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Abrignani

Sergio Abrignani, Serre Di Rapolano (siena) IT

Patent application numberDescriptionPublished
20100166777HEMATOPOIETIC CELLS THAT EXPRESS MOSC-1 - The present invention relates to ex-vivo cells belonging to the hematopoietic system, characterized by the presence of MOSC-1 protein on cell surface, methods for isolating them and uses thereof.07-01-2010
20100183562SUB -POPULATION OF HEMATOPOIETIC STEM CELLS THAT EXPRESS THE CRISP-1 PROTEIN - The subject of the present invention is a sub-population of isolated hematopoietic stem cells that express the CRISP-1 gene and produce the CRISP-1 protein on the cytoplasmic membrane of the cell, their isolation and their application in the therapeutic/diagnostic/prognostic field.07-22-2010
20110038875HEMATOPOIETIC CELLS EXPRESSING THE PROTEIN SUSD3 AND LIGANDS FOR THE PROTEIN SUSD3 - The present invention relates to ex vivo hematopoietic cells characterized by the expression of the protein SUSD3 on the surface of said cells, to methods for preparing said cells and to ligands for SUSD3.02-17-2011

Sergio Abrignani, Serre Di Rapolano IT

Patent application numberDescriptionPublished
20110002938HEMATOPOIETIC CELLS EXPRESSING THE PROTEIN KRTCAP3 AND LIGANDS FOR THE PROTEIN KRTCAP3 - The present invention relates to ex vivo hematopoietic cells characterized by the expression of the protein KRTCAP3 on the surface of said cells, to methods for isolating said cells and to ligands for KRTCAP3.01-06-2011

Sergio Abrignani, Vagliagli (si) IT

Patent application numberDescriptionPublished
20090025098Hepatitis C receptor protein CD81 - The present invention relates to the use of CD81 protein and polynucleic acid in the therapy and diagnosis of hepatitis C and pharmaceutical compositions, animal models and diagnostic kits for such purposes.01-22-2009
20100203501Assay to detect HCV receptor binding - Identification of HCV receptor target cells using HCV receptor-binding ligands and cell separation by flow cytofluorimetry is described. HCV receptor target cells are employed to conduct assays for HCV receptor-binding ligands in order to identify potential HCV vaccine candidates. HCV receptor target cells are used to measure antibody neutralisation to monitor vaccine development, as a diagnostic of HCV infection and to develop neutralising antibodies for passive immunisation.08-12-2010

Patent applications by Sergio Abrignani, Vagliagli (si) IT

Sergio Abrignani, Vagliagli IT

Patent application numberDescriptionPublished
20100143293T cell activation - A method for antigen independent activation of T cells comprising contacting T cells with a combination of cytokines such as two or more of interleukin-2, interleukin-6 and tumor necrosis factor α.06-10-2010
20110159039ELICITING HCV-SPECIFIC ANTIBODIES - Described herein is a method of eliciting antibodies and neutralizing of binding antibodies against a hepatitis C virus (HCV) E1E2 or E2 antigen using HCV E2 or HCV E1E2 polypeptides and/or HCV E2 or E1E2 polynucleotides. Elicitation of anti-E2 antibodies and anti-E2 NOB antibodies can be used, inter alia, to provide model systems to optimize anti-E2 antibody responses and/or anti-E2 NOB antibody responses to HCV and to provide prophylactic or therapeutic treatment against HCV infection.06-30-2011

Patent applications by Sergio Abrignani, Vagliagli IT