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Alam, US
Abu Alam, Lake Forest, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20090123527 | METHOD OF INDUCING TOPICAL ANESTHESIA AND TRANSDERMAL PATCH - Disclosed is a method of inducing topical anesthesia in a tissue or organ of an animal comprising providing an aqueous gel formulation comprising water, an anesthetic (e.g., lidocaine hydrochloride), a viscoelastic polymer, and a tonicity modifier, wherein the aqueous gel formulation is free of preservatives and phosphate buffer, is isotonic with physiological fluids, and is sterile and has low particulate count. Also disclosed are a transdermal patch comprising the aqueous gel formulation suitable for applying on the skin of a patient and a method of controlling pain therewith. | 05-14-2009 |
| 20120034307 | Aqueous gel formulation and method for inducing topical anesthesia - Disclosed is a stable aqueous gel formulation suitable for topical use comprising water, an anesthetic (e.g., lidocaine hydrochloride), a viscoelastic polymer, and a tonicity modifier, wherein the aqueous gel formulation is free of preservatives and phosphate buffer, is isotonic with physiological fluids, and is sterile and has low particulate count. Also disclosed is a method of inducing topical anesthesia on a tissue or organ, e.g., the eye, of an animal comprising providing a stable aqueous gel formulation comprising water, an anesthetic, a viscoelastic polymer, and a tonicity modifier, wherein the aqueous gel formulation is free of preservatives and phosphate buffer, is isotonic with physiological fluids, and is sterile, and topically administering an effective amount of the aqueous gel formulation to the tissue or organ of the animal. | 02-09-2012 |
Aftab Alam US
| Patent application number | Description | Published |
|---|---|---|
| 20120143510 | HIGH RESOLUTION ATTRIBUTES FOR SEISMIC DATA PROCESSING AND INTERPRETATION - A visualization method for the computation and display of seismic attributes from time-frequency spectral analysis enables high resolution investigation of 3D seismic data for the exploration of oil and gas. First, high frequency resolution time derivative or space derivative of the amplitude and phase spectra of time-windowed signals are computed. Second, the derivatives are transformed into seismic attributes that are suitable for seismic data processing or interpretation. Applications for the method are illustrated with graphical screen 3D volume displays of dip and azimuth, curvature and faults. Aside from providing high resolution these displays may improve the productivity of a seismic interpreter or data processor. | 06-07-2012 |
Aftab Alam, Sugar Land, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20090292475 | Time-Space Varying Spectra for Seismic Processing - A method and visualization apparatus for spectral analysis of time-and-space varying signals enables high resolution investigation of 3D seismic data for the exploration of oil and gas. The method extrapolates multi-resolution short windows into an average long window then computes its FFT. Extrapolation uses the continuity relationship between data inside and outside of short windows. Applications of the method are illustrated with graphical screen 3D volume displays of amplitude spectra, dip and azimuth, curvature and faults (figure below). Aside from high resolution these displays improve the productivity of a seismic interpreter. | 11-26-2009 |
Akm K. Alam, Erie, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20090006069 | REAL-TIME PERFORMANCE MODELING OF APPLICATION IN DISTRIBUTED ENVIRONMENT AND METHOD OF USE - A system and method of managing computing systems and, more particularly, to a system and method for modeling applications in a network. The method includes determining dependency of components in a shared distributed computing environment and measuring consumption of the dependent components. The method further includes building a model to compare component behavior with a current load of the dependent components to optimize component performance or to find a deviation and hence a “troubled spot”. The system includes a local agent configured to perform the method and to provide data to a centralized storage. | 01-01-2009 |
Akm Kamrul Alam, Erie, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20080319926 | METHOD FOR DYNAMIC USAGE BILLING - A computer-implemented method of calculating a bill for resource usage in an application hosting environment. Resource information is gathered on each computer system resource from a set of resources which are memory resources, SAN resources, CPU resources, hard disk resources, network resources, and middleware resources. A cost per unit of resource is determined for each resource. Usage information is gathered on all resources utilized by at least one computer application during a billing period. A usage sum is determined for each resource utilized which includes a sum of all resource units utilized for each resource. A total usage cost is determined for each resource utilized. The total usage cost is a product of the cost per unit and the usage sum. A dynamic usage bill is created based on a total charge which is a sum of the total usage costs for all resources utilized during the billing period. | 12-25-2008 |
Ashraf Alam, West Lafayette, IN US
| Patent application number | Description | Published |
|---|---|---|
| 20080280776 | Method and apparatus for detection of molecules using a sensor array - Apparatus and methods for detecting molecules in a fluidic environment are provided, including nanodevices and methods for fabricating, functionalizing, and operating such nanodevices. At least one of the methods includes selective heating of nanodevices in an array. | 11-13-2008 |
| 20120021918 | DNA Sequencing and Amplification Systems Using Nanoscale Field Effect Sensor Arrays - In one aspect, described herein are field effect chemical sensor devices useful for chemical and/or biochemical sensing. Also provided herein are methods for single molecule detection. In another aspect, described herein are methods useful for amplification of target molecules by PCR. | 01-26-2012 |
Daniel Alam, Shaker Heights, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20090042294 | Hydroxyphenyl cross-linked macromolecular network and applications thereof - A dihydroxyphenyl cross-linked macromolecular network is provided that is useful in artificial tissue and tissue engineering applications, particularly to provide a synthetic macromolecular network for a wide variety of tissue types. In particular, artificial or synthetic cartilage, vocal cord material, vitreous material, soft tissue material and mitral valve material are described. In an embodiment, the network is composed of tyramine-substituted and cross-linked hyaluronan molecules, wherein cross-linking is achieved via peroxidase-mediated dityramine-linkages that can be performed in vivo. The dityramine bonds provide a stable, coherent hyaluronan-based hydrogel with desired physical properties. | 02-12-2009 |
| 20090142309 | Hydroxyphenyl cross-linked macromolecular network and applications thereof - A dihydroxyphenyl cross-linked macromolecular network is provided that is useful in artificial tissue and tissue engineering applications, particularly to provide a synthetic macromolecular network for a wide variety of tissue types. In particular, artificial or synthetic cartilage, vocal cord material, vitreous material, soft tissue material and mitral valve material are described. In an embodiment, the network is composed of tyramine-substituted and cross-linked hyaluronan molecules, wherein cross-linking is achieved via peroxidase-mediated dityramine-linkages that can be performed in vivo. The dityramine bonds provide a stable, coherent hyaluronan-based hydrogel with desired physical properties. | 06-04-2009 |
| 20090143766 | Hydroxyphenyl cross-linked macromolecular network and applications thereof - A dihydroxyphenyl cross-linked macromolecular network is provided that is useful in artificial tissue and tissue engineering applications, particularly to provide a synthetic macromolecular network for a wide variety of tissue types. In particular, artificial or synthetic cartilage, vocal cord material, vitreous material, soft tissue material and mitral valve material are described. In an embodiment, the network is composed of tyramine-substituted and cross-linked hyaluronan molecules, wherein cross-linking is achieved via peroxidase-mediated dityramine-linkages that can be performed in vivo. The dityramine bonds provide a stable, coherent hyaluronan-based hydrogel with desired physical properties. | 06-04-2009 |
Hasan B. Alam, Natick, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100317047 | Biomarkers of Hemorrhagic Shock - Methods for the use of claudin-3 as a biomarker for diagnosis and prognosis, and for monitoring the efficacy of treatment, in hemorrhagic shock (HS). | 12-16-2010 |
John Alam, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090215856 | Methods for monitoring IL-18 - This invention relates to methods for monitoring IL-18. | 08-27-2009 |
John J. Alam, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100189688 | Dose forms comprising VX-950 and their dosage regimen - The present invention relates to antiviral therapies and compositions for treating or preventing Hepatitis C infections in patients and relates to other methods disclosed herein. The invention also relates to kits and pharmaceutical packs comprising compositions and dosage forms. The invention also relates to processes for preparing these compositions, dosages, kits, and packs. | 07-29-2010 |
| 20120039850 | HCV Combination Therapies Comprising Pegylated Interferon, Ribavirin and Telaprevir - The invention relates to combination therapies for the treatment of hepatitis C virus with telaprevir and pegylated interferon alfa-2a with or without ribavirin. The invention relates to the treatment of patients with bridging fibrosis infected with HCV using the combination therapy. | 02-16-2012 |
John Jahangir Alam, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120289511 | COMPOSITIONS AND METHODS FOR TREATING ALZHEIMER'S DISEASE - The present invention provides compositions for reducing amyloid plaque burden associated with Alzheimer's disease and methods of using the same. | 11-15-2012 |
Kamrul Alam, Longmont, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20090094592 | System and Method for Replacing an Application on a Server - A system and method for controlling access to first and second applications in a shared storage. A first server requests from a first local storage a copy of an application identified by a first hierarchical directory. The first server request is redirected from the first local storage to the first application in the shared storage. The first application in the shared storage has a second, extended hierarchical directory comprising the first hierarchical directory plus a lower level qualifier. Subsequently, a second server requests from a second local storage a copy of an application identified by the first hierarchical directory. The second server request is redirected from the second local storage to the second application in the shared storage. The second application in the shared storage has a third, extended hierarchical directory comprising the first hierarchical directory plus a lower level qualifier different than the lower level qualifier of the second, extended hierarchical directory. The second application can be a more recent version of the first application. Also, there can be a proxy server which routed the request for the application identified by the first hierarchical directory to the first server, and further comprising the step of reconfiguring the proxy server to route subsequent requests for the application identified by the first hierarchical directory to the second server instead of the first server. | 04-09-2009 |
Mahbubul Alam, Mckinney, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20100081432 | LOCALLY PROVIDING CORE-NETWORK SERVICES - The present disclosure includes a system and method for locally providing core-network services. In some implementations, a method includes receiving, from a first network device, a request for a service provided by a core network native to a second network device. The service is provided to the first network device independent of the core network. | 04-01-2010 |
Mansoor Alam, Rocky Hill, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090129735 | OPTICAL FIBER HAVING REDUCED DEFECT DENSITY - An optical fiber comprising a multimode glass core having a diameter of at least 250 microns and an index of refraction and a polymer cladding having a thickness and contactingly surrounding a glass portion of the fiber so as to define an interface between the glass portion and the polymer cladding. The polymer cladding can have a first index of refraction that is less than the index of refraction. The fiber can comprise a density of less than 0.25 non-conforming regions having a diameter of 25 microns or greater per millimeter of length along the fiber, where each of the non-conforming regions is a region visible to the human eye under an optical microscope and having at least a portion thereof within a selected distance of the interface. The selected distance can be less than or equal to the thickness of the polymer cladding. The optical microscope can have a total magnification of about 200. The polymer cladding can be applied to at least a part of the optical fiber in at least a class 1000 environment. Methods of using optical fibers, including receiving with an optical fiber optical energy from a source and guiding the optical energy with the optical fiber, wherein the optical energy comprises at least one of 1) pulses each comprising a peak power of at least 10 kW, 2) an average power of at least 50 Watts, or 3) an average power density of at least 2.9 kW/cm | 05-21-2009 |
Md Nazmul Alam, Columbia, SC US
| Patent application number | Description | Published |
|---|---|---|
| 20120133373 | Non-Intrusive Cable Fault Detection and Methods - In accordance with certain embodiments of the present disclosure, a cable fault detection device is described. The device includes a conformal monopole structure and a ground plane structure. The ground plane structure is configured to be generally parallel to the cable longitudinal axis. | 05-31-2012 |
M. Khairul Alam, Athens, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20120227588 | CARBON FIBER COMPOSITE DISCHARGE ELECTRODE - A discharge electrode using carbon fibers, nanofibers and/or nanotubes to generate the corona discharge. The invention contemplates carbon fiber electrodes with or without a polymer matrix to form a composite, and a supporting configuration in which the fibers are wrapped helically around a supporting rod that extends along the length of the electrode. Another supporting configuration includes the fibers stretched across the gas flow path. Yet another supporting configuration includes mounting the fibers along the length of the support rod substantially parallel to the rod. | 09-13-2012 |
Mohammad Alam, Mobile, AL US
| Patent application number | Description | Published |
|---|---|---|
| 20090103638 | Method and system for increasing transmission speed of wired or wireless signals while minimizing the bit error rate - A communication system is provided which offers increased transmission speed while maintaining a low bit error rate. At the transmitter, a digital input is entered and a microprocessor determines from a particular subset of pulse sequence codes a single sequence of pulse coefficients that corresponds to that particular digital input. The sequence of pulse coefficients are then multiplied by a pulse shape, modulate and transmitted. At the receiver, the modulated pulses are demodulated. The demodulated pulses are then, on a pulse by pulse basis, subtracted from each of the subset of pulse sequences with the absolute values of each pulse for each pulse sequence being summed. A comparator selects a sequence of pulse coefficients corresponding to the lowest summed value of a particular pulse sequence, which is then mapped to a digital signal which is the same digital signal as the digital input. | 04-23-2009 |
Mohammed S. Alam, Grayslake, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20090191833 | HIGH PERFORMANCE CMOS RADIO FREQUENCY RECEIVER - A high performance radio frequency receiver includes a low noise amplifier with large binary and stepped gain control range, controlled impedance, and enhanced blocker immunity, for amplifying and converting a radio frequency signal to a current; a pulse generator for generating in-phase and quadrature pulses; a crossover correction circuit and pulse shaper for controlling a crossover threshold of the pulses and interaction between in-phase and quadrature mixers; and a double balanced mixer for combining the RF signal with the pulses to generate an intermediate frequency or baseband zero intermediate frequency current-mode signal. The in-phase and quadrature pulses have a duty cycle of 20-35%. The intermediate frequency signal and second order harmonics may be filtered with a high frequency low pass filter and a current injected complex direct-coupled filter. Decreased die size, current drain, cost, and complexity, as well as improvements in gain, 1/f noise, noise figure, sensitivity, and linearity may result. | 07-30-2009 |
Mohammed Shah Alam, Chandler, AZ US
| Patent application number | Description | Published |
|---|---|---|
| 20110237211 | Reconfigurable Diversity Receiver - A method may include reconfigurably enabling one of a first downconverter and a second converter and disabling the other the second downconverter, wherein the first downconverter and the second downconverter are integral to a receiver unit of as wireless communications terminal. The method may also include frequency downconverting received wireless communication signals by the enabled downconverter. The method may also include processing the downconverted wireless communication signals by a primary path if the first downconverter is enabled, and processing the downconverted wireless communication signals by a diversity path if the second downconverter is enabled. | 09-29-2011 |
Mohsiul Alam, Chandler, AZ US
| Patent application number | Description | Published |
|---|---|---|
| 20080240632 | SUPPORT DAMPERS FOR BEARING ASSEMBLIES AND METHODS OF MANUFACTURE - A support damper is provided for a bearing assembly to improve the damping capabilities of an uncentered squeeze film damper and to provide a support structure stiffness to minimize rotor to structure unbalance response. In one embodiment, and by way of example only, the support damper includes an inner ring, an outer ring, and a U-shaped beams. The inner ring is configured to be disposed around the bearing assembly and to extend axially along a portion thereof. The outer ring is spaced apart from the inner ring and extends radially outwardly relative thereto. The U-shaped beams couples the inner ring to the outer ring. Methods of manufacturing the support damper are also provided. | 10-02-2008 |
| 20080267767 | SEALS, SEALED SYSTEMS, AND METHODS FOR SEALING A SHAFT - In one embodiment, and by way of example only, a seal is provided for sealing a hollow shaft, where the hollow shaft has an inner surface that may be uneven due to shot peening. The seal includes an axially extending ring section having a first end, a second end, an inner surface, and a disk section disposed substantially perpendicular to the ring section inner surface between the ring section first and second ends. The seal conforms to the shaft inner surface to stop oil leakage. | 10-30-2008 |
| 20090060717 | SYNCHRONOUS SIGNAL GENERATOR FOR TRIM BALANCING OF JET ENGINE - A synchronous signal generator is provided for use in conjunction with an aircraft engine having a spool and an engine output shaft driven by the spool. The synchronous signal generator includes a generator housing, a generator output member rotatably mounted in the generator housing, a once-per-revolution timing mark on the generator output member, and conversion gearing disposed within the housing and configured to couple the engine output shaft to the generator output member. The conversion gearing rotates the generator output member at substantially the same rotational frequency as the spool when the conversion gearing is coupled to the engine output shaft. | 03-05-2009 |
| 20090110543 | SEQUENTIAL STIFFNESS SUPPORT FOR BEARING ASSEMBLIES AND METHOD OF FABRICATION - A sequential stiffness support is provided for a bearing assembly to improve vibration characteristics of a gas turbine engine and to provide a variable structural stiffness to the support to minimize unbalance load transmissibility. In one embodiment, and by way of example only, the sequential stiffness support includes an inner ring, an outer ring, and means for coupling the inner ring and the outer ring. The sequential stiffness support is configured to provide a first stiffness support at a first engine speed and a second stiffness support at speeds greater than the first engine speed. Methods of manufacturing the sequential stiffness support are also provided. | 04-30-2009 |
| 20090110572 | ANISOTROPIC BEARING SUPPORTS FOR TURBOCHARGERS - An exemplary anisotropic member ( | 04-30-2009 |
| 20090269185 | DAMPING SYSTEMS FOR USE IN ENGINES - Damping systems and engines including the damping systems are provided. In one embodiment, and by way of example only, the damping system includes a rotor, a bearing assembly mounted to the rotor, a spring cage disposed around the bearing assembly, an axially-extending housing surrounding the spring cage, a first squeeze film damper formed between the bearing assembly and the spring cage, and a second squeeze film damper formed between the spring cage and the axially-extending housing. | 10-29-2009 |
| 20120121446 | ANISOTROPIC BEARING SUPPORTS FOR TURBOCHARGERS - An exemplary anisotropic member supports a semi-floating bearing in a bore and can reduce non-synchronous vibration of the bearing in the bore. An anisotropic member can include an annular body configured to receive a semi-floating bearing and to space the bearing a distance from a bore surface and can be configured to impart anisotropic stiffness and damping terms to the semi-floating bearing when positioned in the bore. Such a member is suitable for use in a rotating assembly for a turbocharger where the bearing may be a semi-floating bearing. Various exemplary members, bearings, housings, assemblies, etc., are disclosed. | 05-17-2012 |
Muhammad Alam, West Lafayette, IN US
| Patent application number | Description | Published |
|---|---|---|
| 20110147715 | Medium Scale Carbon Nanotube Thin Film Integrated Circuits on Flexible Plastic Substrates - The present invention provides device components geometries and fabrication strategies for enhancing the electronic performance of electronic devices based on thin films of randomly oriented or partially aligned semiconducting nanotubes. In certain aspects, devices and methods of the present invention incorporate a patterned layer of randomly oriented or partially aligned carbon nanotubes, such as one or more interconnected SWNT networks, providing a semiconductor channel exhibiting improved electronic properties relative to conventional nanotubes-based electronic systems. | 06-23-2011 |
Muhammad Ashraful Alam, West Lafayette, IN US
| Patent application number | Description | Published |
|---|---|---|
| 20120279846 | CAPACITIVE MICROELECTROMECHANICAL SWITCHES WITH DYNAMIC SOFT-LANDING - A microelectromechanical system (MEMS)-based electrical switch. The electrical switch includes a moveable electrode, a dielectric layer positioned adjacent the moveable electrode on a first side of the dielectric layer and spaced apart from the moveable electrode when the moveable electrode is in an inactivated position and in contact with the moveable electrode when the moveable electrode is in an activated position, and a substrate attached to the dielectric layer on a second side opposite to the first side, the moveable electrode is configured to brake prior to coming in contact with the dielectric layer when the moveable electrode is switched between the inactivated state and the activated state. | 11-08-2012 |
Munir Alam, Chaple Hill, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20080213296 | Immunogen - The present invention relates, in general, to an immunogen for inducing antibodies that neutralize a wide spectrum of HIV primary isolates. The invention also relates to a method of inducing anti-HIV antibodies using same. | 09-04-2008 |
Munir S. Alam, Durham, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20110159037 | METHODS OF TREATING AND PROTECTING AGAINST HUMAN IMMUNODEFICIENCY VIRUS - The present invention relates, in general, to human immunodeficiency virus (HIV), and, in particular, to a method of inducing neutralizing antibodies against HIV, to a method of inducing antibodies protective against HIV and to compounds and compositions suitable for use in such methods. | 06-30-2011 |
Murad Alam, Chicago, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20090104252 | WOUND DRESSING FOR IMPROVING SCARRING - An occlusive wound dressing for application to wound sites to accelerate the healing process and improve the appearance of the final mature scar including a silicone gel sheet and antimicrobial silver disposed in the silicone gel sheet where the silver may be present in the form of particles or wires and the particles or wires may be disposed in the silicone gel sheet in a grid pattern or as a lattice, and an adhesive may be present on at least one face of the silicone gel sheet. The adhesive may be present in the form of spaced lines with adhesive-free areas between the lines containing the antimicrobial silver. It is preferred that an antibruising agent is also included in the silicone gel. | 04-23-2009 |
| 20090104292 | TOPICAL ARNICA TREATMENT FOR REDUCING BRUISING - A method of preventing post-surgery, post-laser treatment or post-traumatic bruising of the skin comprising applying topically to the affected area of the skin a treatment comprising at least 15% by weight | 04-23-2009 |
Muzaffar Alam, Clifton, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20110071150 | INDOLE DERIVATIVES AS CRAC MODULATORS - Compounds of the formula I: | 03-24-2011 |
| 20120230951 | ANTIVIRAL COMPOUNDS - The present invention provides compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection. | 09-13-2012 |
Naveed Alam, Freehold, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100325293 | Graphical User Interface (GUI) for Administering a Voice Over Internet Protocol (VOIP) Network Implementing Media Aggregation - A graphical user interface (GUI) is disclosed that allows a user to identify routers, communities, residents and media aggregation managers existing on a network. The user may interactively select a path that includes two media aggregation managers and at least one router. The GUI predicts scheduled bandwidth utilization along the selected path for a variety of residents wishing to communicate across the path. The GUI may be utilized for initializing all media aggregation managers on the network along with provisioning each of the routers on the selected path. The GUI provisions all of the routers and initializes all of the media aggregation managers on the selected path simultaneously in order to accomplish the predicted schedule of usage provided by the GUI to the user and force all communication packets communicated between the residents to travel along the selected path. | 12-23-2010 |
| 20120224586 | GRAPHICAL USER INTERFACE (GUI) FOR ADMINISTERING A NETWORK IMPLEMENTING MEDIA AGGREGATION - A graphical user interface (GUI) is disclosed that allows a user to identify routers, communities, residents and media aggregation managers existing on a network. The user may interactively select a path that includes two media aggregation managers and at least one router. The GUI predicts scheduled bandwidth utilization along the selected path for a variety of residents wishing to communicate across the path. The GUI may be utilized for initializing all media aggregation managers on the network along with provisioning each of the routers on the selected path. The GUI provisions all of the routers and initializes all of the media aggregation managers on the selected path simultaneously in order to accomplish the predicted schedule of usage provided by the GUI to the user and force all communication packets communicated between the residents to travel along the selected path. | 09-06-2012 |
Rowshon Alam, Needham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100280098 | RECEPTOR TARGETED OLIGONUCLEOTIDES - Disclosed herein are oligonucleotide conjugates that include ligands that target cell receptors that mediate endocytosis. The ligands can include peptides and small molecules. The conjugates can include carrier macromolecules to which the ligands and oligonucleotides are attached, or conjugates where an oligonucleotide is attached to a ligand in the absence of a carrier macromolecule. The oligonucleotides can include therapeutic oligonucleotides, such as siRNA, antisense RNA and miRNA. The ligand can be an RGD peptide. Also disclosed herein are methods of delivering the conjugates to cells in subjects. | 11-04-2010 |
Samim Alam, Fargo, ND US
| Patent application number | Description | Published |
|---|---|---|
| 20120316309 | Polymers Derived From Plant Oil - Polymers and copolymers are formed from vinylether monomers having fatty acid ester pendent groups derived from plant oils, such as soybean oil. | 12-13-2012 |
Samina Alam, Hershey, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090117081 | PARVOVIRUS METHODS AND COMPOSITIONS FOR KILLING NEOPLASTIC CELLS - According to the invention, parvoviruses such as the adeno-associated virus Type 2 (AAV2) are found to be oncolytic, selectively mediating apoptosis in cancer cells and their precursers, while leaving healthy cells intact. The invention thus comprises a method of killing cancer and other neoplastic and preneoplastic cells by administration of AAV2 virus, viral particles, products or replication incompetent vectors derived there from to said cells, and pharmaceutical compositions comprising the same. | 05-07-2009 |
| 20120213736 | PARVOVIRUS METHODS AND COMPOSITIONS FOR KILLING NEOPLASTIC CELLS - According to the invention, parvoviruses such as the adeno-associated virus Type 2 (AAV2) are found to be oncolytic, selectively mediating apoptosis in cancer cells and their precursors, while leaving healthy cells intact. The invention also includes a method of killing cancer and other neoplastic and preneoplastic cells by administrating to said cells the AAV2 proteins Rep78 or Rep 68, expression constucts encoding the same, or pharmaceutical compositions comprising the same. | 08-23-2012 |
Shakh Alam, Chicago, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20120197729 | SHELF-BASED PROMOTION TARGETING - A system and method for implementing promotions in a retail environment is provided. Transceivers located at one or more locations within the retail environment are adapted for communication with personal mobile devices carried by shoppers. Promotions can be offered and accepted based on factors such as a shopper's location within a store, shopper identity, shopper purchase history, shopper promotion redemption history, date and time and other factors. Applicable promotions are then activated within the retailer point-of-sale system for application during checkout. | 08-02-2012 |
Sheikh Kaisar Alam, Somerset, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100076314 | SYSTEM AND METHOD FOR CREATING VIRTUAL FORCE FIELD - The present invention describes systems and methods for creating a virtual force field. A field source may be scanned over a region of interest on an object using a scanning technique such as vector scanning or raster scanning. The techniques disclosed herein describe applying the force field over volumetric (spatial) regions that can extend beyond the dimensions of the focal region of the force-field source (e.g., acoustic, electromagnetic, or optical source). The present invention may equally apply to multiple processes linked by cause and effect that exhibit unequal time dependence. | 03-25-2010 |
S.munir Alam, Durham, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20100285106 | MULTICOMPONENT VACCINE - The present invention relates, in general, to human immunodeficiency virus (HIV) and, in particular, to a multicomponent vaccine and method of using same to protect against HTV-I infection. | 11-11-2010 |
S. Munir Alam, Durham, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090317419 | Tetramers - The present invention relates, in general to human immunodeficiency virus (HIV), and, in particular, to B cell tetramers and to methods of using same for diagnosis, disease monitoring and vaccine development. | 12-24-2009 |
| 20100028415 | Method of Inducing Neutralizing Antibodies to Human Immunodeficiency Virus - The present invention relates, in general, to human immunodeficiency virus (HIV), and, in particular, to a method of inducing neutralizing antibodies to HIV and to compounds and compositions suitable for use in such a method. | 02-04-2010 |
| 20100047331 | METHOD OF INDUCING NEUTRALIZING ANTIBODIES TO HUMAN IMMUNODEFICIENCY VIRUS - The present invention relates, in general, to human immunodeficiency virus (HIV), and, in particular, to a method of inducing neutralizing antibodies to HIV and to compounds and compositions suitable for use in such a method. | 02-25-2010 |
| 20120070488 | METHOD OF INDUCING NEUTRALIZING ANTIBODIES TO HUMAN IMMUNODEFICIENCY VIRUS - The present invention relates, in general, to human immunodeficiency virus (HIV), and, in particular, to a method of inducing neutralizing antibodies to HIV and to compounds and compositions suitable for use in such a method. | 03-22-2012 |
| 20120128758 | FORMULATION FOR INDUCING BROADLY REACTIVE NEUTRALIZING ANTI-HIV ANTIBODIES - The present invention relates in general, to a formulation suitable for use in inducing anti-HIV-1 antibodies, and, in particular, to a formulation comprising Toll Like Receptor (TLR) agonists with HIV-1 gp41 membrane proximal external region (MPER) peptide-liposome conjugates for induction of broadly reactive anti-HIV-1 antibodies. The invention also relates to methods of inducing neutralizing anti-HIV-1 antibodies using such formulations. | 05-24-2012 |
| 20120177721 | FORMULATION - The present invention relates, in general, to a formulation suitable for use in inducing anti-HIV-1 antibodies and, in particular, to a formulation comprising a prehairpin intermediate form of HIV-1 envelope gp41 linked to a liposome. The invention also relates to methods of inducing broadly neutralizing anti-HIV-1 antibodies using such a formulation. | 07-12-2012 |
| 20120183597 | Method of inducing neutralizing antibodies to human immunodeficiency virus - The present invention relates, in general, to human immunodeficiency virus (HIV), and, in particular, to a method of inducing neutralizing antibodies to HIV and to compounds and compositions suitable for use in such a method. | 07-19-2012 |
Syed M. Alam, Austin, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20090086524 | PROGRAMMABLE ROM USING TWO BONDED STRATA AND METHOD OF OPERATION - A read only memory implemented as a 3D integrated device has a first stratum, a second stratum, and bonded inter-strata connections for coupling the first stratum to the second stratum. The physical bonding between the two strata implements the programming of the read only memory. The stratum may be in wafer form or in die form. The first stratum includes functional active devices and at least one non-programmed active device. The second stratum includes at least conductive routing to be associated with the at least one non-programmed active device. The bonded inter-strata connections include at least one bonded programmable inter-strata connection for programming the at least one non-programmed active device and for providing conductive routing to the programmed active device. The two strata thus form a programmed ROM. Other types of programmable storage devices may be implemented by bonding the two strata. | 04-02-2009 |
| 20120155160 | MEMORY CONTROLLER AND METHOD FOR INTERLEAVING DRAM AND MRAM ACCESSES - A memory controller and method for interleaving volatile and non-volatile memory different latencies and page sizes are described wherein a single DDR3 memory controller communicates with a number of memory modules comprising of at least non-volatile memory, e.g., spin torque magnetic random access memory, integrated in a different Rank or Channel with a volatile memory, e.g., dynamic random access memory (DRAM). | 06-21-2012 |
| 20120195112 | METHOD OF WRITING TO A SPIN TORQUE MAGNETIC RANDOM ACCESS MEMORY - A method includes destructively reading bits of a spin torque magnetic random access memory and immediately writing back the original or inverted values. A detection of the majority state of the write back bits and a conditional inversion of write back bits are employed to reduce the number of write back pulses. A subsequent write command received within a specified time or before an original write operation is commenced will cause a portion of the write back pulses or the original write operation pulses to abort. Write pulses during subsequent write operations will follow the conditional inversion determined for the write back bits during destructive read. | 08-02-2012 |
| 20120198313 | METHOD OF READING AND WRITING TO A SPIN TORQUE MAGNETIC RANDOM ACCESS MEMORY WITH ERROR CORRECTING CODE - A method includes destructively reading bits of a spin torque magnetic random access memory, using error correcting code (ECC) for error correction, and storing inverted or non-inverted data in data-store latches. When a subsequent write operation changes the state of data-store latches, parity calculation and majority detection of the bits are initiated. A majority bit detection and potential inversion of write data minimizes the number of write current pulses. A subsequent write operation received within a specified time or before an original write operation is commenced will cause the majority detection operation to abort. | 08-02-2012 |
| 20120311396 | MRAM FIELD DISTURB DETECTION AND RECOVERY - A method and memory device is provided for reading data from an ECC word of a plurality of reference bits associated with a plurality of memory device bits and determining if a double bit error in the ECC word exists. The ECC word may be first toggled twice and the reference bits reset upon detecting the double bit error. | 12-06-2012 |
Tausif Alam, Madison, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20120315255 | Hepatocyte Based Insulin Gene Therapy For Diabetes - A method and vectors for controlling blood glucose levels in a mammal are disclosed. In one embodiment, the method comprises the steps of: treating the hepatocyte cells of a patient with a first, second or third vector, wherein the first vector comprises a promoter enhancer, glucose inducible regulatory elements, a liver-specific promoter, a gene encoding human insulin with modified peptidase and an albumin 3′UTR and lacks an HGH intron, wherein the second vector comprises an HGH intron, glucose inducible regulatory elements, a liver-specific promoter, a gene encoding human insulin with modified peptidase site and an albumin 3′UTR and lacks a promoter enhancer, wherein the third vector comprises an HGH intron, glucose inducible regulatory elements, a liver-specific promoter, a gene encoding human insulin with modified peptidase site, an albumin 3′UTR and a promoter enhancer and observing the patient's insulin levels, wherein the patient's insulin levels are controlled. | 12-13-2012 |
Todd M. Alam, Cedar Crest, NM US
| Patent application number | Description | Published |
|---|---|---|
| 20080204022 | Biological detector and method - A biological detector includes a conduit for receiving a fluid containing one or more magnetic nanoparticle-labeled, biological objects to be detected and one or more permanent magnets or electromagnet for establishing a low magnetic field in which the conduit is disposed. A microcoil is disposed proximate the conduit for energization at a frequency that permits detection by NMR spectroscopy of whether the one or more magnetically-labeled biological objects is/are present in the fluid. | 08-28-2008 |
| 20100219824 | BIOLOGICAL DETECTOR AND METHOD - A biological detector includes a conduit for receiving a fluid containing one or more magnetic nanoparticle-labeled, biological objects to be detected and one or more permanent magnets or electromagnet for establishing a low magnetic field in which the conduit is disposed. A microcoil is disposed proximate the conduit for energization at a frequency that permits detection by NMR spectroscopy of whether the one or more magnetically-labeled biological objects is/are present in the fluid. | 09-02-2010 |