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| 20090030021 | Quinazoline Derivatives and Therapeutic Use Thereof - Quinazoline derivatives represented by the general formula | 01-29-2009 |
| 20090270358 | PHARMACEUTICAL FORMULATION OF CLAVULANIC ACID - The present invention generally relates to stable pharmaceutical compositions, and methods of making and administering such compositions. In one aspect, the invention features stabilized pharmaceutical compositions that include pharmaceutically active ingredients such as potassium clavulanate or Clavitesse™, preferably in an immediate-release solid dosage form or an extended-release solid dosage form. Also provided are methods for making and using such immediate-release and stabilized compositions or extended-release and stabilized compositions. | 10-29-2009 |
| 20100099644 | HPMA - DOCETAXEL OR GEMCITABINE CONJUGATES AND USES THEREFORE - Disclosed are water-soluble compositions of gemcitabine and docetaxel formed by conjugating the gemcitabine or docetaxel to a water-soluble polymer such as N-2-hydroxypropyl methacrylamide (HPMA). Also disclosed are methods of using the compositions of the invention for the treatment of cancer. | 04-22-2010 |
| 20100255099 | CLAVULANATE FORMULATION FOR NEUROPROTECTION AND TREATMENT OF NEURODEGENERATIVE DISORDERS - The present invention generally relates to use of a stable solid pharmaceutical compositions that includes a clavulanate as the pharmaceutically active ingredients in an immediate-release or an extended-release solid dosage form. The composition can be used in a method of treating a neurodegenerative disease, providing neuroprotection, or preventing neuronal cell loss or death. Exemplary neurodegenerative diseases include Parkinson's disease, Alzheimer's disease and multiple sclerosis. | 10-07-2010 |
| 20120029012 | 5, 6, or 7-SUBSTITUTED -3-(HETERO) ARYLISOQUINOLINAMINE DERIVATIVES AND THERAPEUTIC USE THEREOF - The present invention relates to 5, 6, or 7-substituted-3-(hetero)arylisoquinolinamine derivatives represented by general formula D, their pharmacologically acceptable salts thereof, and compositions containing such compounds. Methods for treating hyperproliferative disorders by administering the compounds are also included. | 02-02-2012 |
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| 20090152215 | ON-CHIP SAMPLE PREPARATION FOR WHOLE BLOOD ANALYSIS - A novel filter-less separation technique for separating suspended particles from a solution is disclosed. More specifically, an on-chip bioparticle separator is disclosed, which relies on the differential force exerted by application of a series of high magnitude, short duration pressure pulses on bioparticles in suspension within microchannels, resulting in separation of suspended bioparticles. The filter-less separation technique is inherently suited to μTAS (Micro Total Analysis System) since it exploits uniquely microscale phenomena to achieve separation. The on-chip bioparticle separator can be easily integrated with a disposable biochip, can be fabricated using low-cost, rapid manufacturing techniques, and can provide high performance for separation of bioparticles without the use of specialized or expensive equipment. Embodiments of the present invention address a significant challenge in the development of disposable microfluidic biochips, specifically, providing a reliable solution for separating bioparticles in a microfluidic system that may be immediately applied for a variety of microfluidic biochip applications. | 06-18-2009 |
| 20090297574 | FLEXABLE SPIRALLY-ROLLED POLYMER TUBE FOR MONITORING AND TREATMENT OF BRAIN INJURIES - A flexible spirally-rolled polymer microtube for in vivo monitoring and treatment of brain injuries; the tube integrally comprising one or more microsensors and one or more microchannels, wherein the microsensors monitor one or more parameters and the microchannels are capable of delivering substances to the brain, removing substances from the brain, or both. | 12-03-2009 |
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| 20100265251 | Virtual Endoscopy with Improved Image Segmentation and Lesion Detection - A system, and computer implemented method are provided for interactively displaying three-dimensional structures. Three-dimensional volume data ( | 10-21-2010 |
| 20110055916 | METHODS, SYSTEMS, AND COMPUTER READABLE MEDIA FOR ADAPTIVE PACKET FILTERING - The subject matter described herein includes methods, systems, and computer readable media for adaptive packet filtering. One method includes identifying at least one subset of rules and an ordered set of firewall packet filtering rules that defines a firewall policy such that the subset contains disjoint rules. Disjoint rules are defined as rules whose order can be changed without changing integrity of the firewall policy. Rules in the subset are sorted to statistically decrease the number of comparisons that will be applied to each packet that a firewall encounters. Packets are filtered at the firewall using the sorted rules in the subset by comparing each packet to each of the sorted rules in the subset until the packet is allowed or denied and ceasing the comparing for the packet in response to the packet being allowed or denied and thereby achieving sub-linear searching for packets filtered using the sorted rules in the subset. | 03-03-2011 |
| 20110135174 | IMAGE REPORTING METHOD AND SYSTEM - A method and system are provided to report the findings of an expert's analysis of image data. The method and system are based on a reporting system that forms the basis of an image management system that can efficiently and systematically generate image reports, facilitate data entry into searchable databases for data mining, and expedite billing and collections for the expert's services. The expert identifies a significant finding on an image and attaches a location:description code to the location of that finding in order to create a significant finding and an entry into a database. Further descriptions of that finding, such as dimensional measurements, may be automatically appended to the finding as secondary attributes. After the evaluation, the system sorts the findings in the database and presents the findings by prioritized categories. The expert edits and approves a multimedia report which may be delivered by electronic means to an end-user. | 06-09-2011 |
| 20120033871 | IMAGE REPORTING METHOD AND SYSTEM - A method and system are provided to report the findings of an expert's analysis of image data. The method and system are based on a reporting system that forms the basis of an image management system that can efficiently and systematically generate image reports, facilitate data entry into searchable databases for data mining, and expedite billing and collections for the expert's services. The expert identifies a significant finding on an image and attaches a location:description code to the location of that finding in order to create a significant finding and an entry into a database. Further descriptions of that finding, such as dimensional measurements, may be automatically appended to the finding as secondary attributes. After the evaluation, the system sorts the findings in the database and presents the findings by prioritized categories. The expert edits and approves a multimedia report which may be delivered by electronic means to an end-user. | 02-09-2012 |
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| 20090111701 | METHOD OF PREPARING A SUBSTRATE WITH A COMPOSITION INCLUDING AN ORGANOBORANE INITIATOR - A method of preparing a substrate with a composition comprising (i) an organoborane initiator and (ii) a radical curable component disposed thereon includes the step of depositing the composition onto the substrate wherein at least one of (i) the organoborane initiator and (ii) the radical curable component is deposited onto the substrate in the form of a gradient pattern. An article comprises the substrate and the gradient pattern formed on the substrate. The gradient pattern is formed from a developed composition comprising the reaction product of (i) the organoborane initiator and (ii) the radical curable component. By forming the gradient pattern on the substrate, combinatorial and high-throughput methods of generating and testing the developed composition are possible, which enable characterization of the developed composition for various physical and chemical properties. | 04-30-2009 |
| 20090306307 | Curable Organosilicon Composition - A curable organosilicon composition includes a radical curable organosilicon compound, an organoborane amine complex, a condensation curable organosilicon compound, a condensation cure catalyst, and a condensation-reactive cross-linking compound. The curable organosilicon composition may further include an amine-reactive compound. A method of forming the curable organosilicon composition introduces the organoborane-amine complex and the amine-reactive compound into separate reaction vessels. The curable organosilicon composition is used to form various articles. | 12-10-2009 |
| 20100221429 | Ambient Lithographic Method Using Organoborane Amine Complexes - A pattern is formed and developed on a surface with an ink system comprising (i) a free radical polymerizable monomer, oligomer or polymer, (ii) an organoborane amine complex, (iii) an amine reactive compound, and (iv) oxygen. Components (i)-(iv) are distributed between an ink and a developing medium. The ink formed on the surface in a pattern is developed by exposure of the ink to the developing medium. Component (iv) may be present as naturally occurring in the air. The method has the advantage of developing polymeric and polymer composite patterns rapidly in ambient air, without heating or irradiation. The ink system can be applied to inorganic and organic surfaces, and is particularly useful for polymeric surfaces such as low energy plastics. The composition can be applied to inorganic and organic surfaces, and is particularly useful for polymeric surfaces such as low energy plastics. | 09-02-2010 |
| 20110060092 | COMPOSITION HAVING IMPROVED ADHERENCE WITH AN ADDITION-CURABLE MATERIAL AND COMPOSITE ARTICLE INCORPORATING THE COMPOSITION - A composition and composite article have improved adherence with an addition-curable material. The composition and therefore the composite article, which includes at least one substrate formed from the composition, include a resin and an additive that is incorporated into the resin. The resin is organic and polymeric and free of ethylenically unsaturated and silicon hydride functional groups. The additive is selected from the group of a fluorine-substituted organopolysiloxane, an amino-functional organopolysiloxane, an unsaturated carboxylic acid or carboxylic acid salt, and combinations thereof. Further, the additive includes a hydrosilylation reactive group present at a surface of the substrate for reaction with the addition-curable material. This improves adherence of the substrate with the addition-curable material. The substrate and the addition-curable material bond together to make the composition article. | 03-10-2011 |
| 20110060099 | COMPOSITION HAVING IMPROVED ADHERENCE WITH AN ADDITION-CURABLE MATERIAL AND COMPOSITE ARTICLE INCORPORATING THE COMPOSITION - A composition and composite article have improved adherence with an addition-curable material. The composition and therefore the composite article, which includes at least one substrate formed from the composition, include a resin and an additive that is incorporated into the resin. The resin is organic and polymeric and free of ethylenically unsaturated and silicon hydride functional groups. The additive is selected from the group of a fluorine-substituted organopolysiloxane, an amino-functional organopolysiloxane, an unsaturated carboxylic acid or carboxylic acid salt, and combinations thereof. Further, the additive includes a hydrosilylation reactive group present at a surface of the substrate for reaction with the addition-curable material. This improves adherence of the substrate with the addition-curable material. The substrate and the addition-curable material bond together to make the composition article. | 03-10-2011 |
| 20110129683 | Radical Polymerizable Composition - A radical polymerizable composition includes a radical polymerizable compound and an organoborane-azole complex. The organoborane-azole complex includes an azole having at least two nitrogen atoms wherein at least one nitrogen atom is an sp | 06-02-2011 |
| 20110135923 | Composite Article - A composite article includes a substrate and a pressure sensitive adhesive (PSA) disposed on the substrate. The PSA includes a polymer formed from at least one radical curable organic compound polymerized in the presence of an organoborane initiator. The polymer has a polydispersity index of less than or equal to 5.0 and a temperature of softening less than a temperature of use. The composite article is formed by a method including the steps of polymerizing the at least one radical curable organic compound to form the polymer and applying the PSA to the substrate to form the composite article. The polymer is formed by a method including the steps of combining the at least one radical curable organic compound and the organoborane initiator and polymerizing the at least one radical curable organic compound. | 06-09-2011 |
| 20110294958 | Method Of Forming A Non-Random Copolymer - A non-random copolymer is formed, and its structure controlled, using a method including the step of combining a mixture of a first radical polymerizable compound and an organoborane initiator, a second radical polymerizable compound, and an organoborane decomplexing agent, at a rate sufficient to form the non-random copolymer. The non-random copolymer may be a silicon gradient polymer. To form the silicon gradient copolymer, the first and second radical polymerizable compounds are polymerized in the presence of the organoborane initiator and the organoborane decomplexing agent. The silicon gradient copolymer has a polymer backbone consisting of organic moieties and has at least one silicon containing pendent group. | 12-01-2011 |
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| 20090270527 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME - Disclosed are cement products, methods of forming cement using the cement product, and methods of using the cement product in orthopedic and dental applications. Generally, the disclosed cement product includes a first component and a second component. The first component comprises a polymerizable resin comprising ethylenic unsaturated double bond, a suitable glycidyl group and/or a suitable isocyanate group. The second component includes a compound comprising more than one type of amine selected from the group consisting of primary amine, secondary amines, tertiary amines and quaternary amines. Alternatively, the second component includes a compound comprising a suitable mercapto (SH—) group, a hindered amine or a dimethylthiotoluenediamine (DMTDA). Optionally, the cement product includes a filler and/or a bioactive component to promote bone formation. | 10-29-2009 |
| 20110004307 | FUSION DEVICE, SYSTEMS AND METHODS THEREOF - The spinal fusion device ( | 01-06-2011 |
| 20110097420 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME - Disclosed are cement products, methods of forming cement using the cement product, and methods of using the cement product in orthopedic and dental applications. Generally, the disclosed cement product includes a first component comprising a polymerizable resin comprising ethylenic unsaturated double bond, a second component comprising a compound comprising more than one type of amine selected from the group consisting of primary amines, secondary amines, tertiary amines and quaternary amines, and, optionally, the cement product includes a bioactive component to promote bone formation. | 04-28-2011 |
| 20110318402 | TRICALCIUM PHOSPHATES, THEIR COMPOSITES, IMPLANTS INCORPORATING THEM, AND METHODS FOR THEIR PRODUCTION - Methods for the synthesis of tricalcium phosphates are presented, as well as a series of specific reaction parameters that can be adjusted to tailor, in specific ways, properties in the tricalcium phosphate precursor precipitate. Particulate tricalcium phosphate compositions having an average crystal size of about 250 nm or less are provided. Compositions of the invention can be used as prosthetic implants and coatings for prosthetic implants. | 12-29-2011 |
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| 20100278156 | DATA COMMUNICATION METHOD USING BODY AREA NETWORK SUPERFRAME - There is provided a data communication method using a body area network superframe including an advertisement period, a contention medium access period, a beacon period, and a data transmit period, the data communication method including: broadcasting, by a coordinator node, predetermined information during the advertisement period; transmitting, by nodes, which wish to transmit data, the data only when carrier is not in use as a result of sensing the carrier after the contention medium access period is initiated and a predetermined backoff time elapses; broadcasting, by each of the nodes, periodic beacon signals during the beacon period; and transmitting, by each of the nodes, continuous data and periodic data during the data transmit period | 11-04-2010 |
| 20100284334 | ASYNCHRONOUS MULTI-CHANNEL ADAPTATION METHOD FOR WIRELESS AD-HOC NETWORK - There is provided an asynchronous multi-channel adaptation method. An asynchronous multi-channel adaptation method according to an aspect of the invention may include: a channel scanning operation in which a new node, participating in a wireless ad-hoc network, scans channels and selects a receiving channel thereof; and a receiving channel information transmission operation in which the new node transmits information on the selected receiving channel thereof to a neighboring node. | 11-11-2010 |
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| 20090300512 | PREFERENCE EDITOR TO FACILITATE PRIVACY CONTROLS OVER USER IDENTITIES - A privacy preference editor enables a user to institute privacy preferences relative to user identity information on a card-based and category-based basis. An identity selector furnishes information cards representative of user identities. The editor allows the user to set a privacy preference for each information card. Any proposed disclosure of an information card invokes its corresponding privacy preference. In turn, an agent engine evaluates the invoked privacy preference against the privacy policy of a relying party seeking the card information. The editor also permits the user to create information categories, populate the categories with a group of relevant user identity attributes, and set a privacy preference to the category. In this way, a category-specific privacy preference can be invoked by using the attribute required by the security policy as an index to the appropriate categorized group where the required attribute resides. | 12-03-2009 |
| 20090300714 | PRIVACY ENGINE AND METHOD OF USE IN A USER-CENTRIC IDENTITY MANAGEMENT SYSTEM - A privacy enforcement engine conducts a process that evaluates user privacy preferences against the privacy policy of a service provider. The engine works in conjunction with an identity selector. The identity selector filters user identity information cards to determine which ones satisfy the requirements of a security policy. The engine identifies privacy preferences that are relevant to the user identity information specified by the successfully filtered cards. The engine evaluates these privacy preferences against the privacy policy, to provide its own filtering operation relative to the exercise of privacy controls. The cards that pass the filtering operation conducted by the engine are deemed available for disclosure. | 12-03-2009 |
| 20090300715 | USER-DIRECTED PRIVACY CONTROL IN A USER-CENTRIC IDENTITY MANAGEMENT SYSTEM - An identity management system incorporates privacy management processes that enable the user to exercise privacy controls over the disclosure of user identity information within the context of an authentication process. A combination includes an identity selector, a privacy engine, and a ruleset. The identity selector directs the release of a user identity in the form of a security token to satisfy the requirements dictated by a security policy. Prior to release of the user identity, the engine conducts a privacy enforcement process that examines the privacy policy of the service provider and determines if it is acceptable. The engine evaluates a ruleset against the privacy policy. A preference editor enables the user to construct, in advance, the ruleset, which embodies the user's privacy preferences regarding the disclosure of identity information. Based on the evaluation results, the user can either approve or disapprove the privacy policy, and so decide whether to proceed with disclosure of the user identity. | 12-03-2009 |
| 20090300716 | USER AGENT TO EXERCISE PRIVACY CONTROL MANAGEMENT IN A USER-CENTRIC IDENTITY MANAGEMENT SYSTEM - A client-side user agent operates in conjunction with an identity selector to institute and exercise privacy control management over user identities managed by the identity selector. The user agent includes the combination of a privacy enforcement engine, a storage of rulesets expressing user privacy preferences, and a preference editor. The editor enables the user to direct the composition of privacy preferences relative to user identities. The preferences can be applied to individual cards and to categorized groups of attributes. The engine evaluates the proper rulesets against the privacy policy of a service provider. The privacy preferences used by the engine are determined on the basis of specifications in a security policy indicating the attribute requirements for claims that purport to satisfy the security policy. | 12-03-2009 |
| 20090300742 | IDENTITY SELECTOR FOR USE WITH A USER-PORTABLE DEVICE AND METHOD OF USE IN A USER-CENTRIC IDENTITY MANAGEMENT SYSTEM - An identity selector manages the identity requirements of an online interaction between a user and a service provider environment. The identity selector is adapted for interoperable use with a user-portable computing device. The user device enables a user to carry identification information and to generate security tokens for use in authenticating the user to a service provider. The identity selector includes an agent module that facilitates communication with the user device. The identity selector imports the user identities from the user device and determines which user identities satisfy a security policy of a relying party. After the user selects one of the eligible user identities, the identity selector generates a token request based on the selected identity and forwards it to the user device, which in response issues a security token. The security token is returned to the identity selector and used to facilitate the authentication process. | 12-03-2009 |
| 20090300746 | SYSTEM INTEGRATING AN IDENTITY SELECTOR AND USER-PORTABLE DEVICE AND METHOD OF USE IN A USER-CENTRIC IDENTITY MANAGEMENT SYSTEM - A combination includes a user-portable computing device, and an identity selector adapted for interoperable use with the user device. The user computing device includes a security token service that issues security tokens in reference to a portfolio of user identities stored as information cards on the user device. The issuance of security tokens employs user attribute information that is stored onboard the user device. The identity selector exports the information cards from the user device and determines which user identity satisfies a security policy promulgated by a relying party as part of an authentication process within the context of an online interaction. The identity selector generates a token request based on one of the eligible user identities, and forwards the token request to the user device to invoke the token issuance operation. The identity selector presents the issued security token to the relying party to comply with the security policy. | 12-03-2009 |
| 20090300747 | USER-PORTABLE DEVICE AND METHOD OF USE IN A USER-CENTRIC IDENTITY MANAGEMENT SYSTEM - A user-portable computing device configured as a smart card enables a user to carry identification information and to generate security tokens for use in authenticating the user to a service provider. The device includes memory for storing user identities as information cards that are exported to a host computer, presented to a user in visual form, and then selected for use in the authentication process. A security token service installed on the device issues a security token in response to a token request sent from the host computer that references the selected user identity. The security token service uses user attribute information stored on the user device to compose the claim assertions needed to issue the security token. The token is returned to the host computer and used to facilitate the authentication process. | 12-03-2009 |
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| 20090319459 | Physically-animated Visual Display - A physically animated visual display is a robotic device, capable of multiple degree-of-freedom motion, that is adapted to improve a user's emotional state, cognitive performance, and comfort level through reactive and goal-directed manipulation of the position of the display. The affective-cognitive system comprises a feature extraction subsystem for deriving physical information about a user from data obtained from sensors, a perception subsystem for processing the data in order to determine the user's current emotional state, affective-cognitive state, or posture, an action selection subsystem for determining an action to be taken in response, and a motor system for physically animating the robotic device in accordance with the determined action. The system may include feedback modeling based on a reaction of the user to the movement of the apparatus increasing or decreasing the probability of choosing the current behavior based on the user's reaction. | 12-24-2009 |
| 20110077996 | Multimodal Affective-Cognitive Product Evaluation - Repeated random-outcome trials together with affective, cognitive, and behavioral measures of liking and wanting may be used to assess consumer preferences. In an exemplary implementation of this invention, in each trial, a participant selects one of two sources (e.g., one of two beverage dispensers) of a product (e.g., a beverage). Each source dispenses the product randomly, with a probability initially unknown to the participant, but which he or she may guess while trying to select the most desired product. Affective measures of a participant's facial valence and sympathetic nervous system activation are taken while deciding on, anticipating the arrival of, receiving, using, evaluating, and reflecting on the product. The affective measures are combined with cognitive self-report questionnaire items and with behavioral measures to infer wanting and liking of a product. | 03-31-2011 |
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| 20090073078 | Systems, Methods and Apparatuses for High Power Complementary Metal Oxide Semiconductor (CMOS) Antenna Switches Using Body Switching and External Component in Multi-Stacking Structure - Embodiments of the invention may provide for a CMOS antenna switch, which may be referred to as a CMOS SPDT switch. The CMOS antenna switch may operate at a plurality of frequencies, perhaps around 900 MHz, 1.9 GHz and 2.1 GHz according to an embodiment of the invention. The CMOS antenna switch may include both a receiver switch and a transmit switch. The receiver switch may utilize a multi-stack transistor with body substrate switching and attachment of external capacitor between drain and gate to block high power signals from the transmit path as well as to maintain low insertion loss at the receiver path. Exemplary embodiments of the CMOS antenna switch may provide for 38 dBm P 0.1 dB at multi bands (e.g., 900 MHz, 1.8 GHz, and 2.1 GHz). In addition, −60 dBc second and third harmonic performance up to 30 dBm input, may be obtained according to example embodiments of the invention. | 03-19-2009 |
| 20110068636 | SYSTEMS AND METHODS FOR A SPDT SWITCH OR SPMT SWITCH WITH TRANSFORMER - A SPDT or SPMT switch may include a transformer having a primary winding and a secondary winding, where a first end of the secondary winding is connected to a single pole port, where a first end of the primary winding is connected to a first throw port; a first switch having a first end and a second end, where the first end is connected to ground; and a second switch, where a second end of the secondary winding is connected to both a second end of the first switch and a first end of the second switch, where a second end of the second switch is connected to a second throw port, where the first switch controls a first communication path between the single pole port and the first throw port, and where the second switch controls a second communication path between the second throw port and the single pole port. | 03-24-2011 |
| 20110127849 | HIGH-POWER TUNABLE CAPACITOR - A tunable capacitor device may be provided in accordance with example embodiments of the invention. The tunable capacitor device may include a first capacitor; a second capacitor; a third capacitor, where the first, second, and third capacitors are connected in series, wherein the second capacitor is positioned between the first capacitor and the second capacitor; and at least one switch transistor, where the at least one switch transistor is connected in parallel with the second capacitor. | 06-02-2011 |
| 20110273355 | SYSTEMS AND METHODS FOR COMPLEMENTARY METAL-OXIDE-SEMICONDUCTOR (CMOS) DIFFERENTIAL ANTENNA SWITCHES USING MULTI-SECTION IMPEDANCE TRANSFORMATIONS - Example embodiments of the invention are directed to CMOS differential antenna switches with multi-section impedance transformation. The differential architecture can provide relief from large voltage swings of the power amplifiers by distributing the voltage stress over the receiver switch with two of the identical or substantially similar single-ended switches. In order to reduce the voltage stress further, multi-section impedance transformations can be used. Degraded insertion loss due to the impedance transformation technique can be compensated by selecting an optimal impedance for the antenna switch operation. Accordingly, the use of the multi-section impedance transformations with the differential antenna switch architecture enables high power handling capability for the antenna switch with acceptable efficiency for the transmitter module. | 11-10-2011 |
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| 20110257196 | COMPOUNDS FOR TREATMENT OF CANCER - The present invention relates to novel compounds having anti-cancer activity, methods of making these compounds, and their use for treating cancer and drug-resistant tumors, e.g. melanoma, metastatic melanoma, drug resistant melanoma, prostate cancer and drug resistant prostate cancer. | 10-20-2011 |
| 20120022121 | INDOLES, DERIVATIVES AND ANALOGS THEREOF AND USES THEREFOR - Indole derivatives and analogous compounds and pharmaceutical compositions comprising the same are provided. Also provided are methods of using these compounds to inhibit tubulin polymerization in a cell associated with a proliferative disease or to treat cancer, metastatic cancer, resistant cancer or multidrug resistant cancer, including inter-alia: prostate cancer, breast cancer, melanoma, colon cancer and bladder cancer. | 01-26-2012 |
| 20120071524 | COMPOUNDS FOR TREATMENT OF CANCER - The present invention relates to novel compounds having anti-cancer activity, methods of making these compounds, and their use for treating cancer and drug-resistant tumors, e.g. melanoma, metastatic melanoma, drug resistant melanoma, prostate cancer and drug resistant prostate cancer. | 03-22-2012 |
