Patent application number | Description | Published |
20080204022 | Biological detector and method - A biological detector includes a conduit for receiving a fluid containing one or more magnetic nanoparticle-labeled, biological objects to be detected and one or more permanent magnets or electromagnet for establishing a low magnetic field in which the conduit is disposed. A microcoil is disposed proximate the conduit for energization at a frequency that permits detection by NMR spectroscopy of whether the one or more magnetically-labeled biological objects is/are present in the fluid. | 08-28-2008 |
20080272788 | Microcoil NMR Detectors - The present invention provides resonance circuits, detection devices incorporating such circuits, and methods for their design, construction, and use. | 11-06-2008 |
20090146658 | Microcoil Magnetic Resonance Detectors - The present invention provides microcoil magnetic resonance based modules, detection devices, and methods for their use. | 06-11-2009 |
20090256572 | Tuning Low-Inductance Coils at Low Frequencies - A method and apparatus for tuning and matching extremely small sample coils with very low inductance for use in magnetic resonance experiments conducted at low frequencies. A circuit is disclosed that is appropriate for performing measurements in fields where magnetic resonance is beneficially utilized. The circuit has a microcoil, an adjustable tuning capacitance, and added inductance in the form of a tuning inductor. The microcoil is an electrical coil having an inductance of about 25 nanohenries (nH) or less. Because additional inductance is purposefully added, the capacitance required for resonance and apparatus function is proportionally and helpfully reduced. The apparatus and method permit the resonant circuit and the magnet to be made extremely small, which is crucial for new applications in portable magnetic resonance imaging, for example. | 10-15-2009 |
20100219824 | BIOLOGICAL DETECTOR AND METHOD - A biological detector includes a conduit for receiving a fluid containing one or more magnetic nanoparticle-labeled, biological objects to be detected and one or more permanent magnets or electromagnet for establishing a low magnetic field in which the conduit is disposed. A microcoil is disposed proximate the conduit for energization at a frequency that permits detection by NMR spectroscopy of whether the one or more magnetically-labeled biological objects is/are present in the fluid. | 09-02-2010 |
20110262893 | SEPARATING TARGET ANALYTES USING ALTERNATING MAGNETIC FIELDS - The invention generally relates to using magnetic particles and alternating magnet fields to separate a target analyte from a sample. In certain embodiments, methods of the invention involve contacting a sample with magnetic particles including first moieties specific for a target analyte, thereby forming target/particle complexes in the sample, flowing the sample through a channel including second moieties attached to at least one surface of the channel, applying alternating magnetic fields to the flowing sample to result in target/particle complexes being brought into proximity of the surface to bind the second moieties and unbound particles remaining free in the sample, binding the target/particle complexes to the second moieties, and washing away unbound particles and unbound analytes of the sample. | 10-27-2011 |
20120112744 | MICROCOIL MAGNETIC RESONANCE DETECTORS - The present invention provides microcoil magnetic resonance based modules, detection devices, and methods for their use. | 05-10-2012 |
20130127464 | BIOLOGICAL DETECTOR AND METHOD - A biological detector includes a conduit for receiving a fluid containing one or more magnetic nanoparticle-labeled, biological objects to be detected and one or more permanent magnets or electromagnet for establishing a low magnetic field in which the conduit is disposed. A microcoil is disposed proximate the conduit for energization at a frequency that permits detection by NMR spectroscopy of whether the one or more magnetically-labeled biological objects is/are present in the fluid. | 05-23-2013 |
20130169276 | BIOLOGICAL DETECTOR AND METHOD - A biological detector includes a conduit for receiving a fluid containing one or more magnetic nanoparticle-labeled, biological objects to be detected and one or more permanent magnets or electromagnet for establishing a low magnetic field in which the conduit is disposed. A microcoil is disposed proximate the conduit for energization at a frequency that permits detection by NMR spectroscopy of whether the one or more magnetically-labeled biological objects is/are present in the fluid. | 07-04-2013 |
20140295486 | BIOLOGICAL DETECTOR AND METHOD - A biological detector includes a conduit for receiving a fluid containing one or more magnetic nanoparticle-labeled, biological objects to be detected and one or more permanent magnets or electromagnet for establishing a low magnetic field in which the conduit is disposed. A microcoil is disposed proximate the conduit for energization at a frequency that permits detection by NMR spectroscopy of whether the one or more magnetically-labeled biological objects is/are present in the fluid. | 10-02-2014 |
Patent application number | Description | Published |
20100141255 | Nuclear Magnetic Resonance Apparatus, Methods and Associated Technology - NMR technology disclosed herein, such as an NMR apparatus or an NMR method, for example, may be useful for purposes described herein, such as determining presence or absence of magnetic resonance from a sample, for example. Methods pertaining to such NMR technology include methods of designing or constructing NMR apparatus, methods of using NMR apparatus, methods of employing data obtained from NMR apparatus, and/or the like. Various apparatus and methods for detection of magnetic resonance in sample material are disclosed herein. Additionally, various apparatus and methods for usefully employing magnetic resonance data are disclosed herein. | 06-10-2010 |
20100225315 | Tuning Low-Inductance Coils at Low Frequencies - A method and apparatus for tuning and matching extremely small sample coils with very low inductance for use in magnetic resonance experiments conducted at low frequencies. A circuit is disclosed that is appropriate for performing measurements in fields where magnetic resonance is beneficially utilized. The circuit has a microcoil, an adjustable tuning capacitance, and added inductance in the form of a tuning inductor. The microcoil is an electrical coil having an inductance of about 25 nanohenries (nH) or less. Because additional inductance is purposefully added, the capacitance required for resonance and apparatus function is proportionally and helpfully reduced. The apparatus and method permit the resonant circuit and the magnet to be made extremely small, which is crucial for new applications in portable magnetic resonance imaging, for example. | 09-09-2010 |