSELS AND OTHER BODY CANNULA - A method of treating an occluded blood vessel includes sensing the impedance at a plurality of locations around the circumference of the blood vessel at least two different frequencies to identify vascular occlusive material, and distinguish vascular occlusive material from the vessel wall. | 02-24-2011 |
| 20110152712 | Impedance Measurement Tissue Identification in Blood Vessels - A system for radio frequency (RF) wire guidance during RF occlusion canalization including a RF wire configured to travel through a blood vessel, an impedance measure unit configured to measure an electrical impedance between the RF wire and a reference electrode, a RF power source, an activation controller configured to connect the RF power source to the RF wire when the impedance measure unit indicates that the RF wire is contacting an occlusion material, a RF wire steering system; and a controller configured to activate the steering system to maintain the RF wire within the occlusion material based on impedance measured by the impedance measure unit. | 06-23-2011 |
| Patent application number | Description | Published |
|---|
| 20080251707 | OPTICAL CHASSIS, CAMERA HAVING AN OPTICAL CHASSIS, AND ASSOCIATED METHODS - A camera including a mount substrate, a detector on a first surface of the mount substrate, a spacer on the mount substrate, the spacer including a hole exposing the detector, a cover on the spacer, the cover covering the hole, the mount substrate, the spacer and the cover together sealing the detector, the cover having a planar surface facing the detector, and an external electrical interconnection for the detector provided outside the sealing, the external electrical interconnection being on a first surface and a second surface, different from the first surface, of the mount substrate, the external electrical interconnection adapted to connect the detector to an electrical contact pad. | 10-16-2008 |
| 20090073451 | Spectrally diverse, spatially sensitive apparatus and associated methods - A spectrometer for use with a desired wavelength range includes an array of filters. Each filter outputs at least two non-contiguous wavelength peaks within the desired wavelength range. The array of filters is spectrally diverse over the desired wavelength range, and each filter in the array of filters outputs a spectrum of a first resolution. An array of detectors has a detector for receiving an output of a corresponding filter. A processor receives signals from each detector, and outputs a reconstructed spectrum having a second resolution, the second resolution being higher than any of the first resolution of each filter. Filters and detectors may be arranged into a plurality of imaging units, each imaging unit including first and second filters and first and second photosensing regions. A processor receives signals from each imaging unit, and generates a reconstructed spatial image comprised of discrete spatial units corresponding to each imaging unit. | 03-19-2009 |
| 20090296228 | Integrated micro-optical systems - An integrated micro-optical system includes at least two wafers with at least two optical elements provided on respective surfaces of the at least two wafers, at least one of the two optical elements being a spherical lens. The resulting optical system presents a high numerical aperture. One of the optical elements may be a refractive element formed in a material having a high index of refraction. | 12-03-2009 |
| 20100272393 | Wafer based optical chassis and associated methods - An optical chassis includes a mount substrate an optoelectronic device on the mount substrate, a spacer substrate, and a sealer substrate. The mount substrate, the spacer substrate and the sealer substrate are vertically stacked and hermetically sealing the optoelectronic device. An external electrical contact for the optoelectronic device is provided outside the sealing. At least part of the optical chassis may be made on a wafer level. A passive optical element may be provided on the sealer substrate or on another substrate stacked and secured thereto. | 10-28-2010 |
| 20110068258 | NONROTATIONALLY SYMMETRIC LENS, IMAGING SYSTEM INCLUDING THE SAME, AND ASSOCIATED METHODS - A singlet lens with opposing first and second surfaces has at least one surface being nonrotationally symmetric, the singlet lens substantially maintaining a ratio of magnification along orthogonal axes. The nonrotationally symmetric surface may be used in an imaging system, which may be used in a mobile handset. | 03-24-2011 |
| 20110170188 | MONOLITHIC POLARIZING DIFFRACTIVE STRUCTURES AND ASSOCIATED METHODS - A monolithic polarizing diffractive structure includes a system having at least two parallel continuous planar surfaces, a diffractive pattern on one of the at least two parallel continuous surfaces, the diffractive pattern including at least two diffractive elements integral with the one of the at least two continuous surfaces, the at least two diffractive elements defining a monolithic diffractive pattern, and a polarizing pattern on one of the at least two parallel continuous surfaces. The polarizing pattern includes at least two polarizing elements, each polarizing element corresponding to a respective diffractive element, the at least two polarizing elements outputting polarizations rotated with respect to one another, the at least two polarizing elements defining a monolithic polarizing pattern. | 07-14-2011 |
| Patent application number | Description | Published |
|---|
| 20090108511 | Variable force spring - A variable force spring that includes an elongated, pre-stressed strip of retractable spring material that is formed into coils and having a variation in cross-sectional mass along the length. In one instance, the variation in cross-sectional mass along the length of the retractable spring is achieved by varying the width of the pre-stressed spring along its length. | 04-30-2009 |
| 20090112163 | Fluid delivery device with variable force spring - A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as antibiotics, blood clotting agents, analgesics, and like medicinal agents from collapsible containers at a uniform rate. The dispenser includes a novel stored energy source that is provided in the form of a compressible-expandable member that functions to continuously and uniformly expel fluid from the apparatus reservoir. The apparatus further includes a novel fluid flow control assembly that precisely controls the flow of the medicament solutions from the apparatus reservoir to the patient. | 04-30-2009 |
| 20100056998 | Two part fluid dispenser - A dispensing device for dispensing medicaments to a patient that is made up of first and second stand-alone, interconnectable assemblies. The first of these assemblies comprises a fluid reservoir assembly that houses a fluid reservoir defining component while the second assembly comprises a fluid delivery and control assembly that includes a novel flow control means that functions to control the flow of medicinal fluid from the fluid reservoir of the first assembly toward the patient via a plurality of fluid flow control passageways. Because the stand-alone fluid delivery and control assembly is initially totally separate from the fluid reservoir assembly of the apparatus, the fluid flow passageways of the fluid delivery and control assembly can be effectively sterilized using conventional gamma ray sterilization techniques without adversely affecting the medicament contained within the fluid reservoir of the apparatus. | 03-04-2010 |
| 20100222741 | Fluid delivery device with variable force spring - A compact fluid dispenser for use in controllably dispensing fluid medicaments such as antibiotics, blood clotting agents, analgesics, and like medicinal agents from collapsible containers at a uniform rate. The dispenser includes a novel stored energy source that is provided in the form of a compressible-expandable member that functions to continuously and uniformly expel fluid from the apparatus reservoir. The apparatus further includes a novel fluid flow control assembly that precisely controls the flow of the medicament solutions from the apparatus reservoir to the patient. | 09-02-2010 |
| 20100241074 | Fluid delivery device with variable force spring - A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as antibiotics, blood clotting agents, analgesics, and like medicinal agents from collapsible containers at a uniform rate. The dispenser includes a novel stored energy source that is provided in the form of a compressible-expandable member that functions to continuously and uniformly expel fluid from the apparatus reservoir. The apparatus further includes a novel fluid flow control assembly that precisely controls the flow of the medicament solutions from the apparatus reservoir to the patient. | 09-23-2010 |
| 20100312187 | Pain management dispenser - A dispensing device for dispensing pain management medicaments to a patient comprising first and second threadably interconnectable sub-assemblies. The first of these sub-assemblies houses a novel collapsible fluid reservoir defining component while the second comprises a fluid delivery and control assembly that includes a novel flow control means that functions to control the flow of medicinal fluid from the fluid reservoir of the collapsible reservoir defining component toward the patient via a plurality of fluid flow control passageways. | 12-09-2010 |
| 20110251556 | Fluid dispenser - A dispensing device for dispensing pain management medicaments to a patient comprises first and second threadably interconnectable sub-assemblies. The first of these sub-assemblies houses a fluid reservoir defining component while the second comprises a fluid delivery and control assembly that includes a novel flow control means that functions to control the flow of medicinal fluid from the fluid reservoir of the first sub-assembly toward the patient via strategically formed flow control passageways. | 10-13-2011 |
| 20110282300 | Apparatus for dispensing medicinal fluids and method of making same - A dispensing device and the method of making same for dispensing medicaments to a patient that includes a housing, a first assembly connected to the first end of the housing that includes a body portion, and a penetrating sub-assembly. The first assembly also includes a rate control chip of novel construction that is connected to the penetrating sub-assembly and functions to control the rate of flow of medicinal fluid to the patient. Disposed within the housing is a second assembly that includes a shuttle, a collapsible container carried by the shuttle and a plurality of variable force springs that function to thrust the collapsible container into penetrating engagement with the penetrating member of the penetrating assembly and then to collapse the collapsible container to deliver the medicinal fluid to the patient. Connected to the second end of the housing is a novel third assembly that includes an operating member that is threadably connected to the shuttle. The operating member functions to controllably move the shuttle forwardly of the housing. The apparatus also includes a novel locking mechanism that releasably locks the operating member against rotation relative to the shuttle. | 11-17-2011 |
