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Akira Imaizumi

Akira Imaizumi, Kanagawa JP

Patent application numberDescriptionPublished
20100009402METHOD OF EVALUATING BREAST CANCER, BREAST CANCER-EVALUATING APPARATUS, BREAST CANCER-EVALUATING METHOD, BREAST CANCER-EVALUATING SYSTEM, BREAST CANCER-EVALUATING PROGRAM AND RECORDING MEDIUM - According to the method of evaluating breast cancer of the present invention, amino acid concentration data on the concentration value of amino acid in blood collected from a subject to be evaluated is measured, and a breast cancer state in the subject is evaluated based on the concentration value of at least one of Ser, Gln, Val, Cys, Orn, Arg, Ile and ABA contained in the measured amino acid concentration data of the subject.01-14-2010
20100017144Lung cancer evaluating apparatus, method, system, and program and recording medium therefor - According to the method of evaluating lung cancer, amino acid concentration data on the concentration value of amino acid in blood collected from a subject to be evaluated is measured, and a lung cancer state in the subject is evaluated based on the concentration value of at least one of Orn, Lys, ABA, Arg, Glu, His, Tau, Pro, Ala, Cit and Ile contained in the measured amino acid concentration data of the subject.01-21-2010
20100017145METHOD OF EVALUATING CANCER STATE, CANCER-EVALUATING APPARATUS, CANCER-EVALUATING METHOD, CANCER-EVALUATING SYSTEM, CANCER-EVALUATING PROGRAM AND RECORDING MEDIUM - According to the method of evaluating cancer state of the present invention, amino acid concentration data on the concentration value of amino acid in blood collected from a subject to be evaluated is measured, and a cancer state in the subject is evaluated based on the concentration value of at least one of Cys, Gln, Trp, Orn, Arg, Glu, His, Ser and ABA contained in the measured amino acid concentration data of the subject.01-21-2010
20110024911SEMICONDUCTOR DEVICE AND METHOD FOR MANUFACTURING THE SAME - An electrical characteristics test for a semiconductor integrated circuit using a Kelvin contact method can be conducted in a pre-process without obstructing the reduction in size of a semiconductor chip or without complicating the circuit design. A probe card in a testing apparatus includes probes for Kelvin contact, the probes for Kelvin contact including a coil probe and a POGO pin probe disposed inside the coil probe, and a probe for two-terminal measurement. Electrode pads formed in each chip area over a wafer are in a relation of A=B<2A, given that the area of one of the electrode pads with which the probe for Kelvin contact comes into contact is B and the area of the other electrode pad with which the probe for two-terminal measurement comes into contact is A.02-03-2011
20110035156Method of evaluating gastric cancer, gastric cancer-evaluating apparatus, gastric cancer-evaluating method, gastric cancer-evaluating system, gastric cancer-evaluating program and recording medium - According to the method of evaluating gastric cancer of the present invention, amino acid concentration data on the concentration value of amino acid in blood collected from a subject to be evaluated is measured, and a gastric cancer state in the subject is evaluated based on the concentration value of at least one of Asn, Cys, His, Met, Orn, Phe, Trp, Pro, Lys, Leu, Glu, Arg, Ala, Thr, and Tyr contained in the measured amino acid concentration data of the subject.02-10-2011
20110091924Method of evaluating cancer type - According to the method of evaluating cancer type of the present invention, amino acid concentration data on concentration values of amino acids in blood collected from a subject to be evaluated is measured, and the cancer type in the subject is evaluated based on the concentration value of at least one of Glu, ABA, Val, Met, Pro, Phe, Thr, Ile, Leu, and His contained in the measured amino acid concentration data of the subject.04-21-2011
20110138889Method of evaluating prostatic disease - According to the method of evaluating prostatic disease of the present invention, amino acid concentration data on concentration values of amino acids in blood collected from a subject to be evaluated is measured, and the state of prostatic disease including at least one of prostatic cancer and prostatic hypertrophy in the subject is evaluated based on the concentration value of at least one of Tau, Thr, Ser, Asn, Glu, Pro, Gly, Ala, Cit, ABA, Val, Met, Ile, Leu, Phe, His, Trp, Orn, Lys, and Cys2 contained in the measured amino acid concentration data of the subject.06-16-2011
20110143444METHOD OF EVALUATING FEMALE GENITAL CANCER - According to the method of evaluating female genital cancer of the present invention, amino acid concentration data on concentration values of amino acids in blood collected from a subject to be evaluated is measured, and the state of female genital cancer including at least one of cervical cancer, endometrial cancer, and ovarian cancer in the subject is evaluated based on the concentration value of at least one of Thr, Ser, Asn, Gln, Pro, Gly, Ala, Cit, Val, Met, Ile, Leu, Tyr, Phe, His, Trp, Orn, Lys, and Arg contained in the measured amino acid concentration data of the subject.06-16-2011

Akira Imaizumi, Kawasaki-Shi JP

Patent application numberDescriptionPublished
20090246835 L-AMINO ACID-PRODUCING BACTERIUM AND A METHOD FOR PRODUCING AN L-AMINO ACID - An L-amino acid is produced by culturing a microorganism of the family Enterobacteriaceae which has the ability to produce an L-amino acid and which has been modified so as to increase the expression of the evgA gene, the gadE gene, and/or the ydeO gene. These genes encode a transcription factor involved in the EvgAS two-component system regulon. The culture takes place in a medium, and the L-amino acid is collected from the medium or cells.10-01-2009
20100009401METHOD OF EVALUATING COLORECTAL CANCER, COLORECTAL CANCER-EVALUATING APPARATUS, COLORECTAL CANCER-EVALUATING METHOD, COLORECTAL CANCER-EVALUATING SYSTEM, COLORECTAL CANCER-EVALUATING PROGRAM AND RECORDING MEDIUM - According to the method of evaluating colorectal cancer of the present invention, amino acid concentration data on the concentration value of amino acid in blood collected from a subject to be evaluated is measured, and a colorectal cancer state in the subject is evaluated based on the concentration value of at least one of Arg, Cys, Orn, Trp, Glu, ABA, Val, Phe, Leu, Gln, Ile and His contained in the measured amino acid concentration data of the subject.01-14-2010
20100184162METHOD FOR PRODUCTION OF AN L-AMINO ACID - A method is provided for producing an L-amino acid by culturing a microorganism belonging to the Enterobacteriaceae family and having the ability to produce an L-amino acid, in a medium to produce and accumulate the L-amino acid in the medium. The microorganism has been modified by introduction of a DNA fragment which includes a pho regulon promoter and a structural gene encoding an L-amino acid biosynthetic enzyme, which is ligated downstream of the promoter so that the gene is expressed by the promoter, and so that the activity of the L-amino acid biosynthetic enzyme is increased by the expression of the gene by the promoter. In this way, the L-amino acid that is produced in the medium can be collected. Furthermore, the phosphorus concentration in the medium is such that the expression of the gene by the promoter is induced.07-22-2010

Patent applications by Akira Imaizumi, Kawasaki-Shi JP

Akira Imaizumi, Tokyo JP

Patent application numberDescriptionPublished
20100092445Adoptive immune cells for tumor vaccines - Adoptive immune cells obtained by a method including (a) obtaining mammalian antigen-presenting associated cells; (b) culturing the resulting cells from step (a) in a culture liquid contained in a culture vessel coated with a sugar chain-containing polymer; and (c) detaching the cells from step (b) by shaking the culture vessel without treating the cells with an enzyme and without using a cell detaching tool. A method for treating a malignant tumor, type I diabetes, an atopic allergic disease or an infection, by administering the adoptive immune cells to a patient. A pharmaceutical composition for treating a malignant tumor, type I diabetes, an atopic allergic disease or an infection, including the adoptive immune cells and a pharmaceutically acceptable carrier.04-15-2010