| Patent application number | Description | Published |
|---|
| 20080213781 | Methods of detecting methylation patterns within a CpG island - A method of increasing sensitivity of a DNA methylation assay by determining complementation within a CpG island of the methylated DNA. | 09-04-2008 |
| 20080254455 | DETECTING PROSTATE CANCER - Methods and kits for detecting prostate cancer in urine samples include detecting the methylation status of various genes. | 10-16-2008 |
| 20080305473 | Propagation of primary cells - The present invention provides a method of propagating cells of interest obtained from a biological specimen by enriching the cells under conditions that maintain sufficient cell viability; and propagating the cells under conditions effective to allow cell viability, proliferation and integrity. | 12-11-2008 |
| 20090042290 | METHOD OF MODIFYING A MACROMOLECULE WITHOUT PRIOR EXTRACTION FROM A SAMPLE - The present invention encompasses a method of modifying a macromolecule without prior extraction from a sample by converting the macromolecule in the sample with a chemical, removing or converting chemical intermediates, if necessary; and purifying the resulting modified macromolecule. | 02-12-2009 |
| 20090047656 | Molecular analysis of primary cells - The present invention provides a method of propagating cells of interest obtained from a biological specimen by a) enriching the cells under conditions that maintain sufficient cell viability; and b) propagating the cells under conditions effective to allow cell viability, proliferation and integrity. | 02-19-2009 |
| 20090186359 | DETECTING PROSTATE CANCER - An assay for detecting prostate cancer includes reagents for detecting the methylation of GSTP1 and HIC-1 genes. | 07-23-2009 |
| 20090186360 | Detection of GSTP1 hypermethylation in prostate cancer - An assay for detecting prostate cancer includes reagents for detecting multiple methylation markers from within one gene such as GSTP1. | 07-23-2009 |
| 20100003670 | CHARACTERIZING PROSTATE CANCER - Methods and kits for predicting the course or aggressiveness of prostate cancer include detecting the methylation status of various genes. | 01-07-2010 |
| 20100021886 | Methods and Materials for Identifying the Origin of a Carcinoma of Unknown Primary Origin - The present invention provides a method of identifying origin of a metastasis of unknown origin by obtaining a sample containing metastatic cells; measuring Biomarkers associated with at least two different carcinomas; combining the data from the Biomarkers into a linear discrimination analysis where the linear discrimination analysis normalizes the Biomarkers against a reference; and imposes a cut-off which optimizes sensitivity and specificity of each Biomarker, weights the prevalence of the carcinomas and selects a tissue of origin determining origin based on highest probability determined by the linear discrimination analysis or determining that the carcinoma is not derived from a particular set of carcinomas; and optionally measuring Biomarkers specific for one or more additional different carcinoma, and repeating the steps for additional Biomarkers. | 01-28-2010 |
| 20100081145 | Detecting Prostate Cancer - Methods and kits for detecting prostate cancer in urine samples include detecting the methylation status of various genes. | 04-01-2010 |
