Muthusamy
Muthusamy Jayraman, Cambridge, MA US
Patent application number | Description | Published |
---|---|---|
20090163705 | CATIONIC LIPIDS - Cyclic lipid moieties are described herein. | 06-25-2009 |
20120035115 | CHEMICAL MODIFICATIONS OF MONOMERS AND OLIGONUCLEOTIDES WITH CYCLOADDITION - The invention features compounds of formula I or II: | 02-09-2012 |
Muthusamy Jayraman, Sharon, MA US
Patent application number | Description | Published |
---|---|---|
20090023673 | LIPID CONTAINING FORMULATIONS - Compositions and methods useful in administering nucleic acid based therapies, for example association complexes such as liposomes and lipoplexes are described. | 01-22-2009 |
20120046478 | LIPID CONTAINING FORMULATIONS - Compositions and methods useful in administering nucleic acid based therapies, for example association complexes such as liposomes and lipoplexes are described. | 02-23-2012 |
Muthusamy Shanmugan, Monmouth Junction, NJ US
Patent application number | Description | Published |
---|---|---|
20100272781 | Sugar Free Chewable Tablets - This invention relates to chewable tablets containing medicants such as gastrointestinal drugs. More particularly, the invention relates to chewable tablets of medicaments that are sugar free and have reduced calories. Accordingly, the tablets of the invention are suitable for both diabetic and non-diabetic patients. | 10-28-2010 |
20100305515 | Locking Mechanism for Drug Delivery System - The invention relates to a locking mechanism for adjustable systems for delivering a specified dosage of a substance. The delivery system can be used to deliver, for example, a drug or a nutritional supplement to a human or veterinary patient or for delivering, for example, fertilizer in agricultural use. | 12-02-2010 |
Muthusamy Thangaraju, Evans, GA US
Patent application number | Description | Published |
---|---|---|
20100137236 | Compositions Comprising a GPR109 Ligand For Treating Disorders of the Digestive Tract and/or Cancer - Pharmaceutical compositions containing an effective amount of a ligand for GPR109 to decrease intracellular cAMP levels of a subject in combination with an effective amount of a DNA methyl transferase inhibito to reduce or inhibit downregulation of GPR109 in the intestinal epithelial cells of the subject relative to a control are provided. It has been discovered that ligands for GPR109 can be used to treat one or more symptoms of cancer, inflammatory disorders, and diarrhea. Representative CPR 109 ligands include, but are not limited to butyrate, β-hydroxybutyrate, nicotinic acid, acifran, and octanoate. Suitable DNA methyl transferase inhibitors include 5-azacytidine, 5-aza-2′-deoxytidine, 1-β-D-arabinfαmosyl-5-azacytosine and dihydro-5-azacytidine. Typically, the compositions are formulated to achieve a GPR 109 ligand serum blood level of about 1 to about 1000 μM. The compositions are useful for the treatment of one or more symptoms of cancer. Preferred cancers that can be treated using the disclosed compositions include, but are not limited to colon cancer, breast cancer and leukemia. Methods for treating cancer, inflammatory disorders, and diarrhea are also provided. | 06-03-2010 |
20100305184 | INHIBITORS OF THE ATB(0,+) TRANSPORTER AND USES THEREOF - The present invention includes inhibitors of the amino acid transporter ATB | 12-02-2010 |
20130230512 | INHIBITORS OF THE ATB(0,+) TRANSPORTER AND USES THEREOF - The present invention includes inhibitors of the amino acid transporter ATB | 09-05-2013 |
20140024663 | ATB(0,+) AMINO ACID TRANSPORTER AS A DRUG TARGET FOR TREATMENT OF ESTROGEN RECEPTOR-POSITIVE BREAST CANCER - The present invention includes inhibitors of the amino acid transporter ATB | 01-23-2014 |
Muthusamy Vembusubramanian, Acton, MA US
Patent application number | Description | Published |
---|---|---|
20090283258 | CONTINUOUS FIBERS FOR USE IN HYDRAULIC FRACTURING APPLICATIONS - Methods and related systems are described for use with hydraulic fracturing and other oilfield applications. A tool body is positioned in a wellbore at a location near a subterranean rock formation being fractured. The tool body contains a plurality of deployable continuous fibers. At least some of the deployable continuous fibers are deployed into fractures within a subterranean rock formation. Each deployed fiber is continuous from the tool body to the rock formation. The number of deployable continuous fibers provides sufficient redundancy to make at least a target measurement relating to the fracturing process. | 11-19-2009 |
20090283259 | SENSING AND MONITORING OF ELONGATED STRUCTURES - Methods and related systems are described for use with a wireline tool system including a wireline cable designed to deploy a wireline tool into a wellbore from the surface, the wireline cable having one or more conducting members for communication between the wireline tool and the surface; and a plurality of sensing elements located on the wireline cable in a spaced apart fashion along substantially the entire length of the wireline cable, each sensing element being in communication with one or more adjacent sensing elements. | 11-19-2009 |
20090283261 | CONTINUOUS FIBERS FOR USE IN WELL COMPLETION, INTERVENTION, AND OTHER SUBTERRANEAN APPLICATIONS - Methods and related systems are described for use with continuous fiber based system for use with well bore completions comprising: a plurality of continuous fibers deployable into a portion of a well bore completion; a fiber management module adapted and positioned within the borehole to facilitate deployment of and communication with the plurality of continuous fibers; wherein the number of deployable continuous fibers provides sufficient redundancy to make at least a target measurement relating to the completion. | 11-19-2009 |
20090285051 | SENSING AND ACTUATING IN MARINE DEPLOYED CABLE AND STREAMER APPLICATIONS - Methods and related systems are described for use with hydraulic fracturing and other oilfield applications. A tool body is positioned in a wellbore at a location near a subterranean rock formation being fractured. The tool body contains a plurality of deployable continuous fibers. At least some of the deployable continuous fibers are deployed into fractures within a subterranean rock formation. Each deployed fiber is continuous from the tool body to the rock formation. The number of deployable continuous fibers provides sufficient redundancy to make at least a target measurement relating to the fracturing process. | 11-19-2009 |
20100000215 | ZERO EMISSION NATURAL GAS POWER AND LIQUEFACTION PLANT - A zero-emissions power plant receives natural gas from wells at elevated pressure and temperature. Gas is expanded through one or more turbo-expanders, preferably reformed, and sent to a fuel cell where electricity, heat, carbon-dioxide, and water are generated. The carbon-dioxide is compressed by at least one compressor and piped downhole for sequestration. The turbo-expanders have shafts which preferably share the shafts of the compressors. Thus, energy given up by the natural gas in the turbo-expanders is used to run compressors which compress carbon dioxide for downhole sequestration. In one embodiment, the natural gas is applied to heat exchangers in order to generate a stream of liquid natural gas. The remainder of the gas is expanded through the turbo-expanders and processed in the reformer prior to being sent to the fuel cell. A shifter may be used between the reformer and fuel cell. A solid oxide fuel cell is preferred. | 01-07-2010 |