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Agnieszka

Agnieszka Ambrozak, Buchs CH

Patent application numberDescriptionPublished
20090186913Tetrahalogenated compounds useful as inhibitors of angiogenesis - Methods for inhibiting a neoplasm in a subject and methods of inhibiting undesired angiogenesis that include administering to a subject a therapeutically effective amount of at least one novel tetrahalogenated compound, or a pharmaceutically acceptable salt thereof.07-23-2009

Agnieszka Burzynska, Zawiercie PL

Patent application numberDescriptionPublished
20080214876Process for Preparation of Pharmaceutically Pure Anhydrous Calcipotriol - A process for the preparation of a pharmaceutical-grade anhydrous calcipotriol comprising: (a) dissolving crude calcipotriol having a water content of X % by weight in a first solvent or in a mixture of two or more first solvents, said first solvent or said mixture of two or more first solvents forming an azeotropic system with water, to obtain a solution of crude calcipotriol; (b) obtaining an intermediate calcipotriol by (i) placing said solution of crude calcipotriol under a reduced pressure and evaporating, if X is greater than or equal to 1, or (ii) crystallizing, if X is lower than 1; and (c) re-dissolving said intermediate calcipotriol in a second solvent or a mixture of two or more second solvents, said second solvent being anhydrous, and crystallizing at least once to obtain pharmaceutical-grade anhydrous calcipotriol.09-04-2008

Agnieszka Ciesielska, Warszawa PL

Patent application numberDescriptionPublished
20090105483PROCESS FOR THE PREPARATION OF PRAMIPEXOLE BASE AND/OR ITS SALTS - The process for the preparation of pramipexole base and/or its pharmaceutically acceptable salts, especially the hydrochloride salt, in the alkylation reaction of (S)-(−)2,6-diamino-4,5,6,7-tetrahydrobenzothiazole with an alkylating agent, wherein the reaction is carried out in the absence of a base, and in a solvent from which the resulting N-monoalkylated product selectively precipitates out as a salt. After isolation from the reaction mixture, the N-monoalkylated product is converted a) into the free pramipexole base upon treatment with an inorganic base and is then converted into another pharmaceutically acceptable pramipexole salt; or b) directly into another pharmaceutically acceptable pramipexole salt or the hydrate thereof.04-23-2009

Agnieszka Czechowicz, Menlo Park, CA US

Patent application numberDescriptionPublished
20100226927SELECTIVE IMMUNODEPLETION OF ENDOGENOUS STEM CELL NICHE FOR ENGRAFTMENT - The present invention provides a clinically applicable method of stem cell transplantation that facilitates engraftment and reconstitutes immunocompetence of the recipient without requiring radiotherapy or chemotherapy, and without development of GVHD or graft rejection. Aspects of the present invention are based on the discovery that the depletion of the endogenous stem cell niche facilitates efficient engraftment of stem cells into that niche. In particular, the present invention combines the use of selective ablation of endogenous stem cells, in combination with the administration to the recipient of exogenous stem cells, resulting in efficient, long-term engraftment and tolerance.09-09-2010

Agnieszka Dryla, Vienna AT

Patent application numberDescriptionPublished
20110020402Method For Identification, Isolation And Production Of Antigens To A Specific Pathogen - Described is a method for identification, isolation and production of hyperimmune serum-reactive antigens from a specific pathogen, a tumor, an allergen or a tissue or host prone to autoimmunity, said antigens being suited for use in a vaccine for a given type of animal or for humans, which is characterized by the following steps:—providing an antibody preparation from a plasma pool of said given type of animal or from a human plasma pool or individual sera with antibodies against said specific pathogren, tumor, allergen or tissue or host prone to auto-immunity,—providing at least one expression library of said specific pathogen, tumor, allergen or tissue or host prone to auto-immunity,—screening said at least one expression library with said antibody preparation, identifying antigens which bind in said screening to antibodies in said antibody preparation, —screening the identified antigens with individual antibody preparations from individual sera from individuals with antibodies against said specific pathogen, tumor, allergen or tissue or host prone to auto-immunity,—identifying the hyperimmune serum-reactive antigen portion of said identified antigens and which hyperimmune serum-reactive antigens bind to a relevant portion of said individual antibody preparations from said individual sera and—optionally isolating said hyperimmune serum-reactive antigens and producing said hyperimmune serum-reactive antigens by chemical or recombinant methods.01-27-2011

Patent applications by Agnieszka Dryla, Vienna AT

Agnieszka Glebocka, Madison, WI US

Patent application numberDescriptionPublished
200901708222-Methylene-20-Methyl-19,24,25,26,27-Pentanor-Vitamin D Analogs - This invention discloses 2-methylene-20-methyl-19,24,25,26,27-pentanor-vitamin D analogs, and specifically 2-methylene-20-methyl-1α-hydroxy-19,24,25,26,27-pentanor-vitamin D07-02-2009
2010000994419-Nor-Vitamin D Analogs with 1,2-Dihydrofuran Ring - 19-nor-vitamin D analogs having an additional dihydrofuran ring connecting the 1α-oxygen and carbon-2 of the A-ring of the analog, and pharmaceutical uses therefore, are described. These compounds exhibit selective in vitro and in vivo activities, making them therapeutic agents for the treatment or prophylaxis of autoimmune diseases, some types of cancers, secondary hyperparathyroidism, psoriasis, or other skin diseases.01-14-2010
2010000994519-NOR-VITAMIN D ANALOGS WITH 3,2-DIHYDROFURAN RING - 19-nor-vitamin D analogs having an additional dihydrofuran ring connecting the 3β-oxygen and carbon-2 of the A-ring of the analog, and pharmaceutical uses therefore, are described. These compounds exhibit selective in vitro and in vivo activities, making them therapeutic agents for the treatment or prophylaxis of autoimmune diseases, some types of cancers, metabolic bone diseases, osteomalacia, osteopenia, secondary hyperparathyroidism, psoriasis, or other skin diseases.01-14-2010
2011008212219-Nor-Vitamin D Analogs With 1,2- or 3,2-Cyclopentene Ring - 19-nor-vitamin D analogs having an additional cyclopentene ring connecting carbon 1 and carbon 2, or connecting carbon 3 and carbon-2 of the A-ring of the analog, and pharmaceutical uses therefore, are described. These compounds exhibit selective in vitro activities, making them therapeutic agents for the treatment or prophylaxis of some types of cancers, particularly leukemia, colon cancer, breast cancer, skin cancer or prostate cancer.04-07-2011

Patent applications by Agnieszka Glebocka, Madison, WI US

Agnieszka Glebocka, Warsaw PL

Patent application numberDescriptionPublished
200902813401ALPHA-HYDROXY-2-(3'-HYDROXYPROPYLIDENE)-19-NOR-VITAMIN D COMPOUNDS AND METHODS OF MAKING AND TREATMENT THEREOF - Disclosed are 1α-hydroxy-2-(3′-hydroxypropylidene)-19-nor-vitamin D compounds, pharmaceutical compositions, and methods of making and treatment thereof. The compounds are generally directed to biologically active 2-alkylidene-19-nor-vitamin D compounds and analogs thereof characterized by the presence of a 3′-hydroxypropylidene moiety at C-2 and the presence of an abbreviated alkyl side-chain free of any hydroxyl moiety.11-12-2009

Patent applications by Agnieszka Glebocka, Warsaw PL

Agnieszka Hanulak, Birmingham, MI US

Patent application numberDescriptionPublished
20110070566Meal Planning System - A meal planning system may include first, second and third grocery lists, a plurality of first recipes and a plurality of second recipes. The second grocery list may be associated with the first grocery list. The first recipes may be associated with the second grocery list. Each of the first recipes may include food items from at least one of the first and second grocery lists. The second grocery list includes enough food items to prepare the first recipes. The third grocery list may be associated with the first grocery list. The second recipes may be associated with the third grocery list. Each of the second recipes may include food items from at least one of the first and third grocery lists. The third grocery list includes enough food items to prepare the second recipes. The grocery lists and recipes may be displayed on cards and/or an electronic device.03-24-2011

Agnieszka Kierzkowska, Polkowice PL

Patent application numberDescriptionPublished
20110087286UNLOADING D-DYNAMIC INTERVERTEBRAL DEVICE - An unloading dynamic intervertebral device comprising a first bar and a second bar configured for providing an even, steady and adjustable decompression of the intervertebral interspinous space and for maintaining the distance between at least two vertebrae. The first bar may comprise a guideline with an elongated gap formed therein. The second bar may comprise a guide having at least one tang interposed within the elongated gap of the first bar, such that the first bar and the second bar are rotationally and slidably connected with each other about the tang. An end of the first bar and an opposing end of the second bar may comprise shaped bearings configured for bony elements of the spine. The first and second bar may be movable relative to each other between an open position and a closed position.04-14-2011

Agnieszka Korzeniowska-Kowal, Miekinia PL

Patent application numberDescriptionPublished
20110008873PURIFIED BACTERIOPHAGE, ITS PREPARATION AND APPLICATION - A method of preparation of purified bacteriophage with increased antibacterial activity, in which from bacterial lysate of phages is obtained, advantageously in the presence of lysozyme, chelating factor and detergent, in a continuous manner with ultrafiltration on membranes, the phage containing high molecular mass preparation, devoid of bacterial cell wall and other contaminants, free of toxins and endotoxins, active in tests of bacterial lysis, which is characterized by chromatography HPLC, In SDS-PAGE electrophoresis, immunoblotting, biological tests of bacterial lysis, and is dedicated for phage therapy of bacterial infections and tumors and for production of phage deriving pharmaceutical preparations.01-13-2011

Agnieszka Kurabe, Tokyo JP

Patent application numberDescriptionPublished
20110181740IMAGE BLUR CORRECTION DEVICE, IMAGING LENS UNIT, AND CAMERA UNIT - An image blur correction device according to the present invention includes an a base (07-28-2011

Agnieszka Lach, Chicago, IL US

Patent application numberDescriptionPublished
20110136256METHODS AND KITS FOR DECREASING INTERFERENCES IN PLASMA OR SERUM CONTAINING ASSAY SAMPLES OF SPECIFIC BINDING ASSAYS - Methods and kits are provided for decreasing interferences and inaccuracies due to nonoptimal sample handling of blood samples in plasma or serum containing assay samples of specific binding assays by addition of a large polycation to the assay sample during the specific binding assay.06-09-2011

Agnieszka Marcinowicz-Flick, Ames, IA US

Patent application numberDescriptionPublished
20110053941IDO Inhibitors - Presently provided are methods for (a) modulating an activity of indoleamine 2,3-dioxygenase comprising contacting an indoleamine 2,3-dioxygenase with a modulation effective amount of a compound as described in one of the aspects described herein; (b) treating indoleamine 2,3-dioxygenase (IDO) mediated immunosuppression in a subject in need thereof, comprising administering an effective indoleamine 2,3-dioxygenase inhibiting amount of a compound as described in one of the aspects described herein; (c) treating a medical conditions that benefit from the inhibition of enzymatic activity of indoleamine-2,3-dioxygenase comprising administering an effective indoleamine 2,3-dioxygenase inhibiting amount of a compound as described in one of the aspects described herein; (d) enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent and a compound as described in one of the aspects described herein; (e) treating tumor-specific immunosuppression associated with cancer comprising administering an effective indoleamine 2,3-dioxygenase inhibiting amount of a compound as described in one of the aspects described herein; and (f) treating immunosuppression associated with an infectious disease, e.g., HIV-I infection, comprising administering an effective indoleamine 2,3-dioxygenase inhibiting amount a compound as described in one of the aspects described herein.03-03-2011

Agnieszka Opalinska, Zyrardow PL

Patent application numberDescriptionPublished
20090256083Zirconium Dioxide Luminescence Oxygen Sensor - A method of measuring oxygen partial pressure in gases, such as hot engine exhaust gases, uses a calibrated luminescence sensor and comprises the steps of bringing nanocrystalline zirconinum dioxide ZrO10-15-2009

Agnieszka Seyda, Belle Mead, NJ US

Patent application numberDescriptionPublished
20110282324Multi-Chamber Therapeutic Cell Applicator Instrument - A surgical device comprises a housing, a plurality of media reservoirs, an end effector, and a pumping device. Each media reservoir is configured to receive at least one component of a tissue repair composition. The end effector is configured for insertion into a lumen to deliver a tissue repair composition into that lumen. The end effector has at least one fluid conduit and at least one orifice in communication with the fluid conduit. The pumping device is operable to urge a tissue repair composition comprising at least a portion of the contents of the plurality of media reservoirs through the fluid conduit of the end effector such that the tissue repair composition is expelled from the at least one orifice. The media reservoirs may contain medical fluid components such as viable cells and scaffold material to repair a fistula or address some other condition in a patient.11-17-2011

Agnieszka Sierzchala, Boulder, CO US

Patent application numberDescriptionPublished
200802279642'-silyl containing thiocarbonate protecting groups for RNA synthesis - Nucleoside monomers, nucleic acids, e.g., oligonucleotides and polynucleotides, methods of making each, methods of deprotecting each, and the like are disclosed herein. Aspects of the invention include 2′ silyl containing thiocarbonate protecting groups. Corresponding compositions and methods are provided.09-18-2008
20090209479THIOCARBON-PROTECTING GROUPS FOR RNA SYNTHESIS - Aspects of the invention include 2′ protected nucleoside monomers that are protected at the 2′ site with thiocarbon protecting groups. Thiocarbon protecting groups of interest include thiocarbonate, thionocarbonate, dithiocarbonate groups, as well as thionocarbamate protecting groups. Aspects of the invention further include nucleic acids that include the protecting groups of the invention, as well as methods of synthesizing nucleic acids using the protecting groups of the invention.08-20-2009
20100076183PROTECTED MONOMER AND METHOD OF FINAL DEPROTECTION FOR RNA SYNTHESIS - A nucleoside monomer that is protected by a thionocarbamate protecting group is provided, as well as a method for making a polynucleotide that uses the same. Also provided is a polynucleotide synthesis method that employs a diamine to deprotect a protected polynucleotide.03-25-2010

Patent applications by Agnieszka Sierzchala, Boulder, CO US

Agnieszka Sosna, London GB

Patent application numberDescriptionPublished
20110054846Monitoring the Performance of a Computer - A computer implemented method of monitoring the performance of a computer comprises monitoring the computer to determine the values of a plurality of activity metrics of the monitored computer. A weighted combination of functions of the determined values is calculated as a measure of performance of the monitored computer. The weighted combination may be a weighted combination of net values of activity metrics. In one embodiment, the net values are calculated as the said values of the plurality of activity metrics of the monitored computer excluding contributions to the values from the one or more predetermined activities. In another embodiment, the net values are calculated as follows. The total values of the respective activity metrics of the monitored computer are determined. The contribution(s) to the said total values of the said one or more predetermined activities are determined The said contribution(s) are subtracted from the said total values to provide net values. The weighted combination may be used to control power consumption or otherwise take action in relation to the computer.03-03-2011

Agnieszka Swiateck-Urban, Pittsburgh, PA US

Patent application numberDescriptionPublished
20100197593Modulators of the ABC Transporter Family and Methods for their Use - An isolated factor derived from the bacterium 08-05-2010

Agnieszka Szufarska, Gdansk PL

Patent application numberDescriptionPublished
20110195719Configuration of Nodes for Local Data Transmission Which are Under an Overlay Wide Area Macro Network Operated on the Same Frequency Layer - At a node for local data transmission which is under an overlay wide area macro network operated on the same frequency layer, conditions of a wide area cell of the overlay wide area macro network are obtained, wherein the wide area cell is measured as a cell with a certain received signal level at a location of the node. Based on the conditions of the wide area cell, an allocation of channels for local area data transmission from the node is set such that interference of the channels for the local area data transmission with allocated wide area channels of the wide area cell is avoided or minimized.08-11-2011
20110242965Automatic connection re-establishment using escape carrier - In one exemplary aspect of this invention a method includes receiving at a user equipment from a wide area network access node information identifying at least one predetermined radio frequency carrier; initiating, in response to a presence of an interferer on a radio frequency carrier that is being used for a current connection between the user equipment and the network access node, a connection re-establishment procedure, where the interferer has the potential to cause a radio link failure of the current connection on the radio frequency carrier; and transmitting a connection re-establishment request to the network access node on the predetermined radio frequency carrier. The interferer can be a closed subscriber group network access node that the user equipment is not authorized to gain access to.10-06-2011
20110250881Apparatus, Method, System and Program for Power Control or Power Setting - Embodiments provide an apparatus, method, product and storage medium for controlling or setting a transmit power of a femto cell depending on a received power of at least one neighbouring macro cell.10-13-2011

Agnieszka Wojtalewicz-Kasprzak, Emlichheim DE

Patent application numberDescriptionPublished
20090162267Method for Recovery of Rare Earths from Fluorescent Lamps - Method for recovery of rare earths from fluorescent lamps. The method comprises six steps. The individual process steps are: Mechanical separation of coarse components. Separation of the halophosphate. Extraction in acids of easily soluble rare-earth fluorescent substances (mainly Y, Eu-oxide) Extraction in acids of rare-earth fluorescent substances which dissolve with difficulty (for example rare-earth phosphates) Breakdown of the remaining components which contain rare earths (for example rare-earth-aluminates) Final treatment.06-25-2009

Agnieszka Wojtkielewicz, Bialystok PL

Patent application numberDescriptionPublished
20110311652Novel Saponin Compounds, Methods of Preparation Thereof, Use Thereof and Pharmaceutical Compositions - This invention relates to novel saponin compounds of formula II wherein MBz denotes p-methoxybenzoyl, and R is selected from the group comprising C12-22-2011