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Akashi, Osaka

Hiroki Akashi, Osaka JP

Patent application numberDescriptionPublished
20080273354Power Supply - There are provided an inductive load current control circuit for detecting and controlling a current flowing to an inductive load with high accuracy, and a power supply.11-06-2008
20080290851POWER SUPPLY - A power supply has a soft-start function capable of raising its output DC voltage without generating overshoot even when its load condition is set light at the start-up. The power supply comprises an error amplifier for outputting an error signal corresponding to the error between the output DC voltage and the target value thereof, a control section for adjusting power to be supplied to the load on the basis of this error signal, and a limiting circuit for limiting the voltage of the error signal to a predetermined level for a predetermined time after the output DC voltage at the start-up exceeds a predetermined value being set less than the target value.11-27-2008

Patent applications by Hiroki Akashi, Osaka JP

Makoto Akashi, Osaka JP

Patent application numberDescriptionPublished
20090292111ROR-alpha Promoting the Induction of Bmall - An object of the present invention is to clarify unelucidated aspects in the control mechanism of circadian rhythms. The present inventors have newly found that RORα (retinoic acid binding-receptor alpha; the same shall apply hereinafter) stimulates an induction of Bmal1 expression and also that the induction of Bmal1 expression is promoted under hypoxia. These findings strongly suggest the existence of a control mechanism of circadian rhythms that, when RORα expression is promoted under hypoxia or the like, an induction of Bmal1 expression is stimulated and, when the induction of Bmal1 expression is stimulated, binding between BMAL1 and CLOCK is stimulated and an induction of Per gene or Cry gene expression is stimulated. The present invention, therefore, has applicability as jet-lag regulating agents and anticancer agents.11-26-2009

Mitsuru Akashi, Osaka JP

Patent application numberDescriptionPublished
20090092633Polyamino acid for use as adjuvant - Use of a polyamino acid as an adjuvant; an application of a polyamino acid as an adjuvant in the production of a vaccine; a vaccine comprising a polyamino acid as an adjuvant; a biodegradable nanoparticle having a virus antigen immobilized thereon; and a vaccine comprising the biodegradable nanoparticle.04-09-2009
20090117656STIMULI-RESPONSIVE DEGRADABLE GEL - To provide a new reductive-stimuli-responsive degradable gel that allows any control of decomposition of the three-dimensional base material for cell culture and production of a completely biological three-dimensional cellular structure consisting only of cells and cells-produced extracellular matrix and that allows safe recovery of the cellular structure produced.05-07-2009
20090156480Biodegradable nanoparticle having t-cell recognizable epitope peptide immobilized thereon or encapsulated therein - A biodegradable nanoparticle having a T cell recognizable epitope peptide immobilized thereon or encapsulated therein of the present invention is usable as a safe and effective immunotherapeutic agent, and is useful as an immunotherapeutic agent for treating, for example, pollinosis, year-round nasal allergic disease and seasonal nasal allergic disease.06-18-2009
20090285901Polyamino acid for use as adjuvant - Use of a polyamino acid as an adjuvant; an application of a polyamino acid as an adjuvant in the production of a vaccine; a vaccine comprising a polyamino acid as an adjuvant; a biodegradable nanoparticle having a virus antigen immobilized thereon; and a vaccine comprising the biodegradable nanoparticle.11-19-2009
20110046309BIOABSORBABLE MATERIAL AND IN-VIVO INDWELLING DEVICE MADE THEREOF - A bioabsorbable material which is flexible and degradable at a controlled rate, and an in-vivo indwelling device made thereof. The bioabsorbable material is a copolymer composed of an aromatic compound having an α,β-unsaturated carboxylic group and at least one hydroxyl group as substituents on the aromatic ring, and a polycarbonate or a monomer constituting polycarbonate. Alternatively, it is a copolymer composed of, as the first component, an aromatic compound having an α,β-unsaturated carboxylic group and at least one hydroxyl group as substituents on the aromatic ring, as the second component, an aromatic compound having an α,β-unsaturated carboxylic group and at least two hydroxyl groups as substituents on the aromatic ring, and, as the third component, a polycarbonate or a monomer constituting polycarbonate.02-24-2011
20110217726METHOD AND KIT FOR DETECTING BIOLOGICAL SIGNAL OF THREE-DIMENSIONAL CELL CULTURE MATERIAL - Disclosed is a method for detecting a biological signal of a three-dimensional cell culture construct. The method for detecting a biological signal of a three-dimensional cell culture construct includes: providing a three-dimensional cell culture construct that contains at least two cell layers laminated to each other and a sensor particle capable of detecting a biological signal; and observing the sensor particle optically. Preferably, the three-dimensional cell culture construct contains an extracellular matrix including a combination of a protein or polymer having an RGD sequence and a protein or polymer that interacts with the protein or polymer having the RGD sequence, or a combination of a protein or polymer that is positively charged and a protein or polymer that is negatively charged.09-08-2011
20110257338HYDROPHILIC MATERIAL, MEDICAL MATERIAL AND SUSTAINED DRUG RELEASE MATERIAL - A hydrophilic material having a hydrophilic nature and being biocompatible and processable into nanoparticles wherein a hydrophilic monomer such as threitol or a hydrophilic polymer such as polyethylene glycol is attached to the βposition of an α, β-unsaturated carboxyl group of a (co)polymer comprising an aromatic compound such as 4-hydroxycinnamic acid in which an aromatic ring is substituted by the α, β-unsaturated carboxyl group and one or more hydroxyl groups. In particular, a hydrophilic material having a nanoparticle size which is highly dispersible in water, can well migrate into the blood and is useful as a drug carrier, a medical material and a sustained drug release material.10-20-2011

Patent applications by Mitsuru Akashi, Osaka JP

Taikoh Akashi, Osaka JP

Patent application numberDescriptionPublished
20110293122DISPLAY SYSTEM, DISPLAY CONTROL METHOD AND COMPUTER PROGRAM - It is expected to provide a display system, display control method and computer program for effectively outputting sound with plural display apparatuses in a two dimensional array.12-01-2011