Patent application number | Description | Published |
20080299210 | STABLE NANOSIZED AMORPHOUS DRUG - Disclosed is a population of nanoparticles, together with methods of making a population of nanoparticles, wherein one or more of the nanoparticles includes: an amorphous drug core having an effective diameter less than or equal to about 2.0 microns, wherein the amorphous drug core is substantially free of dopant, and wherein the amorphous drug core includes a drug with properties that satisfy the following relationships: a glass transition temperature greater than or equal to about 50 Deg. C., a glass forming ability less than or equal to about 0.85; and water solubility at 25 Deg. C. less than or equal to about 1 mg/ml; and at least one stabilizer adsorbed on a surface of the amorphous drug core; and wherein the population of nanoparticles exhibits greater than about six months amorphous stability. | 12-04-2008 |
20110022001 | PEN NEEDLE ASSEMBLY - A pen needle assembly is provided herein having a hub with a distal end and a proximal end; a needle fixed to the hub and having a distal end, for insertion into a patient, and a proximal end; an inner shield disposed proximally of the hub; a spring disposed between the inner shield and the hub and configured to bias the hub distally; an outer shield with a distal end, a proximal end, and a tubular body at least partially encircling a portion of the needle with at least portions located radially outward further from the needle than the inner shield such that the outer shield at least partially encases the hub, the needle, the inner shield, and the spring; and a releasable retaining assembly configured to releasably retain the hub in a first locked state against the biasing of the spring. The distal end of the needle is covered by the outer shield with the hub being in a first locked state. Upon release of the releasable retaining assembly, the hub moves under force of the spring to an unlocked second state. In the unlocked second state, the distal end of the needle extends distally from the distal end of the outer shield. Advantageously, with the arrangement of the subject invention, an injection may be conducted properly by a person apprehensive of seeing a needle during a medical injection and may also help a person insert the needle at the proper angle. | 01-27-2011 |
20110092917 | DRUG DELIVERY DEVICE HAVING CARTRIDGE WITH ENLARGED DISTAL END - A drug delivery device is provided herein which includes a tubular body having a proximal end and a distal end, the tubular body defining an opening at or in proximity to the distal end, the opening defining an inner diameter. A drug cartridge is also provided having a proximal end, a distal end and a barrel portion disposed therebetween. The distal end of the drug cartridge is larger in diameter than the inner diameter of the opening. The drug cartridge is inserted into the tubular body to a use position by first inserting the proximal end of the drug cartridge into the opening. The distal end of the drug cartridge limits insertion of the drug cartridge into the tubular body due to the interengagement of the distal end of the drug cartridge and the tubular body. With the drug cartridge being in the use position, the distal end of the drug cartridge is located at least partially externally of the tubular body. The medical pen injector of the subject invention further includes an adaptor engageable with the body. The adaptor encompasses the distal end of the drug cartridge with the drug cartridge being in the use position. The adaptor includes features for mounting a needle assembly thereto. Advantageously, with the subject invention, a drug cartridge having a large distal end may be accommodated with a drug delivery device, e.g., a pen injector type device. | 04-21-2011 |
20110106016 | PEN NEEDLE ASSEMBLY - A pen needle assembly is provided herein for use with a medical injector containing an injector body and a reservoir sealed by a septum encased in the injector body. The pen needle assembly includes a hub and a needle fixed to the hub. The hub is formed to be telescopingly mounted onto the distal end of the injector body using a track that accommodates a guide key. When mounting the pen needle assembly onto the injector body, a first portion of the track is configured to receive the guide key and to guide the guide key in a straight line across sufficient distance to permit the proximal end of the needle to fully pierce through the septum, without rotation of the needle. A second portion of the track is configured to permit the pen needle assembly to be turned with the proximal end of the needle being located proximally of the septum. | 05-05-2011 |
20110270222 | Injection Pen For Intradermal Medication Injection - A pen body assembly ( | 11-03-2011 |
20110288526 | Pen Needle Assembly For Intradermal Injection - A pen needle assembly ( | 11-24-2011 |
20120109052 | PEN NEEDLE ASSEMBLY FOR DELIVERING DRUG SOLUTIONS - In one aspect, a pen needle assembly is provided herein which includes a hub, and a needle fixed to the hub, the needle having proximal and distal ends with a lumen extending therebetween. The needle extends distally from the hub to define an exposed length between the distal end of the needle and the hub in the range of about 5.0 to 9.0 mm. The hub defines a post formed about the needle, the post having a distally-facing first skin engaging surface. The exposed length of the needle extends distally from the first skin engaging surface. The hub also defines a distally-facing second skin engaging surface which at least partially circumscribes the first skin engaging surface. The second skin engaging surface being located proximally of the first skin engaging surface. Advantageously, with the subject invention, a pen needle assembly is provided having two skin engaging surfaces which provide stability in achieving subcutaneous injections. | 05-03-2012 |
20120209171 | CARTRIDGE FOR POWDER AND LIQUID DRUG - A cartridge or injector for holding and mixing a medical product is provided herein including a tubular body having a cylindrical wall having first and second opposing ends. The wall includes inner and outer surfaces with the inner surface having a generally constant cross-section along at least a drug mixing area. A first stopper is slidably disposed within the wall between the first and second ends, the first stopper defining a liquid-tight seal with the inner surface. A second stopper is slidably disposed within the wall between the first stopper and the first end, the second stopper defining a liquid-tight seal with the inner surface. A flexible insert is disposed at or in proximity to the second end, the insert forming a liquid-tight seal with the wall, the insert being pierceable by a medical needle or other piercing instrument. A rigid retainer is fixed to the wall having an opening therein for providing access to the insert for piercing by a medical needle. The insert extends into the retainer and forms a liquid-tight seal across the opening. Advantageously, with the subject invention, a reconstitution assembly may be provided which has a sufficiently large distal opening during assembly which allows a dry component to be introduced into the device in a dry state. | 08-16-2012 |
20120259281 | SAFETY NEEDLE ASSEMBLY WITH DISPLACEABLE LOCKING TONGUE - A safety needle assembly is provided herein which includes a displaceable locking tongue which has a first position in which the locking tongue covers an aperture formed in a shield so as to prevent the passage therethrough of a needle. A biasing element is also provided for urging the locking tongue to the first position. The locking tongue is releasably retained in a retained position prior to use of the safety needle assembly, the aperture being sufficiently uncovered with the locking tongue being in the retained position so as to permit passage of the needle through the aperture. The locking tongue is releasably retained in the retained position against biasing force of the biasing element. With the shield being displaced proximally from a first position to a second position, the locking tongue is released from the retained position and permitted to be displaced to the first position under force of the biasing element. Advantageously, with the subject invention, a safety needle assembly is provided which covers a used needle after use and, optionally, provides a use indicator. | 10-11-2012 |
Patent application number | Description | Published |
20100161289 | FRAMEWORK FOR INTEROPERABILITY OF SOLVERS - A framework may be provided for facilitating adoption of mathematical and logical solvers. A model, representing a problem, may be defined. The model may be defined: via a series of statements in a type safe common-language-specification compliant modeling language; via an intermediate format; or via a series of calls to a standardized application program interface. The framework may translate the defined model to an intermediate format, which many solvers may understand. The framework may provide a number of solver-related services including, but not limited to, services for creating a model, analyzing a model, selecting a well-suited solver based on analysis of a model, decomposing a model into multiple sub-models and providing the multiple sub-models to multiple solvers as multiple parallel threads, data binding, simulation, and post optimality analysis. | 06-24-2010 |
20100169257 | TRANSPARENT PARALLELISM AMONG LINEAR SOLVERS - A model, which defines a mathematical problem, and multiple directives may be received. Each of the multiple directives may be mapped to a respective linear solver instance. The linear solver instances may be launched to execute in parallel. Each of the linear solver instances may use either a primal or a dual algorithm and may further use double arithmetic, exact arithmetic, or hybrid arithmetic, as specified by corresponding ones of the multiple directives. A linear solver instance that uses hybrid arithmetic may start by using double arithmetic and may use exact arithmetic after experiencing a numerical difficulty. After the numerical difficulty is resolved, the linear solver instance that uses hybrid arithmetic may restart and continue to solve the mathematical problem using double arithmetic. After one of the linear solver instances finds an optimal solution, others of the linear solver instances may be stopped and a report may be provided. | 07-01-2010 |
20100306009 | SPECIAL-ORDERED-SET-BASED COST MINIMIZATION - An embodiment of the invention is directed toward determining a solution to an objective function that is to be maximized or minimized. An initial feasible basis is determined. An entering variable is determined to enter the initial feasible basis. It is determined if there is an exiting variable. While there is an exiting variable, the exiting variable is removed from the feasible basis, the entering variable is added to the feasible basis, and a new entering variable is determined. | 12-02-2010 |
Patent application number | Description | Published |
20100262710 | RENDERING IN A MULTI-USER VIDEO EDITING SYSTEM - Methods and systems for remotely editing a video file involve: receiving, at a server, a video editing command from a remote client; modifying, at the server, a virtual representation of a media file in accordance with the received command, the virtual representation including a reference to a source media file stored on a storage device, the storage device being connected to the server over a high-speed link; and generating and transmitting, from the server to the remote client, a proxy representation of the source media file modified by the editing commands, wherein the various regions of the proxy representation are rendered either in the background or in real-time according to their complexity. Rendered frames, whether generated in the background or in real time, are stored for reuse. Individual frames of the edited video file may be transmitted upon request from a client. Simultaneous editing of independent projects by multiple users connected to the server via multiple thin clients is supported. | 10-14-2010 |
20140033042 | RENDERING IN A MULTI-USER VIDEO EDITING SYSTEM - Methods and systems for remotely editing a video file involve: receiving, at a server, a video editing command from a remote client; modifying, at the server, a virtual representation of a media file in accordance with the received command, the virtual representation including a reference to a source media file stored on a storage device, the storage device being connected to the server over a high-speed link; and generating and transmitting, from the server to the remote client, a proxy representation of the source media file modified by the editing commands, wherein the various regions of the proxy representation are rendered either in the background or in real-time according to their complexity. Rendered frames, whether generated in the background or in real time, are stored for reuse. Individual frames of the edited video file may be transmitted upon request from a client. Simultaneous editing of independent projects by multiple users connected to the server via multiple thin clients is supported. | 01-30-2014 |
20140304603 | FULL FIDELITY REMOTE VIDEO EDITING - Video editing methods and systems enable an editor to edit a video project for which source media assets are located at a media storage server located remotely from the editor with substantially the same fidelity and editing feature set that would be available if the source media assets and editor were co-located. A video editing client used by the editor maintains a persistent cache of proxy media with the layers of the video project stored independently, facilitating editing with combinations locally originated assets and remote assets. The client requests frames not already cached from the remote server via a low bandwidth network. Unless a frame is purged from the cache, no frame is requested from the server more than once. A multi-level priority prefetching scheme, including sequence-based prefetching, populates the cache with frames likely to be requested during editing. | 10-09-2014 |
Patent application number | Description | Published |
20100130750 | Benzocarbazole-intercalated layered double hydroxides composite luminescent material and its preparation method - The present invention discloses a benzocarbazole-intercalated layered double hydroxides (LDHs) composite luminescent material and its preparation method. The detailed procedure comprises preparing divalent and trivalent metal cation solution A and glycol solution B of sodium 2-hydroxy benzo[a]carbazole-3-carboxylate, mixing the solutions A and B to obtain solution C, slowly adding the prepared NaOH solution dropwise into the solution C, regulating pH of the resultant after dropwise addition to obtain slurry D, allowing the slurry D to react under water bath or microwave temperature-controlled heating condition, centrifuging and washing the obtained product, and drying in vacuum to obtain 2-hydroxy benzo[a]carbazole-3-carboxylate anion intercalated LDHs composite material. The method implements the immobilization of sodium 2-hydroxy benzo[a]carbazole-3-carboxylate, effectively improves thermal stability of the luminescent dye molecules, and reduces fluorescence quenching caused by aggregation of the dye molecules. | 05-27-2010 |
20100219378 | Preparation method of composite luminescent thin film of sulfonated poly (p-phenylene) and layered double hydroxides - The present invention provide a preparation method of composite blue luminescent thin film of sulfonated poly(p-phenylene) (i.e. poly[2,5-bis(3-sulfonatopropoxy)-1,4-phenylene-alt-1,4-phenylene]) and LDHs (Layered Double Hydroxides). The preparation method comprises following steps: preparing delaminated LDHs colloidal solution using formamide solvent, preparing sulfonated poly(p-phenylene) aqueous solution, performing alternate assembling on hydrophilically treated substrate in the two solutions to give the composite thin film of sulfonated poly(p-phenylene)/LDHs multilayer. The present invention has the advantages of simple preparation process, and film thickness controllable at nanoscale precision; the invention also achieves the immobilization of luminescent polymer via restricted space among LDHs layers and host-guest interaction, effectively improves thermal stability, and reduces fluorescence quenching caused by aggregation. | 09-02-2010 |
20120240821 | UV-SHIELDING MATERIAL BASED ON MG-AL LAYERED DOUBLE HYDROXIDE AND ITS APPLICATION IN ANTI-AGEING ASPHALT - The present invention relates to a preparation method for a UV-shielding material based on Mg—Al Layered Double Hydroxide. The material with multi-layered overlay structure is made from Mg—Al double hydroxide layers and interlayer carbonate, its molecular composition is: Mg | 09-27-2012 |
20120282706 | PREPARATION OF AN OPTICAL PH SENSOR BASED ON FLUORESCEIN AND 1-HEPTANESULFONIC ACID SODIUM CO-INTERCALATED LAYERED DOUBLE HYDROXIDE - This invention relates to the field of preparation technology of optical pH sensor by co-intercalated fluorescein and 1-heptanesulfonic acid sodium into layered double hydroxide. The sensor is composed by conductive materials and the surface LDH films by co-interacted FLU and HES. The synthesis method is: first: synthesis of LDH colloid suspension, subsequently, the FLU and HES co-intercalated LDH colloid solution was prepared following the ion-exchange method, then the thin film of FLU-HES/LDH was spreaded on the surface of the conductive material by electrophoretic deposition, and the oriental pH sensor was synthesized. The advantages of the present invention is: first, the LDH matrix provides chromophore molecules with a confined and stable environment; the novel electrophoretic deposition strategy in this work provides a method for precise control of thickness (ranging from nanometers to micrometers), and the oriental pH sensor show good pH responsive. | 11-08-2012 |
Patent application number | Description | Published |
20120106317 | Multi-User Multiplexing Method And Transmission Device - The present invention provides a method and apparatus for multi-user multiplexing. The method includes: a transmission apparatus performing layer mapping on data steams to be transmitted of an open-loop user and a close-loop user respectively; the transmission apparatus performing pre-coding processing on a layer data matrix of the open-loop user and the close-loop user obtained by the layer mapping; and the transmission apparatus mapping the layer data matrix after the pre-coding processing to a plurality of transmission antennas to be sent. The method of the present invention can improve frequency spectrum utilization ratio in the case of the a cell being full load or other possible scenarios, and its performance is better than the multiplexing of two close-loop users who are completely not suitable for pairing. Therefore, the method of the present invention is an optimal scheme adopted in some specified scenarios. | 05-03-2012 |
20120252515 | Coordinated scheduling method and system in coordinated multi-point transmission - The present disclosure provides a coordinated scheduling method and system in coordinated multi-point transmission. The method includes: a central control cell of a region determines priorities of users to be scheduled in all coordinated cells according to user information from other coordinated cells in the region; the central control cell schedules users in each coordinated cell according to the determined priorities and informs a corresponding coordinated cell of the information on a user that is finally determined to be scheduled; and after receiving the scheduling information from the central control cell, the corresponding coordinated cell schedules a user in corresponding time and frequency resources. The present disclosure ensures performance of a user with the highest priority, further, considering the performance of the whole system, scheduling is performed in a scheduling stage according to a principle that the subsequent users to be scheduled should cause as little interference on the scheduled users as possible, therefore, the interference between scheduled users is effectively reduced, and the capacity of the system is greatly increased. | 10-04-2012 |
20120322499 | Method and system for handover based on radio resource allocation database - The disclosure discloses a method for handover based on a radio resource allocation database. The method includes that the radio resource allocation database is constructed and dynamically maintained; after receiving a handover request from a User Equipment (UE), a Base Station (BS) determines in the database a Radio Access Technology (RAT) and the corresponding carrier frequency resources suitable for a current communication condition of the UE for the UE according to a handover reason in the handover request, and notifies the UE of information regarding the determined RAT and information regarding the corresponding carrier frequency resource; and the UE performs QoS verification on the RAT and the corresponding carrier frequency resources notified by the BS, and switches to the corresponding carrier frequency with the RAT notified by the BS when the QoS on the RAT and the corresponding carrier frequency resources is superior to that of current communication. Meanwhile, the disclosure further discloses a system for handover based on a radio resource allocation database. The disclosure improves a resource usage rate and the QoS of a current communication system. The disclosure enables the UE to complete the handover quickly, such that user experience is improved. | 12-20-2012 |
20140038659 | Method and Device for Controlling Power of Cognitive Radio System - The disclosure provides a method and a device for controlling power of a cognitive radio system. The method comprises: measuring a system parameter of a cognitive radio system and a system parameter of a TV system located in an adjacent channel of the cognitive radio system; determining a maximum transmission power of the cognitive radio system according to the system parameter of the cognitive radio system and the system parameter of the TV system; controlling an actual transmission power of the cognitive radio system to be less than the maximum transmission power. In the disclosure, interference to the TV system can be reduced maximally, so that the sensitivity of a receiver inside the TV system is guaranteed. | 02-06-2014 |
20140344276 | Method and System for Generating Evaluation Information, and Computer Storage Medium - A method for generating evaluation information, including the following steps: obtaining first information from user behavior information; determining whether the first information matches key matching information, and if yes, then obtaining a category to which the key matching information corresponding to the first information belongs; and generating evaluation information according to the category. The method and system for providing evaluation information, and a corresponding computer storage medium, obtain first information from the user behavior information, and obtain a corresponding category according to the first information which matches the preset key matching information, thus generating evaluation information corresponding to the category. The generated evaluation information varies as the first information varies, and dynamic adjustment of evaluation information is achieved. | 11-20-2014 |
Patent application number | Description | Published |
20130084896 | Pushing Secure Notifications to Mobile Computing Devices - A method for pushing secure notifications includes a push service platform receiving a push notification message request from an entity registered with the push service platform, processing the push notification message request to generate a secure push notification message, and sending the secure push notification message to a target mobile computing device through a native third-party push service associated with the target mobile computing device. The secure push notification message includes a message ID (identifier) that corresponds to message content associated with the push notification message request. The method further includes the push service platform receiving a pull message request from the target mobile computing device, the pull message request requesting the message content associated with the push notification message corresponding to the message ID, and sending the requested message content associated with the push notification message to the mobile computing device. | 04-04-2013 |
20140038554 | PUSHING SECURE NOTIFICATIONS TO MOBILE COMPUTING DEVICES - Techniques are provided for pushing secure notifications to a mobile computing device. For example, a method for pushing secure notifications includes a push service platform receiving a push notification message request from an entity registered with the push service platform, processing the push notification message request to generate a secure push notification message, and sending the secure push notification message to a target mobile computing device through a native third-party push service associated with the target mobile computing device. The secure push notification message includes a message ID (identifier) that corresponds to message content associated with the push notification message request. The method further includes the push service platform receiving a pull message request from the target mobile computing device, the pull message request requesting the message content associated with the push notification message corresponding to the message ID, and sending the requested message content associated with the push notification message to the mobile computing device. | 02-06-2014 |
20160037349 | PUSHING SECURE NOTIFICATIONS TO MOBILE COMPUTING DEVICES - Techniques are provided for pushing secure notifications to a mobile computing device. For example, a method for pushing secure notifications includes a push service platform receiving a push notification message request from an entity registered with the push service platform, processing the push notification message request to generate a secure push notification message, and sending the secure push notification message to a target mobile computing device through a native third-party push service associated with the target mobile computing device. The secure push notification message includes a message ID (identifier) that corresponds to message content associated with the push notification message request. The method further includes the push service platform receiving a pull message request from the target mobile computing device, the pull message request requesting the message content associated with the push notification message corresponding to the message ID, and sending the requested message content associated with the push notification message to the mobile computing device. | 02-04-2016 |