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Aaron D.
Aaron D. Cobabe, Syracuse, UT US
| Patent application number | Description | Published |
|---|---|---|
| 20080222822 | CLEANING APPARATUS WITH RECIPROCATING BRUSH HEAD - A cleaning apparatus includes an elongated housing bounding a chamber with a motor disposed therein. A drive shaft is at least partially disposed within the chamber of the housing, the drive shaft being coupled with the motor such that during selective operation of the motor the drive shaft is rotated continuously. A head assembly includes an elongated head housing having a head drive shaft and a brush head mounted thereon. The head assembly is adapted to be selectively coupled with the body assembly so that the body drive shaft is coupled with the head drive shaft. | 09-18-2008 |
| 20100017978 | CLEANING APPARATUS WITH RECIPROCATING BRUSH HEAD - A cleaning apparatus includes an elongated housing bounding a chamber with a motor disposed therein. A drive shaft is at least partially disposed within the chamber of the housing, the drive shaft being coupled with the motor such that during selective operation of the motor the drive shaft is rotated. A head assembly includes an elongated head housing having a head drive shaft and a brush head mounted thereon. The head assembly is adapted to be selectively coupled with the body assembly so that the body drive shaft is coupled with the head drive shaft. | 01-28-2010 |
| 20110047728 | CLEANING APPARATUS WITH RECIPROCATING BRUSH HEAD - A cleaning apparatus includes an elongated housing bounding a chamber with a motor disposed therein. A drive shaft is at least partially disposed within the chamber of the housing, the drive shaft being coupled with the motor such that during selective operation of the motor the drive shaft is rotated. A head assembly includes an elongated head housing having a head drive shaft and a brush head mounted thereon. The head assembly is adapted to be selectively coupled with the body assembly so that the body drive shaft is coupled with the head drive shaft. | 03-03-2011 |
Aaron D. Gitler, Philadelphia, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090099069 | MODULATORS OF ALPHA-SYNUCLEIN TOXICITY - Disclosed are compositions and methods for modulating expression of genes that function at the step of ER of Golgi trafficking. Compounds that modulate expression of these genes of activity of the encoded proteins can be used to inhibit alpha-synuclein mediated toxicity and used to threat of prevent synucleinopathies such as Parkinson's disease. Also disclosed are methods of identifying inhibitors of alpha-synuclein mediated toxicity. | 04-16-2009 |
| 20110053857 | YEAST CELLS EXPRESSING TAR DNA-BINDING PROTEIN 43 AND USES THEREFOR - Disclosed are yeast cells expressing TAR DNA-binding protein 43 (TDP-43) and methods of screening yeast cells to identify compounds that prevent or suppress TDP-43-induced toxicity, compounds that inhibit the formation or maintenance of cytoplasmic inclusions of TDP-43, genetic suppressors or enhancers of TDP-43-induced toxicity, and genetic suppressors or enhancers of the formation or maintenance of cytoplasmic inclusions of TDP-43. Compounds identified by such screens can be used to treat or prevent TDP-43 proteinopathies such as frontotemporal lobar degeneration or amyotrophic lateral sclerosis. | 03-03-2011 |
| 20110064722 | MODULATORS OF ALPHA-SYNUCLEIN TOXICITY - Disclosed are genes that, when overexpressed in cells expressing alpha-synuclein, either suppress or enhance alpha-synuclein mediated cellular toxicity. Compounds that modulate expression of these genes or activity of the encoded proteins can be used to inhibit alpha-synuclein mediated toxicity and used to treat or prevent synucleinopathies such as Parkinson's disease. Also disclosed are methods of identifying inhibitors of alpha-synuclein mediated toxicity. | 03-17-2011 |
| 20110142789 | Compositions and Methods for the Diagnosis and Treatment of Amyotrophic Lateral Sclerosis - Compositions and methods for diagnosis and treatment of ALS are provided. | 06-16-2011 |
Aaron D. Gitler, Quincy, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090304664 | MODULATORS OF ALPHA-SYNUCLEIN TOXICITY - Disclosed are genes that, when overexpressed in cells expressing alpha-synuclein, either suppress or enhance alpha-synuclein mediated cellular toxicity. Compounds that modulate expression of these genes or activity of the encoded proteins can be used to inhibit alpha-synuclein mediated toxicity and used to treat or prevent synucleinopathies such as Parkinson's disease. Also disclosed are methods of identifying inhibitors of alpha-synuclein mediated toxicity. | 12-10-2009 |
Aaron D. Pailes, Acton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090268871 | X-Ray Inspection with Contemporaneous and Proximal Transmission and Backscatter Imaging - An X-ray imaging inspection system for bags and packages. Transmission imaging is performed using a fan beam and a segmented detector, while scatter imaging is performed with a scanned pencil beam, with both beams active simultaneously. Cross-talk between the beams is mitigated by a combination of shielding, scatter detector design, positioning and orientation, and image processing. Image processing subtracts the measured radiation scattered from the transmission beam into the scatter detectors, reducing cross-talk | 10-29-2009 |
Aaron D. Pesnell, Cherry Hill, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100131037 | RADIOPAQUE POLYMERIC STENTS - The present invention relates to polymeric medical devices such as stents. More particularly the polymeric compositions disclosed herein comprise halogen-containing, tyrosine-derived diphenols, optionally in conjunction with other groups, such as dicarboxylic acids and/or poly(alkylene oxides), such that the medical devices made from these polymeric compositions are bioresorbable and inherently radiopaque, and exhibit physicomechanical properties consistent with the intended uses of such devices. | 05-27-2010 |
Aaron D. Pokowski, St. Clair Shores, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20100007156 | Glove box striker with box clip attachment feature - The present invention provides a striker with a box clip feature. The striker may be mounted to a support structure for engagement with a latch mechanism. The striker may include a body for mounting to a support structure, such as an instrument panel in a vehicle. The striker may include a latch bar capable of engaging the latch mechanism. The striker may also include a locating feature that may aid in alignment within the support structure for quick assembly. The box clip feature may include an aperture that is capable of connecting said body to the support structure. | 01-14-2010 |
Aaron D. Schilpp, Appleton, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20120035563 | Absorbent Articles with Intricate Graphics - Absorbent articles are disclosed that have been printed with active graphics alone or in combination with permanent graphics to create a wetness indicator. Different active graphic compositions and/or permanent graphic compositions are combined so as to make the wetness indicator very prominent on the article. In addition, when the absorbent article is wetted, the active graphics undergo a change that is easily noticed by the wearer or the caregiver for the wearer. In one embodiment, for instance, active graphics are positioned within a distinctive frame. The frame focuses a person's attention onto the active graphics. The active graphics fill most of the surface area of the frame such that when the absorbent article is wetted, a clearly noticeable change occurs. | 02-09-2012 |