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Airenne, FI
Kari Airenne, Kuopio FI
| Patent application number | Description | Published |
|---|---|---|
| 20090011509 | INTEGRASE FUSION PROTEINS AND THEIR USE WITH INTEGRATING GENE THERAPY - In a method of targeting intergration of a transgene comprising retrovirus-like DNA into a eukaryotic genome, the genome is cleared by an endonuclease and the transgene is introduced at the site of cleavage, wherein the endonuclease is specific to a site in an abundant rDNA locus and is fused to an integrase that mediates the introduction of the transgene. The fusion protein may be new. | 01-08-2009 |
| 20090011984 | Biotin-binding receptor molecules - The subject invention pertains to a transmembrane protein capable of binding to biotinylated molecules, the protein comprising a cytoplasmic domain, a membrane-spanning domain and an extracellular domain, wherein the extracellular domain comprises biotin-binding activity, and methods of use. The protein can be expressed in a cell, thereby targeting a biotinylated drug. | 01-08-2009 |
Kari J. Airenne, Kuopio FI
| Patent application number | Description | Published |
|---|---|---|
| 20100003746 | Production of Lentiviral Vectors - The present invention is a method of generating a lentivirus vector, comprising cloning each of a leotivimus transfer construct, gag, pol, an envelope protein and rev respectively into the same or different baculoviruses, and transducing a producer cell with the or each baculovirus. | 01-07-2010 |
Kari Juhani Airenne, Kuopio FI
| Patent application number | Description | Published |
|---|---|---|
| 20080280363 | Pseudotyped Baculovirus and its Use - A viral G protein-pseudotyped baculovirus, in which the G protein is truncated and comprises the ectodomain, transmembrane domain and cytoplasmic tail domain. Such a baculovirus can be used for transduction of cells and for gene therapy. | 11-13-2008 |
| 20080280783 | Baculovirus-Based Gene Libraries - A nucleotide molecule comprising a selectable gene flanked by anL1 and anL2 attachment sites of a bacteriophage and additionally comprising an origin of replication. This can be used to create a baculovirus-based gene library. | 11-13-2008 |
| 20090047733 | Avidin-Pseudotyped Viral Vectors and Their Use - The present invention pertains to an avidin-pseudotyped virus, and especially baculovirus, useful for delivery of foreign genes etc. The present invention also pertains to vectors comprising respective cassettes for pseudotyping, mammalian gene expression and insect gene expression in baculovirus. | 02-19-2009 |
| 20090176660 | Engineered Baculoviruses and Their Use - Baculovirus is engineered so that the capsid displays one or more heterologous peptides or protein. Such baculovirus can be used to deliver therapeutics, and in functional genomics. | 07-09-2009 |
| 20110144013 | VEGF-D Mutants and Their Use - The present invention is a VEGF-D protein, containing one or more amino acid mutations at the dimer interface, and their use in therapy, particularly in the promotion of angiogenesis. | 06-16-2011 |
Tomi Airenne, Turku FI
| Patent application number | Description | Published |
|---|---|---|
| 20110021760 | CRYSTALLINE VAP-1 AND USES THEREOF - The present invention relates to crystalline vascular adhesion protein-1 (VAP-1) and in particular to methods for the use of structural information of crystalline human VAP-1 for ligand and/or inhibitor identification, design and production, as well as screening assays for detections of same. The invention further relates to inhibitors identified by the assays according to the present invention. | 01-27-2011 |