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Aicher, DE
Alexandra Aicher, Frankfurt DE
| Patent application number | Description | Published |
|---|---|---|
| 20080267927 | Methods for improving cell therapy and tissue regeneration in patients with cardiovascular diseases by means of shockwaves - Improving cell therapy and tissue regeneration in a patient suffering from a cardiovascular or a neurological disease by treating a tissue of the patient with shock waves and/or applying to the patient a therapeutically effective amount of stem cells and/or progenitor cells. Such treatment increases expression of chemoattractants, pro-angiogenic factors, and pro-survival factors. The chemoattractants can be, for example, vascular endothelial growth factor (VEGF) or stromal cell derived factor 1 (SDF-1). For example, the treated tissue can be located in the patient's heart or in a skeletal muscle of the patient, and the shock waves can be extracorporeal shock waves (ESW) or intracorporeal shock waves. The cardiovascular disease can have an ischemic or non-ischemic etiology. For example, the cardiovascular disease can be a myocardial infarction, ischemic cardiomyopathy, or a dilatative cardiomyopathy. For example, the neurological disease can be a peripheral neuropathy or neuropathic pain. | 10-30-2008 |
Andreas Aicher, Muhldorf DE
| Patent application number | Description | Published |
|---|---|---|
| 20100060196 | DEVICE FOR PROTECTING AGAINST PARASITES - The invention relates to a device for protecting against pests, especially in piping systems conveying water, utility lines, and/or ambient air, for example within the water delivery system and/or sewer system of buildings. Said invention enables the inside of a piping system to be illuminated in an energy-saving manner, such that any pests that are normally averse to light will recoil from the light source. | 03-11-2010 |
Babette Aicher, Voerde DE
| Patent application number | Description | Published |
|---|---|---|
| 20100056548 | THIENOPYRIMIDINES HAVING MNK1/MNK2 INHIBITING ACTIVITY FOR PHARMACEUTICAL COMPOSITIONS - The present invention relates to novel pharmaceutical compositions comprising thienopyrimidine compounds. Moreover, the present invention relates to the use of the thienopyrimidine compounds of the invention for the production of pharmaceutical compositions for the prophylaxis and/or treatment of diseases which can be influenced by the inhibition of the kinase activity of Mnk1 and/or Mnk2 (Mnk2a or Mnk2b) and/or variants thereof. | 03-04-2010 |
Babette Aicher, Gottingen DE
| Patent application number | Description | Published |
|---|---|---|
| 20080207594 | Use of Gsk-3 Inhibitors for Preventing and Treating Pancreatic Autoimmune Disorders - This invention relates to the use of Pax4 stimulating compounds, e.g. Glycogen synthase kinase-3 (GSK-3) inhibitors, particularly in combination with immunomodulating agents, in the prevention, and/or treatment of pancreatic autoimmune disorders, e.g. type I diabetes or LADA. More particularly, this invention relates to the use of compounds selected from paullones, indirubines, substituted ureas, maleimide derivatives and pyrimidine thiones. Further, the present invention relates to a method of identifying and/or characterizing pancreatic beta-cell mitogens by using cells expressing a pancreatic gene or a gene whose function is controlled by a pancreatic gene, particularly the Pax4 gene, and which are transfected with a reporter gene. | 08-28-2008 |
| 20090163520 | MNK1 or MNK2 Inhibitors - The present invention relates to the use of pyrazolopyrimidine compounds for the production of pharmaceutical compositions for the prophylaxis and/or treatment of diseases which can be influenced by the inhibition of the kinase activity of Mnk1 and/or Mnk2 (Mnk2a or Mnk2b) and/or variants thereof. | 06-25-2009 |
Babette Aicher, Goettingen DE
| Patent application number | Description | Published |
|---|---|---|
| 20090069323 | 11beta-hsdi inhibitors - The invention relates to compounds of formula (I) | 03-12-2009 |
Babette Aicher, Frankfurt Am Main DE
| Patent application number | Description | Published |
|---|---|---|
| 20100143341 | THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS - The present invention relates to novel pharmaceutical compositions of general formula (I) comprising thienopyrimidine compounds. Moreover, the present invention relates to the use of the thienopyrimidine compounds of the invention for the production of pharmaceutical compositions for the prophylaxis and/or treatment of diseases which can be influenced by the inhibition of the kinase activity of Mnk1 and/or Mnk2 (Mnk2a or Mnk2b) and/or variants thereof. | 06-10-2010 |
| 20110028421 | Use of alkylphosphocholines in combination with antimetabolites for the treatment of benign and malignant oncoses in humans and mammals - The invention relates to the use of alkylphosphocholines in combination with antimetabolites for the treatment of multiple myeloma, colon cancer or renal cancer. Preferred alkylphosphocholines are described by the Formula II. | 02-03-2011 |
| 20120083494 | NOVEL TRIAZOLE DERIVATIVES WITH IMPROVED RECEPTOR ACTIVITY AND BIOAVAILABILITY PROPERTIES AS GHRELIN ANTAGONISTS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS - The present invention provides novel triazole derivatives with improved receptor activity and bioavailability properties as ghrelin analogue ligands of growth hormone secretagogue receptors according to formula (I) that are useful in the treatment or prophylaxis of physiological and/or pathophysiological conditions in mammals, preferably humans, that are mediated by GHS receptors. The present invention further provides GHS receptor antagonists and agonists that can be used for modulation of these receptors and are useful for treating above conditions, in particular alcohol disorder, drug abuse, growth retardation, cachexia, short-, medium-, and/or long term regulation of energy balance, short-, medium-, and/or long term regulation (stimulation and/or inhibition) of food intake, intake of rewarding food, adipogenesis, adiposity and/or obesity, body weight gain and/or reduction, diabetes, diabetes type I, diabetes type II, tumor cell proliferation, inflammation, inflammatory effects, gastric postoperative ileus, postoperative ileus and/or gastrectomy (ghrelin replacement therapy). | 04-05-2012 |
Babette Aicher, Frankfurt DE
| Patent application number | Description | Published |
|---|---|---|
| 20100234377 | PIPERAZINE COMPOUNDS FOR THE INHIBITION OF HAEMATOPOIETIC PROSTAGLANDIN D SYNTHASE - The present invention relates to compounds of general formula (I): | 09-16-2010 |
Daniel Aicher, Berlin DE
| Patent application number | Description | Published |
|---|---|---|
| 20110206613 | METHOD AND APPLICATION OF UNSYMMETRICALLY meso-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT - Biologically active compounds are provided that can be used as photosensitizers for diagnostic and therapeutic applications, particularly for PDT of cancer, infections and other hyperproliferative diseases, fluorescence diagnosis and PDT treatment of a non-tumorous indication such as arthritis, inflammatory diseases, viral or bacterial infections, dermatological, ophthalmological or urological disorders as well as providing methods to obtain them in pharmaceutical quality. One embodiment consists of a method to synthesize a porphyrin with a defined arrangement of meso-substituents and then converting this porphyrin system to a chlorin system by dihydroxylation or reduction, and if more than one isomer is formed separate them by chromatography either on normal or reversed phase silica. In another embodiment the substituents on the porphyrin are selected to direct the reduction or dihydroxylation to the chlorin so that a certain isomer is selectively formed. Another embodiment is to provide amphiphilic compounds with a higher membrane affinity and increased PDT-efficacy. In another embodiment a method to reductively cleave the osmate(VI)ester avoiding the use of gaseous H | 08-25-2011 |
| 20120263625 | GLYCO-SUBSTITUTED DIHYDROXY-CHLORINS AND -FUNCTIONALIZED CHLORINS FOR ANTI-MICROBIAL PHOTODYNAMIC THERAPY - Antimicrobial molecular conjugates for the treatment and prevention of infectious diseases caused by pathogenic microorganisms in human and animals are provided. The key to these conjugates is connecting dihydroxychlorins or β-functionalized chlorins to carbohydrate moieties. These conjugates are found to be very effective in combating bacterial infections caused by Gram-positive and Gram-negative bacteria, including their resistant strains. Significantly, they are also effective in complex environments, including blood, serum, and other body fluids which are present in patient's body. A method of use to control pathogenic microorganisms in human and animals is also provided. | 10-18-2012 |
Jochen Aicher, Rietheim-Weilheim DE
| Patent application number | Description | Published |
|---|---|---|
| 20090219034 | Diagnostic Circuit and Method of Testing a Circuit - A diagnostic circuit is configured for connecting to a unit under test that has a load and a sinusoidal source. The diagnostic circuit includes a voltage sensing device that has an input for sensing a signal, a first terminal for connecting to the load, a second terminal for connecting to the sinusoidal source, and a relay connected between the first and second terminals for connecting the sinusoidal source to the load. Clamping diodes are provide for clamping a sinusoidal signal and include a first clamping diode connected between a D/C voltage source and the input and a second clamping diode connected between ground and the input. A resistor is connected between the D/C voltage source and the first terminal. The diagnostic circuit verifies the operational functionality of the load, related wiring and connections. | 09-03-2009 |
| 20110248722 | Diagnostic Circuit and Method of Testing a Circuit - A diagnostic circuit is configured for connecting to a unit under test that has a load and a sinusoidal source. The diagnostic circuit includes a voltage sensing device that has an input for sensing a signal, a first terminal for connecting to the load, a second terminal for connecting to the sinusoidal source, and a relay connected between the first and second terminals for connecting the sinusoidal source to the load. Clamping diodes are provide for clamping a sinusoidal signal and include a first clamping diode connected between a D/C voltage source and the input and a second clamping diode connected between ground and the input. A resistor is connected between the D/C voltage source and the first terminal. The diagnostic circuit verifies the operational functionality of the load, related wiring and connections. | 10-13-2011 |
Max Aicher, Freilassing DE
| Patent application number | Description | Published |
|---|---|---|
| 20110114820 | FORMWORK TIE ROD - A formwork tie rod ( | 05-19-2011 |
Maximilian Aicher, Freilassing DE
| Patent application number | Description | Published |
|---|---|---|
| 20110262246 | Threaded Rod - A threaded rod comprises a single coarse thread having flattenings on opposite sides forming thread sections on opposite sides. At least one of the thread sections on one side of the threaded rod is omitted. | 10-27-2011 |
Thomas Aicher, Badenweiler DE
| Patent application number | Description | Published |
|---|---|---|
| 20080229662 | METHOD FOR VAPORISING AND REFORMING LIQUID FUELS - The invention relates to a method for vaporising and reforming liquid fuels, in particular the catalytic and non-catalytic partial oxidation and the autothermal reforming of liquid fuels with the addition of air- or air-vapour mixtures or air-water mixtures. The invention thereby solves the problems of the mixture formation, soot formation and conversion into low hydrocarbons and hydrogen in conjunction with reforming methods known from the state of the art. | 09-25-2008 |
Thomas Aicher, Munchen DE
| Patent application number | Description | Published |
|---|---|---|
| 20120294219 | METHOD AND APPARATUS FOR MOBILE MARKET SERVICE TRANSACTIONS - An approach is provided for receiving a request to broadcast at least one message associated with one or more market transactions. The approach further involves causing, at least in part, a conversion of the at least one message to a format for embedding into at least one broadcast signal. The approach also causes, at least in part, a transmission of the at least one converted message via the at least one broadcast signal. | 11-22-2012 |
Wilhelm Karl Aicher, Ammerbuch DE
| Patent application number | Description | Published |
|---|---|---|
| 20110238180 | CARTILAGE REPLACEMENT IMPLANT AND METHOD FOR PRODUCING A CARTILAGE REPLACEMENT IMPLANT - To improve a cartilage replacement implant for the biological regeneration of a damaged cartilage area of articular cartilage in the human body, comprising a cell carrier which has a defect-contacting surface for placement on the damaged cartilage area and is formed and designed for colonization with human cells, so that after implantation of the cartilage replacement implant, formation of a gap between adjacent contact surfaces of the implant and surrounding recipient tissue is minimized, it is proposed that the cell carrier rest with surface-to-surface contact on a carrier and be joined to the carrier at a cell carrier surface that faces away from the defect-contacting surface. A method for producing a cartilage replacement implant is also proposed. | 09-29-2011 |