| Patent application number | Description | Published |
|---|
| 20100185397 | METHOD FOR IDENTIFYING NUCLEOTIDE SEQUENCE, METHOD FOR ACQUIRING SECONDARY STRUCTURE OF NUCLEIC ACID MOLECULE, APPARATUS FOR IDENTIFYING NUCLEOTIDE SEQUENCE, APPARATUS FOR ACQUIRING SECONDARY STRUCTURE OF NUCLEIC ACID MOLECULE, PROGRAM FOR IDENTIFYING NUCLEOTIDE SEQUENCE, AND PROGRAM FOR ACQUIRING SECONDARY STRUCTURE OF NUCLEIC ACID MOLECULE - It is intended to provide a method for identifying a nucleotide sequence necessary for expressing an affinity for a target substance in nucleotide sequences of nucleic acid molecules such as aptamers having the affinity for the target substance based on a homology of the respective nucleotide sequences and an evaluation value related to the affinity of the nucleotide sequences, and a method for predicting a secondary structure of a nucleic acid molecule containing the identified nucleotide sequence. The method for identifying a nucleotide sequence necessary for expressing an affinity for a target substance in nucleotide sequences of nucleic acid molecules having such an affinity is characterized by comprising the steps of: extracting a single-strand region from the nucleotide sequences of nucleic acid molecules by excluding nucleotides capable of forming a stem structure; and searching a motif sequence based on an evaluation value of the affinity from the single-strand region. | 07-22-2010 |
| 20100216650 | METHOD OF PREDICTING NUCLEIC ACID HIGHER-ORDER STRUCTURE, APPARATUS FOR PREDICTING NUCLEIC ACID HIGHER-ORDER STRUCTURE, AND PROGRAM FOR PREDICTING NUCLEIC ACID HIGHER-ORDER STRUCTURE - The object of the present invention is to provide a method of predicting a higher-order structure of a nucleic acid sequence typified by a G quartet structure, and an apparatus and a program that execute the method. The method according to the present invention relates to a method of predicting a nucleic acid higher-order structure that predicts a higher-order structure of a nucleic acid sequence, the method, including the steps of: extracting bases capable of forming a higher-order structure as a higher-order structure candidate from said nucleic acid sequence; extracting bases capable of forming a stem structure as a stem structure candidate from said nucleic acid sequence; and searching an optimal combinatorial structure based on the higher-order structure candidate and the stem structure candidate. | 08-26-2010 |
| 20110125681 | FEATURE EXTRACTION METHOD, FEATURE EXTRACTION APPARATUS, AND FEATURE EXTRACTION PROGRAM - Provided are a feature extraction method of creating a feature vector for objectively evaluating the sequence of aptamer on the basis of the biological features and a feature extraction apparatus and a feature extraction program for performing the method. The feature extraction method according to the present invention includes a step of predicting a secondary structure of a base sequence applied and a step of creating a feature vector based on a predicted secondary structure of the sequence. | 05-26-2011 |
| 20120003749 | NUCLEIC ACID MOLECULE CAPABLE OF BINDING TO 2,4,6-TRINITROPHENYL SKELETON, METHOD FOR DETECTING COMPOUND HAVING 2,4,6-TRINITROPHENYL SKELETON USING THE NUCLEIC ACID MOLECULE, AND USE OF THE NUCLEIC ACID MOLECULE - The present invention relates to a nucleic acid molecule capable of binding to a 2,4,6-trinitrophenyl skeleton, a method for detecting a compound having the 2,4,6-trinitrophenyl skeleton using the nucleic acid molecule, use of the nucleic acid molecule for detecting a compound having the 2,4,6-trinitrophenyl skeleton, and a method for detecting a compound having the 2,4,6-trinitrophenyl skeleton. | 01-05-2012 |
