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A. Michael

A. Michael Lincoff, Orange Village, OH US

Patent application numberDescriptionPublished
20100292134Method for inhibiting new tissue growth in blood vessels in a patient subjected to blood vessel injury - This invention provides for a method for inhibiting new tissue growth in blood vessels in a subject, wherein the subject experienced blood vessel injury, which comprises administering to the subject a pharmaceutically effective amount of an inhibitor of receptor for advanced glycation endproduct (RAGE) so as to inhibit new tissue growth in the subject's blood vessels. The invention also provides for method for inhibiting neointimal formation in blood vessels in a subject, wherein the subject experienced blood vessel injury, which comprises administering to the subject a pharmaceutically effective amount of an inhibitor of receptor for advanced glycation endproduct (RAGE) so as to inhibit neointimal formation in the subject's blood vessels. The invention also provides a method for preventing exaggerated restenosis in a diabetic subject which comprises administering to the subject a pharmaceutically effective amount of an inhibitor of receptor for advanced glycation endproduct (RAGE) so as to prevent exaggerated restenosis in the subject.11-18-2010

A. Michael Mondry, Nun'S Island CA

Patent application numberDescriptionPublished
20090100374METHOD AND SYSTEM FOR REFERENCED REGION MANIPULATION - A method and computer graphics program executed by one or more processors is described for arranging regions which refer to various parts of a graphical layout such that changes to the original layout result in updates to the said regions. The regions themselves may be arranged by the user in patterns for various purposes, such as condensing graphical content spread over many parts of the original layout into a single output page in order to minimize the consumption of ink and paper when printing.04-16-2009
20100066758SYSTEM AND METHOD FOR AUTOMATIC GENERATION OF IMAGE DISTRIBUTIONS - A method and system for automatically producing arrangements of two-dimensional extents in a computer-based editing or animation environment is presented. The method consists of defining a set of objects having two or more dimensions, automatically calculating and presenting an arrangement of said objects, and optionally iterating to produce alternative arrangements. The arrangements may use templates to guide the selection of sizes, border colors and transparency, rotation, and other attributes of the contained regions.03-18-2010

Patent applications by A. Michael Mondry, Nun'S Island CA

A. Michael Sismour, Cambridge, MA US

Patent application numberDescriptionPublished
20100081140CHEMICALLY CLEAVABLE PHOSPHORAMIDITE LINKERS FOR SEQUENCING BY LIGATION - Linkers and methods for determining a nucleotide sequence of a reference oligonucleotide are provided.04-01-2010
20100092988Methods and Compounds For Chemical Ligation - Compositions and methods for chemical ligation are provided. Methods for nucleic acid sequencing, nucleic acid assembly and nucleic acid synthesis are also provided.04-15-2010