Patent application number | Description | Published |
20100133104 | Fluid processing device including size-changing barrier - A diagnostic device is provided that includes a plurality of retainment regions interconnected through at least one fluid processing passageway or separated by at least one barrier. A fluid flow modulator can be provided in the fluid processing passageway if a fluid processing passageway is provided. The barrier and/or fluid flow modulator can comprise a polysaccharide, a derivative of a polysaccharide, or a combination thereof. For example, the barrier can comprise a chitosan material. | 06-03-2010 |
20100136701 | Device including a dissolvable structure for flow control - A diagnostic device is provided that includes a plurality of retainment regions, with the retainment regions that are separated by at least one dissolvable barrier. The retainment regions can be interconnected through at least one fluid processing passageway. A retainment region can include a container such as a retainment region, well, chamber, or other receptacle, or a retainment region such as a surface on which the material is retained. The retainment regions can include a reaction retainment region, one or more reagent retainment regions, each containing unreacted reagents, and a sample retainment region. A pressure-actuated valve can be positioned in each fluid processing passageway interconnecting the one or more reagent retainment regions with the respective intermediate retainment regions interposed between each of the one or more reagent retainment regions and the reaction retainment region. The dissolvable barrier can be a fluid flow modulator in the at least one fluid processing passageway. | 06-03-2010 |
20100261229 | SYSTEM AND METHOD FOR PREPARING AND USING BULK EMULSION - An emulsion generation apparatus and method for forming an emulsion are provided wherein a customized impeller design is adapted to form an emulsion with a desired droplet size that defines a desired volume. The emulsion generation apparatus provides improved uniformity in emulsion preparation and may be used to create large or small volume emulsions rapidly and reproducibly. A system and method are also provided for large volume sample amplification adaptable for use with conventional PCR-based reactions as well as emulsion-based PCR reactions and other reactions. For applications involving emulsion-based PCR amplification, the system and method provide improved uniformity in emulsion amplification and can be used to amplify large or small volume emulsions rapidly and reproducibly. | 10-14-2010 |
20110123985 | COLUMN ENRICHMENT OF PCR BEADS COMPRISING TETHERED AMPLICONS - An enrichment module and method are provided for enriching a population of templated beads and separating them from non-templated beads. The method can include hybridizing a templated bead with an enrichment bead to form a complex, trapping the complex in a filtration medium, washing non-templated beads through the filtration medium while retaining the complex, and then eluting the templated bead from the complex. The module can include a column for enrichment and filtration material exhibiting desired size-exclusion properties. | 05-26-2011 |
20110126913 | Device Including A Dissolvable Structure For Flow Control - A diagnostic device is provided that includes a plurality of retainment regions, with the retainment regions that are separated by at least one dissolvable barrier. The retainment regions can be interconnected through at least one fluid processing passageway. A retainment region can include a container such as a retainment region, well, chamber, or other receptacle, or a retainment region such as a surface on which the material is retained. The retainment regions can include a reaction retainment region, one or more reagent retainment regions, each containing unreacted reagents, and a sample retainment region. A pressure-actuated valve can be positioned in each fluid processing passageway interconnecting the one or more reagent retainment regions with the respective intermediate retainment regions interposed between each of the one or more reagent retainment regions and the reaction retainment region. The dissolvable barrier can be a fluid flow modulator in the at least one fluid processing passageway. | 06-02-2011 |
20130224877 | LUMINESCENCE REFERENCE STANDARDS - The present teachings provide for systems, and components thereof, for detecting and/or analyzing light. These systems can include, among others, optical reference standards utilizing luminophores, such as nanocrystals, for calibrating, validating, and/or monitoring light-detection systems, before, during, and/or after sample analysis. | 08-29-2013 |
20130231260 | POLYMER SCAFFOLDS FOR ASSAY APPLICATIONS - Reactive polymers bound to a solid support, modified solid supports and reactive polymers are provided. Solid supports comprising the same for use as analytical devices for the detection and/or characterization of analytes, such as biomolecules, are also provided. | 09-05-2013 |
20140106979 | POLYMERS HAVING ORTHOGONAL REACTIVE GROUPS AND USES THEREOF - Polymers having orthogonal reactive groups and solid supports comprising polymers immobilized thereto are provided. The polymers find utility in any number of applications including immobilizing analyte molecules to solid supports for high throughput assays. | 04-17-2014 |
20140284496 | LUMINESCENCE REFERENCE STANDARDS - The present teachings provide for systems, and components thereof, for detecting and/or analyzing light. These systems can include, among others, optical reference standards utilizing luminophores, such as nanocrystals, for calibrating, validating, and/or monitoring light-detection systems, before, during, and/or after sample analysis. | 09-25-2014 |
20140287945 | SURFACE OXIDATION FOR SEQUESTERING BIOMOLECULES AND RELATED METHODS - Solid supports comprising polymers covalently bound to a solid substrate are provided. The polymers find utility in any number of applications including immobilizing analyte molecules to solid supports for high throughput assays. | 09-25-2014 |
20150111200 | Luminescence Reference Standards - The present teachings provide for systems, and components thereof, for detecting and/or analyzing light. These systems can include, among others, optical reference standards utilizing luminophores, such as nanocrystals, for calibrating, validating, and/or monitoring light-detection systems, before, during, and/or after sample analysis. | 04-23-2015 |
Patent application number | Description | Published |
20100065052 | Heating Units - A heating unit comprises a substrate having a first surface and a second surface. A chemical reactant material capable of undergoing an exothermic reaction is disposed on at least a portion of the first surface of the substrate. An igniter is in proximity with the chemical reactant material. A layer of adhesive material overlays at least a portion of at least one of the chemical reactant material and the first surface of the substrate. Other embodiments of the heating unit include a first and a second substrate, each having first and second surfaces positioned with the first surfaces opposing each other in a sandwich construction. A chemical reactant material is disposed on at least a portion of the first surface of at least one of the substrates. The first and the second substrates are sealed together to define a cavity containing the chemical reactant material and an igniter is provided in proximity with the chemical reactant material. | 03-18-2010 |
20100068154 | Printable Igniters - An igniter comprises at least two conductors in the spaced-apart configuration and an electrically conductive layer bridging the at least two conductors, wherein the conductive layer has an electrical resistance greater than an electrical resistance of the at least two conductors. In one embodiment, the at least two conductors and the electrically conductive layer comprise a conductive ink, which may be the same conductive ink having different dimensions. A supplementary initiator composition may be deposited on or incorporated into the conductive layer. In a process for producing the igniter, the electrically conductive layer and the at least two conductors are printed on a non-electrically conducting substrate. Also disclosed are a method for igniting a combustible composition using the igniter, a method for producing an aerosol drug using the igniter, a method for providing a dose of a drug to a human patient using the igniter, a drug delivery device comprising the igniter and a drug supply unit comprising the igniter. | 03-18-2010 |
20100068155 | Reactant Formulations and Methods for Controlled Heating - Disclosed herein are reactant formulations capable of undergoing an exothermic chemical reaction. The reactant formulations comprise a metal reducing agent, a metal-containing oxidizing agent, and manganese oxide in an amount effective to control a temperature profile of the reactant formulation. The manganese oxide may be, for example and without limitation, MnO, MnO | 03-18-2010 |