Ziogas
Agryrios Ziogas, Irvine, CA US
Patent application number | Description | Published |
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20100166707 | EXTRACELLULAR MATRIX/METASTASIS MODIFIER GENES FOR THE PREVENTION OR INHIBITION OF METASTASIS OR GROWTH OF TUMOR AND FOR CHARACTERIZATION OF TUMOR - Disclosed are methods involving the administration of an extracellular matrix (ECM)/metastasis modifier gene, e.g., Anakin, Necdin, CentaurinD3 (CentD3), Csf1r, Brd4, Pi16, and Luc7l, for the prevention or inhibition of metastasis or of tumor growth. Further disclosed are methods of characterizing a tumor or cancer in a subject comprising detecting (i) a single nucleotide polymorphism (SNP) in an Anakin gene or a Brd4 gene of the subject, (ii) an amino acid substitution in an Anakin protein in the subject, or (iii) a level of expression of an Anakin gene or a Brd4 gene in the subject. Methods of screening a compound for anti-cancer activity and use of a compound with anti-cancer activity for the preparation of a medicament to treat or prevent cancer in a subject are also disclosed. Also disclosed is a method of inhibiting Sipa-1 in a subject. | 07-01-2010 |
Argyrios Ziogas, Irvine, CA US
Patent application number | Description | Published |
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20090215064 | QUANTITATIVE ASSESSMENT OF INDIVIDUAL CANCER SUSCEPTIBILITY BY MEASURING DNA DAMAGE-INDUCED MRNA IN WHOLE BLOOD - Heparinized human whole blood from patients with invasive breast cancer, with (multiple primary) and without (single primary) a second primary cancer, and from unaffected controls was stimulated with 0.1-10 Gy of radiation and incubated at 37° C. for 2 hours. P21 and PUMA mRNA were then quantified. The results suggest that cancer susceptibility represented by the multiple primary cases was significantly related to over-reaction of p21 mRNA, and not PUMA. | 08-27-2009 |
Athanassios Ziogas, Mainz DE
Patent application number | Description | Published |
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20100136699 | SAMPLE PLATE - A sample plate, portable analysis apparatus and method of analysing sulphur and/or nitrogen compounds in a sample fluid, the method comprising feeding a sample fluid to a sample plate having a sample inlet, a reaction zone, an analysis zone, and at least one separation zone, the sample plate being adapted to allow; (a) a sample fluid to be fed to the sample plate through the inlet to the reaction zone or optionally to a separation zone, which separation zone separates the sample fluid into two or more fractions at least one of which is fed to the reaction zone; (b) a reactant to be fed to the reaction zone; (c) the reaction zone to be maintained under conditions that enable reaction to occur between the reactant and the sample fluid or fraction thereof to produce a product fluid; and (d) transfer of the product fluid to the analysis zone or optionally to a separation zone in which the product fluid is separated into two or more fractions, at least one of which is transferred to the analysis zone. | 06-03-2010 |