Patent application number | Description | Published |
20100047174 | AAV CAPSID LIBRARY AND AAV CAPSID PROTEINS - Recombinant adeno-associated viral (AAV) capsid proteins are provided. Methods for generating the recombinant adeno-associated viral capsid proteins and a library from which the capsids are selected are also provided. | 02-25-2010 |
20120066783 | AAV CAPSID LIBRARY AND AAV CAPSID PROTEINS - Recombinant adeno-associated viral (AAV) capsid proteins are provided. Methods for generating a library of recombinant adeno-associated viral capsid proteins are also provided. | 03-15-2012 |
20120255046 | IN VIVO TRANSDUCTION WITH A CHIMERIC AAV CAPSID PROTEIN - Recombinant adeno-associated viral (AAV) capsid proteins are provided. Methods for generating a library of recombinant adeno-associated viral capsid proteins are also provided. | 10-04-2012 |
20150057189 | IN VIVO TRANSDUCTION WITH A CHIMERIC AAV CAPSID PROTEIN - Recombinant adeno-associated viral (AAV) capsid proteins are provided. Methods for generating a library of recombinant adeno-associated viral capsid proteins are also provided. | 02-26-2015 |
20160053282 | Self-Complementary Parvoviral Vectors, and Methods for Making and Using the Same - The teachings herein are generally directed to a method of enhancing the genetic stability of parvovirus vectors. The stability of conventional ss or dsAAV vector constructs can be enhanced, for example, to obtain a concurrent increase in vector titer and purity, as well as an improvement in vector safety, due at least in part to the elimination of stuffer DNA from the AAV vector. The method is broadly applicable to all gene transfer/therapy applications, such as those requiring delivery of foreign DNA containing recombinant gene expression cassettes. Such foreign DNA can range, for example, from about 0.2 up to about 5.2 kb in length. The enhanced vector constructs are highly flexible, user-friendly, and can be easily modified (via routine DNA cloning) and utilized (via standard AAV vector technology) by anyone skilled in the art. | 02-25-2016 |
Patent application number | Description | Published |
20110000162 | Interlocking Floor Tiles with Mushroom Shaped Connectors - An interlocking tile system comprises tiles that has a body, interlocking cap structure with a first surface and a second surface; a first curved portion connecting the first surface with a radius of R | 01-06-2011 |
20110186533 | Modular Overhead Storage - A storage system comprises a rack of multiple platforms connectable to one another in a first direction, where each of the platforms has segments that connect to one another along a direction other than the first direction, via a user-operable coupling. The platforms are preferably rectangular, and are connected at their long ends. The segments of each platform are also preferably rectangular, but they are connected along their long sides. In such embodiments, the connection between platforms is perpendicular to the length of the rack, while the connection between segments is parallel to the length of the rack. The segments of individual platforms are preferably coupled together with snap fit connections, and supported from their undersides by transverse supports, and the transverse supports are supported from their undersides by longitudinal supports via recesses on the segments. The transverse supports are preferably perpendicular to the longitudinal supports. | 08-04-2011 |
20120304566 | Floor Tiles with Hybrid Interlocking System - A floor tile system for protecting a substrate is described. The system includes two tiles or mats that interlock with one another along numerous axes to provide a tight, high-strength seam. Specifically, the tiles include teeth that interlock with teeth of the other tile in a side-by-side manner. The tiles also include male and female portions that interlock when the tile edges overlap with one another. | 12-06-2012 |
20130123079 | INTEGRATED PORTABLE EXERCISE DEVICE - The present invention provides an exercise device configured to engage multiple accessory attachments, the device comprising: a top plate; a bottom plate underneath and complementary to the top plate; and a first accessory disk releasably attached to the top plate, the first accessory disk having a member engaging a user for performing exercises, the accessory attachments capable of being configured in various combinations for allowing the user to perform different exercises targeting different muscle groups of the body, thereby to achieve a full body exercise. | 05-16-2013 |
20140138333 | Modular Overhead Storage - A storage system comprises a rack of multiple platforms connectable to one another in a first direction, where each of the platforms has segments that connect to one another along a direction other than the first direction, via a user-operable coupling. The platforms are preferably rectangular, and are connected at their long ends. The segments of each platform are also preferably rectangular, but they are connected along their long sides. In such embodiments, the connection between platforms is perpendicular to the length of the rack, while the connection between segments is parallel to the length of the rack. The segments of individual platforms are preferably coupled together with snap fit connections, and supported from their undersides by transverse supports, and the transverse supports are supported from their undersides by longitudinal supports via recesses on the segments. The transverse supports are preferably perpendicular to the longitudinal supports. | 05-22-2014 |
20150189986 | Modular Overhead Storage - A storage system comprises a rack of multiple platforms connectable to one another in a first direction, where each of the platforms has segments that connect to one another along a direction other than the first direction, via a user-operable coupling. The platforms are preferably rectangular, and are connected at their long ends. The segments of each platform are also preferably rectangular, but they are connected along their long sides. In such embodiments, the connection between platforms is perpendicular to the length of the rack, while the connection between segments is parallel to the length of the rack. The segments of individual platforms are preferably coupled together with snap fit connections, and supported from their undersides by transverse supports, and the transverse supports are supported from their undersides by longitudinal supports via recesses on the segments. The transverse supports are preferably perpendicular to the longitudinal supports. | 07-09-2015 |
Patent application number | Description | Published |
20100123443 | Hybrid power converter - Power converter circuits, structures, and methods are disclosed herein. In one embodiment, a hybrid converter can include: (i) a first switching device controllable by a control signal; (ii) an inductor coupled to the first switching device and an output; and (iii) a control circuit configured to receive feedback from the output for generation of the control signal to control the first switching device, where the control circuit includes a first detection circuit configured to detect first and second output conditions, the control circuit being configured to operate the first switching device in a switch control in response to the control signal when the first output condition is detected, and to operate the first switching device in a linear control region when the second output condition is detected. | 05-20-2010 |
20100301827 | Control for regulator fast transient response and low EMI noise - Methods and circuits for power supply arrangement and control are disclosed herein. In one embodiment, a switching regulator can include: (i) a filter network coupled to an output terminal, where an output voltage is generated at the output terminal from an input source; (ii) an active switch to connect the input source to the filter network by periodically operating between on and off states over a switching period, where a duty cycle of the on state relative to the switching period is modulated based on a PWM control signal; (iii) a comparator receiving an output feedback signal, a hysteresis signal, and a reference level, and providing the PWM control signal therefrom; and (iv) a hysteresis programming circuit generating the hysteresis signal, and a ramp control signal, where the hysteresis signal is programmed based on conditions at the input source and the output voltage to achieve a pseudo constant frequency operation. | 12-02-2010 |
20120019220 | HYBRID POWER CONVERTER - Power converter circuits, structures, and methods are disclosed herein. In one embodiment, a hybrid converter can include: (i) a first switching device controllable by a control signal; (ii) an inductor coupled to the first switching device and an output; and (iii) a control circuit configured to receive feedback from the output for generation of the control signal to control the first switching device, where the control circuit includes a first detection circuit configured to detect first and second output conditions, the control circuit being configured to operate the first switching device in a switch control in response to the control signal when the first output condition is detected, and to operate the first switching device in a linear control region when the second output condition is detected. | 01-26-2012 |
20120153922 | CONTROL FOR REGULATOR FAST TRANSIENT RESPONSE AND LOW EMI NOISE - Methods and circuits for power supply arrangement and control are disclosed herein. In one embodiment, a switching regulator can include: (i) a filter network coupled to an output terminal, where an output voltage is generated at the output terminal from an input source; (ii) an active switch to connect the input source to the filter network by periodically operating between on and off states over a switching period, where a duty cycle of the on state relative to the switching period is modulated based on a PWM control signal; (iii) a comparator receiving an output feedback signal, a hysteresis signal, and a reference level, and providing the PWM control signal therefrom; and (iv) a hysteresis programming circuit generating the hysteresis signal, and a ramp control signal, where the hysteresis signal is programmed based on conditions at the input source and the output voltage to achieve a pseudo constant frequency operation. | 06-21-2012 |
20130154710 | ADAPTIVE CASCODE CIRCUIT USING MOS TRANSISTORS - The present invention relates to a cascode circuit using MOS transistors. In one embodiment, an adaptive cascode circuit can include: (i) a main MOS transistor; (ii) n adaptive MOS transistors coupled in series to the drain of the main MOS transistor, where n can be an integer greater than one; (iii) a shutdown clamping circuit connected to the gates of the n adaptive MOS transistors, where the shutdown clamping circuit may have (n+1) shutdown clamping voltages no larger than rated gate-drain voltages of the main MOS transistor and n adaptive MOS transistors; and (iv) n conduction clamping circuits coupled correspondingly to the gates of the adaptive MOS transistors, where the n conduction clamping circuits may have n conduction clamping voltages no larger than the conduction threshold voltages of the adaptive MOS transistors. | 06-20-2013 |
20140002051 | ADAPTIVE CASCODE CIRCUIT USING MOS TRANSISTORS | 01-02-2014 |
Patent application number | Description | Published |
20090198487 | Community Translation On A Social Network - Embodiments of the invention provide techniques for translating text in a social network. In one embodiment translations of text phrases are received from members of the social network. These text phrases include content displayed in a social networking system, such as content from social networking objects. A particular member is provided with content including a text phrase in a first language, and the member requests translation into another language. Responsive to this request, a translation of the text phrase is selected from a set of available translations. The selection is based on actions by friends of the member in the social network, the actions being associated with the set of available translations. These actions can the viewing of or approval of translations by the friends, for example. The selected translation is then presented to the member requesting the translation. | 08-06-2009 |
20120310624 | Community Translation On A Social Network - Embodiments of the invention provide techniques for translating text in a social network. In one embodiment translations of text phrases are received from members of the social network. These text phrases include content displayed in a social networking system, such as content from social networking objects. A particular member is provided with content including a text phrase in a first language, and the member requests translation into another language. Responsive to this request, a translation of the text phrase is selected from a set of available translations. The selection is based on actions by friends of the member in the social network, the actions being associated with the set of available translations. These actions can the viewing of or approval of translations by the friends, for example. The selected translation is then presented to the member requesting the translation. | 12-06-2012 |
20130289972 | Community Translation on a Social Network - Embodiments of the invention provide techniques for translating text in a social network. In one embodiment translations of text phrases are received from members of the social network. These text phrases include content displayed in a social networking system, such as content from social networking objects. A particular member is provided with content including a text phrase in a first language, and the member requests translation into another language. Responsive to this request, a translation of the text phrase is selected from a set of available translations. The selection is based on actions by friends of the member in the social network, the actions being associated with the set of available translations. These actions can the viewing of or approval of translations by the friends, for example. The selected translation is then presented to the member requesting the translation. | 10-31-2013 |
Patent application number | Description | Published |
20100025555 | Personal accessory hanger - A cantilever, gravity hanger for holding by hanging a personal accessory, operatively attachable to, or integrated with, such an accessory. The hanger, in an operative condition poised for holding such an accessory, includes (a) an elongate central body, (b) a pair of spaced, elongate arms joined to opposite ends of the body, and extending laterally outwardly from a common side of the body in diverging relation to one another, and (c) accessory-connection traveler structure including a traveler carried captively on, and shiftable freely and reversibly along the length of, one of the arms. | 02-04-2010 |
20130237891 | ORTHOTIC BRACE TIGHTENING DEVICE - The invention is a back brace with a stacked pulley tightening device that allows a user to quickly, efficiently, and easily tighten the back brace around the user after the back brace is donned. The pulleys provide a mechanical advantage. Additionally, the present invention includes a segmented belt portion such that a single pulley tightening device can be used to tighten around users of any size. | 09-12-2013 |
Patent application number | Description | Published |
20100133746 | System and Method For Providing A Table Game - A system and method for providing a table game are disclosed. According to one embodiment, an apparatus comprises a playing field, a ball launcher mechanism launching a ball into the playing field, and the ball launcher mechanism allows a first player to select one or more attributes affecting a ball trajectory. The apparatus further comprises a ball striker mechanism controlling a ball striker. The ball striker placed at a distance from the ball launcher mechanism in the playing field has a bat to hit a ball launched by the ball launcher mechanism and is controlled by a second player. One or more sensors are placed in predetermined locations in the playing field. The electrical signals generated by the one or more sensors are used to update a status of a game. | 06-03-2010 |
20130193644 | SYSTEM AND METHOD FOR PROVIDING A TABLE GAME - A system and method for providing a table game are disclosed. According to one embodiment, an apparatus comprises a playing field, a ball launcher mechanism launching a ball into the playing field, and the ball launcher mechanism allows a first player to select one or more attributes affecting a ball trajectory. The apparatus further comprises a ball striker mechanism controlling a ball striker. The ball striker placed at a distance from the ball launcher mechanism in the playing field has a bat to hit a ball launched by the ball launcher mechanism and is controlled by a second player. One or more sensors are placed in predetermined locations in the playing field. The electrical signals generated by the one or more sensors are used to update a status of a game. | 08-01-2013 |
20140035226 | SYSTEM AND METHOD FOR PROVIDING A TABLE GAME - A mechanical ball launcher for a table game is disclosed. According to one embodiment, the mechanical ball launcher has a body that rotates about a first axis. The body has a launch arm that extends along a second axis that is substantially perpendicular to the first axis. The launch arm has a ball receptacle at a terminal end. The mechanical ball launcher has a supporting plate supporting the body and a mechanical spring connected between the body and the supporting plate. The mechanical spring is placed in a loaded position when the launch arm is pulled back. A launch angle, a lateral angle, and a speed of the ball are adjusted as the ball is launched from the ball receptacle of the mechanical ball launcher. | 02-06-2014 |
20150251084 | System and Method for Providing a Table Game - A system and method for providing a table game are disclosed. According to one embodiment, an apparatus comprises a playing field, a ball launcher mechanism launching a ball into the playing field, and the ball launcher mechanism allows a first player to select one or more attributes affecting a ball trajectory. The apparatus further comprises a ball striker mechanism controlling a ball striker. The ball striker placed at a distance from the ball launcher mechanism in the playing field has a bat to hit a ball launched by the ball launcher mechanism and is controlled by a second player. One or more sensors are placed in predetermined locations in the playing field. The electrical signals generated by the one or more sensors are used to update a status of a game. | 09-10-2015 |
20160089804 | Device and Method for Creating Partial Cuts in Food Products - A device for creating partial cuts, such as transverse spiral cuts, into an elongated food product, such as hot dogs, frankfurters, and wieners, the device having an upper housing section with at least one top blade and a lower housing section with at least one bottom blade, wherein closing the top housing on top of the lower housing with the elongated food product inside allows the top blades and the bottom blades to partially cut through the elongated food product creating a helical groove pattern around the outer surface of the elongated food product while leaving an inner core intact. The device may also have guide channels to guide a skewer through the inner core for easy removal of the food product from the housing. The device can also be provided as a kit with skewers, modified tongs, and a heating unit to cook the food product in the housing. | 03-31-2016 |