Patent application number | Description | Published |
20090317490 | SUBSTITUTED CHROMAN DERIVATIVES, MEDICAMENTS AND USE IN THERAPY - Novel substituted chroman derivatives and intermediate compounds, compositions containing same, methods for their preparation and uses thereof as therapeutic agents particularly as anti-cancer and chemotherapeutic selective agents are described. | 12-24-2009 |
20120004296 | CHROMAN DERIVATIVES, MEDICAMENTS AND USE IN THERAPY - Novel chroman derivatives and intermediate compounds, compositions containing same, methods for their preparation and uses thereof as therapeutic agents particularly as anti-cancer and chemotherapeutic selective agents are described. | 01-05-2012 |
20120172424 | CHROMAN DERIVATIVES, MEDICAMENTS AND USE IN THERAPY - Novel chroman derivatives and intermediate compounds, compositions containing same, methods for their preparation and uses thereof as therapeutic agents particularly as anti-cancer and chemotherapeutic selective agents are described. | 07-05-2012 |
20140161908 | CHROMAN DERIVATIVES, MEDICAMENTS AND USE IN THERAPY - Novel chroman derivatives and intermediate compounds, compostions containing same, methods for their preparation and uses thereof as therapeutic agents particularly as anti-cancer and chemotheraputic selective agents are described. | 06-12-2014 |
20150238458 | CHROMAN DERIVATIVES, MEDICAMENTS AND USE IN THERAPY - Novel chroman derivatives and intermediate compounds, compositions containing same, methods for their preparation and uses thereof as therapeutic agents particularly as anti-cancer and chemotherapeutic selective agents are described. | 08-27-2015 |
Patent application number | Description | Published |
20090131513 | ANTI-INFLAMMATORY MODALITIES - Anti-inflammatory modalities are described with reference to select isoflavonoid compounds, compositions containing same and the use of said compounds and/or compositions in treatment, particularly for the treatment of inflammatory diseases and related conditions. | 05-21-2009 |
20100152284 | PREVENTION AND REVERSAL OF CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY - Provided herein are methods for treating or preventing neuropathy, neuropathy-related conditions, wherein the neuropathy or neuropathy-related conditions are induced by, or otherwise associated with, treatment of the subject with at least one chemotherapeutic agent, the methods comprising administering an effective amount of an isoflavonoid compound of formula (I). Also provided are methods for the treatment of nerve damage. Also provided are uses of isoflavonoid compounds of formula (I) in the treatment of neuropathy, neuropathy-related conditions and nerve damage. | 06-17-2010 |
20100173983 | METHOD FOR INDUCING AUTOPHAGY - The present invention relates to methods for inducing or promoting autophagy in a cell, the method comprising exposing to the cell an effective amount of a compound of formula I as described herein. The invention also relates to methods for treating or preventing diseases and disorders by administering to subjects in need thereof an effective amount of a compound of formula I, wherein the compound induces or promotes autophagy in at least one cell of the subject. | 07-08-2010 |
20110166142 | 2-SUBSTITUTED ISOFLAVONOID COMPOUNDS, MEDICAMENTS AND USES - 2-Substituted isoflavonoid compounds and pharmaceutical compositions containing same are useful as anti-inflammatory agents and antioxidants and for the treatment of related diseases and conditions. | 07-07-2011 |
Patent application number | Description | Published |
20100130598 | METHODS FOR INDUCING PROGRAMMED CELL DEATH - The present invention relates to methods for inducing or promoting caspase-independent apoptosis in a cell, the method comprising exposing to the cell an effective amount of a compound of formula I as described herein. The invention also relates to methods for treating or preventing diseases and disorders by administering to subjects in need thereof an effective amount of a compound of formula I, wherein the compound induces or promotes caspase-independent apoptosis in at least one cell of the subject. | 05-27-2010 |
20120039917 | IMMUNOMODULATING ACTIVITIES - Composition of isoflavonoids and chromanols and use of them as immunomodulators and as inhibitors of T-cell or T-lymphocyte proliferation. Treatment of disorders involving abnormal proliferation or activity of T cells. Formula (I) where A is hydrogen or optionally substituted phenyl and R1 represents hydroxy, alkoxy, halo or an ester and R2-R8 represent hydogen, hydroxy, alkyl etc. | 02-16-2012 |
20120059176 | ANTI-INFLAMMATORY MODALITIES - Anti-inflammatory modalities are described with reference to select isoflavonoid compounds, compositions containing same and the use of said compounds and/or compositions in treatment, particularly for the treatment of inflammatory diseases and related conditions. | 03-08-2012 |
20140170243 | SUBSTITUTED CHROMAN DERIVATIVES, MEDICAMENTS AND USE IN THERAPY - Novel substituted chroman derivatives and intermediate compounds, compositions containing same, methods for their preparation and uses thereof as therapeutic agents particularly as anti-cancer and chemotherapeutic selective agents are described. | 06-19-2014 |
20150352074 | SUBSTITUTED CHROMAN DERIVATIVES, MEDICAMENTS AND USE IN THERAPY - Novel substituted chroman derivatives and intermediate compounds, compositions containing same, methods for their preparation and uses thereof as therapeutic agents particularly as anti-cancer and chemotherapeutic selective agents are described. | 12-10-2015 |
Patent application number | Description | Published |
20140174300 | BEVERAGE FILTER ASSEMBLY - Beverage filter kit usable with a brewing the kit comprising a reusable insert configured to be received within a brewing cavity of the brewing device; and a disposable filter assembly configured to be received within the insert and comprising a substance suitable for preparing a brewed beverage. Filter assembly usable with a brewing device, the filter assembly comprising a paper-based lid portion; a paper-based filter portion; and a substance contained between the lid portion and the filter portion suitable for preparing a brewed beverage; the filter assembly is configured to be received within a brewing chamber of the brewing device. Reusable insert usable with a filter assembly and brewing device for preparation of a brewed beverage, the insert comprising a top, a bottom, and a sidewall forming a cavity to receive a filter assembly, the filter assembly comprising a substance for preparing a brewed beverage; a plurality of elongated protrusions extending along at least a portion of the sidewall between the top and the bottom; and an aperture provided on the bottom to provide an exit for a brewed beverage flowing through the filter assembly within the insert. | 06-26-2014 |
20140178538 | BEVERAGE FILTER CARTRIDGE - Beverage filter cartridge comprising a cup having at least one sidewall; a cover sealed to the cup to form an interior; and a filter pod provided the interior and having a substance provided therein for brewing a beverage; wherein at least a portion of the sidewall comprises a helical channel extending the cup. | 06-26-2014 |
20140287105 | BEVERAGE FILTER SYSTEMS - A beverage filter cartridge comprising a cup portion; a lid portion coupled to the cup portion to define an interior; and a filter member provided within the interior; wherein the cup portion, the lid portion, and/or the filter member define three separate compartments with the interior. | 09-25-2014 |
Patent application number | Description | Published |
20130287575 | Geared Architecture for High Speed and Small Volume Fan Drive Turbine - A gas turbine engine includes a flex mount for a fan drive gear system. A very high speed fan drive turbine drives the fan drive gear system. | 10-31-2013 |
20130320185 | TURBOMACHINE GEARED ARCHITECTURE SUPPORT ASSEMBLY - An example turbomachine geared architecture support assembly includes a compliant member configured to hold a geared architecture within a turbomachine. The compliant member has a compliant section that permits rotation of the geared architecture relative to a fixed portion of the turbomachine. A stop limits rotation of the geared architecture relative to the fixed portion of the turbomachine. | 12-05-2013 |
20130331223 | FLEXIBLE SUPPORT STRUCTURE FOR A GEARED ARCHITECTURE GAS TURBINE ENGINE - A geared architecture for a gas turbine engine according to an exemplary aspect of the present disclosure includes, among other things, a fan shaft, a frame which supports the fan shaft, the frame defines a frame stiffness and a plurality of gears which drives the fan shaft. A flexible support defines a flexible support stiffness that is less than the frame stiffness. The plurality of gears are supported by at least one of a carrier and the flexible support and an input coupling to the plurality of gears, the input coupling defines an input coupling stiffness with respect to the frame stiffness. | 12-12-2013 |
20130331224 | FLEXIBLE SUPPORT STRUCTURE FOR A GEARED ARCHITECTURE GAS TURBINE ENGINE - A geared architecture for a gas turbine engine according to an exemplary aspect of the present disclosure includes, among other things, a fan shaft and a frame which supports the fan shaft, the frame defines a frame stiffness. A plurality of gears drives the fan shaft. A flexible support at least partially supports the plurality of gears, the flexible support defines a flexible support stiffness that is less than the frame stiffness. An input coupling to the plurality of gears, the input coupling defines an input coupling stiffness with respect to the frame stiffness. | 12-12-2013 |
20130336791 | Geared Architecture for High Speed and Small Volume Fan Drive Turbine - A gas turbine engine includes a flex mount for a fan drive gear system. A very high speed fan drive turbine drives the fan drive gear system. | 12-19-2013 |
20140020404 | FUNDAMENTAL GEAR SYSTEM ARCHITECTURE - A fan drive gear system for a gas turbine engine includes a gear system that provides a speed reduction between a fan drive turbine and a fan and a mount flexibly supporting portions of the gear system. A lubrication system supporting the fan drive gear system provides lubricant to the gear system and removes thermal energy produced by the gear system. The lubrication system includes a capacity for removing energy equal to less than about 2% of energy input into the gear system. | 01-23-2014 |
20140133958 | Flexible Support Structure For A Geared Architecture Gas Turbine Engine - A gas turbine engine includes a fan shaft and a support which supports the fan shaft. The support defines at least one of a support transverse and a support lateral stiffness. A gear system drives the fan shaft. A flexible support at least partially supports the gear system, and defines at least one of a flexible support transverse and a flexible support lateral stiffness with respect to at least one of the support transverse and the support lateral stiffness. An input to the gear system defines at least one of an input transverse and an input lateral stiffness with respect to at least one of the support transverse and the support lateral stiffness. A method of designing a gas turbine engine is also disclosed. | 05-15-2014 |
20140140819 | Flexible Support Structure For A Geared Architecture Gas Turbine Engine - A gas turbine engine includes a fan shaft and a support which supports the fan shaft. The support defines a support lateral stiffness. A gear system drives the fan shaft. A flexible support at least partially supports the gear system, and defines a flexible support lateral stiffness with respect to the support lateral stiffness. An input to the gear system defines an input lateral stiffness with respect to the support lateral stiffness. A method of designing a gas turbine engine is also disclosed. | 05-22-2014 |
20140234079 | Geared Architecture for High Speed and Small Volume Fan Drive Turbine - A gas turbine engine includes a flex mount for a fan drive gear system. A very high speed fan drive turbine drives the fan drive gear system. | 08-21-2014 |
20150345398 | FLEXIBLE SUPPORT STRUCTURE FOR A GEARED ARCHITECTURE GAS TURBINE ENGINE - A gas turbine engine includes a fan shaft and a support which supports the fan shaft. The support defines at least one of a support transverse and a support lateral stiffness. A gear system drives the fan shaft. A flexible support at least partially supports the gear system, and defines at least one of a flexible support transverse and a flexible support lateral stiffness with respect to at least one of the support transverse and the support lateral stiffness. An input to the gear system defines at least one of an input transverse and an input lateral stiffness with respect to at least one of the support transverse and the support lateral stiffness. A method of designing a gas turbine engine is also disclosed. | 12-03-2015 |
20160003084 | THERMALLY CONFORMABLE LINER FOR REDUCING SYSTEM LEVEL FAN BLADE OUT LOADS - A fan case for a gas turbine engine includes a fan case surrounding a fan with fan blades. A liner is disposed between the fan case and the fan and is spaced a radial distance from the fan case. A torque stop is arranged between the fan case and the liner. A method for reducing fan case liner loads is also disclosed. | 01-07-2016 |
20160053635 | FLEXIBLE SUPPORT STRUCTURE FOR A GEARED ARCHITECTURE GAS TURBINE ENGINE - A gas turbine engine according to an example of the present disclosure includes, among other things, a fan shaft configured to drive a fan, a support configured to support at least a portion of the fan shaft, the support defining a support transverse stiffness and a support lateral stiffness, a gear system coupled to the fan shaft, and a flexible support configured to at least partially support the gear system. The flexible support defines a flexible support transverse stiffness with respect to the support transverse stiffness and a flexible support lateral stiffness with respect to the support lateral stiffness. The input defines an input transverse stiffness with respect to the support transverse stiffness and an input lateral stiffness with respect to the support lateral stiffness. | 02-25-2016 |
Patent application number | Description | Published |
20090020465 | STANDPIPE WITH FLOW RESTRICTION VALVE, AND FILTER CARTRIDGE - A “no filter, no run” filtration system that is designed to verify that a filter cartridge is present to safe-guard against damage to fuel injectors, associated fuel components, etc. and engine malfunctions. Fuel flow to the engine is prevented altogether or permitted in an amount insufficient to allow engine operation if a filter cartridge is not installed, and an appropriately designed filter cartridge is required to be used in order to permit sufficient fuel flow for engine operation. In one embodiment, a flow restriction valve is provided that includes a ball. | 01-22-2009 |
20090057219 | Replaceable filter elements including unique interfaces and filtration systems including same - One embodiment is a replaceable filter element including a filter media having a first end, a second end and an interior cavity, and an endplate coupled to the first end of the filter media, the endplate including a projection extending from the endplate, the projection including a first portion, a flange and a second portion, the first portion extending from the endplate to the flange, the second portion extending from the flange. Further embodiments, forms, objects, features, advantages, aspects, and benefits shall become apparent from the following description and drawings. | 03-05-2009 |
20110073538 | STANDPIPE WITH FLOW RESTRICTION VALVE, AND FILTER CARTRIDGE - A “no filter, no run” filtration system that is designed to verify that a filter cartridge is present to safe-guard against damage to fuel injectors, associated fuel components, etc. and engine malfunctions. Fuel flow to the engine is prevented altogether or permitted in an amount insufficient to allow engine operation if a filter cartridge is not installed, and an appropriately designed filter cartridge is required to be used in order to permit sufficient fuel flow for engine operation. In one embodiment, a flow restriction valve is provided that includes a ball. | 03-31-2011 |
Patent application number | Description | Published |
20090091198 | FLUX-SWITCHING MACHINE - A flux-switching machine stator comprising two or more C-cores, each C-core having two legs and a back portion joining the legs, and a permanent magnet arranged between legs of adjacent C-cores. Each leg has a main portion and a tip portion further from the back portion characterized in that the tip portion of each leg is angled relative to the main portion of the respective leg. | 04-09-2009 |
20130119800 | DYNAMO-ELECTRIC MACHINE - A dynamo-electric machine, for example a marine propulsion unit, includes a stator and a rotor in the form of an impeller. The impeller is rim-driven and includes an annular core of ferromagnetic material, on which are provided layers in the form of an environmental enclosure and electrically conductive sleeves. Appropriate selection of the materials and thicknesses of the layers enables the starting and normal running performance of the machine to be optimised. | 05-16-2013 |
20130194703 | CURRENT LIMITER - This invention relates to a current limiter comprising a first circuit portion arranged in parallel with a second circuit portion, the first circuit portion comprising a superconductor element arranged in series with a switching arrangement, the second circuit portion comprising a load element, the superconductor element being disposed within a cooling chamber, and the cooling chamber and the switch being disposed within a vacuum chamber, wherein the switching arrangement comprises: a mechanical actuator which is operable between a closed condition in which current is conducted through the first circuit portion and an open condition in which current is diverted from the first circuit portion through the second circuit portion and a controller for monitoring and operating the switch. | 08-01-2013 |
20140342165 | ELECTRICAL APPARATUS ENCAPSULANT - An encapsulant composition has a silica containing inorganic-organic nano-hybrid matrix, particles of refractory ceramics suspended in the inorganic-organic nano-hybrid matrix, and, optionally, glass or ceramic fibres. The encapsulant may also contain ceramic coated metallic particles, and in some embodiments, a solvent or binder. The formulations can include a solvent, which may be removed during a curing process, or may be solvent-less | 11-20-2014 |
20150315980 | GAS TURBINE ENGINE FUEL SYSTEM - The present application discloses a fuel system for a gas turbine engine. The engine includes a main alternating current electrical generator driven by an engine shaft such that the electrical output frequency of the electrical generator varies in dependence on shaft rotational speed. The fuel system includes a variable flow fuel pump for providing a fuel flow to the engine, a frequency and/or voltage controller configured to provide electrical power having at least one of a predetermined output frequency and a predetermined voltage, and a variable speed electric motor configured to drive the fuel pump. The electric motor includes an induction motor having a stator and at least a first rotor, the stator having first and second sets of stator windings. Each set of stator windings is configured to impart a torque on the rotor in use. | 11-05-2015 |