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Adrian L.

Adrian L. Schwan, Guelph CA

Patent application numberDescriptionPublished
20100055164SYNTHETIC LUNG SURFACTANT AND USE THEREOF - The present invention relates to synthetic lung surfactant compositions that contain one or more of phospholipase-resistant phospho-glycerol derivatives, phospholipase-resistant phospho-choline derivatives, and surface active proteins or peptides, more preferably a combination of at least two or all three of these materials. Novel phospholipase-resistant phospho-glycerol derivatives, phospholipase-resistant phospho-choline derivatives, and surface active peptides are also disclosed herein. Uses of the surfactant compositions of the present invention to treat endogenous surfactant dysfunctional or deficient lung tissue, to prepare synthetic peptides for use in the surfactant compositions, and to deliver therapeutic agents are also disclosed.03-04-2010

Adrian L. Smith, Simi Valley, CA US

Patent application numberDescriptionPublished
20090054405PI3 kinase modulators and methods of use - The present invention comprises a new class of compounds capable of modulating the activity of PI3 kinase and, accordingly, useful for treatment of PI3 kinase mediated diseases, including melanomas, carcinomas and other cancer-related conditions. The compounds have a general Formula I02-26-2009
20100273764INHIBITORS OF PI3 KINASE AND/OR MTOR - The present invention relates to compounds of Formula I, or a pharmaceutically acceptable salt thereof;10-28-2010
20100324047RAF KINASE MODULATORS AND METHODS OF USE - The present invention comprises a new class of compounds capable of modulating the activity of Raf kinase and, accordingly, useful for treatment of Raf kinase mediated diseases, including melanomas, tumors and other cancer-related conditions. The compounds have a general Formula (I) wherein each of A12-23-2010

Patent applications by Adrian L. Smith, Simi Valley, CA US

Adrian L. Walker, Little Paxton GB

Patent application numberDescriptionPublished
20110059551Assay Device - Disclosed is an assay device to determine the presence of at least one analyte of interest in a liquid sample, the device comprising means for generating a first signal (the ‘test’ signal) which indicates the presence and/or amount of analyte of interest in the sample; and means for generating a second signal, the generation of which second signal indicates both (a) the test has been successfully conducted, and that (b) sufficient time has elapsed following contact of the assay device with the liquid sample for the test to be read and the first signal to have been properly generated.03-10-2011