Patent application number | Description | Published |
20120016289 | ARTICLES, COMPOSITIONS, AND METHODS FOR KILLING OR PREVENTING THE GROWTH OF MICROBES - Described herein are methods and compositions for killing or preventing the growth of microbes. It has been discovered that a class of porphyrins can kill or prevent the growth of microbes. The porphyrins can be used in a number of different applications where microbes grow. | 01-19-2012 |
20130190234 | THE USE OF ALKYLATED SEMI-SYNTHETIC GLYCOSAMINOGLYCOSAN ETHERS FOR THE TREATMENT OF DENTAL DISORDERS - Described herein are methods for treating a dental disorder in a subject comprising administering to the subject an effective amount of a modified hyaluronan or a pharmaceutically acceptable salt or ester thereof, wherein said hyaluronan or its pharmaceutically acceptable salt or ester comprises at least one sulfate group and the primary C-6 hydroxyl proton of at least one N-acetyl-glucosamine residue is substituted with a C | 07-25-2013 |
20140179742 | COMPOSITIONS FOR KILLING OR PREVENTING THE GROWTH OF MICROBES - Described herein are methods and compositions for killing or preventing the growth of microbes. It has been discovered that a class of porphyrins can kill or prevent the growth of microbes. The porphyrins can be used in a number of different applications where microbes grow. | 06-26-2014 |
20150148310 | DEUTERIUM-ENRICHED HYALURONAN - The present invention generally relates to deuterium-enriched hyaluronan, d-HA, compositions containing the same, methods of using the same, and methods for making the same. | 05-28-2015 |
Patent application number | Description | Published |
20100317616 | ALKYLATED SEMI-SYNTHETIC GLYCOSAMINOGLYCAN ETHERS, AND METHODS OF MAKING AND USING THEREOF - Described herein is the synthesis of alkylated and semi-synthetic glycosaminoglycosan ethers, referred to herein as “SAGEs.” The synthesis of sulfated alkylated SAGEs is also described. The compounds described herein are useful in a number of applications including wound healing, drug delivery, and the treatment of a number of inflammatory diseases and skin disorders. | 12-16-2010 |
20110082104 | ALKYLATED SEMI SYNTHETIC GLYCOSAMINOGLYCOSAN ETHERS, AND METHODS FOR MAKING AND USING THEREOF - Described herein is the synthesis of alkylated and semi-synthetic glycosaminoglycosan ethers, referred to herein as “SAGEs.” The synthesis of sulfated alkylated SAGEs is also described. The compounds described herein are useful in a number of applications including wound healing, drug delivery, and the treatment of a number of inflammatory diseases and skin disorders. | 04-07-2011 |
20110306581 | STABLE PERFLUOROCARBON EMULSION FOR USE AS AN ARTIFICIAL OXYGEN CARRIER - Perfluorocarbon emulsions having a high stability and good oxygen release are disclosed and described. These perfluorocarbon emulsions are typically for use as artificial oxygen carriers. The perfluorocarbon emulsions include a disperse phase of a perfluorocarbon and an emulsion stabilizer, and continuous phase. The emulsion stabilizer can primarily include a poly(ethylene oxide) block copolymer. These stabilized perfluorocarbon emulsions can be used in liquid and/or hydrogel phases of perfusion bioreactors or various other culture systems to enhance cell viability in thick tissue constructs, or as blood substitutes, although other applications may also be considered. | 12-15-2011 |
20120021968 | METHODS FOR TREATING OR PREVENTING UROLOGICAL INFLAMMATION - Described herein are methods for treating or preventing urological inflammation in a subject comprising administering to the subject an effective amount of a compound comprising
| 01-26-2012 |
20120058161 | ALKYLATED SEMI SYNTHETIC GLYCOSAMINOGLYCOSAN ETHERS, AND METHODS FOR MAKING AND USING THEREOF - Described herein are alkylated and semi-synthetic glycosaminoglycosan ethers, referred to herein as “SAGEs.” The synthesis of sulfated and alkylated SAGEs is also described. The compounds described herein are useful in a number of applications including use for ocular or ophthalmic treatment. | 03-08-2012 |
20130035307 | METHODS FOR TREATING OR PREVENTING THE SPREAD OF CANCER USING SEMI-SYNTHETIC GLYCOSAMINOGLYCOSAN ETHERS - Described herein are methods for the treatment and prevention of tumor metastasis using alkylated and fluoroalkylated semi-synthetic glycosaminoglycan ethers (“SAGEs”). The synthesis of sulfated alkylated and fluoroalkylated SAGEs is also described. | 02-07-2013 |
20130172985 | CROSSLINKED HYDROGELS AND METHODS OF MAKING AND USING THEREOF - Described herein are modified gelatins or the pharmaceutically-acceptable salts or esters thereof comprising at least one actinically crosslinkable group covalently bonded to gelatin. The modified gelatins are useful in producing composites that ultimately can be used to produce three-dimensional engineered biological constructs. The composites are the polymerization product between the modified gelatin and at least one actinically crosslinkable macromolecule. Methods for making the modified gelatins are also described herein. | 07-04-2013 |
20130209531 | APPLICATIONS OF PARTIALLY AND FULLY SULFATED HYALURONAN - Described herein is the use of partially and fully sulfated hyaluronan or the pharmaceutically acceptable salt or ester thereof for therapeutic and cosmetic applications as well as the treatment of a number of systemic, dermatological, periodontal, ophthalmic, and urological inflammatory diseases. | 08-15-2013 |
20130303539 | COMPOUNDS WITH TRPV4 ACTIVITY, COMPOSITIONS AND ASSOCIATED METHODS THEREOF - Compounds, compositions and methods useful for treating ocular diseases are provided. In particular, antagonists of TRPV4, their synthesis, pharmaceutical compositions thereof and methods of treating ocular diseases such as glaucoma, are disclosed. | 11-14-2013 |
20140343011 | METHODS FOR TREATING OR PREVENTING UROLOGICAL INFLAMMATION - Described herein are methods for treating or preventing urological inflammation in a subject comprising administering to the subject an effective amount of a compound comprising a. a modified hyaluronan or a pharmaceutically acceptable salt or ester thereof, wherein said hyaluronan or its pharmaceutically acceptable salt or ester comprises at least one sulfate group and at least one primary C-6 hydroxyl position of an N-acetyl-glucosamine residue comprising an alkyl group or fluoroalkyl group; b. a partially or fully sulfated hyaluronan or the pharmaceutically acceptable salt or ester thereof, or a combination thereof. | 11-20-2014 |
20150133411 | COMPOUNDS WITH TRPV4 ACTIVITY, COMPOSITIONS AND ASSOCIATED METHODS THEREOF - Compounds, compositions and methods useful for treating ocular diseases are provided. In particular, antagonists of TRPV4, their synthesis, pharmaceutical compositions thereof and methods of treating ocular diseases such as glaucoma, are disclosed. Compounds of the invention include N-(3-(trifluoromethyl)phenyl)-2-methyl-1-(3-morpholinopropyl)-5-phenyl-1 H-pyrrole-3-carboxamide, as well as other 2-phenyl-pyrrole carboxamide derivates and indole carboxamide derivatives. | 05-14-2015 |
20150204836 | SOLUBLE METAL SENSOR COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME - Described herein are the preparation and use of metal sensor compounds in detecting metals that are toxic to humans or to the environment. In one aspect, the metal sensor compounds comprise a polycyclic aryl group (PAC), wherein at least one solubilizing group and at least one metal binding ligand are covalently bonded to (PAC). | 07-23-2015 |