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Aaron Smith

Aaron Smith, Portland, OR US

Patent application numberDescriptionPublished
20110087737SYSTEMS AND METHODS FOR LIVING USER REVIEWS - Systems and methods for creating an opinion timeline. Users are able to submit ongoing reviews for products and services based on extended use, new revelations, additional features, upgrades and the like. Users can be notified of upgrades or improvements and are requested to provide another review of the product or service which is tied to the original review. Users can also update their review of the product or service based on a change in mind. The opinion timeline can be applied to reviews of products, television shows, music, etc.04-14-2011

Aaron Smith, Emeryville, CA US

Patent application numberDescriptionPublished
20100048547PI 3-KINASE INHIBITORS AND METHODS OF THEIR USE - Phosphatidylinositol (PI) 3-kinase inhibitor compounds, their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases, including proliferative diseases, inflammatory and obstructive airways diseases, allergic conditions, autoimmune and cardiovascular diseases.02-25-2010
20100075965PI3 KINASE INHIBITORS AND METHODS OF THEIR USE - Phosphatidylinositol (PI) 3 kinase inhibitor compounds, their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, phospholipid kinases, G-protein coupled receptors, and phosphatases.03-25-2010
20100249126PYRIMIDINE DERIVATIVES USED AS PI-3-KINASE INHIBITORS - Phosphatidylinositol (PI) 3-kinase inhibitor compounds (I), their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases.09-30-2010

Aaron Smith, Union City, CA US

Patent application numberDescriptionPublished
20100003246Novel heterocyclic compounds and uses therof - New substituted heterocyclic compounds, compositions containing them, and methods of using them for the inhibition of Raf kinase activity are provided. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.01-07-2010
20100105654SUBSTITUTED QUINAZOLINONE COMPOUNDS - A variety of small molecule, guanidine-containing molecules capable of acting as MC4-R agonists are provided. The compounds are useful in treating MC4-R mediated diseases when administered to subjects. The compounds have the structures VA, VB, VIIA and VIIB where the values of the variables are defined herein.04-29-2010

Patent applications by Aaron Smith, Union City, CA US

Aaron Smith, Denver, CO US

Patent application numberDescriptionPublished
20090287443Method for Calibrating a Navigation System - A method and apparatus for electromagnetic navigation of a surgical probe near a metal object. The electromagnetic navigation system includes a transmitter coil array and a shield. The transmitter coil array has a plurality of transmitter coils and is operable to generate the electromagnetic field to navigate the probe. The shield is positioned adjacent the metal object and is operable to shield the metal object from the electromagnetic field generated by the transmitter coil array, such that the shield substantially reduces distortion of the electromagnetic field by the metal object.11-19-2009

Aaron Smith, Dallas, TX US

Aaron Smith, Warsaw, IN US

Patent application numberDescriptionPublished
20120078375VARIABLE PROSTHESIS - The present teachings are directed to a shoulder prosthesis having an adjustable radial offset and/or angular inclination provided by relative rotation of an adapter interdisposed between a stem and a head. In one example, a prosthesis has a stem having a first longitudinal axis. The prosthesis can also include an adaptor including a first taper. The first taper can have a first taper axis. The prosthesis can include a head supported by the adaptor. The head can be selectively oriented and then coupled to the first taper and the combination can be selectively orientated and the coupled to the stem.03-29-2012

Aaron Smith, Providence, RI US

Patent application numberDescriptionPublished
20120108619N1/N2-LACTAM ACETYL-COA CARBOXYLASE INHIBITORS - The invention provides a compound of Formula (I)05-03-2012