Patent application number | Description | Published |
20110093220 | INTEGRATED ACOUSTIC LEAK DETECTION SYSTEM USING INTRUSIVE AND NON-INTRUSIVE SENSORS - A system for detecting and locating leaks includes a pipeline, strain sensors positioned on the external surface of the pipeline, acoustic pressure sensors positioned at intervals along the pipeline, local processors connected to the strain sensors and acoustic pressure sensors, and a central processor connected to the local processors. The strain sensors measure a strain on the external surface of the pipeline indicative of changes in the pressure of the fluid within the pipeline. The acoustic pressure sensors sense acoustic signals within the pipline. Sensed acoustic pressure signals and sensed strain measurements are compared to each other and to stored profiles to detect and locate leaks. | 04-21-2011 |
20110114119 | SCRAPER TRACKING SYSTEM - A tracking system for use with a pipeline includes a scraper having signal generation capability for generating acoustic signals, a plurality of acoustic pressure sensors positioned at intervals along the path travelled by the scraper, and a plurality of local processors positioned at intervals along the path travelled by the scraper. Each of the local processors is in communication with a respective acoustic pressure sensor. A central processor is in communication with the local processors and determines the location of the scraper using time-stamped acoustic signals received by the pressure sensors and a speed of sound in a fluid within the pipeline. | 05-19-2011 |
20130276250 | Trackable pipeline scraper for active tracking and locating - A tracking system for use with a pipeline includes a scraper having signal generation capability for generating acoustic signals, a plurality of acoustic pressure sensors positioned at intervals along the path traveled by the scraper, and a plurality of local processors positioned at intervals along the path traveled by the scraper. Each of the local processors is m communication with a respective acoustic pressure sensor. A central processor is in communication with the local processors and determines the location of the scraper using time-stamped acoustic signals received by the pressure sensors and a speed of sound, in a fluid within the pipeline. | 10-24-2013 |
20130279296 | TRACKING SYSTEM FOR A PIPELINE - A tracking system for use with a pipeline includes a scraper having signal generation capability for generating acoustic signals, a plurality of acoustic pressure sensors positioned at intervals along the path traveled by the scraper, and a plurality of local processors positioned at intervals along the path traveled by the scraper. Each of the local processors is in communication with a respective acoustic pressure sensor. A central processor is in communication with the local processors and determines the location of the scraper using time-stamped acoustic signals received by the pressure sensors and a speed of sound in a fluid within the pipeline. | 10-24-2013 |
Patent application number | Description | Published |
20090111803 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS - This invention relates to compounds of the Formula (I): | 04-30-2009 |
20090137586 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS - This invention relates to compounds of the Formula (I): | 05-28-2009 |
20090156586 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS - This invention relates to compounds of the Formula (I): | 06-18-2009 |
20090170875 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS - This invention relates to compounds of the Formula (I): | 07-02-2009 |
20100120838 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS - This invention relates to compounds of the Formula (I): | 05-13-2010 |
20110178007 | SPIRO-IMIDAZOLONE DERIVATIVES AS GLUCAGON RECEPTOR ANTAGONISTS - The present invention relates to compounds of the general formula: (I) wherein ring A, ring B, R | 07-21-2011 |
20110288054 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS - This invention relates to compounds of the Formula (I) as described herein, or a pharmaceutically acceptable salt, solvate or ester thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof. | 11-24-2011 |
20110288077 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES - This invention relates to compounds of the Formula (I)-(IX):, as defined herein, or a pharmaceutically acceptable salt, solvate or ester thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF-α combinations thereof. | 11-24-2011 |
20120010181 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS - This invention relates to compounds of the Formula (I): (Chemical formula should be inserted here as it appears on abstract in paper form) (I) or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF—or combinations thereof. | 01-12-2012 |
20120015926 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS - This invention relates to compounds of the Formula (I): (Chemical formula should be inserted here as it appears on abstract in paper form) (I) or a pharmaceutically acceptable salt thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof. | 01-19-2012 |
20130012434 | NOVEL SPIRO IMIDAZOLONES AS GLUCAGON RECEPTOR ANTAGONISTS, COMPOSITIONS, AND METHODS FOR THEIR USE - The present invention relates to compounds of the general formula: wherein ring A, ring B, R1, R3, Z, L1, and L2 are selected independently of each other and are as defined herein, to compositions comprising the compounds, and to methods of using the compounds as glucagon receptor antagonists and for the treatment or prevention of type 2 diabetes and conditions related thereto. | 01-10-2013 |
Patent application number | Description | Published |
20100174064 | FORMS OF RIFAXIMIN AND USES THEREOF - The present invention relates to Rifaximin polymorphic forms, to their use in medicinal preparations and to therapeutic methods using them. | 07-08-2010 |
20100239664 | FORMS OF RIFAXIMIN AND USES THEREOF - The present invention relates to Rifaximin polymorphic, salt, hydrate, and amorphous forms, to their use in medicinal preparations and to therapeutic methods using them. | 09-23-2010 |
20110053997 | Salts and Crystal Forms - The present invention relates to novel salts of the compound (R)-5-(2-Aminoethyl)-1-(6,8-difluorochroman-3-yl)-1,3-dihydroimidazole-2-thione, polymorphs of the salts and methods of their preparation. | 03-03-2011 |
20120076857 | FORMS OF RIFAXIMIN AND USES THEREOF - The present invention relates to Rifaximin polymorphic, salt, hydrate, and amorphous forms, to their use in medicinal preparations and to therapeutic methods using them. | 03-29-2012 |
20120316334 | FORMS OF RIFAXIMIN AND USES THEREOF - The present invention relates to Rifaximin polymorphic forms, to their use in medicinal preparations and to therapeutic methods using them. | 12-13-2012 |
20130066079 | FORMS OF RIFAXIMIN AND USES THEREOF - The present invention relates to Rifaximin polymorphic, salt, hydrate, and amorphous forms, to their use in medicinal preparations and to therapeutic methods using them. | 03-14-2013 |
20140011828 | FORMS OF RIFAXIMIN AND USES THEREOF - The present invention relates to Rifaximin amorphous forms, to their use in medicinal preparations and to therapeutic methods using them. | 01-09-2014 |
20140141081 | FORMS OF RIFAXIMIN AND USES THEREOF - The present invention relates to Rifaximin polymorphic, salt, hydrate, and amorphous forms, to their use in medicinal preparations and to therapeutic methods using them. | 05-22-2014 |
20140179916 | FORMS OF RIFAXIMIN AND USES THEREOF - The present invention relates to Rifaximin polymorphic forms, to their use in medicinal preparations and to therapeutic methods using them. | 06-26-2014 |
Patent application number | Description | Published |
20110093220 | INTEGRATED ACOUSTIC LEAK DETECTION SYSTEM USING INTRUSIVE AND NON-INTRUSIVE SENSORS - A system for detecting and locating leaks includes a pipeline, strain sensors positioned on the external surface of the pipeline, acoustic pressure sensors positioned at intervals along the pipeline, local processors connected to the strain sensors and acoustic pressure sensors, and a central processor connected to the local processors. The strain sensors measure a strain on the external surface of the pipeline indicative of changes in the pressure of the fluid within the pipeline. The acoustic pressure sensors sense acoustic signals within the pipline. Sensed acoustic pressure signals and sensed strain measurements are compared to each other and to stored profiles to detect and locate leaks. | 04-21-2011 |
20110114119 | SCRAPER TRACKING SYSTEM - A tracking system for use with a pipeline includes a scraper having signal generation capability for generating acoustic signals, a plurality of acoustic pressure sensors positioned at intervals along the path travelled by the scraper, and a plurality of local processors positioned at intervals along the path travelled by the scraper. Each of the local processors is in communication with a respective acoustic pressure sensor. A central processor is in communication with the local processors and determines the location of the scraper using time-stamped acoustic signals received by the pressure sensors and a speed of sound in a fluid within the pipeline. | 05-19-2011 |
20130276250 | Trackable pipeline scraper for active tracking and locating - A tracking system for use with a pipeline includes a scraper having signal generation capability for generating acoustic signals, a plurality of acoustic pressure sensors positioned at intervals along the path traveled by the scraper, and a plurality of local processors positioned at intervals along the path traveled by the scraper. Each of the local processors is m communication with a respective acoustic pressure sensor. A central processor is in communication with the local processors and determines the location of the scraper using time-stamped acoustic signals received by the pressure sensors and a speed of sound, in a fluid within the pipeline. | 10-24-2013 |
20130279296 | TRACKING SYSTEM FOR A PIPELINE - A tracking system for use with a pipeline includes a scraper having signal generation capability for generating acoustic signals, a plurality of acoustic pressure sensors positioned at intervals along the path traveled by the scraper, and a plurality of local processors positioned at intervals along the path traveled by the scraper. Each of the local processors is in communication with a respective acoustic pressure sensor. A central processor is in communication with the local processors and determines the location of the scraper using time-stamped acoustic signals received by the pressure sensors and a speed of sound in a fluid within the pipeline. | 10-24-2013 |
Patent application number | Description | Published |
20100243472 | HIGH-THROUGHPUT LOCAL OXIDATION NANOLITHOGRAPHIC PROCESS - In a lithographic process suitable for use in the manufacture of electronic components, oxidative reactions are employed to reproducibly fabricate patterns having micro- or nano-scale dimensions. An electrically-conductive template is fabricated to have a nanometer-scale sharp edge and describe a pattern having a micron-scale length. The oxidative reaction is mediated by a water meniscus connecting the sharp edge of the template and an oxidizable substrate. One suitable substrate is graphene. The template can be controllably positioned using a light lever method. | 09-30-2010 |
20110140088 | PHASE COHERENT SOLID STATE ELECTRON GYROSCOPE ARRAY - An apparatus and method is disclosed which may comprise an electron gyroscope, which may comprise an interferometer array which may comprise interferometer rings formed from a sheet of graphene. Each interferometer ring in the interferometer array may have a half-circumference shorter in length than the ballistic length for an electron in graphene. | 06-16-2011 |
20120153119 | ACTIVE BANDGAP TUNING OF GRAPHENE FOR TUNABLE PHOTODETECTION APPLICATIONS - In a method for adjusting the sensitivity of a photodetector, the bandgap of the photodetection material is adjusted by inducing strain in the photodetection material. Such adjustments can be made in situ and continuously, in a reproducible and repeatable manner. In embodiments of the method, the photodetection material is graphene, carbon nanotubes or graphene nanoribbon. The use of graphene permits a dynamically-adjustable sensitivity over a dynamic range of radiation having wavelengths of 1.38 microns or less, up to at least 60 microns. In an adjustable photodetector, a graphene layer is suspended over a silicon substrate by a layer of an insulating material. Adjusting the voltage across the graphene layer and the silicon substrate induces strain in the graphene layer by electrostatic attraction. | 06-21-2012 |
20120248229 | MARANGONI STRESS-DRIVEN DROPLET MANIPULATION ON SMART POLYMERS FOR ULTRA-LOW VOLTAGE DIGITAL MICROFLUIDICS - An ultra-low voltage microfluidic device for manipulating droplets of liquid by inducing Marangoni stress therein includes a plurality of smart-polymer electrodes having films of smart polymer exposed at their surfaces. The surface of the smart polymer becomes hydrophobic or hydrophilic in response to different electromagnetic potentials. The smart polymer is reversibly oxidized by applying an electrical potential such that the smart polymer acquires a positive electrical charge. The oxidized smart polymer is reduced by applying an electrical potential such that it loses its positive electrical charge. The smart polymer is doped with a chemical compound having a negatively-charged end and a long-chain hydrophobic tail. The smart polymer is a polypyrrole and the dopant is a dodecylbenzene sulfonate. The microfluidic device includes a plurality of individually-addressable control electrodes, each of which is electrically-connected with smart-polymer electrodes. Droplets are transported, cut, or mixed by selectively applying electrical potential to individual electrodes. | 10-04-2012 |
20140231002 | HIGH-THROUGHPUT GRAPHENE PRINTING AND SELECTIVE TRANSFER USING A LOCALIZED LASER HEATING TECHNIQUE - A method of high-throughput printing and selective transfer of graphene onto a substrate includes the steps of: providing a thermal release tape having graphene adhered thereto; placing a substrate onto the graphene; pressing the thermal tape and the graphene against the substrate at a uniformly-distributed pressure; heating localized portions of the thermal tape and graphene using a localized heat source, thereby diminishing the adhesive properties of the thermal release tape in the localized portions and transferring graphene from said localized portions to the substrate; and separating the thermal release tape from the substrate. The method may include the further step of moving the localized heat source to selected positions on the thermal release tape during the heating step, thereby forming a pattern of heated portions. The method may use a laser beam as the localized heat source, movement of the laser beam being performed by a computer-controlled deflectable mirror. | 08-21-2014 |
Patent application number | Description | Published |
20090325953 | P38 KINASE INHIBITING AGENTS - Compounds described by the chemical formula (I) or pharmaceutically acceptable salts thereof: | 12-31-2009 |
20110105430 | PYRROLO [2,3-C] PYRIDINE DERIVATIVES AS P38 KINEASE INHIBITING AGENTS - Compounds described by the chemical formula (I) or pharmaceutically acceptable salts thereof: (A) are inhibitors N of p38 and are useful in the treatment of inflammation such as in the treatment of asthma, rheumatoid arthritis, rheumatoid spondylitis, osteoarthritis, gouty arthritis and other arthritic conditions; inflamed joints, eczema, psoriasis or other inflammatory skin conditions such as sunburn; inflammatory eye conditions including conjunctivitis; pyresis, pain and other conditions associated with inflammation. | 05-05-2011 |
20120040999 | P38 KINASE INHIBITING AGENTS - Compounds described by the chemical formula (I) or pharmaceutically acceptable salts thereof: Formula (I); are inhibitors of p38 and are useful in the treatment of inflammation such as in the treatment of asthma, COPD, ARDS, rheumatoid arthritis, rheumatoid spondylitis, osteoarthritis, gouty arthritis and other arthritic conditions; inflamed joints, eczema, psoriasis or other inflammatory skin conditions such as sunburn; inflammatory eye conditions including conjunctivitis; pyresis, pain and other conditions associated with inflammation. | 02-16-2012 |
Patent application number | Description | Published |
20090111873 | Novel Zeta-Cypermethrin Composition - The present invention is directed to an insecticidal composition comprising zeta-cypermethrin: a) prepared by an epimerization process, and b) containing a residual amount of an epimerization catalyst, and glycerine, wherein the zeta-cypermethrin is present in an insecticidally effective amount and to methods of using the composition. | 04-30-2009 |
20090131518 | Insecticidal and Miticidal Mixtures of Bifenthrin and Cyano-Pyrethroids - The present invention is directed to novel insecticidal and/or miticidal compositions comprising bifenthrin and a cyano-pyrethroid. The compositions exhibit an unexpected increase in insecticidal activity as compared to the insecticidal activity of the individual components. | 05-21-2009 |
20090170935 | Novel Formulations of Bifenthrin and Enriched Cypermethrin - The present invention is directed to novel insecticidal compositions comprising bifenthrin and enriched cypermethrin, the compositions are physically stable when diluted with water. | 07-02-2009 |
20120172428 | Novel Formulations of Bifenthrin and Enriched Cypermethrin - The present invention is directed to novel insecticidal compositions comprising bifenthrin and enriched cypermethrin, the compositions are physically stable when diluted with water. | 07-05-2012 |
20120302742 | PROCESS FOR ISOLATING FUCOIDAN AND LAMINARIN FROM LIVE, HARVESTED SEAWEED - The present invention is directed to a process for obtaining at least one of fucoidan and laminarin from live, harvested seaweed, wherein the process comprises the steps of: (i) harvesting seaweed comprising fucoidan and laminarin to obtain live, harvested seaweed, wherein the live, harvested seaweed exudes to form an exudate solution; (ii) collecting the exudate solution from the live, harvested seaweed, wherein the fucoidan and laminarin are dissolved in the exudate solution; and (iii) separating the at least one of fucoidan or laminarin from the exudate solution. | 11-29-2012 |
20130012578 | Novel Formulations of Bifenthrin and Enriched Cypermethrin - The present invention is directed to novel insecticidal compositions comprising bifenthrin and enriched cypermethrin, the compositions are physically stable when diluted with water. | 01-10-2013 |
Patent application number | Description | Published |
20100273683 | Compositions having hase rheology modifiers - A monomer compound that contains at least one polymerizable functional group per molecule, and at least one bicycloheptyl-, bicycloheptenyl-, or branched (C | 10-28-2010 |
20120116005 | Compositions having hase rheology modifiers - A monomer compound that contains at least one polymerizable functional group per molecule, and at least one bicycloheptyl-, bicycloheptenyl-, or branched (C | 05-10-2012 |
20120116040 | Compositions having HASE rheology modifiers - A monomer compound that contains at least one polymerizable functional group per molecule, and at least one bicycloheptyl-, bicycloheptenyl-, or branched (C | 05-10-2012 |
20120121523 | Compositions having hase rheology modifiers - A monomer compound that contains at least one polymerizable functional group per molecule, and at least one bicycloheptyl-, bicycloheptenyl-, or branched (C | 05-17-2012 |
20120123149 | Composition having hase rheology modifiers - A monomer compound that contains at least one polymerizable functional group per molecule, and at least one bicycloheptyl-, bicycloheptenyl-, or branched (C | 05-17-2012 |
20130129647 | Compositions Having Hase Rheology Modifiers - A monomer compound that contains at least one polymerizable functional group per molecule, and at least one bicycloheptyl-, bicycloheptenyl-, or branched (C | 05-23-2013 |
20130296516 | Compositions Having HASE Rheology Modifiers - A monomer compound that contains at least one polymerizable functional group per molecule, and at least one bicycloheptyl-, bicycloheptenyl-, or branched (C | 11-07-2013 |
20140099276 | Compositions Having Hase Rheology Modifiers - A monomer compound that contains at least one polymerizable functional group per molecule, and at least one bicycloheptyl-, bicycloheptenyl-, or branched (C | 04-10-2014 |
Patent application number | Description | Published |
20090094631 | SYSTEMS, APPARATUS AND METHODS TO ASSOCIATE RELATED MARKET BROADCAST DETECTIONS WITH A MULTI-MARKET MEDIA BROADCAST - Systems, apparatus and methods to associate related market broadcast detections with a multi-market media broadcast are disclosed. An example disclosed method comprises obtaining a plurality of broadcast detection records, each broadcast detection record comprising detection information obtained by detecting an instance of a broadcast item in a broadcast market, comparing the plurality of broadcast detection records using first association criteria to identify a first group of broadcast detection records from the plurality of broadcast detection records, comparing the plurality of broadcast detection records using second association criteria to identify a second group of broadcast detection records from the plurality of broadcast detection records, the second association criteria different from the first association criteria, and determining a third group of broadcast detection records from the plurality of broadcast detection records to associate with a multi-market media broadcast, the third group corresponding to a larger of the first and the second group. | 04-09-2009 |
20090187932 | METHODS AND APPARATUS TO MONITOR, VERIFY, AND RATE THE PERFORMANCE OF AIRINGS OF COMMERCIALS - Methods and apparatus to monitor, verify, and rate the performance of airings of commercials are disclosed. An example method includes receiving an identification of an advertisement that was presented on a media presentation channel at a time, receiving ratings information for the media presentation channel associated with the time period, identifying a buy order for the received identification, receiving a purchased ratings value associated with the buy order, comparing the purchased ratings value to the ratings information, and displaying an indication of whether the ratings information is less than the purchased ratings value. | 07-23-2009 |
20140114751 | METHODS AND APPARATUS TO MONITOR, VERIFY, AND RATE THE PERFORMANCE OF AIRINGS OF COMMERCIALS - Methods and apparatus to monitor, verify, and rate the performance of airings of commercials are disclosed. An example method includes analyzing received advertisement detection information associated with the advertisement, the advertisement detection information detected from a presentation of the advertisement; identifying a buy order corresponding to the presentation of the advertisement based on the advertisement detection information; determining a purchased ratings value from the buy order; comparing the purchased ratings value of the buy order to received ratings information corresponding to the presentation of the advertisement to determine whether the advertisement was presented as indicated in the buy order; and generating a performance monitoring report using the buy order and the advertisement detection information to indicate whether the ratings information is less than the purchased ratings value. | 04-24-2014 |
Patent application number | Description | Published |
20090253179 | Mammalian Cell Lines for Increasing Longevity and Protein Yield from a Cell Culture - Disclosed are compositions and methods for increasing the longevity of a cell culture and permitting the increased production of proteins, preferably recombinant proteins, such as antibodies, peptides, enzymes, growth factors, interleukins, interferons, hormones, and vaccines. Cells transfected with an apoptosis-inhibiting gene or vector, such as a triple mutant Bcl-2 gene, can survive longer in culture, resulting in extension of the state and yield of protein biosynthesis. Such transfected cells exhibit maximal cell densities that equal or exceed the maximal density achieved by the parent cell lines. Transfected cells can also be pre-adapted for growth in serum-free medium, greatly decreasing the time required to obtain protein production in serum-free medium. In certain methods, the pre-adapted cells can be used for protein production following transformation under serum-free conditions. The method preferably involves eukaryotic cells, more preferably mammalian cells. | 10-08-2009 |
20100311162 | Mammalian Cell Lines for Increasing Longevity and Protein Yield from a Cell Culture - Disclosed are compositions and methods for increasing the longevity of a cell culture and permitting the increased production of proteins, preferably recombinant proteins, such as antibodies, peptides, enzymes, growth factors, interleukins, interferons, hormones, and vaccines. Cells transfected with an apoptosis-inhibiting gene or vector, such as a triple mutant Bcl-2 gene, can survive longer in culture, resulting in extension of the state and yield of protein biosynthesis. Such transfected cells exhibit maximal cell densities that equal or exceed the maximal density achieved by the parent cell lines. Transfected cells can also be pre-adapted for growth in serum-free medium, greatly decreasing the time required to obtain protein production in serum-free medium. In certain methods, the pre-adapted cells can be used for protein production following transformation under serum-free conditions. The method preferably involves eukaryotic cells, more preferably mammalian cells. | 12-09-2010 |
20120088299 | Mammalian Cell Lines for Increasing Longevity and Protein Yield from a Cell Culture - Disclosed are compositions and methods for increasing the longevity of a cell culture and permitting the increased production of proteins, preferably recombinant proteins, such as antibodies, peptides, enzymes, growth factors, interleukins, interferons, hamiones, and vaccines. Cells transfected with an apoptosis-inhibiting gene or vector, such as a triple mutant Bcl-2 gene, can survive longer in culture, resulting in extension of the state and yield of protein biosynthesis. Such transfected cells exhibit maximal cell densities that equal or exceed the maximal density achieved by the parent cell lines. Transfected cells can also be pre-adapted for growth in serum-free medium, greatly decreasing the time required to obtain protein production in serum-free medium. In certain methods, the pre-adapted cells can be used for protein production following transformation under serum-free conditions. The method preferably involves eukaryotic cells, more preferably mammalian cells. | 04-12-2012 |
20120196326 | Mammalian Cell Lines for Increasing Longevity and Protein Yield from a Cell Culture - Disclosed are compositions and methods for increasing the longevity of a cell culture and permitting the increased production of proteins, preferably recombinant proteins, such as antibodies, peptides, enzymes, growth factors, interleukins, interferons, hormones, and vaccines. Cells transfected with an apoptosis-inhibiting gene or vector, such as a triple mutant Bcl-2 gene, can survive longer in culture, resulting in extension of the state and yield of protein biosynthesis. Such transfected cells exhibit maximal cell densities that equal or exceed the maximal density achieved by the parent cell lines. Transfected cells can also be pre-adapted for growth in serum-free medium, greatly decreasing the time required to obtain protein production in serum-free medium. In certain methods, the pre-adapted cells can be used for protein production following transformation under serum-free conditions. The method preferably involves eukaryotic cells, more preferably mammalian cells. | 08-02-2012 |
20130164783 | Mammalian Cell Lines for Increasing Longevity and Protein Yield from a Cell Culture - Disclosed are compositions and methods for increasing the longevity of a cell culture and permitting the increased production of proteins, preferably recombinant proteins, such as antibodies, peptides, enzymes, growth factors, interleukins, interferons, hormones, and vaccines. Cells transfected with an apoptosis-inhibiting gene or vector, such as a triple mutant Bcl-2 gene, can survive longer in culture, resulting in extension of the state and yield of protein biosynthesis. Such transfected cells exhibit maximal cell densities that equal or exceed the maximal density achieved by the parent cell lines. Transfected cells can also be pre-adapted for growth in serum-free medium, greatly decreasing the time required to obtain protein production in serum-free medium. In certain methods, the pre-adapted cells can be used for protein production following transformation under serum-free conditions. The method preferably involves eukaryotic cells, more preferably mammalian cells. | 06-27-2013 |
20140038284 | Mammalian Cell Lines for Increasing Longevity and Protein Yield from a Cell Culture - Disclosed are compositions and methods for increasing the longevity of a cell culture and permitting the increased production of proteins, preferably recombinant proteins, such as antibodies, peptides, enzymes, growth factors, interleukins, interferons, hormones, and vaccines. Cells transfected with an apoptosis-inhibiting gene or vector, such as a triple mutant Bcl-2 gene, can survive longer in culture, resulting in extension of the state and yield of protein biosynthesis. Such transfected cells exhibit maximal cell densities that equal or exceed the maximal density achieved by the parent cell lines. Transfected cells can also be pre-adapted for growth in serum-free medium, greatly decreasing the time required to obtain protein production in serum-free medium. In certain methods, the pre-adapted cells can be used for protein production following transformation under serum-free conditions. The method preferably involves eukaryotic cells, more preferably mammalian cells. | 02-06-2014 |
20140308703 | Mammalian Cell Lines for Increasing Longevity and Protein Yield from a Cell Culture - Disclosed are compositions and methods for increasing the longevity of a cell culture and permitting the increased production of proteins, preferably recombinant proteins, such as antibodies, peptides, enzymes, growth factors, interleukins, interferons, hormones, and vaccines. Cells transfected with an apoptosis-inhibiting gene or vector, such as a triple mutant Bcl-2 gene, can survive longer in culture, resulting in extension of the state and yield of protein biosynthesis. Such transfected cells exhibit maximal cell densities that equal or exceed the maximal density achieved by the parent cell lines. Transfected cells can also be pre-adapted for growth in serum-free medium, greatly decreasing the time required to obtain protein production in serum-free medium. In certain methods, the pre-adapted cells can be used for protein production following transformation under serum-free conditions. The method preferably involves eukaryotic cells, more preferably mammalian cells. | 10-16-2014 |
Patent application number | Description | Published |
20110002381 | BITRATE CONTROL ALGORITHM FOR VIDEO TRANSCODING SYSTEMS - A video transcoding system and method employing an improved rate control algorithm. A plurality of frames in an input video bitstream are received by the system, in which each frame is in a first coding format. Each frame in the input bitstream is decoded, and complexity information indicating the complexity of the frame after decoding is obtained. An estimated number of bits to allocate for the respective frame is calculated. Using a rate estimation model that employs the complexity information for the respective frame, a picture cost for the frame is calculated based on the estimated number of bits allocated to encode the frame, and a parameter of the rate estimation model. A target cost for the respective frame is calculated based at least in part on the picture cost 10 and the complexity information for the frame. A quantization parameter (QP) is calculated that, when used to encode the respective frame in a second coding format, would generate an encoded frame having an actual cost approximately equal to the target cost. The respective frame is encoded using the calculated QP, and the frames encoded in the second coding format are provided in an output video bitstream. | 01-06-2011 |
20120069896 | EFFICIENT CODING COMPLEXITY ESTIMATION FOR VIDEO TRANSCODING SYSTEMS - Systems and methods of transcoding video bitstreams that employ highly efficient look-ahead approaches to video transcoding. The systems and methods perform video transcoding in the pixel domain to make successive adjustments to estimates of the coding complexity of video frames in input video bitstreams. The systems and methods can employ the adjusted estimates of the coding complexity in a rate control function to provide improved bit allocations for the video frames in transcoded output video bitstreams, thereby enhancing overall perceptual quality. | 03-22-2012 |
20120257672 | PERCEPTUAL PROCESSING TECHNIQUES FOR VIDEO TRANSCODING - Systems and methods of video transcoding that employ perceptual processing techniques for enhancing the perceptual quality of transcoded video information, communications, entertainment, and other video content. Such systems and methods of video transcoding are operative to perform perceptual processing of an input video bitstream using predetermined information carried by the input bitstream. Having performed such perceptual processing of the input bitstream, the perceptual quality of transcoded video delivered to an end user is significantly improved. | 10-11-2012 |
20120269258 | RATE CONTROL WITH LOOK-AHEAD FOR VIDEO TRANSCODING - Systems and methods of transcoding video bitstreams that employ look-ahead approaches to enhance the overall perceptual quality of transcoded video information, communications, and entertainment delivered to an end user. The disclosed systems and methods of transcoding video bitstreams take into account the scene characteristics and the local coding complexity of video frames in a video sequence before performing bit allocations for the video frames, thereby significantly improving the perceptual quality of transcoded video delivered to the end user. | 10-25-2012 |
Patent application number | Description | Published |
20080279466 | Methods and Systems for Rate-Distortion Optimized Quantization of Transform Blocks in Block Transform Video Coding - Provided are methods and systems for rate-distortion optimized quantization and for skipping transform blocks that can take into account the rate-distortion tradeoff as well as the perceptual quality of reconstructed video. | 11-13-2008 |
20140375756 | RESOURCE-ADAPTIVE VIDEO ENCODER SHARING IN MULTIPOINT CONTROL UNIT - Systems and methods of video conferencing, in which existing video encoders associated with a multipoint control unit (MCU) can be shared among conference participant devices, depending upon the availability of processor and/or memory resources for the MCU. In making decisions regarding the sharing of video encoders, the systems and methods take into account various parameters associated with potential conference participant devices and the total cost of the processor/memory resources for the MCU, to determine whether a video encoder of the MCU can be shared with, or allocated to, the respective conference participant devices. By determining whether to share or allocate a video encoder of the MCU, depending upon the available processor/memory resources for the MCU, the MCU can be made to operate with increased stability. The systems and methods can be applied to any application that sends the same content to multiple receivers, including announcement and video streaming applications. | 12-25-2014 |
20140376617 | RATE CONTROL ALGORITHM FOR SCALABLE VIDEO ENCODING WITH DISPOSABLE P-FRAMES - Systems and methods of performing rate control in scalable video encoders that can be used to provide videoconferencing, announcements, and live video streaming to multiple participant devices having diverse bandwidths, resolutions, and/or other device characteristics. The systems and methods can accommodate different target bit rates of the multiple participant devices by operating on scalable video bitstreams in a multi-layer video format, including a base layer having one or more reference video frames, and an enhancement layer having one or more disposable non-reference, predictive video frames. By adjusting the number of disposable non-reference, predictive video frames in the enhancement layer, as well as quantization parameters for the respective base and enhancement layers, the disclosed systems and methods can accommodate the different target bit rates for the respective participant devices, while enhancing the spatial and/or temporal qualities of the base and enhancement layers in the respective video bitstreams. | 12-25-2014 |
20140376632 | Application-Assisted Spatio-Temporal Error Concealment for RTP Video - Systems and methods that employ an application-assisted approach to adaptive spatio-temporal error concealment in video decoders. The systems and methods employ a video receiver that can receive real-time video frames from a video transmitter over a wired and/or wireless network. The video receiver includes an end system configurable as an application for consuming the content of the real-time video frames. The end system application can determine whether each received real-time video frame is complete or incomplete, whether each received slice is complete or incomplete, and provide such information to the video decoder for use in avoiding errors while decoding the respective real-time video frames. The video decoder can determine whether any pixel blocks included in real-time video packets are properly decoded or missing, generate statistics regarding the coding mode of the respective pixel blocks, and use such further information while performing adaptive spatio-temporal error concealment on the respective pixel blocks. | 12-25-2014 |
Patent application number | Description | Published |
20090027382 | Method and system for direct rendering of multi-volume data - A method for performing direct rendering of a multi-volume data, having the steps of determining whether a volume of the multi-volume data is one of active and inactive via interaction with a ray for the multi-volume data, recording in triplicate a starting point and an end point of the ray for an eyespace, repeating the determining whether the volume is one of active and inactive via interaction with a ray for the multi-volume data and the recording in triplicate a starting point and an end point of the ray for an eyespace for all volumes of the multi-volume data, providing triples from all volumes to an array, sorting the array to create a sorted triples list array, breaking the ray into a plurality of segments using the sorted triples list array, determining which volumes are active for each of the segments via an active volume list, and sampling each segment of the ray to acquire an accumulated result. | 01-29-2009 |
20130002673 | Volume Rendering Using N-Pass Sampling - A system and method for increasing resolution of an object and increasing rendering speed by rendering with a lesser density for non-object regions. The system and method includes sampling a plurality of first rays in a first density through a volume, each first ray being in a separate section, if a sampling value difference of at least two first rays is above a first threshold, sampling a plurality of second rays in a second density, the second rays being in a first section of the separate sections, the first section being for one of the at least two first rays, and if a sampling value difference between a first one of the second rays and another ray is above a second threshold, sampling a plurality of third rays in a second section spatially different than the first section, the sampling of the third rays being at the second spatial density and the second section being a neighboring section to the first section. | 01-03-2013 |
20130208989 | SYSTEM AND METHOD FOR SHAPE MEASUREMENTS ON THICK MPR IMAGES - A method for measuring shapes in thick multi-planar reformatted (MPR) digital images, including identifying a shape in a digital MPR image, scan-converting points corresponding to the identified shape on a starting plane of an MPR slab in an image volume from which the MPR was obtained to generate a plurality of starting points for the identified shape, calculating an end point in the MPR slab corresponding to each starting point, propagating a ray from each starting point to each corresponding end point, accumulating samples along each ray, and computing a desired measurement value from the accumulated samples after reaching the end point for all rays. | 08-15-2013 |
Patent application number | Description | Published |
20090023847 | Degassing compositions for curable coatings - Non-yellowing degassing compositions which enhance degassing in powder coatings and other film-forming curable coatings are disclosed. The non-yellowing compositions contain degassing agents including a plurality of unfused aromatic rings and at least one functional group selected from ketals, carbamates, carbonates and carboxylic acid esters. The degassing agents resist decomposition and discoloration, and are relatively stable at resin curing conditions and. The degassing agents may be synergistically combined with other materials, such as fatty acid amide-containing waxes, to produce new and surprisingly effective degassing compositions suitable for use in powder coatings. Curable compositions which utilize the new degassing compositions are also disclosed. | 01-22-2009 |
20100003345 | Synergistic antimicrobial mixtures - A broad spectrum antimicrobial composition comprising a mixture of an iodopropynyl compound in combination with a benzimidazole and a metal borate is disclosed. The composition can be used to protect industrial systems against microbial growth and, more particularly, to protect substrates such as paints, coatings, stucco, concrete, stone, cementaceous surfaces, wood, wood-plastic composites, caulking, sealants, textiles, leather, wood, preservatives, metal working fluids, drilling muds, clay slurries, glazes, optical brighteners, carpet backing, and pigments against microbial growth. The composition can be used as a preservative for aqueous products. | 01-07-2010 |
20100204373 | Degassing compositions for curable coatings - Non-yellowing degassing compositions which enhance degassing in powder coatings and other film-forming curable coatings are disclosed. The non-yellowing compositions contain degassing agents including a plurality of unfused aromatic rings and at least one functional group selected from ketals, carbamates, carbonates and carboxylic acid esters. The degassing agents resist decomposition and discoloration, and are relatively stable at resin curing conditions and. The degassing agents may be synergistically combined with other materials, such as fatty acid amide-containing waxes, to produce new and surprisingly effective degassing compositions suitable for use in powder coatings. Curable compositions which utilize the new degassing compositions are also disclosed. | 08-12-2010 |
Patent application number | Description | Published |
20110093220 | INTEGRATED ACOUSTIC LEAK DETECTION SYSTEM USING INTRUSIVE AND NON-INTRUSIVE SENSORS - A system for detecting and locating leaks includes a pipeline, strain sensors positioned on the external surface of the pipeline, acoustic pressure sensors positioned at intervals along the pipeline, local processors connected to the strain sensors and acoustic pressure sensors, and a central processor connected to the local processors. The strain sensors measure a strain on the external surface of the pipeline indicative of changes in the pressure of the fluid within the pipeline. The acoustic pressure sensors sense acoustic signals within the pipline. Sensed acoustic pressure signals and sensed strain measurements are compared to each other and to stored profiles to detect and locate leaks. | 04-21-2011 |
20110114119 | SCRAPER TRACKING SYSTEM - A tracking system for use with a pipeline includes a scraper having signal generation capability for generating acoustic signals, a plurality of acoustic pressure sensors positioned at intervals along the path travelled by the scraper, and a plurality of local processors positioned at intervals along the path travelled by the scraper. Each of the local processors is in communication with a respective acoustic pressure sensor. A central processor is in communication with the local processors and determines the location of the scraper using time-stamped acoustic signals received by the pressure sensors and a speed of sound in a fluid within the pipeline. | 05-19-2011 |
20130276250 | Trackable pipeline scraper for active tracking and locating - A tracking system for use with a pipeline includes a scraper having signal generation capability for generating acoustic signals, a plurality of acoustic pressure sensors positioned at intervals along the path traveled by the scraper, and a plurality of local processors positioned at intervals along the path traveled by the scraper. Each of the local processors is m communication with a respective acoustic pressure sensor. A central processor is in communication with the local processors and determines the location of the scraper using time-stamped acoustic signals received by the pressure sensors and a speed of sound, in a fluid within the pipeline. | 10-24-2013 |
20130279296 | TRACKING SYSTEM FOR A PIPELINE - A tracking system for use with a pipeline includes a scraper having signal generation capability for generating acoustic signals, a plurality of acoustic pressure sensors positioned at intervals along the path traveled by the scraper, and a plurality of local processors positioned at intervals along the path traveled by the scraper. Each of the local processors is in communication with a respective acoustic pressure sensor. A central processor is in communication with the local processors and determines the location of the scraper using time-stamped acoustic signals received by the pressure sensors and a speed of sound in a fluid within the pipeline. | 10-24-2013 |
Patent application number | Description | Published |
20120014884 | MENTHOL-DERIVATIVE COMPOUNDS AND USE THEREOF AS ORAL AND SYSTEMIC ACTIVE AGENTS - The present invention discloses novel uses of specific menthol-derivative compounds of Formula 1, and compositions thereof, for methods of providing oral and systemic health care benefits, and methods of up-regulating or down-regulating periodontal disease metabolites: Formula 1 wherein, X is an oxygen atom or an NH radical; and R is an unsubstituted or substituted aryl or aliphatic radical. In some embodiments, the oral and systemic health care benefits include biofilm anti-attachment, anti-inflammation, anti-oxidant, anti-bone loss, and anti-microbial benefits. In some embodiments, the periodontal disease metabolites correspond to healthy and/or diseased oral status and allow differential diagnosis of oral health. | 01-19-2012 |
20120028261 | PROTEIN BIOMARKERS FOR SOFT TISSUE DISEASE DIAGNOSIS AND AS THERAPEUTIC TARGETS FOR ORAL CARE INTERVENTION - Methods for identifying compounds useful for treating diseases or conditions of the oral cavity are described herein. | 02-02-2012 |
20120034282 | DENTIFRICE COMPOSITION AND METHOD OF USE - An exfoliating dentifrice composition is described that contains a plurality of granules and an orally acceptable vehicle. The granules include at least one polymeric binding agent. The composition includes at least one abrasive agent having an average particle diameter of 0.01 mm to 4 mm. Also included are methods of exfoliating an oral cavity soft tissue by use of the composition. | 02-09-2012 |
20120308489 | ORAL CARE COMPOSITIONS - Disclosed herein are methods of enhancing the solubility and delivery of one or more active ingredients found in magnolia extract, or a synthetic analogue thereof, in an oral composition. | 12-06-2012 |
20130129643 | ORAL CARE COMPOSITIONS - An oral care composition for treating or preventing calculus comprising an anticalculus agent and an antibacterial agent comprising a biphenol compound obtainable from | 05-23-2013 |
20130224271 | Oral Compositions Containing Microaggregates - The invention relates to a composite and oral care compositions for use in the mouth to retard the accumulation of dental plaque and/or calculus. The composite is a microaggregate comprising polymer coated, surfactant stabilized particles of a substantially insoluble metal, metal salt or metal oxide, for example zinc oxide. Also methods for retarding the accumulation of dental plaque and/or calculus are provided. | 08-29-2013 |
20140234232 | Oral and Skin Care Compositions Based on a 3,3-Dialkyl-1,1-Biphenyl-2,2-Diol or a 3,3-Dialkenyl-1,1-Biphenyl-2,2-Diol - Described herein are compositions comprising antibacterially effective amounts of a compound of Formula (I): or a salt thereof in which R | 08-21-2014 |
20140314688 | ORAL CARE COMPOSITIONS - Oral care compositions comprising isobutyl magnolol and n-butyl magnolol. A method of enhancing the solubility of isobutyl magnolol in an oral care composition comprises admixing n-butyl magnolol with an orally acceptable carrier comprising isobutyl magnolol. The composition may be used to treat diseases or conditions of the oral cavity such as caries, gingivitis, periodontitis, tooth yellowing and halitosis. | 10-23-2014 |
20140356299 | ORAL CARE COMPOSITIONS - The invention provides oral care compositions comprising isobutyl magnolol and propylene glycol monolaurate, together with methods of making and using the same. Also described is a method of enhancing the solubility of isobutyl magnolol in an oral care composition comprising effective amount of propylene glycol monolaurate. The composition is for use in the treatment of caries, gingivitis, periodontitis, tooth yellowing and halitosis. | 12-04-2014 |
Patent application number | Description | Published |
20090176804 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS - The present invention is directed to 2-phenyl-indole compounds, their preparation, pharmaceutical compositions containing these compounds, and their pharmaceutical use in treating a patient suffering from a PGD2-mediated disorder including, but not limited to, allergic disease (such as allergic rhinitis, allergic conjunctivitis, atopic dermatitis, bronchial asthma and food allergy), systemic mastocytosis, disorders accompanied by systemic mast cell activation, anaphylaxis shock, bronchoconstriction, bronchitis, eczema, urticaria diseases accompanied by itch (such as atopic dermatitis and urticaria), diseases (such as cataract, retinal detachment, inflammation, infection and sleeping disorders) which are generated secondarily as a result of behavior accompanied by itch (such as scratching and beating), inflammation, chronic obstructive pulmonary diseases, ischemic reperfusion injury, cerebrovascular accident, chronic rheumatoid arthritis, pleurisy, ulcerative colitis and the like. | 07-09-2009 |