Forst
Andrea Forst, Bayreuth DE
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20090203135 | Glycoconjugates of RNA Interference Agents - The present invention relates to agents, compositions and methods for inhibiting the expression of a target gene, comprising an RNAi agent bearing at least one galactosyl moiety. These are useful for delivering the gene expression inhibiting activity to cells, particularly hepatocytes, and more particularly in therapeutic applications. | 08-13-2009 |
20100197773 | COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF PTP1B GENES - This invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a PTP1B gene. The invention also relates to a pharmaceutical composition comprising the dsRNA or nucleic acid molecules or vectors encoding the same together with a pharmaceutically acceptable carrier; methods for treating diseases caused by the expression of a PTP1B gene using said pharmaceutical composition; and methods for inhibiting the expression of PTP1B in a cell. | 08-05-2010 |
20110020300 | COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF GLUCOCORTICOID RECEPTOR (GCR) GENES - This invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a GCR gene. The invention also relates to a pharmaceutical composition comprising the dsRNA or nucleic acid molecules or vectors encoding the same together with a pharmaceutically acceptable carrier; methods for treating diseases caused by the expression of a GCR gene using said pharmaceutical composition; and methods for inhibiting the expression of GCR in a cell. | 01-27-2011 |
20150065558 | Glycoconjugates of RNA Interference Agents - The present invention relates to agents, compositions and methods for inhibiting the expression of a target gene, comprising an RNAi agent bearing at least one galactosyl moiety. These are useful for delivering the gene expression inhibiting activity to cells, particularly hepatocytes, and more particularly in therapeutic applications. | 03-05-2015 |
Douglas Forst, North Vancouver CA
Heinz Forst, Aichwald DE
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20130032012 | Machine Tool - A lathe is provided that can produce complex shapes. The lathe includes a turret movement system with a B axis, which can be activated by a control. The turret axis may be designed as an H axis, which extends in a place at right angles to the B axis and can be activated by the control. | 02-07-2013 |
Howard Robert Forst, Columbus, IN US
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20150306957 | SYSTEMS AND METHODS FOR VEHICLE SPEED MANAGEMENT - Controlling a speed of a vehicle based on at least a portion of a route grade and a route distance divided into a plurality of route sections, each including at least one of a section grade and section length. Controlling the speed of the vehicle is further based on determining a cruise control speed mode for the vehicle for each of the plurality of route sections and determining a speed reference command of the vehicle based on at least one of the cruise control speed mode, the section length, the section grade, and a current speed. | 10-29-2015 |
Jan Forst, Plzen CZ
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20150233499 | Connecting Device, And Corresponding Thermal Exchanger, Particularly For A Motor Vehicle - The invention relates to a connecting device having a female part and a complementary male part, wherein the female part is a sleeve able to receive at least partially the associated male part with a gap between the sleeve and the male part for receiving a brazing material. The sleeve at least partially has a conical shape. The conical shape has a first substantially conical part having a complementary shape to the male part, with a first inclination angle with respect to a longitudinal axis of the sleeve. The conical shape also has a second substantially conical part with a second inclination angle with respect to the axis, with the second inclination angle being larger than the first inclination angle. | 08-20-2015 |
Janet Forst, Wilmington, DE US
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20090069340 | Pyrazolone Compounds As Metabotropic Glutamate Receptor Agonists For The Treatment Of Neurological And Psychiatric Disorders - Compounds of Formula (I), wherein R | 03-12-2009 |
John M. Forst, Draper, UT US
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20110098605 | FOOT FUNCTION SENSOR - A system for measuring the force of the feet of a user upon the support surface of an item of footwear for each foot at multiple locations has a plurality of sensors each predictably varying in resistance upon application of a force thereto. The sensors send signals reflective of the force to an A-D converter. The digitalized signals reflective of the resistance and in some cases deflection are sent to a receiver for storage in a memory and for further transmission to a computing device to compute and display the force at each of the multiple points. An accelerometer may also be combined proximate to or attached to the insert to supply signals reflective of the acceleration and which can be used to calculate and display other information including acceleration, speed and distance. | 04-28-2011 |
Jon K. Forst, Annapolis, MD US
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20090070247 | SYSTEM AND METHOD FOR DETERMINING ELEGIBILITY AND ENROLLING MEMBERS IN VARIOUS PROGRAMS - A system and method for determining eligibility of persons and enrolling those persons in various programs. For example, one embodiment is particularly suited for enrolling credit card members in payment programs. A program is selected, after which enrollment information is entered. The enrollment information is checked and verified, and the enrollment application is checked for eligibility. The enrollment may be either accepted or declined. The possibility of reiterative enrollment in more than one program is provided. A system is provided for tracking which payment programs are the most enticing for later feedback analysis. | 03-12-2009 |
20110238551 | SYSTEM AND METHOD FOR DETERMINING ELIGIBILITY AND ENROLLING MEMBERS IN VARIOUS PROGRAMS - A system and method for determining eligibility of persons and enrolling those persons in various programs. For example, one embodiment is particularly suited for enrolling credit card members in payment programs. A program is selected, after which enrollment information is entered. The enrollment information is checked and verified, and the enrollment application is checked for eligibility. The enrollment may be either accepted or declined. The possibility of reiterative enrollment in more than one program is provided. A system is provided for tracking which payment programs are the most enticing for later feedback analysis. | 09-29-2011 |
Juergen Forst, Hohenstein DE
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20150041385 | METHOD OF MANUFACTURING A CARTRIDGE FOR A FLUID TREATMENT SYSTEM - A method of manufacturing a cartridge ( | 02-12-2015 |
Klaus-Martin Forst, Zirndorf DE
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20080283091 | Method for Adding a Multi-Component Detergent Additve in a Water Leading Household Appliance - The invention relates to a method for adding a multi-component solid detergent additive during a program sequence of a water leading household appliance, in particular a dishwasher, wherein the household appliance comprises a compartment for storing the detergent additive. According to the invention, the liquid supply to the detergent additive stored in the compartment is effected in dependency of the program sequence, wherein in particular the liquid supply to the compartment is repeated at different times. Similarly a household appliance is provided with a device for adding a multi-component detergent additive. | 11-20-2008 |
20090211600 | DISHWASHER AND CORRESPONDING METHOD FOR OPERATING IT - The invention relates to a dishwasher comprising a washing chamber, a water collection sump, a circulation pump, a circulation filter system with a flat filter arranged between the washing chamber and the water collection sump and a discharge section arranged between a discharge pump and the washing chamber. | 08-27-2009 |
20110290804 | ADJUSTABLE RACK ASSEMBLY FOR A DISHWASHER BASKET - An adjustable rack assembly for a dishwasher basket, comprises a rack ( | 12-01-2011 |
20120222705 | DISHWASHER AND CORRESPONDING METHOD FOR OPERATING IT - The invention relates to a dishwasher comprising a washing chamber, a water collection sump, a circulation pump, a circulation filter system with a flat filter arranged between the washing chamber and the water collection sump and a discharge section arranged between a discharge pump and the washing chamber. | 09-06-2012 |
Klaus-Martin Forst, Gundelfingen DE
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20120222710 | DISHWASHER HAVING AN ADJUSTABLE UPPER BASKET - A dishwasher includes a washing container and an upper basket located in an upper region of the washing container for accommodating items to be washed. The upper basket has a floor wall and a side wall that circumferentially bounds the floor wall and projects upward. The upper basket has a static first partial region and a second partial region that is translationally displaceable between at least two positions relative to the first partial region and in parallel relation to the floor wall. The second partial region contains a section of the floor wall and exposes an opening in the floor wall in at least one of the two positions. | 09-06-2012 |
20120222711 | DISHWASHER HAVING AN ADJUSTABLE UPPER BASKET - A dishwasher includes a washing container, and an upper basket located in an upper region of the washing container for accommodating items to be washed. The upper basket has a floor wall and a side wall that circumferentially bounds the floor wall and projects upward. The upper basket has a static first partial region and a second partial region that is movable relative to the first partial region between at least two positions, with the second partial region forming in the at least two positions at least one section of the floor wall. The section assumes different heights relative to a part of the floor wall of the first partial region in the at least two positions, wherein the section assumes for at least one of the at least two positions a height above a height of the part of the floor wall of the first partial region. | 09-06-2012 |
20130133699 | HOUSEHOLD APPLIANCE AND A CONTROLLING METHOD FOR SUCH A HOUSEHOLD APPLIANCE - A household appliance includes a circulation pump for circulating dishwashing liquid in a washing compartment of the household appliance. A drain pump empties the dishwashing liquid from the washing compartment. For the purposes of ventilating the drain pump, a control device is provided to activate the drain pump after the washing compartment has been filled with the dishwashing liquid and before or during operation of the circulation pump. | 05-30-2013 |
Klaus-Martin Forst, Petersworth DE
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20130008477 | METHOD FOR FILLING A WASH TUB OF A DISHWASHER WITH WATER - A method for filling a wash tub ( | 01-10-2013 |
Klaus-Martin Forst, Peterswoerth DE
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20120037187 | METHOD FOR OPERATING A DISHWASHER - A method to operate a dishwasher, comprising: (1) adding detergent to a cleaning liquid which is circulated within the dishwasher; (2) measuring the conductivity of the cleaning liquid and determining the rate of change in conductivity caused by dissolution of the detergent in the cleaning liquid; (3) comparing the rate of change in conductivity with a predetermined threshold value so as to determine the dissolution rate of the detergent that has been added in step (A) to the cleaning liquid; and (4) adjusting operating parameters based on the determination of step (C). | 02-16-2012 |
20140150831 | DISHWASHER - The present invention relates to a dishwasher comprising at least one spray device ( | 06-05-2014 |
Klaus-Martin Forst, Wintersdorfer Strasse DE
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20110192426 | METHOD FOR OPERATING A DISHWASHER - A method for operating a dishwasher comprising a washing tub for accommodating articles to be cleaned and a circulation pump for circulating a cleaning liquid within the washing tub, and wherein there is provided for a plurality of washing programs selectable by the user, said washing programs comprising a series of consecutive steps selected from filling, pre-washing, washing, rinsing, soaking, draining and drying steps. In the method suggested herein, the washing programs comprise: (a) a first washing program in which the circulation pump is operated at a nominal speed, and (b) a second washing program in which, for at least part of the program, the circulation pump is operated at a speed which is reduced with respect to the nominal speed, and in which there is provided at least one soaking step during which the circulation pump is inactive. | 08-11-2011 |
Lutz Forst, Laupheim DE
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20100018155 | SEALING APPARATUS WITH SEALING LOAD CONTROL - An apparatus for sealing a cover film to a blister film having blisters holding respective small objects has a feed roll rotatable about an axis and formed with an array of radially outwardly open recesses arrayed like the blisters of the blister film. The blister film passes over the feed roll with the blisters in the recesses. A sealing roll is rotatable about an axis generally parallel to the feed-roll axis and presses the cover foil down against the blister foil on the feed roll. The feed roll is rotated to pull the films in a travel direction between the rolls so that the cover film is sealed to the blister film between the blisters thereof. A sensor detects movement of the sealing roll transversely of the feed-roll axis. A controller generates an output when the detected movement exceeds a threshold. | 01-28-2010 |
20110078981 | PACKAGING FOR PHARMACEUTICAL PRODUCTS AND METHOD AND DEVICE FOR ITS PRODUCTION - The device for the production of a packaging for pharmaceutical products includes a forming station for forming troughs in a nonstretchable cover sheet in a stepwise, individual, successive manner, and further includes a transport device for laying the formed cover sheet onto a bottom sheet. This bottom sheet has pockets, which serve to hold the pharmaceutical products, and webs arranged between the pockets, and at least portions of some of the webs have ridges corresponding to the shape of the troughs in the cover sheet. The device further includes a sealing station for sealing the cover sheet to the bottom sheet. This sealing station has two sealing plates shaped in correspondence with the troughs in the cover sheet, thus resulting in the sealing of the cover sheet to the bottom sheet also in the area of the ridges of the bottom sheet. | 04-07-2011 |
Matthew J. Forst, Oak Creek, WI US
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20110247651 | Fabric Sweeper - The present invention is a device for use in cleaning a fabric surface of dust, dirt, pet hair and other debris present on the surface. The device includes a housing coupled to a base. The base is coupled to at least one movable cleaning member configured to engage a surface for picking up debris from the surface. The debris is deposited into a debris collection chamber by way of interaction with another portion of the device. The debris collection chamber is selectively emptiable by an operator thereof so that the device may be subsequently reused. | 10-13-2011 |
20140007367 | Cleaning Device Having A Variable Size And Shape Head - A cleaning device includes a base having a first side and a second side. A first deployment element pivotally connects to the first side of the base and is pivotable from a stowed position to a deployed position. A second deployment element pivotally connects to the second side of the base and is pivotable from the stowed position to the deployed position. In the stowed position the base, the first deployment element, and the second deployment element define a substantially rectangular perimeter. In the deployed position, the base, the first deployment element, and the second deployment element define a substantially trapezoidal perimeter. | 01-09-2014 |
Thomas Forst US
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20100130402 | Biomarkers for insulin resistance and beta-cell dysfunction - The invention provides compositions and methods for determining insulin resistance and/or pancreatic β-cell dysfunction in a subject. The invention also provides compositions and methods for treating a subject according to the insulin resistance and/or pancreatic β-cell dysfunction in the subject. | 05-27-2010 |
20100130403 | Biomarkers for insulin efficacy - The invention provides compositions and methods for determining insulin efficacy in a subject. The invention also provides compositions and methods for treating a subject according to the efficacy of insulin in the subject. | 05-27-2010 |
20100130404 | Biomarkers for cardiodiabetes - The invention provides compositions and methods for determining cardiodiabetes status in a subject. The invention also provides compositions and methods for treating a subject experiencing cardiodiabetes. | 05-27-2010 |
20100209350 | Biomarkers for Adipose Tissue Activity - The invention provides compositions and methods for determining a subject's adipose tissue activity. In one embodiment, the composition comprises a solid support comprising probes for measuring a biomarker panel comprising, for example, adiponectin, resistin, PAI-1, optionally leptin and optionally visfatin. The simultaneous use of multiple biomarkers with independent classification power will increase the performance of the biomarker panel in identifying adipose tissue activity, which is associated with various disease states including chronic or systemic inflammation, atherosclerosis and other cardiovascular risks and complications. The invention also provides methods of treating a subject and determining the efficacy of a therapy through assaying the various biomarkers of a biomarker panel disclosed herein. | 08-19-2010 |
Thomas Forst, Mainz DE
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20110118134 | Biomarkers for insulin sensitizer drug response - The invention provides compositions and methods for determining insulin sensitizer drug response in a subject. The invention also provides compositions and methods for treating a subject according to insulin sensitizer drug response. | 05-19-2011 |
20110177537 | Method and System for Measuring a Sample to Determine the Presence of and Optionally Treat a Pathologic Condition - The present invention provides diagnostic in vitro methods as well as kits and devices to be used in the methods of the present invention for diagnosis or prognosis of a pathologic condition characterized by the presence/absence of an endogenous hormone and/or hormone analog(s) thereof involved in diabetes or metabolic syndrome. The methods comprise a quantitative separation of at least those analytes of interest whose common presence interferes with measuring the presence/absence or concentration of one of the analytes of interest by a subsequent analytical method. | 07-21-2011 |
20130137632 | Method of Treating a Subject According to Biomarkers for Insulin Resistance - The invention provides compositions and methods for determining insulin resistance and/or pancreatic β-cell dysfunction in a subject. The invention also provides compositions and methods for treating a subject according to the insulin resistance and/or pancreatic β-cell dysfunction in the subject. | 05-30-2013 |
20130210718 | Biomarkers for Cardiodiabetes - The invention provides compositions and methods for determining cardiodiabetes status in a subject. The invention also provides compositions and methods for treating a subject experiencing cardiodiabetes. | 08-15-2013 |
20150219639 | Method of Treating a Subject According to Biomarkers for Insulin Resistance - The invention provides compositions and methods for determining insulin resistance and/or pancreatic β-cell dysfunction in a subject. The invention also provides compositions and methods for treating a subject according to the insulin resistance and/or pancreatic β-cell dysfunction in the subject. | 08-06-2015 |