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Addepalli

Haripriya Addepalli, Cambridge, MA US

Patent application numberDescriptionPublished
20110223665ENHANCEMENT OF siRNA SILENCING ACTIVITY USING UNIVERSAL BASES OR MISMATCHES IN THE SENSE STRAND - One aspect of the present invention relates to a double stranded nucleic acid useful as an siRNA, that has a sense strand and an antisense strand relative to a target nucleic acid, where the sense strand contains one or more modified nucleobases, or one or more mismatch base pairings with the antisense strand. Another aspect of the present invention relates to a single-stranded oligonucleotide comprising at least one nucleoside comprising a non-natural nucleobase. Another aspect of the invention relates to a method of gene silencing, comprising administering to a mammal in need thereof a therapeutically effective amount of a double-stranded oligonucleotides containing a sense strand and an antisense strand, where the sense strand contains one or more modified nucleobases, or one or more mismatch base pairings with the antisense strand.09-15-2011

Murali Addepalli, Maharashtra IN

Patent application numberDescriptionPublished
20090054366RNAi MEDIATED KNOCKDOWN OF NUMA FOR CANCER THERAPY - This invention relates to the use of short interfering nucleic acid molecules (siRNA) to inhibit Nuclear Mitotic Apparatus Protein (NuMA) gene expression and their use in treatment of disease, including cancer.02-26-2009
20100286244RNAi MEDIATED KNOCKDOWN OF NUMA FOR CANCER THERAPY - This invention relates to the use of short interfering nucleic acid molecules (siRNA) to inhibit Nuclear Mitotic Apparatus Protein (NuMA) gene expression and their use in treatment of disease, including cancer.11-11-2010

Murali Krishna Addepalli, Navi Mumbai IN

Patent application numberDescriptionPublished
20100285107SHORT NUCLEIC ACID MOLECULE-MEDIATED MODULATION OF AURORA B KINASE EXPRESSION AND COMBINATIONS FOR USE IN ANTICANCER THERAPY - This invention relates to the use of short nucleic acid molecules that modulate Aurora-B kinase (AurkB) expression. The invention includes compounds, compositions and methods useful for the modulation of expression and activity of genes involved in the AurkB pathway. In one embodiment, the present invention provides short nucleic acid molecules, such as siRNA, which can be used in treating, preventing, or inhibiting cancer, and any other proliferative disease, trait or condition, which respond to a reduction in AurkB expression in a cell or tissue. Such short nucleic acid molecules can be used alone or in combination with other treatments or therapies, including short nucleic acid molecules that modulate expression of EGFR.11-11-2010

Pratima Addepalli, Monroe, MI US

Patent application numberDescriptionPublished
20100257871Thin film thermoelectric devices for power conversion and cooling - A thermoelectric device having at least one thermoelectric unit including at least one thermoelectric pair of n-type and p-type thermoelements, a first header coupled to one side of the thermoelectric pair, and a second header coupled to a second side of the thermoelectric pair. The thermoelectric pair has a thermal conduction channel area smaller than an area of the first header or the second header such that the thermal conduction area is a fraction of the area of the first header or the second header.10-14-2010
20110132450Back Contact Deposition Using Water-Doped Gas Mixtures - A method of manufacturing a photovoltaic module may include depositing a semiconductor material adjacent to a substrate; and depositing a back contact material adjacent to the semiconductor material, where depositing the back contact material may include directing a feed gas including hydrogen toward the substrate.06-09-2011

Patent applications by Pratima Addepalli, Monroe, MI US

Pratima Addepalli, Cary, NC US

Patent application numberDescriptionPublished
20090282852Thin Film Thermoelectric Devices for Hot-Spot Thermal Management in Microprocessors and Other Electronics - A structure, system and method for controlling a temperature of a heat generating device in a solid medium, wherein heat is extracted from the medium into at least one heat extraction device, the heat extraction device dissipates heat into an environment apart from the medium by a heat sink thermally coupled to the heat extraction device; and heat from the medium is dissipated into the heat sink by a first thermal interface material thermally coupling the heat sink to the medium.11-19-2009

Pratima V. Addepalli, Monroe, MI US

Patent application numberDescriptionPublished
20110061736PHOTOVOLTAIC BACK CONTACT - A method to preparing Cadmium telluride surface before forming metal back contact is disclosed. The method can include removing carbon from Cadmium telluride surface.03-17-2011
20110146784Photovoltaic device back contact - A method for manufacturing a photovoltaic device may include depositing a semiconductor absorber layer on a substrate, depositing a molybdenum in the presence of a nitrogen to form a molybdenum nitride in contact with the semiconductor absorber layer, and doping the molybdenum nitride with a copper dopant.06-23-2011
20120024338Back Contact Formation - A photovoltaic cell may include a carbon residue and a copper ion on a cadmium telluride layer.02-02-2012
20120042929ELECTRICAL CONTACT - A photovoltaic device with a low-resistance stable electrical back contact is disclosed. The photovoltaic device can have a CuTe02-23-2012

Swarnagowri Addepalli, Bangalore IN

Patent application numberDescriptionPublished
20120068592RARE EARTH DOPED LUMINESCENT MATERIAL - A luminescent material includes an aluminate phosphor of formula I A03-22-2012