Helena
Helena Akerud, Uppsala SE
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20130053330 | Fertilization Prediction and Promotion - The outcome of an in vitro fertilization (IVF) of a woman in terms of chances of successful pregnancy or the fertility status of a woman is predicted based on nucleotide analysis of the histidine-rich glycoprotein (HRG) gene or protein analysis of HRG. The proline isoform of HRG or an amino acid fragment thereof can further be used to increases the success of pregnancy of a woman. | 02-28-2013 |
20140127693 | Fertilization Prediction and Promotion - The outcome of an in vitro fertilization (IVF) of a woman in terms of chances of successful pregnancy or the fertility status of a woman is predicted based on nucleotide analysis of the histidine-rich glycoprotein (HRG) gene or protein analysis of HRG. The proline isoform of HRG or an amino acid fragment thereof can further be used to increases the success of pregnancy of a woman. | 05-08-2014 |
Helena Alfonzo, Chestnut Hill, MA US
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20110142804 | NANOFIBER SCAFFOLD - The invention is directed to a device and method to prevent migration of Human Mesenchymal Stem Cells (hMSCs) from a delivery site while allowing communication between the stem cells and native cardiomyocytes. The device is characterized by scaffold pore size, fiber diameter and biomaterial selection. The invention includes a two part polyurethane scaffold that prevents migration of stem cells, allows gap junction formation through pores and is packaged for minimally invasive delivery. | 06-16-2011 |
Helena Andersson, Alingsas SE
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20090123324 | Iron-Base Alloy Containing Chromium-Tungsten Carbide And a Method Of Producing It - A method and cast wear resistant component made of an alloy that includes carbon, tungsten, chromium, and cobalt with the balance essentially iron and other alloying components made using waste, surplus or worn-out cemented carbide product, such as cemented carbide cutting tool inserts. In one method, the alloy further includes silicon, manganese, nickel, titanium, and molybdenum. In practicing the method, pieces of waste, surplus or worn-out cemented carbide product having tungsten carbide (WC) are added to a cast iron alloy melt. The melt includes enough chromium to control solubility of the WC. In one method, precipitated carbide structure having chromium and carbon is produced with tungsten in the melt being substitutionally dissolved. In one implementation, tungsten is substitutionally dissolved in a lattice of the precipitated carbide structure. Carbide can be added to the melt via super inoculation. The cast wear resistant component can be a cutting tool. | 05-14-2009 |
Helena Berndtsson Arvidsson, Goteborg SE
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20130042771 | APPARATUS AND METHOD FOR TREATING PRODUCTS - An apparatus for treating products continuously fed to the apparatus includes a first roller rotatable around a first rotation axis and a second roller rotatable around a second rotation axis parallel to the first rotation axis. A treatment gap is formed between the first roller and the second roller. The apparatus further includes an adjusting means for in-line adjusting the nominal size of the treatment gap. The adjusting means includes at least one piezoelectric element for shifting the position of the first rotation axis and/or the second rotation axis. | 02-21-2013 |
Helena Bilerova, Liberec CZ
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20100260809 | Preparation For Wound Healing And Prevention Of Bandage Adhesion To The Wound, Containing Chitosan-Glucan - The invention relates to a preparation containing a pharmacologically suitable chitosan-glucan complex or a salt thereof, either alone or in combination with one or more polysaccharides or suitable salts thereof and an antiseptic agent, that is intended for wound healing and that, besides accelerating wound healing, is at the same time able to prevent a bandage adhesion to the wound. The preparation according to the invention, having been applied, indirectly supports the healing processes in the wound and drains the redundant secretion together with the tissue mediators and enzymes that support the healing. By doing this, it provides for the necessary hydration of the wound and its surroundings, without any maceration of the surrounding skin or drying and sticking to the wound. An addition of antiseptic agents prevents a further infection. The preparation contains 0.01 to 100% by weight of chitosan-glucan complex, 0 to 99.99% by weight of another polysaccharide and 0 to 50% by weight of an antiseptic agent. | 10-14-2010 |
Helena Camps Ramírez De Cartagena, Rubi ES
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20100204476 | Process for preparing a leukotriene antagonist and an intermediate thereof - Dicyclohexylamine salt of formula (IIa) or a pharmaceutically acceptable solvate thereof, including a hydrate, and its process for preparation are provided. The invention also relates to processes for the preparation of montelukast of formula (I) or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate thereof, including a hydrate, based on the conversion of a salt of formula (IIa) into its form of free acid, followed by reaction with a compound of formula (III) CH3MgX, wherein X is halogen, in a suitable solvent, optionally in the presence of a Lewis acid. | 08-12-2010 |
Helena Camps Ramírez De Cartagena, Rubi ES
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20100204476 | Process for preparing a leukotriene antagonist and an intermediate thereof - Dicyclohexylamine salt of formula (IIa) or a pharmaceutically acceptable solvate thereof, including a hydrate, and its process for preparation are provided. The invention also relates to processes for the preparation of montelukast of formula (I) or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate thereof, including a hydrate, based on the conversion of a salt of formula (IIa) into its form of free acid, followed by reaction with a compound of formula (III) CH3MgX, wherein X is halogen, in a suitable solvent, optionally in the presence of a Lewis acid. | 08-12-2010 |
Helena Catalan-Asenjo, Muenchen DE
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20090218232 | Method for the Pre-Treatment of Titanium Components for the Subsequent Coating Thereof - A method for the pre-treatment of titanium components for the subsequent coating thereof is provided. The method includes at least the following steps: a) etching of the component in an acidic solution containing fluoride and nitric acid (HNO3); b) activation pickling of the etched component in a solution containing at least sodium nitrate (NaNO3) and tetrafluoroboric acid (HBF4); and c) activation of the activation-pickled component in a bath containing acid or in an acidic bath containing nickel. | 09-03-2009 |
Helena Ceric, Zagreb HR
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20090137613 | PHARMACEUTICALLY ACCEPTABLE SALTS AND POLYMORPHIC FORMS - The present invention is concerned with new pharmaceutically acceptable salts of valacyclovir, polymorphic forms, processes for preparing the new pharmaceutically acceptable salts and new polymorphic forms, pharmaceutical compositions containing the same, therapeutic uses thereof and methods of treatment employing the same. | 05-28-2009 |
20110196008 | POLYMORPHS OF ELTROMBOPAG AND ELTROMBOPAG SALTS AND PROCESSES FOR PREPARATION THEREOF - New polymorphs of Eltrombopag and Eltrombopag ethanolamine salt have been obtained and characterized. These polymorphs and pharmaceutical compositions comprising them are useful, for example, in treating conditions leading to thrombocytopenia. | 08-11-2011 |
20120022124 | POLYMORPHS OF ELTROMBOPAG AND ELTROMBOPAG SALTS AND PROCESSES FOR PREPARATION THEREOF - New polymorphs of Eltrombopag and Eltrombopag ethanolamine salt have been obtained and characterized. These polymorphs and pharmaceutical compositions comprising them are useful, for example, in treating conditions leading to thrombocytopenia. | 01-26-2012 |
20120238612 | POLYMORPHS OF ELTROMBOPAG AND ELTROMBOPAG SALTS AND PROCESSES FOR PREPARATION THEREOF - New polymorphs of Eltrombopag and Eltrombopag ethanolamine salt have been obtained and characterized. These polymorphs and pharmaceutical compositions comprising them are useful, for example, in treating conditions leading to thrombocytopenia. | 09-20-2012 |
Helena Cheminet, Gradignan FR
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20090081260 | NATURALLY RESORBABLE POLYACRYLAMIDE GEL, PRODUCTION PROCESS AND USES - A biodegradable polyacrylamide gel that is obtained from acrylamide monomers that are connected to one another by at least one amino acid includes at least one acryloylated amine or acryloylated amide group, or by at least one amino acid oligopeptide that comprises at least one acryloylated amine or acryloylated amide group. The process for synthesis of this gel and its uses are also disclosed. | 03-26-2009 |
20100040571 | POLYMERIC DEPILATORY COMPOSITION WITH CONTROLLED TEMPERATURE SETTING OF USE - The object of the invention is a polymeric depilatory (epilatory) composition including: a. at least one basic compound permitting adherence to the hair, b. at least one wax-based rheology regulating compound, and c. at least one microwave absorber compound. | 02-18-2010 |
Helena Corneliusson, Bohus SE
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20090192483 | INITIAL PRODUCT ADAPTABLE TO SERVE AS A GARMENT AND ITS METHOD OF MANUFACTURING - An initial product ( | 07-30-2009 |
20090204093 | GARMENT FOR USE WITH AN ABSORBENT STRUCTURE AND ITS METHOD OF MANUFACTURE - A garment such as a diaper, training pant, pull-up diaper, adult incontinence pant and diaper holder. The garment includes a chassis for receiving the absorbent structure. The chassis includes a first lateral margin and a second lateral margin. The first and second lateral margins are joined to a central structure along a first line of joinder and a second line of joinder, respectively, the first and second lines of joinder extending substantially parallel to the longitudinal axis. The first and second lateral margins have a first end region, a second end region and a central region. The first and second lateral margins has a material which is elastically extensible in at least the longitudinal direction in the central region and elastically extensible in at least one of the first and second end regions in at least the transverse direction. A method of manufacturing a garment is also disclosed. | 08-13-2009 |
20100137823 | ABSORBENT ARTICLE WITH IMPROVED FIT - An absorbent article includes a chassis extending about a longitudinal axis and having a topsheet, a backsheet and an absorbent structure disposed between the topsheet and the backsheet. The chassis has a first transverse axis dividing the absorbent structure into a front body panel terminating in a front waist region and a rear body panel terminating in a rear waist region. The rear waist region has a first elastic region. The chassis is delimited by opposed longitudinal edges and opposed transverse edges. In the rear waist region, the absorbent structure terminates at a first distance from the transverse edge and the first elastic region extends substantially parallel to the transverse edge and spaced therefrom by a second distance and spaced from the absorbent structure by a third distance. The third distance is greater than said second distance or substantially equal thereto. | 06-03-2010 |
20100170614 | METHOD FOR CUTTING OUT DISCRETE FASTENING ELEMENTS AND APPLYING THESE TO AN ABSORBENT ARTICLE, AND THE ABSORBENT ARTICLE - A method for cutting discrete fastening elements ( | 07-08-2010 |
Helena Corominola Ocana, Barcelona ES
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20080206356 | Pharmaceutical Compositions for the Treatment of Neurodegenerative Disorders - Pharmaceutical compositions comprising an effective amount of a tungsten (VI) compound, preferably of a tungstate salt, and more preferably of sodium tungstate (Na | 08-28-2008 |
Helena Cucak, Malmoe SE
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20140178395 | TREATMENT OF NEPHROPATHY - The present invention relates to treatment of nephropathy. In particular, the present invention relates to treatment of nephropathy using therapeutic antibodies. | 06-26-2014 |
20140178396 | TREATMENT OF CARDIOVASCULAR DISEASES - The present invention relates to treatment of cardiovascular diseases and arthero-sclerosis. In particular, the present invention relates to use of therapeutic antibodies. | 06-26-2014 |
Helena De Voogd-Claessen, Leiden NL
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20080224934 | Tight-Fitting Garment Including a Sensor for Measuring Length and/or Shape - A tight-fitting garment comprising a dipole resonator which is adapted to vary its length and/or shape in conformity with the length and/or shape variations of a person wearing the garment. The length and/or shape of the resonator determines the resonance frequency which can be detected by a reflection analyser. The dipole resonator comprises at least one elastic core around which a conductive wire is wound. The dipole resonator is further suitable to elastically deform along with the tight-fitting garment. | 09-18-2008 |
Helena Esteve Nunez, Barcelona ES
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20130090030 | COATED FIBRES, YARNS AND TEXTILES - A method of treatment for synthetic or natural fibre or yarn includes coating the fibre/yarn with a dispersion of carbon nanotubes in a coating composition which is cured by actinic radiation, such as UV, to provide a flexible conductive layer on the fibre/yarn. The liquid coating composition is sheared along the direction of a long axis of the yarn as it is applied to the yarn whereby the carbon nanotubes are substantially aligned prior to curing of the coating layer to provide improved longitudinal conductance. The method provides conductive fibre/yarn, from which anti-static textiles and fabrics can be formed, by treatment of conventional fibre/yarn and in a method with low energy consumption. The improved conductance allows thin or partial (e.g. stripe) coating layers to be used for yarns which provide good feel and handle, combined with good conductivity, for textiles formed from the yarns Coating compositions for use in the method are disclosed as are anti-static yarns, fibres fabrics and textiles resulting from the method. | 04-11-2013 |
Helena Farnikova, Regensburg DE
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20120035523 | SYSTEM FOR TREATMENT OF BLOOD - The present invention relates to a system for the treatment of blood, in particular a highly efficient system for the safe removal of CO2 and bicarbonates from the blood in a blood circuit connected to a patient by means of a venous-venous connection having at least an inlet or tube line ( | 02-09-2012 |
Helena Gamero-Diaz, Frisco, TX US
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20120239363 | PRODUCTION ESTIMATION IN SUBTERRANEAN FORMATIONS - A system has a tool capable of obtaining data that characterizes a stimulated reservoir or from which the stimulated reservoir can be characterized. The system also includes a processor capable of predicting the production of the stimulated reservoir using the characterizing data and outputting the predicted production. A reservoir may be stimulated using a stimulation process and data may be obtained that characterizes the stimulated reservoir or from which the stimulated reservoir can be characterized. The production of the stimulated reservoir may be predicted using the data. Alternatively, a reservoir may be stimulated using a stimulation process and data that characterizes the stimulated reservoir or from which the stimulated reservoir can be characterized may be obtained. One or more 3-D volumes may be produced based on the characterizing data, and inferences about the stimulated reservoir may be made using the one or more 3-D volumes. | 09-20-2012 |
Helena Gleskova, Princeton, NJ US
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20080303436 | Method for pattern metalization of substrates - A method for forming an adhesion layer in contact with a first surface of a substrate and a surface of a layer having electrically conductive properties using electrophotographic imaging compound as a mask is provided. The adhesion layer improves the lamination properties of the electrically conductive layer to the substrate. The improved lamination properties to facilitate and increase the reliability and quality of a resulting product having an electronic circuit formed in accordance with the present invention. The method disclosed herein is well suited for use with rigid polymeric substrates and flexible polymeric substrates. | 12-11-2008 |
Helena Gonzalez Penas, Lyon FR
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20130090510 | PROCESS FOR DEHYDRATION OF DILUTE ETHANOL INTO ETHYLENE WITH LOW ENERGY CONSUMPTION WITHOUT RECYCLING OF WATER - A process for dehydration of an ethanol feedstock into ethylene, comprising the vaporization of said dilute hydrated ethanol feedstock in an exchanger, with heat exchange with the effluent that is obtained from a last reactor, with said mixture being introduced into said vaporization stage at a pressure that is lower than the pressure of the effluent that is obtained from the last reactor, the compression of the mixture that is vaporized in a compressor, the introduction of the vaporized and compressed mixture, into at least one adiabatic reactor that contains at least one dehydration catalyst. | 04-11-2013 |
20130190547 | PROCESS FOR DEHYDRATION OF ETHANOL INTO ETHYLENE WITH LOW ENERGY CONSUMPTION - A process for dehydration of an ethanol feedstock into ethylene, comprising the vaporization of said ethanol feedstock in a mixture with at least a portion of the recycled purified water stream from heat exchange with the effluent that is obtained from the last reactor. | 07-25-2013 |
Helena Grinberg-Rashi, Raanana IL
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20100145131 | METHODS AND KITS FOR PREDICTING CANCER METASTASIS - A method of predicting CNS metastasis of a non-neuronal cancer in a subject is disclosed. The method comprises determining a level and/or activity of N-cadherin (CDH2), in a sample of the subject wherein an increase in the CDH2 with respect to an unaffected sample is indicative of the CNS metastasis of the non-neural cancer. The method further comprises determining a level and/or activity or kinesin family member C1 (KIFC1) and/or Fetal Alzheimer Antigen (FALZ1) in the sample wherein an increase in KIFC1 and a decrease in FALZ with respect to an unaffected sample is further indicative of the CNS metastasis of the non-neural cancer. The method may be used for selection of a treatment regimen. In addition, kits for prediction CNS metastasis are disclosed. | 06-10-2010 |
Helena Gybäck, Macclesfield GB
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20140329830 | 2-CARBOXAMIDE-4-PIPERAZINYL-BENZOFURAN DERIVATIVE - The present invention relates to a compound of formula (I), and to pharmaceutical compositions containing said compound and to the use of said compound in therapy, for instance in treating cognitive disorders, as well as to intermediates useful in the preparation thereof. | 11-06-2014 |
Helena GybÄck, Sodertalje SE
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20100331341 | 2-CARBOXAMIDE-7-PIPERAZINYL-BENZOFURAN DERIVATIVES 774 - The present invention relates to compounds of formula (I), | 12-30-2010 |
Helena GybÄck, Sodertalje SE
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20080255106 | Novel 2-Phenyl-Imidazo[4,5-B]Pyridine Derivatives as Inhibitors of Glycogen Synthase Kinase for the Treatment of Dementia and Neurodegenerative Disorders - Compounds of formula I | 10-16-2008 |
20090192190 | Benzoic Acid Derivatives that are Modulators or Agonists of GlyR - Compounds of formula I, | 07-30-2009 |
20100331341 | 2-CARBOXAMIDE-7-PIPERAZINYL-BENZOFURAN DERIVATIVES 774 - The present invention relates to compounds of formula (I), | 12-30-2010 |
20130296296 | 2-Carboxamide-7-Piperazinyl-Benzofuran Derivatives - The present invention relates to compounds of formula (I), | 11-07-2013 |
Helena Gylling, Helsinki FI
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20100179113 | STANOL COMPOSITION AND THE USE THEREOF - A stanol composition containing in addition to sitostanol as the main component, also a substantial amount of at least 10% campestanol has been found to effectively lower serum cholesterol levels when incorporated in edible commodities. Upon esterification the composition is especially useful in edible fats and oils and in fat-containing foods. | 07-15-2010 |
20130237506 | STANOL COMPOSITION AND THE USE THEREOF - A stanol composition containing in addition to sitostanol as the main component, also a substantial amount of at least 10% campestanol has been found to effectively lower serum cholesterol levels when incorporated in edible commodities. Upon esterification the composition is especially useful in edible fats and oils and in fat-containing foods. | 09-12-2013 |
Helena Hagelin-Weaver, Gainsville, FL US
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20100147699 | CONCURRENT O2 GENERATION AND CO2 CONTROL FOR ADVANCED LIFE SUPPORT - A device for the concurrent oxygen generation and control of carbon dioxide for life support system involves two stages, where a first stage removes CO | 06-17-2010 |
Helena Johansson, Torslanda SE
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20080210246 | Draping Product with an Adhesive Edge, Incision Film or Tape - The present invention relates to a draping product with an adhesive edge, incision film or tape, provided with a soft, skin friendly adhesive. In accordance with invention, the draping product, the incision film or the tape is leakproof in accordance with the MHC Leakage Test with a groove depth of 50 micrometres. | 09-04-2008 |
Helena Johnansson, Wurzburg DE
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20100141270 | PROCESS AND DEVICE TO MEASURE AT LEAST ONE QUALITATIVE VALUE OF A FIBROUS WEB - A process to measure at least one qualitative measure of a moving fibrous web. The fibrous web being a web of paper or cardboard. The process including the steps of influencing, evaluating and determining. The influencing step includes the influencing of at least one microwave resonator by the fibrous web. The evaluating step including the evaluating of at least one resonance curve of the at least one microwave resonator. The determining step including the determining of at least one quality measure of the fibrous web dependent upon results of the evaluating step. | 06-10-2010 |
Helena Katchman, Givataim IL
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20090324607 | Therapeutic Transplantation Using Developing, Human or Porcine, Renal or Hepatic, Grafts - A method of treating a renal, hepatic or enzyme-deficiency disorder in a subject in need thereof is disclosed. The method is effected by transplanting into the subject tissue derived from a human or porcine, kidney or liver, the kidney or liver being at a selected gestational stage. | 12-31-2009 |
20100021433 | Disease treatment via developing non-syngeneic graft transplantation - A method of providing a pancreatic, lymphoid/hematopietic or pulmonary organ and/or tissue function to a mammalian subject is provided. The method comprises transplanting into the subject a developing mammalian pancreatic, lymphoid/hematopietic or pulmonary organ/tissue graft, respectively, thereby generating a functional pancreatic, lymphoid/hematopietic or pulmonary organ and/or tissue, respectively, for providing the pancreatic, lymphoid/hematopietic or pulmonary organ and/or tissue function, respectively, to the subject. | 01-28-2010 |
20100221270 | THERAPEUTIC TRANSPLANTATION USING DEVELOPING, HUMAN OR PORCINE, RENAL OR HEPATIC, GRAFTS - A method of treating a renal, hepatic or enzyme-deficiency disorder in a subject in need thereof is disclosed. The method is effected by transplanting into the subject tissue derived from a human or porcine, kidney or liver, the kidney or liver being at a selected gestational stage. | 09-02-2010 |
20150010512 | Disease treatment via developing non-syngeneic graft transplantation - A method of providing a pancreatic, lymphoid/hematopietic or pulmonary organ and/or tissue function to a mammalian subject is provided. The method comprises transplanting into the subject a developing mammalian pancreatic, lymphoid/hematopietic or pulmonary organ/tissue graft, respectively, thereby generating a functional pancreatic, lymphoid/hematopietic or pulmonary organ and/or tissue, respectively, for providing the pancreatic, lymphoid/hematopietic or pulmonary organ and/or tissue function, respectively, to the subject. | 01-08-2015 |
Helena Kaukinen, Paimio FI
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20110071203 | TRANSMUCOSAL VETERINARY COMPOSITION COMPRISING DETOMIDINE - The present invention relates to a veterinary composition in a semisolid form adapted for transmucosal administration for providing sedation and analgesia in large animals such as horses and cattle. The semisolid transmucosal composition of the invention comprises detomidine or a pharmaceutically acceptable salt thereof as an active ingredient. The composition provides a rapid onset of action while having low irritation potential in the oral mucosa. | 03-24-2011 |
Helena Kaylin, Huntington, NY US
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20130225042 | Garment with Color Coding - A garment configured to be worn by a human includes an inner surface, an outer surface, and a color-coded size indicia. The inner surface is configured to face toward the human. The outer surface is positioned opposite the inner surface on the garment and is configured to face away from the human. The garment further includes at least one opening configured to receive a body part of the human. The color-coded size indicia is provided on the inner surface of the garment. The colored-coded size indicia is not visible from an exterior of the garment when the garment is worn by the human. | 08-29-2013 |
Helena Lam, Thousand Oaks, CA US
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20090283441 | Cosmetics kit - A cosmetics kit including a fountain is described. The cosmetics kit comprises a base with a fountain attached for circulating a fluid and at least one cosmetic connectable with the base. Additionally, a mixing bowl connectable with the base is included to allow the user to mix custom cosmetics such as lip gloss and perfume with mixing accessories included with the cosmetics kit. Furthermore, a scented oil is added to the circulating fluid in the fountain to create an aromatherapy experience. | 11-19-2009 |
Helena Larsson, Kungalv SE
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20090039060 | Lasercutting With Scanner - The embodiments described relate to a laser cutting method suitable for cutting multilayered or painted materials such as for example car bodies. The method involves the step of scanning a low laser beam a plurality of turns along an intended cut edge. Utilizing the described cutting method, the paint located in the vicinity of the cut edge is only slightly affected by the heat generated by the laser beam. | 02-12-2009 |
Helena Litani, Thornhill CA
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20100064229 | AUTOMATIC PERSONALIZATION OF USER VISUALIZATION AND INTERACTION IN A SERVICE-ORIENTED ARCHITECTURE INTERFACE - A system for automatically generating visualization artifacts corresponding to related service operation interfaces. A user level visualization finite state machine instance is created for a specific service instance based on user activation and deactivation of service operations in the specific service instance and user selection of a start visualization state. The service operations are included in a service level visualization finite state machine instance for the specific service instance. Visualization artifacts are automatically generated based on the user level visualization finite state machine instance and parameterized entities bound to a concrete visualization component. The visualization artifacts are outputted in a service operation interface of the specific service instance for a user to visualize and interact with, resulting in the elimination of individual user unwanted server side function in the units of service operations without server side processing. | 03-11-2010 |
20100082379 | INFERENTIAL BUSINESS PROCESS MONITORING - Methods, systems and computer program products for inferential business process monitoring. Exemplary embodiments include an inferential business process monitoring method, including deriving an optimal set of key performance indicators from a service level agreement specification, determining metrics to compute the key performance indicators from the service level agreement specification, assigning and configuring monitoring agents to retrieve the metrics to obtain the key performance indicators, deploying the monitoring agents and delivering key performance indicator metrics observed by the monitoring agents. | 04-01-2010 |
20100094883 | Method and Apparatus for Integrated Entity and Integrated Operations of Personalized Data Resource Across the World Wide Web for Online and Offline Interactions - Embodiments of the invention provide a method and apparatus for integrated entity of personalized data resource across the WWW with integrated operations. Such embodiments can reside on premises (or service side) as an integrated personalized data resource which is constructed from each of a number of web applications over the Internet that fetch and provide a piece of user information. One embodiment of the invention is directed to a computer that has the method and apparatus associated with the designated user. It is operable to receive informational data from multiple information sources, wherein the data received from each source has a user or web application defined association with a plurality of semantic categories via tagging, and the data received from at least two different sources pertains to the same category (or tag). | 04-15-2010 |
Helena Ljusberg-Wahren, Hollviken SE
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20130267585 | PHARMACEUTICAL COMPOSITION HAVING A CATIONIC EXCIPIENT - A pharmaceutical composition comprising a pharmaceutically effective amount of a pharmaceutically active substance and a pharmaceutically acceptable carrier including a cationic excipient, wherein said cationic excipient is a labile ester of betaine and a lipophilic alcohol having at least one primary hydroxyl group. Also, the use of a labile ester of betaine and a lipophilic alcohol having at least a primary hydroxyl group as a cationic excipient in a carrier for a pharmaceutical composition comprising a pharmaceutically active substance. | 10-10-2013 |
Helena Lovick, Belgrade, MT US
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20150031772 | ADJUSTABLE BIOACTIVE AGENT DISPERSION WITHIN A POLYMERIC COATING - A coating comprised of a polymeric material and a bioactive agent where the properties of the casting solvent dictate the dispersion of the embedding bioactive agent. In preferred embodiments, controlled release of the bioactive agent is achieved by homogeneous dispersion of the bioactive agent within the coating. A further aspect of the invention is directed to formulations where the heterogeneous dispersion of the bioactive agent provides an initial rapid release of the bioactive agent. Methodology for production of coating formulations of the desired properties and the application of the coating to an article are also described. | 01-29-2015 |
Helena Mira Aparicio, Valencia ES
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20100047212 | USE OF THE PEDF FACTOR TO INDUCE CELL REGENERATION - Use of the PEDF factor to induce cell regeneration. The present invention refers to the use of the molecule PEDF for the manufacture of medicines to activate processes included in the group of regenerative processes, such as skin regeneration, wound healing, cell therapy for cardiac, neural, or hematopoietic regeneration. It also refers to the manufacture/use of pharmaceutical compounds that contain an efficient quantity of the PEDF factor for stem cell self-renewal. | 02-25-2010 |
Helena Modrzejewska, Warszawa PL
Helena Mora-Jensen, Copenhagen DK
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20100286091 | IMIDAZOLIDINONE COMPOUNDS, METHODS TO INHIBIT DEUBIQUITINATION AND METHODS OF TREATMENT - The present invention features imidazolidinone compounds and pharmaceutical compositions of imidazolidinone compounds. The compounds of the invention are utilized in methods of treating a deubiquitination-related disorder in a subject and inhibiting p97-associated deubiquitination. | 11-11-2010 |
Helena Myrberg, Stockholm SE
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20100279918 | Chimeric Constructs Between Cancer-Homing Peptides and Cell-Penetrating Peptides Coupled to Anticancer Drugs and/or Diagnostic Agent/Agents - A construct comprising a cancer-homing peptide, an optional linker and a cell-penetrating peptide coupled to an anticancer drug and/or a diagnostic agent is disclosed. The homing peptide is for example a linear pentapeptide such as CREKA (SEQ ID NO:1), AREKA (SEQ 5 ID NO: 23) or CREKA0 (SEQ ID NO: 23), or a cyclic nonapeptide CPGPEGAGC (SEQ ID NO:2), and the cell-penetrating peptide is for example one of the peptides SEQ ID NO:3-SEQ ID NO:20. The anticancer drug may be selected from alkylating agents, antimetabolites and cytotoxic antibiotics, and the diagnostic agent may be a fluorescent label. Further, a method of delivering an anticancer drug and/or a diagnostic agent into a cancer cell 0 comprising administration of a construct according to the invention in vivo or in vitro is described. | 11-04-2010 |
Helena Orszanska, Edmonton CA
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20110293671 | BACTERIOPHAGE COMPOSITIONS FOR TREATMENT OF BACTERIAL INFECTIONS - A respirable composition for treatment of a bacterial infection includes one or more active bacteriophages in combination with a pharmaceutically acceptable respirable carrier. The composition includes a carbohydrate carrier, and is prepared as fine powder. In another aspect, bacteriophages are provided in a liquid carrier for administration by nebulization. In one aspect, the bacteriophages have anti-bacterial activity against one or more species or strains of | 12-01-2011 |
Helena Ostolaza Etxabe, Leioa ES
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20100285068 | METHOD FOR THE INTERNALIZATION OF NON-INVASIVE BACTERIA IN EUKARYOTE CELLS - The present invention relates to the use of adenylate cyclase toxin (ACT), or a functionally equivalent variant thereof, as an inducing agent for the internalization of non-invasive bacteria in eukaryotic cells. Due to ACT, said non-invasive bacterium can move through the plasma membrane of a eukaryotic cell and transfer plasmid DNA to said cell, which is useful for releasing or introducing molecules of therapeutic interest, for example, antigens, in the interior of the eukaryotic cell, thereby triggering the immune response. | 11-11-2010 |
Helena Päbel, Sandviken SE
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20100322727 | DRILLING TOOL OF THE LOOSE TOP TYPE - A drilling tool of the loose top type includes a basic body having two bendable branches having inner support surfaces that are resiliently pressable against side contact surfaces of a replaceable loose top. The mounting of the loose top is affected by turning-in from an initial position to an operative end position. An abutting edge along each side contact surface then bends out the branches and subjects the branches to a spring force that reaches a maximum in a dead position so as to then decrease somewhat up to the operative end position. During the final phase of the rotary motion, the operator obtains, in a tactile and/or auditory way, confirmation of the loose top indeed reaching its operative end position. | 12-23-2010 |
20100322729 | DRILLING TOOL FOR CHIP REMOVING MACHINING AS WELL AS A LOOSE TOP AND A BASIC BODY THEREFOR - A loose top for drilling tools, including front and rear ends, a pair of envelope part surfaces concentric with a center axis, and two chip flutes countersunk in relation to the pair of envelope part surfaces between which two bars project radially from a central core, the front end including a cutting edge and at least one clearance surface positioned rotationally behind the cutting edge, the rear end forming an axial contact surface. The loose top includes two opposite side contact surfaces against which elastically bendable branches of a tool basic body are pressed in use, a pair of convex guide surfaces situated axially behind the side contact surfaces, the guide surfaces being concentric with the center axis and radially spaced-apart from the center axis at a distance that is less than the radial distance between the center axis and a respective side contact surface, and a pair of torque-carrying tangential contact surfaces that are situated radially inside the envelope part surfaces and outside the side contact surfaces. The axial contact surface extends perpendicular to the center axis between borderlines adjacent to the two envelope part surfaces. | 12-23-2010 |
Helena Päbel, Sandviken SE
Patent application number | Description | Published |
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20100322727 | DRILLING TOOL OF THE LOOSE TOP TYPE - A drilling tool of the loose top type includes a basic body having two bendable branches having inner support surfaces that are resiliently pressable against side contact surfaces of a replaceable loose top. The mounting of the loose top is affected by turning-in from an initial position to an operative end position. An abutting edge along each side contact surface then bends out the branches and subjects the branches to a spring force that reaches a maximum in a dead position so as to then decrease somewhat up to the operative end position. During the final phase of the rotary motion, the operator obtains, in a tactile and/or auditory way, confirmation of the loose top indeed reaching its operative end position. | 12-23-2010 |
20100322729 | DRILLING TOOL FOR CHIP REMOVING MACHINING AS WELL AS A LOOSE TOP AND A BASIC BODY THEREFOR - A loose top for drilling tools, including front and rear ends, a pair of envelope part surfaces concentric with a center axis, and two chip flutes countersunk in relation to the pair of envelope part surfaces between which two bars project radially from a central core, the front end including a cutting edge and at least one clearance surface positioned rotationally behind the cutting edge, the rear end forming an axial contact surface. The loose top includes two opposite side contact surfaces against which elastically bendable branches of a tool basic body are pressed in use, a pair of convex guide surfaces situated axially behind the side contact surfaces, the guide surfaces being concentric with the center axis and radially spaced-apart from the center axis at a distance that is less than the radial distance between the center axis and a respective side contact surface, and a pair of torque-carrying tangential contact surfaces that are situated radially inside the envelope part surfaces and outside the side contact surfaces. The axial contact surface extends perpendicular to the center axis between borderlines adjacent to the two envelope part surfaces. | 12-23-2010 |
20110236145 | ROTATABLE TOOL FOR CHIP REMOVING MACHINING AS WELL AS A LOOSE TOP AND A BASIC BODY THEREFOR - A rotatable tool for chip removing machining, including a basic body having front and rear ends between which there extends a first geometrical center axis (C | 09-29-2011 |
Helena Pardo Minetti, Montevideo UY
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20120128929 | Process of Preparing Magnetic Graphitic Materials, and Materials Thereof - A process of preparing magnetic graphitic materials from graphite in a second container ( | 05-24-2012 |
Helena Pardos Minetti, Montevideo UY
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20080237533 | Process for Preparing Magnetic Graphitic Materials, and Materials Thereof - A process of preparing magnetic graphitic materials from graphite in a second container ( | 10-02-2008 |
Helena Peuranen, Espoo FI
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20130184407 | METHOD FOR CONTROLLING SIZE DISTRIBUTION OF POLYMER PARTICLES DURING PREPARATION OF AQUEOUS POLYMER DISPERSION AND AQUEOUS POLYMER DISPERSION - The present disclosure relates to a method for controlling size distribution of formed polymer particles during preparation of aqueous polymer dispersion. The method comprises obtaining an aqueous polysaccharide solution, which comprises about 10 to 40 weight-% polysaccharide containing a free hydroxyl group, such as starch, and polymerising in the polysaccharide solution in the presence of a graft-linking, water-soluble redox system about 30 to 60 weight-% of at least one optionally substituted styrene, about 60 to 30 weight-% of at least one C1-C4-alkyl (meth)acrylate, and 0 to about 10 weight-% of other ethylenically unsaturated copolymerizable monomers. The size distribution of the formed polymer particles is controlled by adjusting viscosity of the polysaccharide solution before the polymerisation to a level less than about 20 mPas. The present disclosure relates also to an aqueous polymer dispersion having the D(99) value less than about 160 nm for polymer particles in the polymer dispersion and its use. | 07-18-2013 |
20150025194 | METHOD FOR CONTROLLING SIZE DISTRIBUTION OF POLYMER PARTICLES DURING PREPARATION OF AQUEOUS POLYMER DISPERSION AND AQUEOUS POLYMER DISPERSION - The present disclosure relates to a method for controlling size distribution of formed polymer particles during preparation of aqueous polymer dispersion. The method comprises obtaining an aqueous polysaccharide solution, which comprises about 10 to 40 weight-% polysaccharide containing a free hydroxyl group, such as starch, and polymerising in the polysaccharide solution in the presence of a graft-linking, water-soluble redox system about 30 to 60 weight-% of at least one optionally substituted styrene, about 60 to 30 weight-% of at least one C1-C4-alkyl(meth)acrylate, and 0 to about 10 weight-% of other ethylenically unsaturated copolymerizable monomers. The size distribution of the formed polymer particles is controlled by adjusting viscosity of the polysaccharide solution before the polymerisation to a level less than about 20 mPas. The present disclosure relates also to an aqueous polymer dispersion having the D(99) value less than about 160 nm for polymer particles in the polymer dispersion and its use. | 01-22-2015 |
Helena Peurasaari, Molnlycke SE
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20090069770 | MULTI FUNCTION WRAPPER - The invention refers to a packing wrapper ( | 03-12-2009 |
Helena Princ, Novo Mesto SI
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20130171212 | Stable Aqueous Formulations Comprising Poorly Water Soluble Active Ingredients - A formulation includes one or more active ingredients of poor water solubility for medical or non-medical use in the rearing of animals. The formulation is suitable for administration to the animals via their drinking water. It exhibits superior stability. The formulation comprises an active ingredient, a thickener combination and water, wherein the thickener combination comprises at least one thickener selected from the following groups A, B, C and D: | 07-04-2013 |
Helena Reuterwall, Solna SE
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20120308549 | PROCESS FOR PRODUCTION AND PURIFICATION OF RECOMBINANT LYSOSOMAL ALPHA-MANNOSIDASE - The present invention relates to a process for purification of recombinant alpha-mannosidase, a process for production of alpha-mannosidase, a composition comprising alpha-mannosidase, use of the composition as a medicament, use as a medicament for the treatment of alpha-mannosidosis and a method of treating alpha-mannosidosis and/or alleviating the symptoms of alpha-mannosidosis. | 12-06-2012 |
Helena Skoglar, Uppsala SE
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20120091063 | METHOD IN A CHROMATOGRAPHY SYSTEM - A method for determining binding capacities of a chromatography column ( | 04-19-2012 |
Helena Stadniychuk, Eagan, MN US
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20100327248 | CELL PATTERNING WITH MULTIPLE HARD MASKS - A method of making a memory cell or magnetic element by using two hard masks. The method includes first patterning a second hard mask to form a reduced second hard mask, with a first hard mask being an etch stop for the patterning process, and then patterning the first hard mask to form a reduced first hard mask by using the reduced second hard mask as a mask and using an etch stop layer as an etch stop. After patterning both hard masks, then patterning a functional layer by using the reduced first hard mask as a mask. In the resulting memory cell, the first hard mask layer is also a top lead, and the diameter of the first hard mask layer is at least essentially the same as the diameter of the etch stop layer, the adhesion layer, and the functional layer. | 12-30-2010 |
Helena Ticha, Czech Republic CZ
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20110062469 | MOLDED LENS INCORPORATING A WINDOW ELEMENT - A light emitter includes a light-emitting device (LED) die and an optical element over the LED die. The optical element includes a lens, a window element, and a bond at an interface disposed between the lens and the window element. The window element may be a wavelength converting element or an optically flat plate. The window element may be directly bonded or fused to the lens, or the window element may be bonded by one or more intermediate bonding layers to the lens. The bond between the window element and the lens may have a refractive index similar to that of the window element, the lens, or both. | 03-17-2011 |
Helena Ticha, Srch CZ
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20090173960 | SEMICONDUCTOR LIGHT EMITTING DEVICE WITH PRE-FABRICATED WAVELENGTH CONVERTING ELEMENT - A semiconductor light emitting device is provided with a separately fabricated wavelength converting element. The wavelength converting element, of e.g., phosphor and glass, is produced in a sheet that is separated into individual wavelength converting elements, which are bonded to light emitting devices. The wavelength converting elements may be grouped and stored according to their wavelength converting properties. The wavelength converting elements may be selectively matched with a semiconductor light emitting device, to produce a desired mixture of primary and secondary light. | 07-09-2009 |
20100109568 | COMMON OPTICAL ELEMENT FOR AN ARRAY OF PHOSPHOR CONVERTED LLIGHT EMITTING DEVICES - A device is provided with an array of a plurality of phosphor converted light emitting devices (LEDs) that produce broad spectrum light. The phosphor converted LEDs may produce light with different correlated color temperature (CCT) and are covered with an optical element that assists in mixing the light from the LEDs to produce a desired correlated color temperature. The optical element may be bonded to the phosphor converted light emitting devices. The optical element may be a dome mounted over the phosphor converted light emitting devices and filled with an encapsulant. | 05-06-2010 |
20120043564 | COMMON OPTICAL ELEMENT FOR AN ARRAY OF PHOSPHOR CONVERTED LIGHT EMITTING DEVICES - A device is provided with at least one light emitting device (LED) die mounted on a submount with an optical element subsequently thermally bonded to the LED die. The LED die is electrically coupled to the submount through contact bumps that have a higher temperature melting point than is used to thermally bond the optical element to the LED die. In one implementation, a single optical element is bonded to a plurality of LED dice that are mounted to the submount and the submount and the optical element have approximately the same coefficients of thermal expansion. Alternatively, a number of optical elements may be used. The optical element or LED die may be covered with a coating of wavelength converting material. In one implementation, the device is tested to determine the wavelengths produced and additional layers of the wavelength converting material are added until the desired wavelengths are produced. | 02-23-2012 |
20130293145 | BONDING AN OPTICAL ELEMENT TO A LIGHT EMITTING DEVICE - A device is provided with at least one light emitting device (LED) die mounted on a submount with an optical element subsequently thermally bonded to the LED die. The LED die is electrically coupled to the submount through contact bumps that have a higher temperature melting point than is used to thermally bond the optical element to the LED die. In one implementation, a single optical element is bonded to a plurality of LED dice that are mounted to the submount and the submount and the optical element have approximately the same coefficients of thermal expansion. Alternatively, a number of optical elements may be used. The optical element or LED die may be covered with a coating of wavelength converting material. In one implementation, the device is tested to determine the wavelengths produced and additional layers of the wavelength converting material are added until the desired wavelengths are produced. | 11-07-2013 |
Helena Tlaskalova-Hogenova, Prague CZ
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20090118173 | TREATMENT AND PREVENTION OF INFLAMMATORY BOWEL DISEASES - The present invention relates to the use of heat shock proteins, or fragments thereof, for the treatment and/or prevention of Inflammatory Bowel Diseases. Preferably bacterial and/or mammalian heat shock proteins belonging to the HSP70 families are used. | 05-07-2009 |
Helena Twardowska, Cincinnati, OH US
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20120034373 | MATERIAL AND APPLICATOR FOR PINHOLE AND SMALL DEFECT REPAIR - A method for finishing a repaired surface is described. The method includes wiping a sealer on the repaired surface to seal microporosity in the repaired surface, the sealer consisting essentially of a mixture of polymer, at least one filler, solvent, and optionally microspheres; and applying a top coat to the sealed surface without sanding the sealed surface, the top coat being free of visible pinholes. Sealers and tools for applying surface sealers are also described. | 02-09-2012 |
20120040173 | LOW DENSITY CORING MATERIAL - A low density coring material is described. In one embodiment, the low density coring material consists essentially of: about 40 to about 80 wt % resin; 0 to about 50 wt % monomer; 0 to about 5 wt % dispersion aid; 0 to about 5 wt % accelerator; about 3 to about 7 wt % microspheres; and about 1 to about 5 wt % catalyst; wherein a density of the cured coring material is less than about 5.0 lbs/gal. Composites made using the low density coring material and methods of making composites are also described. | 02-16-2012 |
20120040174 | LOW DENSITY CORING MATERIAL - A low density coring material is described. In one embodiment, the low density coring material consists essentially of: about 40 to about 80 wt % resin, the resin consisting essentially of vinyl ester resin or a combination of vinyl ester resin and polyester resin; 0 to about 50 wt % monomer; 0 to about 5 wt % dispersion aid; 0 to about 5 wt % accelerator, or inhibitor, or both; about 3 to about 10 wt % microspheres; 0 to about 20 wt % fiber; 0 to about 20 wt % filler; and about 1 to about 5 wt % catalyst; wherein a density of the cured coring material is less than about 5.0 lbs/gal. Composites made using the low density coring material and methods of making composites are also described. | 02-16-2012 |
Helena Twardowska, Loveland, OH US
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20120135147 | HIGH BUILD LOW TEMPERATURE EXOTHERM EXTRUDABLE MATERIAL - A high build tooling compound suited for plug building by extrusion process with conventional FRP dispensing equipment is described. The material is based on urethane hybrid and unsaturated polyester resin mixture with additives to provide low shrinkage and low exotherm. The formulation allows building a desired part thicknesses from 0.5 to 3 inches in one application. Methods of making a plug are also described. | 05-31-2012 |
20120295019 | COMPLETE TOOLING PACKAGES FOR MOLD BUILDING STRUCTURES - Tooling packages for mold building structures, mold structures, and methods of making mold structures are described. | 11-22-2012 |
Helena Van Den Bussche, Malmo SE
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20110207765 | TOPICAL COMPOSITION COMPRISING A COMBINATION OF AT LEAST TWO PENETRATION ENHANCING AGENTS - The present invention relates to a composition for improved transdermal drug delivery comprising a drug, a combination of at least two penetration enhancing agents, wherein at least one of the penetration enhancing agents is selected from the group consisting of esters of saturated or unsaturated fatty acids and lower alcohols, and iso-form alcohols; wherein at least one of the penetration enhancing agents is selected from the group consisting of aliphatic diols and triols; and wherein the components are present in a non-aqueous solvent system. A preferred topical composition comprises the active substance imiquimod and the penetration enhancing agents isopropyl myristate and propylene glycol. | 08-25-2011 |
20130202650 | TOPICAL COMPOSITION COMPRISING A COMBINATION OF AT LEAST TWO PENETRATION ENHANCING AGENTS - The present invention relates to a composition for improved transdermal drug delivery comprising a drug, a combination of at least two penetration enhancing agents, wherein at least on the of the penetration enhancing agents is selected from the group consisting of esters of saturated or unsaturated fatty acids and lower alcohols, and iso-form alcohols; wherein at least one of the penetration enhancing agents is selected from the group consisting of aliphatic diols and triols; and wherein the components are present in a non-aqueous solvent system. A preferred topical composition comprises the active substance imiquimod and the penetration enhancing agents isoproply myristate and propylene glycol. | 08-08-2013 |
Helena Varela Rizo, Alicante ES
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20120208022 | PROCEDURE FOR OBTAINING GRAPHENE OXIDE NANO-PLATELETS AND DERIVATES AND GRAPHENE OXIDE NON-PLATELETS THUS OBTAINED - A method for manufacturing graphene oxide nanoplatelets and derivative products and the graphene oxide nanoplatelets obtained, comprising two distinct phases, a first phase for obtaining an intermediate material consisting of carbon nanofilaments, each one having a structure comprising continuous ribbon of graphitic material with a small number of stacked monoatomic graphene layers and spirally rolled around and along the main axis of said nanofilaments, and a second phase wherein said carbon nanofilaments are subjected to a high-temperature treatment in order to clean said filaments and increase their degree of crystallinity. Once these nanofilaments are treated, a chemical etching is performed on them comprising an oxidation that causes the fragmentation of the carbon nanofilaments and starts a cleaving method that is completed by physical means in order to obtain graphene oxide nanoplatelets. | 08-16-2012 |
Helena Weaks, Maineville, OH US
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20140324276 | ENGINE DIAGNOSTIC SYSTEM FOR HIGH VOLUME FEEDBACK PROCESSING - An engine diagnostic system in accordance with an embodiment not only captures the written feedback from each technician, but also tracks every step/click that the technician took during the diagnostic process and classifies those clicks into desirable or undesirable behavior patterns that indicate missing or miss-tagged content, inefficiently presented materials, or training issues such as not following troubleshooting guidance. The system provides daily updates of troubleshooting status's of diagnoses being conducted on millions of engine systems that represent a great amount of different engine models and types from around the globe, and provides data reduction techniques and metrics that guides the analyst/service engineers to high priority emerging issues reduced to specific actionable events that can be corrected and immediately monitored for their impacts on the troubleshooting system efficiency measures. Therefore, the technician not only provides direct information through purposeful feedback, he is also providing very valuable but less direct information through tracking his interactions with the system. | 10-30-2014 |
Helena Widegren, Uppsala SE
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20120267299 | METHOD FOR DRY PACKING CHROMATOGRAPHY COLUMNS - The invention provides a packing method for high efficiency chromatography columns starting from dry swellable particles, as well as columns packed by the method and the use of the columns in separation of biomolecules. In the packing method, an amount of dry swellable particles sufficient to give a swollen volume in a liquid of about 105-120% of the column chamber volume is transferred to the column, the column is closed and the liquid is provided to the column. | 10-25-2012 |
Helena Woodvine, Tacoma Park, MD US
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20130144142 | Anti-Interferent Barrier Layers for Non-Invasive Transdermal Sampling and Analysis Device - A system and methods are provided for reducing electrochemical interference in a transdermal sampling and analysis device. A one-step transdermal glucose biosensor may calculate glucose concentrations that are artificially high compared to traditional home blood glucose sensors due to interference, which may be mitigated by forming an anti-interferent barrier layer over a sensing element. The anti-interferent barrier layer may be formed over a sensing layer and may possess a charge type which repels interferent molecules having the same charge type from interacting with the sensing layer disposed below the anti-interferent barrier layer. | 06-06-2013 |
Helena Yusuf-Makagiansar, San Diego, CA US
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20100068693 | Nutrient Monitoring and Feedback Control for Increased Bioproduct Production - The present invention pertains to methods of increasing the efficiency of producing a bioproduct. In some embodiments, the method increases the quantity of a bioproduct produced, or decreases bioproduct production time, in a bioreactor cell culture producing the bioproduct, the method comprising, (a) intermittently or continuously analyzing the concentration of one or more nutrients in the bioreactor cell culture; and (b) adding to the bioreactor cell culture additional nutrient media when the concentration of the one or more nutrients is lower than a target value. | 03-18-2010 |
20130065219 | Nutrient Monitoring and Feedback Control for Increased Bioproduct Production - The present invention pertains to methods of increasing the efficiency of producing a bioproduct. In some embodiments, the method increases the quantity of a bioproduct produced, or decreases bioproduct production time, in a bioreactor cell culture producing the bioproduct, the method comprising, (a) intermittently or continuously analyzing the concentration of one or more nutrients in the bioreactor cell culture; and (b) adding to the bioreactor cell culture additional nutrient media when the concentration of the one or more nutrients is lower than a target value. | 03-14-2013 |
20130096283 | Method of Supplementing Culture Media to Prevent Undesirable Amino Acid Substitutions - The present invention relates to methods of reducing substitution of amino acids during the production of polypeptides of interest in mammalian cells. By varying the concentration of amino acids in the culture medium, heterogeneity of the polypeptide's amino acid sequence is decreased, leading to higher yields of functional protein. | 04-18-2013 |
20140363845 | CHOLESTEROL-BASED MEDIA SUPPLEMENTS FOR CELL CULTURE - The disclosure provides compositions and methods for high density cell culture and banking of cholesterol auxotrophic cells. | 12-11-2014 |
Helena Zelmanovich, Deer Park, NY US
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20080198816 | MULTIPLE APPEARANCE PROTOCOL FOR TIMELY ORGANIZED AD HOC NETWORK - The present invention comprises a plurality of timely organized ad hoc data communications networks and a method for data communication. A network from the plurality of networks includes media-independent communications links and plurality of network nodes, where a network node in the plurality could be coupled to at least one other network node via a media independent communication link, and a plurality of access points, where each access point in the plurality is coupled to at least one other access point via another media-independent communications link. The network communicates during a data collection cycle that includes a broadcast interval, a time-slotted communications interval and a random access time-slotted communications interval. The plurality of network nodes are arranged in a self-assigned hierarchy where one or more nodes in the plurality of network nodes can be assigned more than one time slot to transmit the network information messages. | 08-21-2008 |
20140119236 | TOPOGRAPHICAL DISPLAY GENERATOR FOR AD HOC NETWORK - The present invention comprises a computer apparatus for displaying the topology of a timely organized ad hoc network, the apparatus including a processor, a memory, a computer-readable medium, an input device coupled to the processor, a radio frequency transceiver coupled to the processor; a communications interface coupled to the memory, a display coupled to the processor, and software copied from the computer-readable medium into the memory by the processor that, when executed, causes the processor to obtain a diagram of the network location from the input device or computer readable medium, obtain the identities of the devices comprising the network from the input device or computer readable medium, determine the communication links between the network devices, and graphically represent on the display the devices and the connection links on the diagram. | 05-01-2014 |
20140192787 | MULTIPLE APPEARANCE PROTOCOL FOR TIMELY ORGANIZED AD HOC NETWORK - The present invention comprises a plurality of timely organized ad hoc data communications networks and a method for data communication. A network from the plurality of networks includes media-independent communications links and plurality of network nodes, where a network node in the plurality could be coupled to at least one other network node via a media independent communication link, and a plurality of access points, where each access point in the plurality is coupled to at least one other access point via another media-independent communications link. The network communicates during a data collection cycle that includes a broadcast interval, a time-slotted communications interval and a random access time-slotted communications interval. The plurality of network nodes are arranged in a self-assigned hierarchy where one or more nodes in the plurality of network nodes can be assigned more than one time slot to transmit the network information messages. | 07-10-2014 |
Helena Zelmanovick, Deer Park, NY US
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20100115414 | TOPOGRAPHICAL DISPLAY GENERATOR FOR AD HOC NETWORK - The present invention comprises a computer apparatus for displaying the topology of a timely organized ad hoc network, the apparatus including a processor, a memory, a computer-readable medium, an input device coupled to the processor, a radio frequency transceiver coupled to the processor; a communications interface coupled to the memory, a display coupled to the processor, and software copied from the computer-readable medium into the memory by the processor that, when executed, causes the processor to obtain a diagram of the network location from the input device or computer readable medium, obtain the identities of the devices comprising the network from the input device or computer readable medium, determine the communication links between the network devices, and graphically represent on the display the devices and the connection links on the diagram. | 05-06-2010 |