Aashish
Aashish Goela, Barrington, IL US
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20150146950 | METHODS AND APPARATUS TO ESTIMATE VENTRICULAR VOLUMES - Methods and apparatus to estimate ventricular volumes are disclosed. An example computer-implemented method includes preparing a sample set using a prior probability model for a left ventricle and a right ventricle and using a likelihood function to assign a weight to each sample within the sample set. The example method also includes, based on the weighted sample set, determining an area of the right ventricle and the left ventricle. | 05-28-2015 |
Aashish Manglik, Menlo Park, CA US
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20150355200 | Method for Selecting Agents that Bind to Transmembrane Receptors in a Conformationally-Selective Manner - Provided herein are several methods for selecting agents that bind to transmembrane receptors in a conformationally-selective way. In some embodiments, the method may comprise producing: a transmembrane receptor in an active conformation; and said transmembrane receptor in an inactive conformation and using cell sorting to select, from a population of cells comprising a library of cell surface-tethered extracellular capture agents, cells that are specifically bound to either the transmembrane receptor in its active conformation or the transmembrane receptor in its inactive conformation, but not both. In other embodiments, the method may comprise: contacting a GPCR with a population of cells that comprise a library of surface-tethered extracellular proteins; labeling the cell population with a conformationally-specific binding agent, e.g., a G-protein or mimetic thereof; and using cell sorting to select from the cell population cells that bind to the agent. | 12-10-2015 |
20150368339 | MUSCARINIC ACETYLCHOLINE RECEPTOR BINDING AGENTS AND USES THEREOF - Agents that specifically bind to a muscarinic acetylcholine receptor in a conformationally-specific way can be used to induce a conformational change in the receptor. Such agents have therapeutic applications and can be used in X-ray crystallography studies of the receptor. Such agents can also be used to improve drug discovery via compound screening and/or structure based drug design. | 12-24-2015 |
Aashish Pangam, Mumbai IN
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20150145875 | COMMAND SCHEDULER FOR A DISPLAY DEVICE - Systems and methods consistent with the present disclosure may be utilized to negate the distinction between a display device operating in video and command modes in that commands associated with either mode are prioritized and executed according to a command scheduler consistent with the present disclosure. A command scheduler consistent with the present disclosure includes a display driver stack and a scheduler coupled to the display driver stack. The scheduler is configured to receive commands from the driver stack. Further, the scheduler is configured to queue and schedule the commands to be executed during a boot environment and during runtime. A host controller may also be coupled to the scheduler and may receive at least one of the commands from the scheduler. In time, the host controller transfers the commands to a device for execution. | 05-28-2015 |
Aashish Priye, Bryan, TX US
Aashish Wadke, Stoughton, WI US
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20100132322 | APPARATUS, SYSTEM, AND METHOD FOR INSULATING AN EXHAUST AFTERTREATMENT COMPONENT - According to one representative embodiment, an exhaust aftertreatment component that includes a housing that defines an interior cavity through which exhaust gas is flowable. The housing includes an inner body, an outer body, and a space defined between the inner and outer bodies. The component also includes an insulation pack that is positioned within the space. The insulation pack includes insulation media encapsulated by a flexible fabric. The insulation pack further includes an at least partially rigid member that has a rigidity greater than a rigidity of the insulation media and flexible fabric. | 06-03-2010 |
20130330237 | AFTERTREATMENT MANIFOLD DEVICE - An aftertreatment subsystem includes first and second mounting interfaces, a fluid inlet and fluid outlet interface, and aftertreatment components, each having a central axis and axial extent. The central axes for the aftertreatment components are substantially parallel. End caps define fluid chambers that fluidly couple upstream aftertreatment component outlets with downstream aftertreatment components inlets. The end caps are positioned at a first or second end of the aftertreatment components. A first bracket joins the aftertreatment components at an axial position closer to the first end than to a center of the axial extent of any of the aftertreatment components and a second bracket joins the aftertreatment components at an axial position closer to the second end than to the center of the axial extent of any of the aftertreatment components. The first mounting interface is on the first bracket, and the second mounting interface is on the second bracket. | 12-12-2013 |