Bembridge
Dawn Bembridge, Cambridge GB
Patent application number | Description | Published |
---|---|---|
20080213262 | Inhibition of Islet Amyloid Polypeptide (Iapp) Aggregation for the Treatment of Type 2 Diabetes - The present invention relates to the targeting and clearance of soluable unprocessed Islet Amyloid Polypeptide (hIAPP) in order to prevent the nucleation of hIAPP amyloidogenesis and to interfere with pancreatic cell death which is associated with the aggregation of hIAPP. Agents and methods for reducing hIAPP aggregation are provided herein and may be useful in the treatment of type 2 diabetes. | 09-04-2008 |
Dawn Ann Bembridge, Hertfordshire GB
Patent application number | Description | Published |
---|---|---|
20090175923 | HUMANIZED ANTI-AMYLOID BETA ANTIBODIES - Humanized anti-Aβ antibodies derived from a murine antibody directed to a N-terminal epitope of Aβ are described. The humanized antibodies have reduced or no human T cell epitopes and bind Aβ with an affinity similar to that of the murine antibody. | 07-09-2009 |
20110177076 | HUMANIZED ANTI-AMYLOID BETA ANTIBODIES - Humanized anti-Aβ antibodies derived from a murine antibody directed to a N-terminal epitope of Aβ are described. The humanized antibodies have reduced or no human T cell epitopes and bind Aβ with an affinity similar to that of the murine antibody. | 07-21-2011 |
Gary Bembridge, Herts GB
Patent application number | Description | Published |
---|---|---|
20100068226 | Polynucleotides and Uses Thereof - The present invention provides an isolated polynucleotide comprising or consisting of the nucleotide sequence encoding the G protein of human respiratory syncytial virus (RSV), wherein the nucleotide sequence is codon optimised for expression in mammalian cells and wherein the polynucleotide provides increased expression of the G protein in mammalian cells relative to expression of the wildtype RSV-G gene. Preferably, the polynucleotide comprises or consists of the nucleotide sequence of SEQ ID NO:2. Further aspects of the invention provide pharmaceutical compositions, in particular vaccines, for use in methods of immunising a subject against RSV infection. | 03-18-2010 |
Gary Peter Bembridge, Hertfordshire GB
Patent application number | Description | Published |
---|---|---|
20110206686 | IL-23 ANTIBODIES - The present invention relates to antigen binding proteins to human IL-23, pharmaceutical formulations containing them and to the use of such antigen binding proteins in the treatment and/or prophylaxis of inflammatory diseases such as Rheumatoid Arthritis (RA). | 08-25-2011 |
Gary Peter Bembridge, Stevenage GB
Patent application number | Description | Published |
---|---|---|
20090123479 | IMMUNOGLOBULINS - The present invention relates to antigen binding proteins to human IL-23, pharmaceutical formulations containing them and to the use of such antigen binding proteins in the treatment and/or prophylaxis of inflammatory diseases such as Rheumatoid Arthritis (RA). | 05-14-2009 |
20130251724 | ANTIGEN BINDING PROTEINS TO ONCOSTATIN M (OSM) - The present invention concerns antigen binding proteins and fragments thereof which specifically bind Oncostatin M (OSM), particularly human OSM (hOSM) and which inhibit the binding of OSM to the gp130 receptor but does not directly interact with site II residues. The invention also concerns a method of humanising antibodies. Further disclosed are pharmaceutical compositions, screening and medical treatment methods. | 09-26-2013 |
20150064201 | ANTIGEN BINDING PROTEINS TO ONCOSTATIN M (OSM) - The present invention concerns antigen binding proteins and fragments thereof which specifically bind Oncostatin M (OSM), particularly human OSM (hOSM) and which inhibit the binding of OSM to the gp130 receptor but does not directly interact with site II residues. The invention also concerns a method of humanising antibodies. Further disclosed are pharmaceutical compositions, screening and medical treatment methods. | 03-05-2015 |
Mathew L. Bembridge, Eindhoven NL
Patent application number | Description | Published |
---|---|---|
20100133982 | LAMP, LAMP HOLDER, AND ASSEMBLY OF SUCH A LAMP AND SUCH A LAMP HOLDER - The invention relates to an assembly of a lamp and a lamp holder. The invention also relates' to a lamp' for use in an assembly of a lamp and a lamp holder. The invention further relates to a lamp holder for use in an assembly of a lamp and a lamp holder. Assembly of a lamp ( | 06-03-2010 |
Mathew Lee Bembridge, Rotterdam NL
Patent application number | Description | Published |
---|---|---|
20120091903 | LUMINAIRE COMBINING AMBIENT LIGHT AND TASK LIGHT - A luminaire is disclosed that allows a transfer from ambient light to task light through physical manipulation by the user. The luminaire comprises OLED light sources for generating an ambient light effect and LED light sources for generating a task light effect. | 04-19-2012 |
20130120992 | LIGHTING MODULE AS A TOOL FOR CONNECTING/DISCONNECTING ANOTHER LIGHTING MODULE - A lighting module ( | 05-16-2013 |
20140128942 | DEVICE FOR LIGHT THERAPY WITH IMPROVED WEARING COMFORT - A light-emitting device is disclosed. The light-emitting device comprises a plurality of light-emitting elements or light sources and a flexible pad for position and conforming the light-emitting device to a portion of the body, wherein the flexible pad further comprises a three-dimensional structure having a plurality of protrusions for contacting the skin when the light-emitting device is applied to the skin, a plurality of recesses for creating a clearance between the skin and the flexible pad when the light-emitting device is applied to the skin, and a plurality of apertures for engaging with the plurality of light-emitting elements. | 05-08-2014 |
Mathew Lee Bembridge, Eindhoven NL
Patent application number | Description | Published |
---|---|---|
20080316747 | Luminaire with Louver Members - The invention relates to a reflector for a luminaire. The reflector comprises a cavity ( | 12-25-2008 |