Patent application number | Description | Published |
20140107994 | ENABLING REUSE OF UNIT-SPECIFIC SIMULATION IRRITATION IN MULTIPLE ENVIRONMENTS - In the verification of an electronic design such as a microprocessor, a set of generic transaction types is applied to a unit in a unit simulation environment and then the same set of generic transaction types is applied to the unit in a larger (e.g., element) simulation environment using an abstraction layer which can interface with both a unit translation layer of the unit simulation environment and an element translation layer of the element simulation environment. The abstraction layer may comprise a generic driver interface which issues generic commands having command parameters including a command type, an address, and operand data. The invention can be extended to multiple units which make up the element, or to multiple elements in the element environment. The invention can further be extended in a hierarchical fashion to other levels of simulation environments, e.g., unit-element-system. | 04-17-2014 |
20140107996 | ENABLING REUSE OF UNIT-SPECIFIC SIMULATION IRRITATION IN MULTIPLE ENVIRONMENTS - In the verification of an electronic design such as a microprocessor, a set of generic transaction types is applied to a unit in a unit simulation environment and then the same set of generic transaction types is applied to the unit in a larger (e.g., element) simulation environment using an abstraction layer which can interface with both a unit translation layer of the unit simulation environment and an element translation layer of the element simulation environment. The abstraction layer may comprise a generic driver interface which issues generic commands having command parameters including a command type, an address, and operand data. The invention can be extended to multiple units which make up the element, or to multiple elements in the element environment. The invention can further be extended in a hierarchical fashion to other levels of simulation environments, e.g., unit-element-system. | 04-17-2014 |
Patent application number | Description | Published |
20090156818 | Process and compounds for the production of (+)opiates - The invention generally provides processes and intermediate compounds useful for the production of (+)-opiates. Non-limiting examples of (+) opiates that may be derived from one or more compounds of the invention include (+)-noroxymorphone, (+)-naltrexone, (+)-naloxone, (+)-N-cyclopropylmethylnorhydrocodone, (+)-N-cycloproylmethylnorhydromorphone, (+)-N-allylnorhydrocodone, (+)-N-allylnorhydromorphone, (+)-noroxycodone, (+)-naltrexol, (+)-naloxol, and (+)-3-O-methyl-naltrexone. | 06-18-2009 |
20100317683 | Preparation of 6-Alpha-Amino N-Substituted Morphinans by Catalytic Hydrogen Transfer - The present invention provides processes for the stereoselective synthesis of 6-alpha-amino N-substituted morphinans. In particular, the invention provides processes for the reductive amination of 6-keto N-substituted morphinans by catalytic hydrogen transfer. | 12-16-2010 |
20100317861 | Remove Amination of 6-Keto Normorphinans by Catalytic Hydrogen Transfer - The present invention provides processes for the stereoselective synthesis of 6-alpha-amino morphinans. In particular, the invention provides processes for the reductive amination of 6-keto normorphinans by catalytic transfer hydrogenation. | 12-16-2010 |
20120316343 | Reductive Amination of 6-Keto Morphinans by Catalytic Hydrogen Transfer - The present invention provides compositions of 6-amino morphinan compounds and process for their synthesis. In particular, the processes provide for the reductive amination of 6-keto morphinans by catalytic transfer hydrogenation, to produce 6-amino morphinan compounds, which are epimerically and/or diastereomerically enriched. | 12-13-2012 |
20130144053 | Process for the Production of Seven-Membered Lactam Morphinans - The present invention relates to improved processes for preparing lactam morphinans. The processes generally transform keto-morphinans to seven-membered lactam morphinans using a hydroxyamine sulfonic acid reagent and proceed in high yield and with good selectivity. | 06-06-2013 |
Patent application number | Description | Published |
20120172897 | SUTURE SYSTEM AND ASSEMBLY INCLUDING A TUBULAR LEADER HAVING A CLASP - A suture system includes a tool and a suture assembly. The tool includes a head having a proximal portion housing a needle and a distal end spaced apart from the proximal portion by a throat. The needle is movable through a needle exit port formed in the proximal portion of the head to a cavity formed in the distal end of the head. The suture assembly includes a length of suture connected to a tubular leader. The tubular leader includes an annular wall extending between an interior surface and an exterior surface, and a clasp having a first portion disposed between the interior surface and the exterior surface of the annular wall and a second portion extending out of the annular wall and adapted to secure the suture against the annular wall. | 07-05-2012 |
20120197270 | SUTURE SYSTEM AND ASSEMBLY INCLUDING A LEADER PLUG - A suture system configured to place suture in tissue includes a tool and a suture assembly. The tool includes a head having a proximal portion housing a needle and a distal end spaced apart from the proximal portion. The needle is movable through a needle exit port formed in the proximal portion of the head to a cavity formed in the distal end of the head. The suture assembly has a length of suture connected to a leader plug, and the leader plug includes a substantially solid proximal portion. The leader plug is removably retained in the cavity formed in the distal end of the head and the needle is operable to penetrate and engage with the substantially solid proximal portion of the leader plug to allow the needle to extract the leader plug out of the cavity and secure the leader plug in the needle exit port. | 08-02-2012 |
20120209298 | SUTURE SYSTEM AND ASSEMBLY INCLUDING A SUTURE CLIP - One aspect provides a suture system including a tool and a suture assembly. The tool includes a head having a proximal portion housing a needle and a distal end spaced apart from the proximal portion by a throat, the needle is movable through a needle exit port formed in the proximal portion of the head to a cavity formed in the distal end of the head. The suture assembly includes suture connected to a suture clip that includes a cylindrical body having a proximal end and a distal end and a slot formed in the cylindrical body between the proximal end and the distal end that allows the cylindrical body to flex in a radial direction, a tab extending from the distal end and configured to be crimped onto an end of the length of suture, and a rib formed on an interior surface of the cylindrical body. | 08-16-2012 |
20120316581 | SPOOL CONFIGURED TO RETAIN SUTURE FOR A SUTURE SYSTEM - A suture system spool is configured to retain suture having a suture diameter and tension the suture between a distal and proximal end portions of a suturing tool. The spool includes a monolithically formed disc defining a central opening that provides the disc with an inside diameter. The disc includes a base and a flap joined with the base at the inside diameter, and the flap extends from the inside diameter to an outer periphery of the disc to define a cavity between the flap and the base. The flap is spaced away from the base at a location between the inside diameter and the outer periphery of the disc by a factor of at least two times the suture diameter, and the flap is spaced away from the base at the outer periphery of the disc by a distance that is approximately equal to the suture diameter. | 12-13-2012 |
20130281766 | METHOD OF TREATING INCONTINENCE AND TREATMENT DEVICE INCLUDING NON-POROUS CUFF AND EXTENDING MEMBERS - A method of treating urinary incontinence includes making an incision and exposing tissue of a urethra. The method additionally includes inserting a non-porous sheet into the incision and forming a cuff around the urethra with the non-porous sheet by directing a first end of the non-porous sheet through a slot formed in a second end of the non-porous sheet. The method additionally includes directing an extending member that is attached to the non-porous sheet to a location exterior of a pelvis. The method further includes configuring the cuff to tighten around the urethra when pulling on the first end of the non-porous sheet, and configuring the cuff to be loosely positioned around the urethra when pulling on the extending member. | 10-24-2013 |
20130281767 | INCONTINENCE TREATMENT DEVICE INCLUDING NON-POROUS CUFF AND EXTENDING MEMBERS - An incontinence treatment device includes a non-porous support and an extending member. The non-porous support has a first end portion provided with a slot and a second end portion. The second end portion is insertable through the slot to form a cuff that is configured for placement around a urethra of a user. The extending member is attached to the support at a junction located between the first end portion and the second end portion. Tension applied to the second end portion is adapted to draw the junction toward the slot to tighten the cuff and thus provide the user with a continent state. Tension applied to the extending member is adapted to draw the juncture away from the slot and expand the cuff and thus allow the user to urinate. | 10-24-2013 |
20130282030 | SUTURING SYSTEM AND ASSEMBLY - A suturing assembly is provided that is configured to pull a capsule attached to a suture through tissue. The suturing assembly includes a shaft aligned on a longitudinal axis of the suturing assembly, and a head coupled to the shaft. The head includes a proximal portion and a distal end spaced apart from the proximal portion by a throat. The proximal portion houses a needle that is movable through a needle exit port. The proximal portion of the head and the needle exit port are both aligned on the longitudinal axis. A proximal side of the distal end of the head defines a cavity adapted to receive the capsule and a distal side of the distal end of the head defines a slot adapted to allow the suture to pass through the distal end of the head and into the cavity. | 10-24-2013 |
20130296638 | INCONTINENCE TREATMENT DEVICE INCLUDING NON-POROUS SUB-URETHRAL SLING - An incontinence treatment device includes a non-porous sub-urethral sling provided with an adjustment device. The device includes first and second anchors coupled to the sling. The second anchor includes a channel formed through the second anchor and a restrictor segment provided in the channel. The adjustment device is movable through the channel formed through the second anchor. The resistor segment is configured to resist movement of the adjustment device through the channel. | 11-07-2013 |
20130299625 | SPOOL CONFIGURED TO RETAIN SUTURE FOR A SUTURE SYSTEM - A suture system spool is configured to retain suture having a suture diameter and tension the suture between a distal and proximal end portions of a suturing tool. The spool includes a monolithically formed disc defining a central opening that provides the disc with an inside diameter. The disc includes a base and a flap joined with the base at the inside diameter, and the flap extends from the inside diameter to an outer periphery of the disc to define a cavity between the flap and the base. The flap is spaced away from the base at a location between the inside diameter and the outer periphery of the disc by a factor of at least two times the suture diameter, and the flap is spaced away from the base at the outer periphery of the disc by a distance that is approximately equal to the suture diameter. | 11-14-2013 |
20140100418 | MAGNETIC INCONTINENCE TREATMENT DEVICE - An incontinence treatment device includes a band attached to a pendant. The band is implantable around a portion of a urethra and has a first magnet connected to a first end portion of the band and a second magnet connected to a second end portion of the band. The pendant is connected to and extends from the band. The pendant has a shape that configures the pendant to be implantable into a scrotum and a thickness that configures the pendant to be implantable into a labia. The pendant encloses a switch and a power source that are electrically coupled to the first magnet and the second magnet. The switch has an on position to constrict the band around the urethra and an off position in which substantially zero current is provided to decouple the first magnet from the second magnet. | 04-10-2014 |
20140128665 | INCONTINENCE TREATMENT DEVICE INCLUDING NON-POROUS SUB-URETHRAL SLING - An incontinence treatment device includes a non-porous sling located between two anchors. A first line is attached between a first end of the sling and the first anchor, and a second line is attached to a second end of the sling and inserted through a channel of the second anchor. The second anchor is provided with a restrictor segment provided in the channel. The second line has an adjustment device attached to the second line and the restrictor segment is configured to resist movement of the adjustment device through the channel. The adjustment device is movable through the channel from a first position that locates the adjustment device between the second anchor and the sling to a second position that locates the second anchor between the adjustment device and the sling to thereby reduce an effective length of the sling between the first and second anchors. | 05-08-2014 |
20150018852 | METHOD OF PLACING SUTURE THROUGH TISSUE WITH A FINGER GUIDED SUTURING DEVICE - A method of placing a suture through tissue includes placing a band on a finger of a user, where the band is attached to a head of a suturing device, and employing the finger and the device in identifying an intracorporeal tissue landmark and placing the head of the suturing device at the intracorporeal tissue landmark. The method additionally includes engaging a throat of the head of the suturing device with the intracorporeal tissue landmark, and ejecting a needle out of a needle exit port and through the tissue. The needle exit port is located on a proximal portion of the head of the suturing device. | 01-15-2015 |
20150080646 | METHOD OF TREATING INCONTINENCE - A method of treating incontinence includes implanting the incontinence treatment device having a sling connected between first and second anchors into a patient, and moving an adjustment device through a channel from a first position to a second position that locates the second anchor between the adjustment device and the sling, thus tightening the sling by shortening an effective distance of the device between the first and second anchors. | 03-19-2015 |