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Abdellah
Abdellah Ajji, Mount Royal CA
| Patent application number | Description | Published |
|---|---|---|
| 20100305687 | NON-WOVEN MAT AND METHO OF PRODUCING SAME - A mat having a highly uniform porosity distribution is produced by consolidating 15 or more layers of melt blown webs (or the like) having different orientations. Control over the porosity is provided by using webs that exhibit a narrow, unimodal distribution of fiber diameters over the bulk of its distribution, such as in the top 80%. A compliance of the mats can be chosen by selecting a number and orientation of the webs. It is thus possible to produce mats that are good candidates for vascular grafts, for example. The uniformity of the porosity within the range of 6 μm to 30 μm permits seeding of the vascular graft with endothelial and smooth muscle cells. The mats have the demonstrated ability to retain, and support growth of, smooth muscle cells and endothelial cells. | 12-02-2010 |
Abdellah Benabdelmouna, Rochefort FR
| Patent application number | Description | Published |
|---|---|---|
| 20100107987 | PRODUCTION OF BIVALVE TETRAPLOID MOLLUSKS FROM DIPLOID PARENTS - The invention relates to a method for producing viable tetraploid bivalve mollusks, by fertilisation of diploid female ovocytes with diploid male sperm, followed by the induction of the retention of the first polar body of the fertilised eggs, isolation from the obtained larvae of a larval sub-population enriched in tetraploids and selective raising of said sub-population. | 05-06-2010 |
Abdellah Benjahad, Champigny S/marne FR
| Patent application number | Description | Published |
|---|---|---|
| 20080242704 | Substituted Oxazole Derivatives and their Use as Tyrosine Kinase Inhibitors - The present invention relates to novel compounds selected from substituted oxazole derivatives of formula (I) that selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant tyrosine kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, allergic, and degenerative disorders. More particularly, these compounds are potent and selective c-kit, bcr-abl and Fit-3 inhibitors. | 10-02-2008 |
Abdellah Benjahad, Champigny Sur Marne FR
| Patent application number | Description | Published |
|---|---|---|
| 20090192317 | PROCESS FOR THE SYNTHESIS OF 2-AMINOXAZOLE COMPOUNDS - The present invention relates to a process for synthesizing in good yield substituted 2-aminoaryloxazole compounds of formula I which are useful as certain tyrosine kinase inhibitors and more particularly as c-kit, bcr-abl, Flt-3 and mutant forms thereof. | 07-30-2009 |
| 20100113471 | 2-Aminoaryloxazole compounds as tyrosine kinase inhibitors - The present invention relates to novel compounds selected from 2-aminoaryloxazoles that selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant tyrosine kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, allergic and degenerative disorders. More particularly, these compounds are potent and selective c-kit, bcr-abl, FGFR3 and/or Flt-3 inhibitors. | 05-06-2010 |
Abdellah Mourchid, East Boston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080231304 | Apparatus and method for controlling temperature in a chuck system - An apparatus and method of controlling the temperature of a thermal chuck system are disclosed. The system includes a temperature controller which controls a temperature transition in a thermal chuck. The temperature controller comprises inputs that receive air and fluid from an air source and water source, respectively, and an output for alternately transferring the air and fluid in proportions to the thermal chuck. A time proportional controller generates the proportions by computing a proportion band in each of a plurality of control regions. The proportion bands are used by the temperature controller to manage the flow of air and fluid to the chuck such that a minimum undershoot of the temperature transition is realized. | 09-25-2008 |
Abdellah Sentissi, Dover, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090304592 | TREATMENT OF METASTATIC TUMORS - The present invention is directed to methods and methods for the treatment, inhibition and/or reduction, and detection of metastatic tumors. In some embodiments, the inventive methods include systemic (e.g., intravenous) administration of a chlorotoxin agent that may or may not be labeled. In some embodiments, the inventive methods allow treatment, inhibition and/or reduction, and detection of metastases in the brain. In some embodiments, neovascularization is inhibited and/or newly formed vessels are caused to regress. | 12-10-2009 |
| 20110027177 | INHIBITION OF ANGIOGENESIS - The present invention is directed to novel methods of inhibiting angiogenesis using chlorotoxin agents. In some embodiments, the inventive methods include intravenous, intraocular, intravitreal, subjunctival injection, and/or topical administration of a chlorotoxin agent that may or may not be labeled. In some embodiments, the inventive methods allow treatment and/or amelioration of ocular diseases characterized by neovascularization, such as wet macular degeneration. In some embodiments, neovascularization is inhibited and/or newly formed vessels are caused to regress. | 02-03-2011 |
| 20110091380 | CHLOROTOXINS AS DRUG CARRIERS - The present invention relates to the use of a toxin moiety (e.g., a chlorotoxin moiety) as a carrier for therapeutic agents, e.g., therapeutic agents that require intracellular uptake to exert their effects. For example, in some embodiments, the present invention provides conjugates comprising a toxin (e.g., a chlorotoxin) moiety and an anti-cancer moiety and methods for using such conjugates to increase cellular uptake and/or increase specificity for cancer cells of the anti-cancer drug. In some embodiments, the present invention provides conjugates comprising a toxin moiety (e.g., a chlorotoxin moiety) and a nucleic acid agent. Also provided are methods of treatment involving administration of such conjugates, and pharmaceutical compositions and kits useful for carrying out such methods of treatment. | 04-21-2011 |
Abdellah Tahri, Heverlee BE
| Patent application number | Description | Published |
|---|---|---|
| 20100029632 | BROADSPECTRUM 2-AMINO-BENZOXAZOLE SULFONAMIDE HIV PROTEASE INHIBITORS - The present invention concerns the compounds having the formula | 02-04-2010 |
Abdellah Talamali, Legnaro IT
| Patent application number | Description | Published |
|---|---|---|
| 20100089812 | FILTER CARTRIDGE ASSEMBLY - A filter assembly ( | 04-15-2010 |