Chen, FL
Alan Chen, Windermere, FL US
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20130106535 | HIGH COUPLING, LOW LOSS SAW FILTER AND ASSOCIATED METHOD | 05-02-2013 |
Alan S. Chen, Windermere, FL US
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20080237642 | Method to Reduce Boron Penetration in a SiGe Bipolar Device - The invention, in one aspect, provides a method of manufacturing a semiconductor device. This aspect includes forming gate electrodes in a non-bipolar transistor region of a semiconductor substrate, placing a polysilicon layer over the gate electrodes in the non-bipolar transistor region and over the semiconductor substrate within a bipolar transistor region. A protective layer is formed over the polysilicon layer. The protective layer has a weight percent of hydrogen that is less than about 9% and is selective to silicon germanium (SiGe), such that SiGe does not form on the protective layer. This aspect further includes forming emitters for bipolar transistors in the bipolar transistor region, including forming a SiGe layer under a portion of the polysilicon layer. | 10-02-2008 |
20090050977 | METHOD TO REDUCE BORON PENETRATION IN A SiGe BIPOLAR DEVICE - The invention, in one aspect, provides a method of manufacturing a semiconductor device. This aspect includes forming gate electrodes in a non-bipolar transistor region of a semiconductor substrate, placing a polysilicon layer over the gate electrodes in the non-bipolar transistor region and over the semiconductor substrate within a bipolar transistor region. A protective layer is formed over the polysilicon layer. The protective layer has a weight percent of hydrogen that is less than about 9% and is selective to silicon germanium (SiGe), such that SiGe does not form on the protective layer. This aspect further includes forming emitters for bipolar transistors in the bipolar transistor region, including forming a SiGe layer under a portion of the polysilicon layer. | 02-26-2009 |
20100065920 | METHOD TO REDUCE COLLECTOR RESISTANCE OF A BIPOLAR TRANSISTOR AND INTEGRATION INTO A STANDARD CMOS FLOW - The invention, in one aspect, provides a method for fabricating a semiconductor device. In one aspect, the method provides for a dual implantation of a tub of a bipolar transistor. The tub in bipolar region is implanted by implanting the tub through separate implant masks that are also used to implant tubs associated with MOS fabricate different voltage devices in a non-bipolar region during the fabrication of MOS transistors. | 03-18-2010 |
20100102418 | BIPOLAR DEVICE HAVING IMPROVED CAPACITANCE - The invention, in one aspect, provides a semiconductor device that comprises a collector located in a semiconductor substrate and an isolation region located under the collector, wherein a peak dopant concentration of the isolation region is separated from a peak dopant concentration of the collector that ranges from about 0.9 microns to about 2.0 microns. | 04-29-2010 |
20110204747 | Temperature Compensated Surface Acoustic Wave Device and Method Having Buried Interdigital Transducers for Providing an Improved Insertion Loss and Quality Factor - A SAW device having metal electrodes on a surface of the piezoelectric substrate includes a dielectric layer deposited on the surface. Depositing the layer results in seams extending upward from the electrodes extending above the surface of the substrate. An additional seam results from one seam extending from one electrode joining a second seam extending from an adjacent electrode within the dielectric layer and is generally formed above the height of the electrodes. The additional seam is removed through planarization or the like. The dielectric layer may be further planarized for providing a thickness of the dielectric layer above the electrodes as desired. | 08-25-2011 |
20120161577 | Acoustic Wave Guide Device and Method for Minimizing Trimming Effects and Piston Mode Instabilities - An acoustic wave device operable as a piston mode wave guide includes electrodes forming an interdigital transducer on a surface of the piezoelectric substrate, wherein each of the plurality of electrodes is defined as having a transversely extending center region and transversely opposing edge regions for guiding an acoustic wave longitudinally through the transducer. A Silicon Oxide overcoat covers the transducer and a Silicon Nitride layer covers the Silicon Oxide overcoat within only the center and edge regions. The thickness of the Silicon Nitride layer is sufficient for providing a frequency modification to the acoustic wave within the center region and is optimized with a positioning of a Titanium strip within each of the opposing edge regions. The Titanium strip reduces the acoustic wave velocity within the edge regions with the velocity in the edge regions being less than the wave velocity within the transducer center region. | 06-28-2012 |
20140252916 | ACOUSTIC WAVE DEVICE - Embodiments described herein may provide an acoustic wave device, a method of fabricating an acoustic wave device, and a system incorporating an acoustic wave device. The acoustic wave device may include a transducer disposed on a substrate, with a contact coupled with the transducer. The acoustic wave device may further include a wall layer and cap that define an enclosed opening around the transducer. A via may be disposed through the cap and wall layer over the contact, and a top metal may be disposed in the via. The top metal may form a pillar in the via and a pad on the cap above the via. The pillar may provide an electrical connection between the pad and the contact. In some embodiments, the acoustic wave device may be formed as a wafer-level package on a substrate wafer. | 09-11-2014 |
Alan S. Chen, Windermore, FL US
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20090236668 | METHOD TO IMPROVE WRITER LEAKAGE IN SiGe BIPOLAR DEVICE - The invention, in one aspect, provides a method for fabricating a semiconductor device, which includes conducting an etch through an opening in an emitter layer to form a cavity from an underlying oxide layer that exposes a doped tub. A first silicon/germanium (SiGe) layer, which has a Ge concentration therein, is formed within the cavity and over the doped tub by adjusting a process parameter to induce a strain in the first SiGe layer. A second SiGe layer is formed over the first SiGe layer, and a capping layer is formed over the second SiGe layer. | 09-24-2009 |
Alan Sangone Chen, Windermere, FL US
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20100032766 | Bipolar Junction Transistor with a Reduced Collector-Substrate Capacitance - A process for forming a bipolar junction transistor (BJT) in a semiconductor substrate and a BJT formed according to the process. A buried isolation region is formed underlying BJT structures to isolate the BJT structures from the p-type semi-conductor substrate. To reduce capacitance between a BJT subcollector and the buried isolation region, prior to implanting the subcollector spaced-apart structures are formed on a surface of the substrate. The subcollector is formed by implanting ions through the spaced-apart structures and through a region intermediate the spaced-apart structures. The formed BJT subcollector therefore comprises a body portion and end portions extending therefrom, with the end portions disposed at a shallower depth than the body portion, since the ions implanting the end portions must pass through the spaced-apart structures. The shallower depth of the end portions reduces the capacitance. | 02-11-2010 |
Chih Ming Chen, Davie, FL US
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20100278926 | Controlled Release Oral Dosage Form - A once a day bupropion salt formulation is disclosed. | 11-04-2010 |
Ching-Jen Chen, Tallahassee, FL US
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20100099941 | METHOD OF HYPERTHEMIA TREATMENT - Magnetic nanoparticle compositions are provided which provide an inherent temperature regulator for use in magnetic heating, particularly for use in magnetic hyperthermia medical treatments. The composition includes magnetic nanoparticles having a Curie temperature of between 40 and 46° C., preferably about 42° C., and may further include a polymeric material and optionally a drug or radiosensitizing agent. Methods of hyperthermia treatment of a patient in need thereof are provided which include administering to the patient a composition comprising magnetic nanoparticles having a Curie temperature of between 40 and 46° C.; and exposing the magnetic nanoparticles in the patient to an alternating magnetic field effective to generate hysteresis heat in the nanoparticles. | 04-22-2010 |
Christopher Chen, Weston, FL US
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20150100344 | PATIENT HEALTH INFORMATION ANALYSIS SYSTEM - Systems, methods, and computer-readable media for analyzing health information to generate medical assessments are described. Health information may include any type of information associated with the health or physical characteristics of a patient. Non-limiting examples of medical assessments include medical diagnoses, medical orders, and risk assessments. A health information analysis system may access health information associated with a patient and provide a medical assessment based on various analyses of the health information. The health information analysis system may receive feedback associated with the medical assessments, such as historical information and/or user input regarding the accuracy or completeness of the medical assessment. The feedback may be used by the health information analysis system to update the analyses of the health information. | 04-09-2015 |
Danny H. Chen, Miami, FL US
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20130166498 | Model Based OLAP Cube Framework - Systems, methods and computer program products that provide a framework for the creation, editing, manipulation and use of model-based, multidimensional analysis services (MAS) cubes are disclosed. A method of generating a model-based MAS cube comprises creating a data source comprising a data warehouse in the memory via the processor, creating a data source view providing a dimension, a fact and an outrigger from the created data source, and creating the MAS cube comprising at least one measure group. A key performance indicator (KPI) may be calculated from the MAS cube as a scorecard of a display associated with the processor. A user of the model-based MAS cube may create a new cube by targeting a set of facts and adding dimensions to the facts. | 06-27-2013 |
20130238549 | Using Dimension Substitutions in OLAP Cubes - Systems, methods and computer program products that provide a framework for the creation, editing, manipulation and use of model-based, multidimensional analysis services (MAS) cubes and using substitute dimensions in such cubes are disclosed. To permit a user to obtain better and automatic access to business intelligence, a method of generating a model-based MAS cube comprises creating a data source comprising a data warehouse in the memory via the processor, creating a data source view providing a dimension, a fact and an outrigger from the created data source, and creating the MAS cube comprising at least one measure group. Using substitute dimensions comprises finding all relevant substitutions for a measure group, creating a table for the measure group in the data source view, adding a property as the primary key of the substitute dimension and generating a query containing an inner join logical link between the substitute and original dimension. | 09-12-2013 |
Dung-Tsa Chen, Tampa, FL US
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20110039723 | MALIGNANCY-RISK SIGNATURE FROM HISTOLOGICALLY NORMAL BREAST TISSUE - The invention provides for malignancy-risk gene signatures that predict the risk of developing breast cancer, the recurrence of breast cancer, and/or the metastasis of breast cancer. These signatures have numerous clinical applications including assessing risk of breast cancer development following routine breast biopsy, assessing the need for adjuvant radiotherapy after lumpectomy, and determining the need for completion mastectomy following lumpectomy for the breast cancer patient and other treatment plans that are personalized for the patient. | 02-17-2011 |
20110046002 | Seven Gene Breast Cancer Predictor - The invention provides a molecular marker set that can be used for prognosis of breast cancer in a patient using histologically normal tissue. The invention also provides methods for evaluating prognosis of breast cancer in a patient based on a molecular molecular signature. | 02-24-2011 |
20110166095 | CANCER PLATINUM RESISTANCE DETECTION AND SENSITIZATION METHOD - The phosphorylation status of the BAD protein is a determinant of ovarian cancer cell responsiveness to platinum chemotherapy. Indirect manipulation of BAD phosphorylation status influences cisplatin sensitivity. BAD phosphorylation represents a biomarker that predicts platinum sensitivity and is a therapeutic target to increase platinum sensitivity. The methods employ phospho-specific antibody against a particular amino acid residue or site. Phospho-specific protein characterization methods include immunohistochemical (IHC), flow cytometric, immunofluorescent, capture-and-detection, or reversed phase assay. | 07-07-2011 |
20120322687 | METHODS OF PREDICTING HIGH GRADE GLIOMAS USING SENESCENCE ASSOCIATED GENES - The present invention relates to biomarkers for neoplasias such as high grade gliomas. The inventors have discovered that the overexpression of senescence associated genes (SAG) is associated with a poor prognosis in subjects with high grade gliomas. The present invention provides SAG biomarkers for predicting response to therapy for subjects having high grade glioma based on dividing the samples into high and low risk groups; diagnosing high grade glioma; monitoring progression of high grade glioma from one biological state to another; and determining efficacy of treatment for high grade gliomas. | 12-20-2012 |
20130011393 | BAD PATHWAY GENE SIGNATURE - The invention provides materials and methods for prognosing cancer, and predicting an individual's responsiveness to cancer treatments, methods of treating cancer, and materials and methods for obtaining BAD pathway gene expression profiles useful in carrying out the methods of the invention. | 01-10-2013 |
20130252831 | METHOD OF DIAGNOSING EARLY STAGE NON-SMALL CELL LUNG CANCER - A “malignancy-risk” (MR) gene signature score was developed with abundant proliferative genes using principal component analysis. This MR gene signature was shown to be a predictive and prognostic factor of overall survival in early-stage NSCLC. The malignancy-risk signature showed a significant association with OS, with poor survival seen in patients having a higher MR score and better survival seen in patients having a low MR score. As a prognostic factor, the MR gene signature showed a positive correlation with TNM stage, histologic grade, and smoking status. Combination of the MR signature with each clinical parameter often showed the best survival in the low MR group with good clinical outcome. The MR gene profile, tested with a PCA scoring method, discriminated overall survival in lung cancer patients was a predictor independent of pathological staging and other clinical parameters. | 09-26-2013 |
20140017703 | BAD PHOSPHORYLATION DETERMINES OVARIAN CANCER CHEMO-SENSITIVITY AND PATIENT SURVIVAL - Despite initial sensitivity BAD-protein phosphorylation were evaluated in patient samples and cell lines as determinants of chemo-sensitivity and/or clinical outcome, and as therapeutic targets. Induced in-vitro OVCA cisplatin-resistance was associated with BAD-pathway expression. Expression of the pathway was also associated with resistance of 7 different cancers cell-types to 8 chemotherapeutic agents. Phosphorylation of the BAD-protein was associated with platinum-resistance in OVCA cells and primary OVCA specimens, and also overall patient survival. Targeted modulation of BAD-phosphorylation levels influenced cisplatin-sensitivity. A 47-gene BAD-pathway signature was associated in-vitro phospho-BAD levels and with survival of 838 patients with ovarian, breast, colon, and brain cancer. The survival advantage associated with both BAD-phosphorylation and also the BAD-pathway signature was independent of surgical cytoreductive status. The BAD apoptosis pathway influences human cancer chemo-sensitivity and overall survival. The pathway is useful as a biomarker of therapeutic response, patient survival, and therapeutic target. | 01-16-2014 |
20140302060 | Gene Signature for the Prediction of NF-kappaB Activity - Methods for predicting NF-kappaB (NF-kB) activity in a tumor, and more particularly to methods for predicting survival and therapeutic outcome, and selecting therapy in subjects with tumors, e.g., adenocarcinomas, e.g., lung adenocarcinomas and melanomas. | 10-09-2014 |
20150376713 | BIOMARKERS AND METHODS FOR PREDICTING BENEFIT OF ADJUVANT CHEMOTHERAPY - Biomarkers, methods, assays, and kits are provided for predicting the efficacy of adjuvant chemotherapy (ACT) in a subject with early-stage non-small cell lung cancer (NSCLC). | 12-31-2015 |
Edward F. Chen, Sarasota, FL US
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20110265091 | SYSTEM AND METHOD FOR NORMALIZING JOB PROPERTIES - This disclosure provides a system and method for normalizing job properties. In one embodiment, a job manager is operable to identify a property of a job, with the job being associated with an operating environment. The job manager is further operable to normalize the property of the job and present the normalized property of the job to a user. | 10-27-2011 |
20110314474 | HETEROGENEOUS JOB DASHBOARD - This disclosure provides a system and method for summarizing jobs for a user group. In one embodiment, a job manager is operable to identify a state of a first job, the first job associated with a first job scheduler. A state of a second job is identified. The second job is associated with a second job scheduler. The first job scheduler and the second job scheduler are heterogeneous. A summary of information associated with at least the first job scheduler and the second job scheduler is determined using, at least in part, the first job state and the second job state. The summary is presented to a user though a dashboard. | 12-22-2011 |
Frank Bor-Her Chen, Lakeland, FL US
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20150275069 | ATTRITION RESISTANT PROPPANT COMPOSITE AND ITS COMPOSITION MATTERS - A hydraulic fracturing and gravel packing proppant composite with protectant on the surface of the proppant and the composition matters of the protectant and proppant. The surface protectant reduces the generation of dust/fines from the proppant caused by abrasion and impingement during transportation and conveyance, particularly pneumatic transfer. | 10-01-2015 |
20150275071 | ATTRITION RESISTANT PROPPANT COMPOSITE AND ITS COMPOSITION MATTERS - A hydraulic fracturing and gravel packing proppant composite with protectant on the surface of the proppant and the composition matters of the protectant and proppant. The surface protectant reduces the generation of dust/fines from the proppant caused by abrasion and impingement during transportation and conveyance, particularly pneumatic transfer. | 10-01-2015 |
Guangren Chen, Palm Harbor, FL US
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20100228138 | SYSTEM AND METHOD FOR SCANNING THE HEART - A system and method of testing a patient for coronary disease in the patient's heart is disclosed that comprises a microprocessor which contains a signal processor and a pattern recognition processor; means to detect the electrical signals of the heart whereby the signals are processed to create a pattern that represents the patient's heart. The pattern may be further processed by repeatedly comparing it to patterns stored within the pattern recognition processor whereby certain coronary diseases such as myocardial ischemia in the patient's heart may be diagnosed. During each heartbeat, at least a million different electrical impulses are collected and the results of the test are displayed on a screen. The results may include the diagnosis, computer generated image of the patient's heart identifying areas of any coronary disease that has been detected and/or a two dimensional waveform representing the electrical impulses of the patient's heart will be shown. In a further embodiment, the system will also generate ECG waveforms. to create vectors which represent the different directions of the muscle activity of the heart. | 09-09-2010 |
Guangren Chen, Palm Harboor, FL US
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20100261991 | Apparatus for wire or wireless ECG machine with only two leads - A disposable “Enhance Dynamic Flow Data” electrode, including: a flexible strips EDFD electrode and leads cable and voltage socket. Electrode with affixed program micro control chip, the chip having a positioned inside, the strips electrode have six electrode on one electrode with (V | 10-14-2010 |
20110263995 | Comprehensive Myocardial Repolarization Capture Wave-Format Method - A method of displaying a cardiac cycle of a heart into a three set colorable waveform comprising a plurality electrocardiography data taken over a period of time, said cardiac cycle information comprising a P wave, a PR segment, a QRS complex, and a ST segment, the method comprising generating a first wave hump by recalculating said P wave by using the Time-Frequency domain to determine an influxes of data compensation; generating a second wave hump by recalculating said PR segment by using integral formulaic expressions; generating a third wave hump by recalculating said QRS complex and said ST segment by using Hilbert space in the inner product. | 10-27-2011 |
Hai-Wen Chen, Orlando, FL US
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20100253855 | CONTINUOUS EXTENDED RANGE IMAGE PROCESSING - Methods and systems for image processing are provided. A method for processing images of a scene includes receiving image data of a reference and a current frame; generating N motion vectors that describe motion of the image data within the scene by computing a correlation function on the reference and current frames at each of N registration points; registering the current frame based on the N motion vectors to produce a registered current frame; and updating the image data of the scene based on the registered current frame. Optionally, registered frames may be oversampled. Techniques for generating the N motion vectors according to roll, zoom, shift and optical flow calculations, updating image data of the scene according to switched and intermediate integration approaches, re-introducing smoothed motion into image data of the scene, re-initializing the process, and processing images of a scene and moving target within the scene are provided. | 10-07-2010 |
20100254572 | CONTINUOUS EXTENDED RANGE IMAGE PROCESSING - Methods and systems for image processing are provided. A method for processing images of a scene includes receiving image data of a reference and a current frame; generating N motion vectors that describe motion of the image data within the scene by computing a correlation function on the reference and current frames at each of N registration points; registering the current frame based on the N motion vectors to produce a registered current frame; and updating the image data of the scene based on the registered current frame. Optionally, registered frames may be oversampled. Techniques for generating the N motion vectors according to roll, zoom, shift and optical flow calculations, updating image data of the scene according to switched and intermediate integration approaches, re-introducing smoothed motion into image data of the scene, re-initializing the process, and processing images of a scene and moving target within the scene are provided. | 10-07-2010 |
Harry Chen, Tallahassee, FL US
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20160126023 | HIGH PERFORMANCE LITHIUM-ION CAPACITOR LAMINATE CELLS - The present invention provides for high performance lithium-ion capacitor laminate cells that include positive electrodes, negative electrodes and organic solvent electrolyte with lithium salt, and a method for making said high performance lithium-ion capacitor laminate cells. These high performance lithium-ion capacitor laminate cells of the present invention, include a negative electrode which is pre-doped with sufficient lithium ions by employing lithium sources including lithium powder known as SLMP or thin lithium films on the surface of negative electrodes, and this pre-doping with placing lithium sources on negative electrode surface results in LIC laminate cells with considerably higher performance in specific energy, specific power and cycle life. | 05-05-2016 |
Huan Chen, Tallahassee, FL US
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20120276054 | Alternative bacterial treatment - Alternative treatments are provided for use in the inhibition, decrease, therapeutic or prophylactic support of a | 11-01-2012 |
Hul Chen, Gainesville, FL US
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20090239762 | APTAMERS THAT BIND ABNORMAL CELLS - A new aptamer approach for the recognition of specific small cell lung cancer (SCLC) cell surface molecular markers relies on cell-based systematic evolution of ligands by exponential enrichment (cell-SELEX) to evolve aptamers for whole live cells that express a variety of surface markers representing molecular differences among cancer cells. When applied to different lung cancer cells including those from patient samples, these aptamers bind to SCLC cells with high affinity and specificity in different assay formats. When conjugated with magnetic and fluorescent nanoparticles, the aptamer nano-conjugates could effectively extract SCLC cells from mixed cell media for isolation, enrichment, and sensitive detection. | 09-24-2009 |
Hung-Han Chen, Jacksonville, FL US
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20110055131 | METHOD OF UNIVERSAL COMPUTING DEVICE - A method for using artificial neural networks as a universal computing device to model the relationship between the training inputs and corresponding outputs and to solve all problems with estimation, classification, and ranking tasks in their nature. Raw data related to problems is obtained and a subset of that data is processed and distilled for application to this universal computing device. The training data includes inputs and their corresponding results, which values could be continuous, categorical, or binary. The goal of this universal computing device is to solve problems by the universal approximation property of artificial neural networks. In this invention, a practical solution is created to resolve the issues of local minima and generalization, which have been the obstacles to the use of artificial neural networks for decades. This universal computing device uses an efficient and effective search algorithm, Retreat and Turn, to escape local minima and approach the best solutions. Generalization for this universal computing device is achieved by monitoring its non-saturated hidden neurons as related its effective free parameters and In-line Cross Validation process. The output process of ranking is achieved by an added baseline probability retaining from best logistic regression model as a secondary order while the categorical results from a MLP neural network as the first order. | 03-03-2011 |
James J. Chen, Miami Gardens, FL US
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20150248529 | HEALTHCARE MANAGEMENT SYSTEM - Systems, methods, and computer-readable media for managing and facilitating the delivery of healthcare services are described. Some embodiments provide a healthcare management system configured to analyze and process healthcare information and healthcare expenditure information. Healthcare information may generally include medical information associated with a healthcare entity, such as a patient, a healthcare professional, a healthcare facility, or the like. Healthcare expenditure information may generally include any information associated with the cost of medical care related to a patient, healthcare professional, a healthcare facility, and/or a medical procedure. The healthcare management system may be configured to generate healthcare assessments based on the healthcare information and/or healthcare expenditure information. In general, a healthcare assessment may include any valuation, estimation, ranking, or the like that may indicate the efficiency of an element of healthcare information and/or a healthcare expenditure information, such as the cost efficiency of a medical claim. | 09-03-2015 |
20160063211 | SYSTEMS AND METHODS FOR MODELING MEDICAL CONDITION INFORMATION - Methods, systems, and computer-readable media for presenting graphical user interface objects for generating and/or facilitating resource assessments within a healthcare environment are described. In general, a resource assessment may include a determination of performance of a healthcare unit with respect to healthcare information, for instance, the treatment of a chronic condition. Systems described according to some embodiments may include healthcare assessment models configured to provide visual, graphical tools for automatically generating and/or facilitating the generation of medical and/or resource assessments and/or decisions within a healthcare environment. The models may provide healthcare professionals and administrators with increased visibility into all of the medical diagnoses reported on patients, both from internal and external sources, and the overall process from diagnosing conditions to billing. | 03-03-2016 |
Jianjun Chen, Apopka, FL US
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20110265232 | Aglaonema plant named 'UF-808-4' - A new and distinct variety of | 10-27-2011 |
Jikai Chen, Gainesville, FL US
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20120206281 | SELF-HEALING ANALOG-TO-DIGITAL CONVERTERS WITH BACKGROUND CALIBRATION - Calibration of an analog-to-digital converter (ADC) is accomplished via a reference comparator, a first and second multiplexer (MUX), and a finite state machine (FSM). By sampling an analog input with the reference comparator and comparing the results with those of the ADC using the FSM, all the comparators in the ADC can be calibrated without interrupting the ADC's normal operation. The first MUX provides a same reference voltage to the reference comparator as a comparator selected for the calibration, and the second MUX provides the FSM with the output of the selected comparator. The FSM then performs a comparison of the reference comparator and the selected comparator, extracts the polarity of the mismatch, and updates the contents of a memory with the extracted polarity. An offset control in the selected comparator receives a signal corresponding to the extracted polarity stored in the memory and injects offset current into the comparator. | 08-16-2012 |
Jiun-Jeng Chen, Gainesville, FL US
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20110311769 | ANTIFOULING SURFACES, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME - Disclosed herein is an article comprising a substrate; a polymer disposed upon the substrate; the polymer having a number average molecular weight of about 2,000 to about 5,000 grams per mole; where each polymer is separated from a neighboring polymer by an average distance of 2.5 Angstroms to 5,000 Angstroms. Disclosed herein is a method comprising disposing upon a substrate a polymer; the polymer having a number average molecular weight of 2,000 to about 5,000 grams per mole. | 12-22-2011 |
Junrong Chen, Jacksonville, FL US
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20160111017 | VIRTUAL MIRROR SYSTEMS AND METHODS FOR REMOTELY TRAINING AND/OR SUPPORTING CONTACT LENS USERS - Systems and methods are provided to assist a user with contact lens usage. The system includes a virtualization apparatus on a communication device for use by the contact lens user. The virtualization apparatus includes a front mirror with optical sensor and a side mirror in reflective communication with another optical sensor. The mirrors reflect images of the contact lens user during a contact lens training and support session and the user communication device communicates with a remote trainer or compliance monitor. The method is directed to a trainer or compliance monitor remotely training or monitoring a contact lens user utilizing the systems in accordance with the principles of the invention. | 04-21-2016 |
Kan-Sheng Chen, Tallahassee, FL US
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20130149787 | Devices and Methods for Detection of Biomolecular Interactions - Devices, systems, and methods are provided for the detection of biomolecular interactions. The interactions between one or more target DNA strands, one or more receptor DNA strands, and one or more probe DNA strands, if necessary, are used to detect the one or more target DNA strands. The one or more target DNA strands or the one or more probe DNA strands may be coupled to a magnetic bead, and the one or more receptor strands may be coupled to the Hall device. | 06-13-2013 |
Kezheng Chen, Orlando, FL US
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20090060992 | Preparation of magneto-vesicles with DOPE/DDAB layers - Magneto-vesicles with two different surfactants, i.e., Dioleoyl phosphatidylethanolamine (DOPE) and dimethyl dioctadecylammonium bromide (DDAB), were synthesized using size controllable magnetite nanoparticles (D | 03-05-2009 |
Ling Chen, Gainesville, FL US
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20160102321 | HAIRPIN mRNA ELEMENTS AND METHODS FOR THE REGULATION OF PROTEIN TRANSLATION - The present invention provides novel mRNA elements capable of forming hairpin, double-stranded RNA structures independent of other non-coding RNAs. These mRNAs are stably expressed, lack polyadenylation tails, and allow minimal protein translation except when in the presence of specific proteins. Also provided, are compositions and kits comprising the mRNA element, as well as methods for its use in the regulation of protein translation. Advantageously, the disclosed elements represent a novel tool useful in regulating the expression of a wide variety of proteins of interest. | 04-14-2016 |
Ning Chen, Tampa, FL US
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20130059015 | Human Cancer micro-RNA Expression Profiles Predictive of Chemo-Response - Disclosed are identified and successfully targeted microRNAs (miRNAs) associated with human cancer cell line response to a range of anti-cancer agents. The strategy of integrating in vitro miRNA expression and drug sensitivity data not only aid in the characterization of determinants of cytotoxic response, but also in the identification of novel therapeutic targets. | 03-07-2013 |
Ou Chen, Gainesville, FL US
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20090084307 | One-Pot Synthesis of High-Quality Metal Chalcogenide Nanocrystals Without Precursor Injection - A method of forming monodisperse metal chalcogenide nanocrystals without precursor injection, comprising the steps of: combining a metal source, a chalcogen oxide or a chalcogen oxide equivalent, and a fluid comprising a reducing agent in a reaction pot at a first temperature to form a liquid comprising assembly; increasing the temperature of the assembly to a sufficient-temperature to initiate nucleation to form a plurality of metal chalcogenide nanocrystals; and growing the plurality of metal chalcogenide nanocrystals without injection of either the metal source or the chalcogen oxide at a temperature equal to or greater than the sufficient-temperature, wherein crystal growth proceeds substantially without nucleation to form a plurality of monodisperse metal chalcogenide nanocrystals. Well controlled monodispersed CdSe nanocrystals of various sizes can be prepared by choice of the metal source and solvent system. | 04-02-2009 |
20100264334 | EXCITATION-INTENSITY-DEPENDENT, COLOR-TUNABLE, DUAL EMITTING NANOCRYSTALS - An embodiment of the invention is a device for photo-stimulated color emission having at least one plurally doped semiconducting nanoparticle comprising at least one semiconducting material and a plurality of at least one dopant coupled with an irradiation source such that the plurally doped semiconducting nanoparticle emit electromagnetic radiation at two or more wavelengths where the intensities of the emissions depend on the intensity of the irradiation. In an embodiment of the invention, the plurally doped semiconducting nanoparticle can be a doped core/shell nanoparticle where the plurality of dopants can reside in exclusively the core, exclusively the shell, or in both the core and shell. | 10-21-2010 |
20110031430 | SYNTHESIS OF WATER-SOLUBLE ORGANIC NANOPARTICLES AS EPR STANDARD - Novel water soluble paramagnetic organic nanoparticles are formed by a novel method where an organic solution of an organic compound is injected into water under agitation that is maintained for a desired period of time for nanoparticle growth followed by termination of the growth by the addition of an aqueous surfactant solution. The size of the nanoparticles depends on the time between injection and addition of the surfactant solution. In embodiments of the invention, the water soluble paramagnetic organic nanoparticles can be DPPH nanoparticles, DPPH nanoparticles doped with DPPH-H, or core/shell nanoparticles where a DPPH core is covered by a DPPH-H shell. | 02-10-2011 |
Po Ching Chen, Maitland, FL US
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20140303486 | Surgical Navigation Planning System and Associated Methods - The present disclosure provides a surgical planning and navigation system imports multiple medical imaging sources of the same body part for integrated display in the same coordinate. Images are converted into 3D volumes, spatially co-registering each image volume to a base anatomical image. | 10-09-2014 |
Qin Chen, Gainesville, FL US
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20110320953 | METHOD AND APPARATUS FOR PROJECTING A USER INTERFACE VIA PARTITION STREAMING - Various methods for projecting a user interface via multiple encoded streams are provided. One example method includes generating first and at least second data streams. The data included in the first and second data streams may be configured to cause respective partitions of a unified user interface image to be displayed. The example method may also include generating fiducial information indicating at least a location for displaying the data of the first data streams on a display. The example method may also include causing the first data stream, the second data stream, and the fiducial information to be transmitted from an apparatus to a remote environment for displaying the first partition of the unified user interface image and the second partition of the unified user interface image on a display of the remote environment. Similar and related example methods and example apparatuses are also provided. | 12-29-2011 |
Quanfang Chen, Orlando, FL US
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20100122910 | ELECTROCHEMICAL-CODEPOSITION METHODS FOR FORMING CARBON NANOTUBE REINFORCED METAL COMPOSITES - An electrochemical-codeposition method for forming a carbon nanotube (CNT) reinforced metal nanocomposite includes providing a reaction vessel having an anode and a cathode and a plating solution therein, where the plating solution includes at least one acid, at least one surfactant, a plurality of CNTs, and a plurality of metal cations that include at least one metal. The plating solution has a pH between 2 and 4.5 and at least a portion of the plurality of CNTs are positively charged CNTs in the plating solution. A power supply is connected between the anode and cathode. The positively charged CNTs and metal cations are both electrochemically-codeposited onto the cathode to form the nanocomposite, wherein the metal provides a continuous metal phase for the nanocomposite. | 05-20-2010 |
Ren-Shiang Chen, Miami, FL US
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20090325887 | PEPTIDES AND REGULATION OF CALCIUM CHANNELS - Calcium channels can be regulated by natural gamma proteins. Herein we disclose embodiments of compositions and methods, particularly involving short peptides which are capable of regulating calcium channel function. Certain short peptides which can inhibit calcium current have structural features from the first transmembrane domain of gamma6 such as a GxxxA motif and adjoining aliphatic residues. In embodiments the peptide compositions and methods are capable of selective efficacy for low voltage-activated calcium channels, such as LVA channel Cav3.1, versus high voltage-activated channels. | 12-31-2009 |
Shigang Chen, Gainesville, FL US
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20110289295 | SYSTEM, METHOD, AND MEDIA FOR NETWORK TRAFFIC MEASUREMENT ON HIGH-SPEED ROUTERS - A data structure is provided for storing network contact information based on an array of physical memory locations. Virtual vectors are constructed for each source, wherein each element in each virtual vector is assigned to a corresponding physical memory location within the array. The physical memory locations are shared between the virtual vectors uniformly at random so that the noise introduced by sharing can be predicted and removed. A method for storing network contact information is also provided in which a hash function is performed using the address of a source host to find a virtual vector for holding information about the source host. A second hash function is performed using the address of a destination host to find a virtual memory location, within the virtual vector, for holding information about the destination host. Finally, information is stored at a physical memory location assigned to the virtual memory location. Estimation range enhancement is further provided by performing multiple estimations with different sampling probabilities and selecting a best estimation based on a maximum likelihood method. | 11-24-2011 |
Song Chen, Gainesville, FL US
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20130019937 | PHOTOVOLTAIC CELL ENHANCEMENT THROUGH UVO TREATMENT - Photovoltaic cells, methods of fabricating photovoltaic cells, and methods of using photovoltaic cells to capture light energy are provided. A photovoltaic cell can include an electron transporting layer, a photoactive layer, and a hole transporting layer. The electron transporting layer can be ultraviolet ozone treated. The photovoltaic cell can have an inverted configuration. | 01-24-2013 |
Szu-Yu Chen, Miami, FL US
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20130251684 | METHODS OF ISOLATING AND CULTURING STEM CELLS - Provided herein are methods of isolating and expanding a plurality of multipotent stem cells. Also described are methods of expanding stem cells on a substrate comprising an HC-HA complex. Also described are isolated and expanded stem cells produced by the methods and uses thereof, including stem cell therapy, as niche cells for supporting other types of stem cells, or as bioreactors for the production of HC-HA complexes. Also described are uses of HC-HA complexes as a carrier for stem cells. | 09-26-2013 |
20140106448 | METHODS OF ISOLATING CELLS - Provided herein are methods of isolating and expanding a plurality of multipotent cells (e.g., MSCs and ASCs) using a first culture in a suitable 2-dimensional substrate and a second culture in a suitable 3-dimensional substrate containing the basement membrane component and ROCK inhibitors. Also described are multipotent cell cultures made by the methods. Multipotent cell cultures as described may be used for transplantation or as niche cells for supporting other types of stem cells. | 04-17-2014 |
20150203814 | METHODS OF ISOLATING AND CULTURING STEM CELLS - Provided herein are methods of isolating and expanding a plurality of multipotent stem cells. Also described are methods of expanding stem cells on a substrate comprising an HC-HA complex. Also described are isolated and expanded stem cells produced by the methods and uses thereof, including stem cell therapy, as niche cells for supporting other types of stem cells, or as bioreactors for the production of HC-HA complexes. Also described are uses of HC-HA complexes as a carrier for stem cells. | 07-23-2015 |
Thomas L. Chen, Seminole, FL US
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20140245449 | SYSTEM, METHOD, AND SOFTWARE FOR CYBER THREAT ANALYSIS - According to certain embodiments, a cyber threat analysis system generates a network model of a network infrastructure that is used by an organization, assigns a weighting value to each of a plurality of network elements of the network infrastructure according to a relative importance of the each network element to the organization, and generates an attack vector according to a determined vulnerability of the network infrastructure. The attack vector represents one or more illicit actions that may be performed to compromise the network infrastructure. The system may simulate, using a network modeling tool, the attack vector on the network model to determine one or more resulting ramifications of one or more of the plurality of network elements due to the attack vector, and determine a criticality level of the attack vector according to the weighting value of the one or more network elements. | 08-28-2014 |
Xudong Chen, Orlando, FL US
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20100055299 | DISPENSING PATTERNS INCLUDING LINES AND DOTS AT HIGH SPEEDS - A method for depositing a material on a substrate includes providing an apparatus with at least one material dispenser. The method further includes positioning the pen tip at a predetermined writing gap where the predetermined writing gap is a distance of more than 75 micrometers above the substrate. The method also provides for controlling velocity of the flow of material through the outlet and dispense speed based on dispensed line height and dispensed line width parameters. An apparatus for depositing a material on a substrate is also provided which may have one or more mechanical vibrators, a pen tip with a hydrophobic surface, or multiple nozzles and pen tips on a single pump. | 03-04-2010 |
20130193619 | MICRO-DISPENSING MULTI-LAYERED 3D OBJECTS WITH CURING STEPS - A method of building a three dimensional (3D) structure includes micro-dispensing a layer comprising a material using a syringe-based micro-dispensing tool, curing the layer, and repeating the steps of micro-dispensing and curing a plurality of times in order to build the three-dimensional structure. The material may be loaded with nano to micron sized particles, tubes, or strings. | 08-01-2013 |
20160031159 | METHOD AND APPARATUS FOR 3D FABRICATION - An apparatus for use in 3D fabrication includes a heat sink, a melt tube extending through the heat sink, the melt tube having a first end and an opposite second end and adapted for melting filament or other material as the material is conveyed from the first end to the second end, a pen tip having an opening therein for ejecting melted material, the pen tip at the second end of the melt tube, and a pen tip holder for securely holding the pen tip during printing, the pen tip holder having a heater element associated therewith. | 02-04-2016 |
Xujie Chen, Tallahassee, FL US
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20150125763 | METAL-AIR FLOW BATTERIES USING OXYGEN ENRICHED ELECTROLYTE - A metal air flow battery includes an electrochemical reaction unit and an oxygen exchange unit. The electrochemical reaction unit includes an anode electrode, a cathode electrode, and an ionic conductive membrane between the anode and the cathode, an anode electrolyte, and a cathode electrolyte. The oxygen exchange unit contacts the cathode electrolyte with oxygen separate from the electrochemical reaction unit. At least one pump is provided for pumping cathode electrolyte between the electrochemical reaction unit and the oxygen exchange unit. A method for producing an electrical current is also disclosed. | 05-07-2015 |
Yao Chen, Tampa, FL US
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20150087044 | POLYHEDRAL CAGE-CONTAINING MESOPOROUS METAL-ORGANIC FRAMEWORKS AS PLATFORM FOR BIOCATALYSIS, METHODS OF MAKING THESE FRAMEWORKS, AND METHODS OF USING THESE FRAMEWORKS - Embodiments of the present disclosure provide compositions including polyhedral mesoporous metal-organic framework including a biomolecule (e.g., enzyme), methods of making these compositions, methods of use, and the like. | 03-26-2015 |
Yen Ting Chen, Palm Beach Gardens, FL US
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20110038835 | ANILIDES AND ANALOGS AS RHO KINASE INHIBITORS - Compounds useful as Rho kinase inhibitors of formula (I): wherein variable are as defined herein are provided. Methods of treatment of malconditions mediated by Rho kinase, and methods of preparation of the compounds, are also provided. | 02-17-2011 |
20110052562 | BENZIMIDAZOLES AND ANALOGS AS RHO KINASE INHIBITORS - Compounds useful as Rho kinase inhibitors according to formula IA or IB: wherein A, B, D, E, R | 03-03-2011 |
20110150833 | BENZOPYRANS AND ANALOGS AS RHO KINASE INHIBITORS - Compounds useful as Rho kinase inhibitors of formula (1) wherein the variables are as defined herein are provided. Methods of treatment of malconditions mediated by Rho kinase, and methods of preparation of the compounds, are also provided. | 06-23-2011 |
20160052913 | SUBSTITUTED BENZIMIDAZOLES AS NOCICEPTIN RECEPTOR MODULATORS - The invention provides modulators of the nociceptin receptor (NOP), including both agonists and antagonists. A compound of the invention can be a selective modulator of NOP with respect to the μ- and κ-opioid receptors (MOP and KOP), thus providing a therapeutic method for the treatment of conditions wherein selective NOP modulation is medically indicated and MOP or KOP modulation may be less desirable. A compound of the invention can be a NOP full agonist, partial agonist, inverse agonist, positive or negative allosteric modulator, or a functionally biased agonist. A compound of the invention can be used for the treatment of an anxiety state, post-traumatic stress disorder, addictive disorders (including overuse of alcohol, tobacco, and drugs of abuse such as cocaine, amphetamines, and opitates), misregulated food intake and/or energy expenditure, cough, sleep disorders, grain, pain, depression, or neurodegenerative disorders such as Parkinsons disease or Alzheimers disease. | 02-25-2016 |
Yuan Chen, Orlando, FL US
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20160026037 | Display with Reduced Color Mixing - A display may have a thin-film transistor layer formed from a layer of thin-film transistor circuitry on a substrate, a color filter layer, and a layer of liquid crystal material interposed between the thin-film transistor layer and the color filter layer. The thin-film transistor layer, the liquid crystal layer, and the color filter layer may be sandwiched between upper and lower polarizers. A backlight unit may supply backlight illumination for pixels in the display. The color filter layer may have a black matrix with an array of openings. Color filter elements of different colors may be formed in the openings. The black matrix may have sidewalls that are steep or that are undercut. The profile of the black matrix helps block improperly colored off-axis light and thereby reduces undesired color mixing in the display. | 01-28-2016 |
Yuansha Chen, Gainesville, FL US
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20110086059 | NON-HEMOLYTIC CLYA FOR EXCRETION OF PROTEINS - The disclosure below provides a protein export system utilizing non-hemolytic variants of HlyE family member proteins for efficiently producing recombinant protein from a host cell. In a preferred embodiment, the protein export system utilizes protein export machinery endogenous to the host bacterium into which the protein export system vector is introduced. | 04-14-2011 |
Yu-Min Chen, Gainesville, FL US
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20150097589 | CORROSION DETECTION IN STRUCTURAL TENDONS - Various examples are provided for corrosion detection in structural tendons. In one example, among others, a method includes injecting current through a portion of a tendon assembly including a tendon at least partially encased in grout, where the current is injected through the portion of the tendon assembly via contact points on a surface of the grout. A potential across the portion of the grout surface is measured and a condition of the tendon can be based at least in part upon the current and the potential. In another example, a system includes supply electrodes to inject current into grout surrounding a tendon via contact with a surface of the grout, sensor electrodes to measure a potential difference between the supply electrodes, and an impedance detection device to determine an impedance of the tendon based at least in part upon the injected current and the potential difference. | 04-09-2015 |
Yung T. Chen, Davenport, FL US
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20100147361 | Tandem junction photovoltaic device comprising copper indium gallium di-selenide bottom cell - Embodiments of a monolithic tandem junction solar cell are described that include a CIGS bottom cell and top cell forming an n-i-p diode comprising n-type, i-type and p-type layers of a μc-SiCGe:H with approximate E | 06-17-2010 |
20100300505 | Multiple junction photovolatic devices and process for making the same - A photovoltaic device having multiple photoelectric conversion cells disposed in a tandem configuration and a chemical vapor deposition method for fabricating the same are disclosed. Each photoelectric conversion cell has a different band gap energy and includes a p-type semiconductor layer, an intrinsic semiconductor layer and an n-type semiconductor layer in sequential touching contact. Each semiconductor layer is formed of a nano-crystalline semiconductor containing silicon as a principal constituent. The semiconductor layer may be deposited by a novel chemical vapor deposition method which utilizes plasma and laser energies simultaneously to decompose a film forming gas, thereby forming a semiconductor film on a substrate. The chemical vapor deposition process may be carried out on a continuously conveying substrate, thereby permitting high throughput production of the photovoltaic device. | 12-02-2010 |
Yunmei Chen, Gainesville, FL US
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20140219535 | Systems and Methods for Detecting the Presence of Anomalous Material within Tissue - In one embodiment, the presence of anomalous material within tissue is detected by scanning a patient using magnetic resonance imaging (MRI) to obtain MRI data, identifying individual voxels of the MRI data, identifying multiple parameters of each voxel, and determining as to each voxel based upon the identified parameters the likelihood of tissue represented by the voxel containing anomalous material. | 08-07-2014 |
Yushan Chen, Orlando, FL US
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20090099824 | Distributed Physics Based Training System and Methods - A distributed simulation system is composed of simulator stations linked over a network that each renders real-time video imagery for its user from scene data stored in its data storage. The simulation stations are each connected with a physics farm that manages the virtual objects in the shared virtual environment based on their physical attribute data using physics engines, including an engine at each simulation station. The physics engines of the physics farm are assigned virtual objects so as to reduce the effects of latency, to ensure fair fight requirements of the system, and, where the simulation is of a vehicle, to accurately model the ownship of the user at the station. A synchronizer system is also provided that allows for action of simulated entities relying on localized closed loop controls to cause the entities to meet specific goal points at specified system time points. | 04-16-2009 |
20120007869 | Distributed physics based training system and methods - A distributed simulation system is composed of simulator stations linked over a network that each renders real-time video imagery for its user from scene data stored in its data storage. The simulation stations are each connected with a physics farm that manages the virtual objects in the shared virtual environment based on their physical attribute data using physics engines, including an engine at each simulation station. The physics engines of the physics farm are assigned virtual objects so as to reduce the effects of latency, to ensure fair fight requirements of the system, and, where the simulation is of a vehicle, to accurately model the ownship of the user at the station. A synchronizer system is also provided that allows for action of simulated entities relying on localized closed loop controls to cause the entities to meet specific goal points at specified system time points. | 01-12-2012 |
Zhifeng Chen, Gainesville, FL US
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20100098162 | System and Method for Bit-Allocation in Video Coding - A system and method for region-of-interest-based bit-allocation scheme for video coding is provided. A method for encoding an image sequence of inter-frames and intra-frames includes grouping the inter-frames and the intra-frames in at least one group of pictures (GOP), and performing a frame-level bit-allocation to inter-frames and the intra-frames in the GOP. For each frame of the inter-frames and the intra-frames in the GOP, the method also includes partitioning the frame into a plurality of macroblocks, identifying macroblocks in the plurality of macroblocks as having regions of interest (ROI), and performing a macroblock level bit-allocation for the frame based on macroblocks identified as having ROI. The method further includes encoding the image sequence based on the bit-allocations, thereby producing an encoded image sequence, and outputting the encoded image sequence. | 04-22-2010 |
Zhihong Chen, Gainesville, FL US
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20100272981 | TRANSPARENT AND ELECTRICALLY CONDUCTIVE SINGLE WALL CARBON NANOTUBE FILMS - An optically transparent and electrically conductive single walled carbon nanotube (SWNT) film comprises a plurality of interpenetrated single walled carbon nanotubes, wherein for a 100 nm film the film has sufficient interpenetration to provide a 25° C. sheet resistance of less than 200 ohm/sq. The film also provides at least 20% optical transmission throughout a wavelength range from 0.4 μm to 5 μm. | 10-28-2010 |