Krah
Daniel L. Krah, Landsdale, PA US
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20110212130 | LIVE, ATTENUATED RESPIRATORY SYNCYTIAL VIRUS - The present invention features live, attenuated respiratory syncytial viruses (RSV) useful as vaccines against RSV infection and/or the development of severe RSV-associated illnesses. The disclosed viruses are attenuated to the extent of being nonpathogenic when administered to a subject but substantially retain the antigenic and immunogenic properties of wild-type RSV. | 09-01-2011 |
David Krah, Lansdale, PA US
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20140294872 | METHODS OF PREPARING LYOPHILIZED SPHERICAL-SHAPED PELLETS OF BIOLOGICAL MATERIALS - Methods for preparing lyophilized pellets of biological materials are described. The pellets have a substantially spherical shape and are prepared by freezing droplets of a liquid composition of a desired biological material on a flat, solid surface, in particular, a surface that does not have any cavities, followed by lyophilizing the frozen droplets. These methods are useful for preparing lyophilized pellets having a high concentration of a desired biological material, in particular a therapeutic protein or vaccine, and which have a faster reconstitution time than lyophilized powder cakes prepared in vials. | 10-02-2014 |
David L. Krah, Lansdale, PA US
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20120034267 | INACTIVATED VARICELLA ZOSTER VIRUS VACCINES, METHODS OF PRODUCTION, AND USES THEREOF - The invention provides an inactivated varicella zoster virus (VZV), and compositions and vaccines comprising said inactivated VZV, wherein the infectivity of the VZV is undetectable and wherein the inactivated VZV induces an immune response against VZV when administered to a patient. In embodiments of the compositions described herein, the VZV is inactivated with gamma radiation. The invention also provides a method of preparing an inactivated VZV vaccine, the method comprising gamma irradiating a sample comprising a VZV using from about 5 kGy to about 50 kGy of gamma radiation. Also provided by the invention herein is a method of treatment of or immunization against HZ or other disease associated with the reactivation of VZV, the method comprising administering to a subject a vaccine or pharmaceutical composition comprising a therapeutically effective amount of an inactivated VZV and a pharmaceutically acceptable carrier, wherein the VZV is inactivated by gamma irradiation. | 02-09-2012 |
Drew Allen Krah, Vashon, WA US
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20090104828 | Human powered watercraft - Human powered watercrafts, propulsion devices, and methods of propulsion are provided. A watercraft having an upper deck is configured with a cam plate having a pedal above the deck and a plate and cam below the deck, the cam engaging a cam follower of a fin bar, the fin bar having a substantially vertical propelling fin at an aft end and a pivot to the craft at a forward end. In another embodiment the craft receives two cam plates with pedals, a plurality of fin bars and two propelling fins, all operatively interconnected by a pulley and belt such that a leg thrust upon a pedal opens the fins and an opposite leg thrust upon the opposing pedal closes the fms. Another embodiment, an open, hollow surfboard receives the propulsion device and a buoyancy compensator making a submersible human powered watercraft which may be propelled upon and beneath the sea. | 04-23-2009 |
Eugene Regis Krah, Freeport, ME US
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20080227194 | Canine pancreatic lipase - Isolated nucleic acid molecules having a nucleotide sequence encoding canine pancreatic lipase polypeptides, allelic variants and fragments thereof. Vectors and host cells containing the polynucleotide sequences and methods for expressing the polypeptides. Monoclonal antibodies that specifically binds to the canine pancreatic lipase polypeptides. Cell lines secreting the monoclonal antibodies. Methods for determining the presence or amount of canine pancreatic lipase in a biological sample. The methods include using the monoclonal antibodies to specifically bind to canine pancreatic lipase polypeptides. The method includes using standards of recombinant canine pancreatic lipase. Devices and kits for performing methods for detecting canine pancreatic lipase in biological samples. | 09-18-2008 |
20090098576 | Feline Pancreatic Lipase - Isolated nucleic acid molecules having a nucleotide sequence encoding feline pancreatic lipase polypeptides, splice variants, allelic variants, and fragments thereof. Isolated feline pancreatic lipase polypeptides, splice variants, allelic variants, and fragments thereof. Host cells comprising a vector containing the polynucleotide sequences and methods for expressing the polypeptides. The generation of monoclonal antibodies that specifically binds to the feline pancreatic lipase polypeptides, and cell lines secreting the monoclonal antibodies. Methods for determining the presence or amount of feline pancreatic lipase in a biological sample. The methods include using standards or calibrators of recombinant feline pancreatic lipase to quantify the lipase in a sample. Devices and kits for performing methods for detecting feline pancreatic lipase in biological samples. | 04-16-2009 |
Eugene Regis Krah, Yarmouth, ME US
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20130101987 | Detection of feline Immunodeficiency Virus - Method, device and kit for the detection of antibodies directed to Feline Immunodeficiency Virus (FIV). The method includes contacting the felid biological sample with FIV env polypeptide and detecting whether the polypeptide substantially binds to the antibody in the biological sample. The method will detect FIV antibodies in a sample from animals that have been naturally infected but the method will not detect antibodies in a sample from animals that have not been infected and that have not been vaccinated with an FIV vaccine after within about the previous five to eight weeks. | 04-25-2013 |
Gert Krah, Hattert DE
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20140213121 | Modular Electrical Connector Assembly and Associated Method of Making - A method for producing modular electrical connectors having varying contact element configurations includes providing a common header component having a plurality of receptacle spaces defined therein. A plurality of different contact sub-assemblies are provided having varying contact element configurations, with each of sub-assembly having a common size configured for receipt in the receptacle spaces. A pattern of the contact sub-assemblies is defined for a particular desired connector configuration from any combination of the contact sub-assemblies, and the contact sub-assemblies are fitted and adhered into the receptacle spaces in the header component according to the pattern. A kit may be provided with the modular components for making the connectors. | 07-31-2014 |
Holgar Krah, West Bloomfield, MI US
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20090299529 | EFFICIENT AC OPERATION USING DEW-POINT TEMPERATURE - A system for controlling air-conditioning in a vehicle includes an input, a sensor, a first offset module, and an evaporator temperature control module. The input receives an input temperature. The first sensor measures a first dewpoint temperature of air adjacent to a windshield of the vehicle. The first offset module generates a second dewpoint temperature based on the input temperature and generates a first offset based on the first and second dewpoint temperatures. The evaporator temperature control module generates a target evaporator temperature based on the first offset. | 12-03-2009 |
Jens Onno Krah, Wuppertal DE
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20100141198 | CLOSED-LOOP CONTROL METHOD AND CLOSED-LOOP CONTROL DEVICE WITH MULTI-CHANNEL FEEDBACK - A method of closed-loop controlling determines a first feedback variable by sampling a control variable and a second feedback variable by averaging the control variable, compares the first and second feedback variables with a command variable, and sets the control variable on the basis of the comparing result so that the control variable follows a command variable. | 06-10-2010 |
20120299522 | TWO-QUADRANT CHOPPER - A two-quadrant chopper including a first node, a second node, a third node and a fourth node wherein an input voltage may be applied between the first node and the second node, a first output voltage may be picked off between the first node and the third node and a second output voltage may be picked off between the third node and the second node. A first capacitor is between the first node and the third node and a second capacitor is between the third node and the second node. A collector of a first transistor is connected to the first node and an emitter of the first transistor is connected to the fourth node. A cathode of a first diode is connected to the first node and an anode of the first diode is connected to the fourth node. A collector of the second transistor is connected to the fourth node and an emitter of the second transistor is connected to the second node. A cathode of a second diode is connected to the fourth node and an anode of the second diode is connected to the second node. An inductor is arranged between the third node and the fourth node. | 11-29-2012 |
20140355318 | FEED-IN/FEEDBACK CONVERTER - A method of controlling a frequency converter comprises steps for measuring phase currents flowing in a three-phase supply network, for generating a first modulation space vector that comprises an angle that is synchronous to a supply voltage of the three-phase supply network and a determined modulation index as an amplitude, for generating a third modulation space vector depending on the first modulation space vector and the measured phase currents and for modulating the frequency converter according to the third modulation space vector. | 12-04-2014 |