Rosana
Rosana Esteller, Marietta, GA US
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20140276181 | Methods and Systems for Automatically Identifying Detection Parameters for an Implantable Medical Device - An initial set of parameters for operating one or more detection tools is automatically derived and subsequently adjusted so that each detection tool is more or less sensitive to signal characteristics in a region of interest. Detection tool(s) may be applied to physiological signals sensed from a patient (such as EEG signals) and may be configured to run in an implanted medical device that is programmable with the parameters to look for rhythmic activity, spiking, and power changes in the sensed signals, etc. A detection tool may be selected and parameter values derived in a logical sequence and/or in pairs based on a graphical representation of an activity type which may be selected by a user, for example, by clicking and dragging on the graphic via a GUI. Displayed simulations allow a user to assess what will be detected with a derived parameter set and then to adjust the sensitivity of the set or start over as desired. | 09-18-2014 |
Rosana Gerometta, Corrientes AR
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20150366953 | GLAUCOMA TREATMENT - Disclosed herein are methods of treatment for an intraocular pressure (IOP)-associated condition in a subject, that include administering to the subject an effective amount of a tissue plasminogen activator (tPA) therapeutic agent. In one embodiment, the IOP-associated condition is glaucoma. The administration of a tPA therapeutic agent can be an extended administration intended to cause a reduction in IOP in the subject for a period of at least one day to a year or more, relative to IOP levels in the subject prior to administration of the tPA therapeutic agent. The tPA therapeutic agent can be, for example, tPA, a tPA derivative, a small molecule direct or indirect tPA agonist, or a gene therapy vector. | 12-24-2015 |
Rosana Kapellar-Libermann, Chestnut Hill, MA US
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20140010799 | HUMAN DIACYLGLYCEROL ACYLTRANSFERASE 2 (DGAT2) FAMILY MEMBERS AND USES THEREFOR - The present invention relates to compositions and methods for the diagnosis and treatment of obesity and related metabolic disorders. The invention provides isolated nucleic acids molecules, designated DGAT2 family member nucleic acid molecules, which encode diacylglycerol acyltransferase family members. The invention also provides recombinant expression vectors containing DGAT2 family member nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a DGAT2 family member gene has been introduced or disrupted. The invention still further provides isolated DGAT2 family member proteins, fusion proteins, antigenic peptides and anti-DGAT2 family member antibodies. Methods of use of the provided DGAT2 family member compositions for screening, diagnostic and therapeutic methods in connection with obesity disorders are also disclosed. | 01-09-2014 |
Rosana Kapeller-Libermann, Chesnut Hill, MA US
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20120115783 | PEPTIDOMIMETIC MACROCYCLES - The present invention provides novel peptidomimetic macrocycles and methods of using such macrocycles for the treatment of disease. | 05-10-2012 |
20120115793 | PEPTIDOMIMETIC MACROCYCLES - The present invention provides novel peptidomimetic macrocycles and methods of using such macrocycles for the treatment of disease. | 05-10-2012 |
Rosana Kapeller-Llbermann, Chestnut Hill, MA US
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20100216688 | PEPTIDOMIMETIC MACROCYCLES - The present invention provides biologically active crosslinked polypeptides with improved properties relative to their corresponding precursor polypeptides, having good cell penetration properties and reduced binding to human proteins. The invention additionally provides methods of identifying and making such improved polypeptides. | 08-26-2010 |
Rosana Kappeller-Libermann, Chestnut Hill, MA US
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20100136010 | Novel 27875, 22025, 27420, 17906, 16319, 55092 and 10218 molecules and uses therefor - The invention provides isolated nucleic acids molecules, designated 27875, 22025, 27420, 16319, 55092 and 10218 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 27875, 22025, 27420, 16319, 55092 and 10218 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 27875, 22025, 27420, 16319, 55092 and 10218 gene has been introduced or disrupted. The invention still further provides isolated 27875, 22025, 27420, 17906, 16319, 55092 or 10218 proteins, fusion proteins, antigenic peptides and anti-27875, 22025, 27420, 17906, 16319, 55092 or 10218 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided. | 06-03-2010 |
Rosana Rainho Das Neves, Sao Jose Dos Campos BR
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20110270209 | METHOD OF USING A DISPOSABLE SANITARY ABSORBENT ARTICLE ASSEMBLY INCLUDING AN INTEGRATED DISPOSAL SHEET - A method of using a disposing of a sanitary article assembly including a sanitary article and an integrated disposal sheet, the sanitary article assembly being structured and arranged to enable a user to manually separate the integrated disposal sheet from the article after the article has been soiled, roll the article from one end of the article to the opposite end of the article, and then enclose the article within the integrated disposal sheet by wrapping the integrated disposal sheet around the rolled article. | 11-03-2011 |
20110270210 | DISPOSABLE SANITARY ABSORBENT ARTICLE ASSEMBLY INCLUDING AN INTEGRATED DISPOSAL SHEET - A sanitary article assembly including a sanitary article and an integrated disposal sheet, the sanitary article assembly being structured and arranged to enable a user to manually separate the integrated disposal sheet from the article after the article has been soiled, roll the article from one end of the article to the opposite end of the article, and then enclose the article within the integrated disposal sheet by wrapping the integrated disposal sheet around the rolled article. | 11-03-2011 |
Rosana Sanchez-Lopez, Cuernavaca MX
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20130071399 | Immunogen and Antivenom Against Violin Spider Venom - The invention relates to the isolation, characterisation and expression of DNA fragments encoding sphingomyelinases D from three species of | 03-21-2013 |
Rosana Sanchez-Lopez, Morelos MX
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20110177078 | Immunogen and Antivenom Against Violin Spider Venom - The invention relates to the isolation, characterisation and expression of DNA fragments encoding sphingomyelinases D from three species of | 07-21-2011 |