Tzong-Yuan Wu
Tzong-Yuan Wu, Panchiao City TW
Patent application number | Description | Published |
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20080241922 | Use of Biocistronic DNA Constructs for Identifying Compounds that Inhibit IRES-Dependent Translation - The present invention relates to use of bicistronic DNA constructs for identifying compounds that inhibits IRES-dependent translation activity of an infectious enterovirus (EV) or encephalomyocarditis virus (EMCV) without affecting CAP-dependent translation activity of a host subject. The compounds thus identified are useful in preparation of a medicament for treating EV or EMCV infection. | 10-02-2008 |
20080242734 | Use of Biocistronic DNA Constructs for Identifying Compounds that Inhibit IRES-Dependent Translation - The present invention relates to use of bicistronic DNA constructs for identifying compounds that inhibits IRES-dependent translation activity of an infectious enterovirus (EV) or encephalomyocarditis virus (EMCV) without affecting CAP-dependent translation activity of a host subject. The compounds thus identified are useful in preparation of a medicament for treating EV or EMCV infection. | 10-02-2008 |
20100209910 | Methods and systems for identifying polynucleotide sequences with translational self-cleavage activity - Provided herein are methods and systems for identifying 2A-like sequences with translational self-cleavage activity in an insect expression system. | 08-19-2010 |
20100223683 | Isolated Polynucleotide Sequence with IRES Activity - Provided herein is an isolated polynucleotide sequence with internal ribosome entry site (IRES) activity, which directs translation initiation in an insect expression system in a cap-independent manner. In particular, the invention relates to an isolated polynucleotide comprises the 5′ UTR of | 09-02-2010 |
20120231536 | CHIMERAL INTERNAL RIBOSOMAL ENTRY SITE SEQUENCE AND USES THEREOF - An improved baculovirus vector capable of expressing genes in mammalian or insect host cells, and the uses thereof are disclosed. The improved baculovirus vector includes in sequence: a promoter; a first nucleic acid operably linked to the promoter for expressing a first protein in the mammalian or insect host cells; a chimera internal ribosomal entry site (IRES) comprising a portion of an enterovirus (EV) IRES sequence at least 90% identical to SEQ ID NO: 1 and a portion of a | 09-13-2012 |
20150252332 | HYBRID BACULOVIRUS AND USES THEREOF - Disclosed herein is an | 09-10-2015 |
20150252333 | HYBRID BACULOVIRUS HAVING THE CAPABILITY OF INFECTING AT LEAST THREE INSECT HOSTS AND USES THEREOF - Disclosed herein is an | 09-10-2015 |
Tzong-Yuan Wu, New Taipei City TW
Patent application number | Description | Published |
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20140087372 | PROBE, KIT, AND METHOD FOR DETECTING PATHOGENIC MICROORGANISM - Disclosed herein is a hairpin probe for detecting a target pathogenic microorganism in a sample. The hairpin probe includes a microbead and an oligonucleotide having its 3′-end coupled to the microbead. The oligonucleotide includes, from 5′ to 3′, a Tag sequence hybridizable to a specific identification sequence of the pathogenic microorganism, an internal control sequence having at least four words each having 4 nucleotides with a 75% AT-content, an anti-Tag sequence being a reverse complement of the Tag sequence, and a tail having at least two consecutive thymidine residues. The Tag and anti-Tag sequences are operable to form a stem of the hairpin probe with the internal control sequence being a loop. Also disclosed herein are, a kit including the hairpin probe and a method for using the kit in the detection of a target pathogenic microorganism. | 03-27-2014 |